A trial of accelerated PUVA in psoriasis.

abstract：:A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...

journal_title：Clinical and experimental dermatology

authors： Happle R

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The motivations for patients presenting to melanoma screening clinics (MSCs) with concerning skin lesions are poorly understood. Social media (SoMe) refers to online platforms designed to facilitate sharing of information with billions of users worldwide. There is evidence of patients posting skin lesion 'se...

journal_title：Clinical and experimental dermatology

authors： Guckian J,Jobling K,Oliphant T,Weatherhead S,Blasdale K

更新日期：2020-04-01 00:00:00

abstract：:Although many antihistamines are now in clinical use, few studies directly compare their pharmacodynamic and sedative activities in humans in vivo. We designed a double-blind, placebo-controlled, crossover study to compare the inhibitory effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-in...

journal_title：Clinical and experimental dermatology

authors： Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2004-09-01 00:00:00

abstract：:A finger-tip unit (FTU) is the amount of ointment expressed from a tube with a 5 mm diameter nozzle, applied from the distal skin-crease to the tip of the index finger. Thirty adult-patients treated various anatomical regions using FTU's of ointment. The number of FTU's required was: face and neck 2.5 (s.d. +/- 0.8); ...

journal_title：Clinical and experimental dermatology

authors： Long CC,Finlay AY

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Interferons are molecules with antiviral effects, which have been used for the treatment of verruca for many years. AIMS:To determine if sublesional interferon (IFN)-alpha injection offers an effective alternative treatment for common warts. METHODS:We compared the results of single-dose sublesional IFN ap...

journal_title：Clinical and experimental dermatology

authors： Aksakal AB,Ozden MG,Atahan C,Onder M

更新日期：2009-01-01 00:00:00

abstract：:Sweet's syndrome (acute febrile neutrophilic dermatosis, SS) may be considered a reactional dermatosis with numerous associated diseases. We describe a rare association between SS and acute sarcoidosis in a 55-year-old woman. The atypical feature of positive tuberculin reaction is discussed. In this association, diagn...

journal_title：Clinical and experimental dermatology

authors： Dadban A,Hirschi S,Sanchez M,Lagrange B

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Epidemiological and clinical data suggest that actinic damage to the skin is an important predictor of skin carcinogenesis. AIM:To investigate the association of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) with sun-damage alterations seen by histopathology. METHOD:In the current prospectiv...

journal_title：Clinical and experimental dermatology

authors： Apalla Z,Calzavara-Pinton P,Lallas A,Argenziano G,Kyrgidis A,Crotti S,Facchetti F,Monari P,Gualdi G

更新日期：2016-01-01 00:00:00

abstract：:We report the cases of two patients who developed generalized pustular psoriasis on the withdrawal of oral Cyclosporin treatment for persistent palmoplantar pustulosis. This complication does not appear to have been reported previously. ...

journal_title：Clinical and experimental dermatology

authors： De Silva BD,Benton EC,Tidman MJ

更新日期：1999-01-01 00:00:00

abstract：:Clear cell acanthoma (CCA) is a benign epidermal tumour with distinctive and uniform clinical and histological features. Although solitary lesions are the rule, some cases of multiple CCA, rarely with more than 10 lesions, have been previously reported. Only 22 cases of multiple CCA have been described in the English ...

journal_title：Clinical and experimental dermatology

authors： Innocenzi D,Barduagni F,Cerio R,Wolter M

更新日期：1994-05-01 00:00:00

abstract：:We report a rare case of cutaneous abscess by Trichosporon asahii in an immunocompetent adult. A 31-year-old Korean woman presented to our hospital with a cutaneous abscess. She had received an intralesional steroid injection 4 months earlier on the site of a hypertrophic scar. Direct sequencing of the intergenic spac...

journal_title：Clinical and experimental dermatology

authors： Yun SJ,Lee JB,Shin MG,Kim SJ,Won YH,Lee SC

更新日期：2006-07-01 00:00:00

abstract：:Incipient osteomalacia developed in a Pakistani patient living in the UK after strict sunlight avoidance forming part of the management of the photosensitivity disorder, chronic actinic dermatitis. The patient's skin type and diet, which included calcium-binding phytates in chappattis, had increased his risk of the co...

