Abstract:
:Multiple dermatofibromas (DFs) are rare and have been thought to be associated with altered immunity. In this report, we describe a 27-year-old Japanese woman with systemic lupus erythematosus (SLE) and Sjögren's syndrome in whom eight nodules appeared over a period of 4 years. Histopathological findings were consistent with DF. SLE rather than Sjögren's syndrome seemed to have induced the multiple DFs in this patient. We also reviewed the reported cases with multiple DFs associated with SLE and/or Sjögren's syndrome. Review of the previous reports indicates that SLE is the most frequent autoimmune disorder associated with multiple DFs, and that both SLE and immunosuppressive treatments play a part in induction of multiple DFs. Therefore, if multiple DFs are present it is important that the status of the patient be evaluated from the standpoint of autoimmune diseases, particularly SLE, or immunosuppression.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Tsunemi Y,Tada Y,Saeki H,Ihn H,Tamaki Kdoi
10.1111/j.1365-2230.2004.01574.xkeywords:
subject
Has Abstractpub_date
2004-09-01 00:00:00pages
483-5issue
5eissn
0307-6938issn
1365-2230pii
CED1574journal_volume
29pub_type
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