Paracetamol-induced fixed drug eruption with positive immunofluorescence findings.

Abstract:

:A 93-year-old woman with an 8-year history of episodes of fixed drug eruption due to paracetamol is described. The rash was characterized by bullae, crusted lesions, hyperpigmented and erythematous patches as well as lesions resembling toxic epidermal necrolysis. Direct immunofluorescence revealed deposition of IgG and C3 in the epidermal intercellular cement substance of lesional skin only; the pathogenetic significance of this finding is discussed.

journal_name

Clin Exp Dermatol

authors

Duhra P,Porter DI

doi

10.1111/j.1365-2230.1990.tb02093.x

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

293-5

issue

4

eissn

0307-6938

issn

1365-2230

journal_volume

15

pub_type

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