Stevens-Johnson syndrome and toxic epidermal necrolysis due to anticonvulsants share certain clinical and laboratory features with drug-induced hypersensitivity syndrome, despite differences in cutaneous presentations.

abstract：:Common unifying features of the subepidermal blistering diseases are the presence of tense blisters clinically and demonstration by immunofluorescence of linear deposition of immunoreactants along the dermoepidermal junction. Further characterization of subtype is possible by identification of the target antigen by im...

journal_title：Clinical and experimental dermatology

authors： Rao R,Bhogal B,Groves R

更新日期：2013-04-01 00:00:00

abstract：:Recessive dystrophic epidermolysis bullosa (RDEB; OMIM #226600) is one of the most devastating subtypes of epidermolysis bullosa, a group of skin and mucous membrane blistering disorders often associated with extracutaneous manifestations. RDEB is caused by mutations in COL7A1, the gene encoding type VII collagen (C7)...

journal_title：Clinical and experimental dermatology

authors： Saeidian AH,Youssefian L,Moreno Trevino MG,Fortuna G,Vahidnezhad H,Atanasova VS,Uitto J,Salas-Alanis JC,South AP

更新日期：2018-07-01 00:00:00

abstract：:Lupus miliaris disseminatus faciei (LMDF) is a chronic and uncommon inflammatory dermatosis, characterized by yellowish-red papules, especially on the face and around the eyelids. It is considered to be a reaction to destroyed hair follicles. We dermoscopically evaluated two patients diagnosed with LMDF. Dermoscopy re...

journal_title：Clinical and experimental dermatology

authors： Ayhan E,Alabalik U,Avci Y

更新日期：2014-06-01 00:00:00

abstract：:Postgraduate higher specialist training of dermatology in the UK has become more structured over the past 8 years. Increased awareness of the need to police our profession has impelled the introduction of objective competency based assessment. Competency assessment will take three forms: mini clinical evaluation exerc...

journal_title：Clinical and experimental dermatology

authors： Griffiths CE

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Momordica charantia (MC; bitter gourd) is a traditional herb commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. It is also used for the rapid healing of wounds. AIM:To observe the topical effect of MC extract on the wound-healing process in rats with diabetes induce...

journal_title：Clinical and experimental dermatology

authors： Teoh SL,Latiff AA,Das S

更新日期：2009-10-01 00:00:00

abstract：:In 1990 we reported the trends in presentation of malignant melanoma (MM) from 1986 to 1988 in a defined population in South Wales. Ten years after this initial study we reassessed the incidence of invasive MM in this defined population over a similar 3 year period. Using the local skin cancer registry we identified 1...

journal_title：Clinical and experimental dermatology

authors： Holme SA,Malinovsky K,Roberts DL

更新日期：2001-09-01 00:00:00

abstract：:We present two patients who developed pseudoporphyria whilst taking isotretinoin (Roaccutane). At that time, both patients were receiving other agents which could be incriminated as causing their pseudoporphyria. However, it is significant that these other agents had been longstanding and that the porphyria-like cutan...

journal_title：Clinical and experimental dermatology

authors： Riordan CA,Anstey A,Wojnarowska F

更新日期：1993-01-01 00:00:00

abstract：:Vitiligo is a disease characterized by the loss of melanocytes, resulting in progressive depigmentation of skin, and areas of normally pigmented skin can be of cosmetic concern. Several options have been tried to remove the pigment and make the skin a more even colour. We present an easy and effective therapeutic proc...

journal_title：Clinical and experimental dermatology

authors： Di Nuzzo S,Masotti A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：:A whole array of cutaneous syndromes is associated with distinct dominant mutations in GJB2 encoding the gap junction protein connexin 26 (C x 26), including Vohwinkel's syndrome and keratitis-ichthyosis-deafness syndrome. In contrast, recessive GJB2 mutations occur in a large proportion of individuals with hearing lo...

journal_title：Clinical and experimental dermatology

authors： Common JE,Bitner-Glindzicz M,O'Toole EA,Barnes MR,Jenkins L,Forge A,Kelsell DP