journal_title：Clinical and experimental dermatology

authors： Kapur N,Creamer D,Hawk J

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The dorsum of the hand is a common site for squamous cell carcinoma, and excision with appropriate margins often results in surgical defects that cannot be repaired by primary side-to-side closure. AIM:To assess healing time, complications and resulting scars when surgical wounds on the dorsum of the hand w...

journal_title：Clinical and experimental dermatology

authors： Lateo SA,Langtry JA

更新日期：2013-08-01 00:00:00

abstract：:Imprinting is the process whereby genetic alleles responsible for a phenotype are derived from one parent only. It is an epigenetic phenomenon resulting from DNA methylation or modification of protruding histones. When imprinted genes are disrupted, syndromes with characteristic patterns of inheritance and multisystem...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-09-01 00:00:00

abstract：:Angiolymphoid hyperplasia with eosinophilia (AHE) is a benign reactive vascular lesion characterized by a proliferation of small to medium sized vascular structures lined by epithelioid endothelial cells. We report a 75-year-old woman with a 1-month history of a painful ulcer on the tongue. Histopathological findings ...

journal_title：Clinical and experimental dermatology

authors： Garrido-Ríos AA,Sanz-Muñoz C,Torrero-Antón MV,Martínez-García G,Miranda-Romero A

更新日期：2009-12-01 00:00:00

abstract：:Despite the negative effects of androgenetic alopecia (AGA), no standardized health-related quality of life (HRQOL) questionnaire which is both specific to women and suitable for use in clinical trials currently exists. A questionnaire to assess HRQOL in women with AGA, the Women's Androgenetic Alopecia Quality of Lif...

journal_title：Clinical and experimental dermatology

authors： Dolte KS,Girman CJ,Hartmaier S,Roberts J,Bergfeld W,Waldstreicher J

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Therapeutics targeting tumour necrosis factor (TNF)-α are effective for psoriasis; however, in patients treated for other disorders, psoriasis may worsen and psoriasiform dermatitis (PsoD) may arise. T helper (Th) cytokines in psoriasis upregulate keratin (K)17, which modulates TNF-α transduction, leading to...

journal_title：Clinical and experimental dermatology

authors： Moy AP,Murali M,Kroshinsky D,Horn TD,Nazarian RM

更新日期：2018-01-01 00:00:00

abstract：:Hydroxyurea is an anti-tumour agent most commonly used to treat chronic myeloproliferative disorders in doses up to 4 g per day. Dermatological adverse effects reported so far have been observed predominantly in these patients. As we are treating selected psoriasis patients with low dose hydroxyurea we attempted to de...

journal_title：Clinical and experimental dermatology

authors： Kumar B,Saraswat A,Kaur I

更新日期：2002-01-01 00:00:00

abstract：:Pruritus measurement is problematic, because of its subjective nature and poor localization. Ratio scales enhance the usefulness of the visual analogue scale (VAS) by reducing variation; other scales such as the generalized labelled magnitude scale may also be useful. Pruritus neuroanatomy includes peripheral receptor...

journal_title：Clinical and experimental dermatology

authors： Langner MD,Maibach HI

更新日期：2009-04-01 00:00:00

abstract：:Postinflammatory hypopigmentation is a common cause of acquired hypopigmentary disorders. It can be a result of cutaneous inflammation, injury or dermatological treatment. There are also many specific conditions that present with hypopigmentation other than postinflammatory hypopigmentation. Most cases of postinflamma...

journal_title：Clinical and experimental dermatology

authors： Vachiramon V,Thadanipon K

更新日期：2011-10-01 00:00:00

abstract：:Piloleiomyoma is a benign tumour originating in the smooth muscles of the arrector pili muscle in the skin. The lesions are often sensitive to touch, cold and emotional disturbance. We present a patient with multiple piloleiomyoma (MPL) of the submentum who underwent reconstructive surgery using a submental perforator...

