Pruritus measurement and treatment.

Abstract:

:Pruritus measurement is problematic, because of its subjective nature and poor localization. Ratio scales enhance the usefulness of the visual analogue scale (VAS) by reducing variation; other scales such as the generalized labelled magnitude scale may also be useful. Pruritus neuroanatomy includes peripheral receptors, peripheral and central nerves, ascending and descending spinal pathways, and several brain regions. Pruritus receptors include Merkel discs and free nerve endings, and itch receptors have fast or slow adaptation. In this review, we discuss the pathophysiology of pruritus in atopic dermatitis, psoriasis and scabies. Pruritus treatment is reviewed for topical agents and antihistamines. Future research directions are suggested.

journal_name

Clin Exp Dermatol

authors

Langner MD,Maibach HI

doi

10.1111/j.1365-2230.2009.03218.x

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

285-8

issue

3

eissn

0307-6938

issn

1365-2230

pii

CED3218

journal_volume

34

pub_type

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