更新日期：2005-11-01 00:00:00

abstract：:Summary Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon benign vascular tumour. It presents with small, dull red papules or nodules usually on the ears and preauricular areas and only 20% of lesions are multiple. We report a case of multiple scattered lesions of ALHE in a patient who subsequently dev...

journal_title：Clinical and experimental dermatology

authors： Shankar S,Russell-Jones R

更新日期：2004-07-01 00:00:00

abstract：:Three patients with subungual exostoses, two involving the great toe and one the fourth toe, are presented. Local excision was performed, and the specimens were processed for light and electron microscopy. Light-microscopic study revealed that the tumours consisted of a proliferative fibrocartilaginous cap that merged...

journal_title：Clinical and experimental dermatology

authors： Kato H,Nakagawa K,Tsuji T,Hamada T

更新日期：1990-11-01 00:00:00

abstract：:We report a patient with chronic urticaria which was closely associated with elevated levels of thyroxine. The urticaria responded poorly to antihistamines and only partially to systemic steroids, but resolved consistently when the thyroxine level was reduced to normal. The mechanism for the association may involve mo...

journal_title：Clinical and experimental dermatology

authors： Henderson CA,Highet AS

更新日期：1995-03-01 00:00:00

abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

journal_title：Clinical and experimental dermatology

authors： English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

更新日期：2011-03-01 00:00:00

abstract：:The high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, plays a central role in the initiation and control of atopic allergic inflammation. On mast cells and basophils, the function of the receptor is well known and constitutes cellular degranulation and the release of various mediators. FcepsilonRI on ant...

journal_title：Clinical and experimental dermatology

authors： von Bubnoff D,Novak N,Kraft S,Bieber T

更新日期：2003-03-01 00:00:00

abstract：:In Europe and the USA, the incidence of primary nasal natural killer (NK)/T-cell lymphoma is rare. The skin is one of the predilection sites for dissemination. Cutaneous dissemination is a poor prognostic sign and is consistently fatal. We describe the case of a 17-year-old white German girl with a primary nasal NK/T-...

journal_title：Clinical and experimental dermatology

authors： Sandner A,Helmbold P,Winkler M,Gattenlöhner S,Müller-Hermelink HK,Holzhausen HJ

更新日期：2008-08-01 00:00:00

abstract：:Extramammary Paget's disease (EMPD) is considered to be an intraepithelial adenocarcinoma. Typically involved anatomical sites are the vulvar, perianal, perineal, scrotal and penile regions. Clinically, the lesions present as well-defined, moist, erythematous plaques usually accompanied by pruritus. An unusual feature...

journal_title：Clinical and experimental dermatology

authors： Pascual JC,Perez-Ramos M,Devesa JP,Kutzner H,Requena L

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Vitamin D has significant effects on the immune system and thereby on the pathogenesis of rosacea. However, there is a lack of information on the vitamin D status and vitamin D receptors (VDRs) of patients with rosacea. AIM:To evaluate the role of vitamin D in rosacea susceptibility. METHODS:A case-control...

journal_title：Clinical and experimental dermatology

authors： Akdogan N,Alli N,Incel Uysal P,Candar T

更新日期：2019-06-01 00:00:00

abstract：:Imiquimod 5% cream has proven to be effective in superficial and nodular basal cell carcinomas in nonimmunosuppressed patients and treating squamous cell carcinomas in situ in transplant patients. The objective of this open-label study was to determine the efficacy of imiquimod 5% cream in treating basal cell carcinom...

journal_title：Clinical and experimental dermatology

authors： Vidal D,Alomar A

更新日期：2004-05-01 00:00:00

abstract：:The clinical characteristics associated with hidradenitis suppurativa (HS) severity are poorly understood. In this study, 124 patients with HS from 6 Italian dermatology centres participated in this study. Disease severity was assessed using the Hidradenitis Suppurativa Physician's Global Assessment score (HS-PGA) and...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Caposiena Caro RD,Ganzetti G,Molinelli E,Dini V,Oranges T,Romanelli M,Fabbrocini G,Monfrecola G,Napolitano M,Egan CG,Musumeci ML,Lacarrubba F,Micali G,Passoni E,Calzavara-Pinton PG,Venturini M,Zanca A,Offida