journal_title：Clinical and experimental dermatology

authors： Matsushita S,Ishihara T,Takeda K,Uchida Y,Tamai M,Usuki K,Kanekura T

更新日期：2009-12-01 00:00:00

abstract：:Down's syndrome (DS) is associated with rare dermatological disorders and increased frequency of some common dermatoses. Owing to advances in medical care and changes in attitude, the median age of death in this population has increased to 49 years, and the life expectancy of a 1-year-old person with DS today is more ...

journal_title：Clinical and experimental dermatology

authors： Madan V,Williams J,Lear JT

更新日期：2006-09-01 00:00:00

abstract：:Whole-body ultraviolet (UV)A1 (340-400 nm) phototherapy was first introduced 30 years ago, but is currently available in the UK in only three dermatology departments. A workshop to discuss UVA1 was held by the British Photodermatology Group in May 2009, the aim of which was to provide an overview of UVA1 phototherapy ...

journal_title：Clinical and experimental dermatology

authors： Kerr AC,Ferguson J,Attili SK,Beattie PE,Coleman AJ,Dawe RS,Eberlein B,Goulden V,Ibbotson SH,Menage Hdu P,Moseley H,Novakovic L,Walker SL,Woods JA,Young AR,Sarkany RP

更新日期：2012-04-01 00:00:00

abstract：:Complete deficiency of the fourth component of complement (C4) is an extremely rare condition. However, it has been reported that partial C4 deficiency can occur in normal subjects, and is associated with several immune diseases. We report a 44-year-old woman who developed slight oedema and punctate purpura on her low...

journal_title：Clinical and experimental dermatology

authors： Kosaka S,Osada S,Kaneko T,Nishimura S,Kawana S

更新日期：2013-07-01 00:00:00

abstract：:We investigated skin biopsies from pemphigus vulgaris (PV) patients by light, fluorescent and electron microscopy in order to study the ultrastructural appearances of epidermis at the pre-acantholytic stage. The biopsies were obtained from uninvolved forearm skin in 10 patients with PV in the acute stage of the diseas...

journal_title：Clinical and experimental dermatology

authors： Grando SA,Terman AK,Stupina AS,Glukhenky BT,Romanenko AB

更新日期：1991-09-01 00:00:00

abstract：:Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intrig...

journal_title：Clinical and experimental dermatology

authors： Sethuraman G,Srinivas CR,D'Souza M,Thappa DM,Smiles L

更新日期：2002-09-01 00:00:00

abstract：:Anti-tumour necrosis factor (anti-TNF) therapies have been associated with neurological complications, including in rare cases demyelinating disease. It is currently unknown whether patients who have received more than one immunosuppressive agent or anti-TNF have a greater risk of demyelination. We report the case of ...

journal_title：Clinical and experimental dermatology

authors： Boggs JME,Barnes L

更新日期：2018-07-01 00:00:00

abstract：:This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

journal_title：Clinical and experimental dermatology

authors： Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

更新日期：1996-01-01 00:00:00

abstract：:Multiple dermatofibromas (DFs) are rare and have been thought to be associated with altered immunity. In this report, we describe a 27-year-old Japanese woman with systemic lupus erythematosus (SLE) and Sjögren's syndrome in whom eight nodules appeared over a period of 4 years. Histopathological findings were consiste...

journal_title：Clinical and experimental dermatology

authors： Tsunemi Y,Tada Y,Saeki H,Ihn H,Tamaki K

更新日期：2004-09-01 00:00:00

abstract：:Tetracyclines, including doxycycline, are widely used drugs that form an integral part of daily prescribing, and serious adverse reactions (SARs) are rarely reported. The frequency of hypoglycaemia complicating tetracycline treatment remains unknown, and is not a recognized complication. We describe an 80-year-old man...

journal_title：Clinical and experimental dermatology

authors： Tan CH,Shelley C,Harman KE

更新日期：2016-01-01 00:00:00

abstract：:We describe a patient with intermittent unilateral hyperhidrosis localized to the left hand only. Histology confirmed the presence of an eccrine naevus. ...

journal_title：Clinical and experimental dermatology

authors： Parslew R,Lewis-Jones MS

更新日期：1997-09-01 00:00:00