更新日期：2019-07-01 00:00:00

abstract：:The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...

journal_title：Clinical and experimental dermatology

authors： Jones SK,Handfield-Jones S,Kennedy CT

更新日期：1990-05-01 00:00:00

abstract：:Melanoma-associated retinopathy (MAR) is a rare paraneoplastic autoimmune manifestation of cutaneous malignant melanoma. Patients classically present with acute onset night blindness, positive visual phenomena and visual field defects, and typically have significantly reduced quality of life as a result. Early recogni...

journal_title：Clinical and experimental dermatology

authors： Elsheikh S,Gurney SP,Burdon MA

更新日期：2020-03-01 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：:The case of a 40-year-old man with delusions of parasitosis as the presentation of a monodelusional psychosis is reported. In spite of treatment with pimozide and depot neuroleptics the patient committed suicide. Since the introduction of pimozide, this drug has come to be regarded as the specific treatment for this d...

journal_title：Clinical and experimental dermatology

authors： Monk BE,Rao YJ

更新日期：1994-07-01 00:00:00

abstract：:We report a case of white fibrous papulosis of the neck in a 70-year-old Iranian woman. To date this recently reported entity has only been described in Japanese patients. This asymptomatic eruption characteristically affects the posterior neck. The pale papules are round to oval 2-3 mm in diameter, and not follicular...

journal_title：Clinical and experimental dermatology

authors： Cerio R,Gold S,Jones EW

更新日期：1991-05-01 00:00:00

abstract：:We report the case of a 26-year-old man with haemophilia B and human immunodeficiency virus infection (HIV) who presented with a short history of multiple dermatofibromas. He also had troublesome psoriasis for which he was receiving acitretin with UVB therapy and had recently discontinued low-dose daily prednisolone f...

journal_title：Clinical and experimental dermatology

authors： Armstrong DK,Irvine A,Walsh MY,Mayne EE,Burrows D

更新日期：1995-11-01 00:00:00

abstract：:A 71-year-old woman with vitiligo developed multiple actinic keratoses only on the vitiligo skin of sun-exposed areas. She had worked outdoors as a farmer for a long period. Although actinic skin cancers arising on vitiligo skin have rarely been reported, the present case demonstrates that vitiligo skin is more suscep...

journal_title：Clinical and experimental dermatology

authors： Yashiro K,Nakagawa T,Takaiwa T,Inai M

更新日期：1999-05-01 00:00:00

abstract：:Immunosuppression is recognized to predispose to the development of disseminated superficial actinic porokeratosis and to cause the spread of pre-existing lesions. Porokeratosis of Mibelli has been less frequently described following immunosuppression and we report a further case. ...

journal_title：Clinical and experimental dermatology

authors： Wilkinson SM,Cartwright PH,English JS

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Lichen sclerosus (LS) is a chronic inflammatory dermatosis with a predilection for the anogenital region, which mainly affects prepubertal girls and postmenopausal women. The cause is unknown, but a number of potential aetiological factors have been identified. AIM:To examine a cohort of patients with prepu...

journal_title：Clinical and experimental dermatology

authors： Ismail D,Owen CM

更新日期：2019-10-01 00:00:00

abstract：:Klippel-Trenaunay (KT) syndrome is a vascular malformation characterized by a port-wine stain, varicose veins and hypertrophy of the affected limb. Ulceration is considered an uncommon complication of KT syndrome and occurrence of skin cancer has been previously reported only in one case. We observed a case of KT synd...

journal_title：Clinical and experimental dermatology

authors： De Simone C,Giampetruzzi AR,Guerriero C,De Masi M,Amerio P,Cina G

更新日期：2002-05-01 00:00:00