Sex-related differences of clinical features in hidradenitis suppurativa: analysis of an Italian-based cohort.

Abstract:

:The clinical characteristics associated with hidradenitis suppurativa (HS) severity are poorly understood. In this study, 124 patients with HS from 6 Italian dermatology centres participated in this study. Disease severity was assessed using the Hidradenitis Suppurativa Physician's Global Assessment score (HS-PGA) and Hurley score. The impact of clinical characteristics on disease severity was assessed by logistic regression. Clinical characteristics were similar between men (n = 53) and women (n = 71). Disease severity was also similar; 75% of the patients had Hurley stage II or III disease, and > 60% had moderate, severe or very severe HS as judged by HS-PGA. Lesions were more frequent in the gluteal region in men (32.3% in men vs. 8.7% in women, P < 0.001) and more frequent on the breast in women (16.3% in women vs. 4.6% in men, P = 0.02). Obesity was associated with increased disease severity as measured by HS-PGA (OR: 3.28, 95% CI 1.55-6.95, P < 0.01) and Hurley classification (OR: 3.22, 95% CI 1.34-7.31, P < 0.01). Although severity of HS is similar between the sexes, the localization of lesions is different.

journal_name

Clin Exp Dermatol

authors

Bianchi L,Caposiena Caro RD,Ganzetti G,Molinelli E,Dini V,Oranges T,Romanelli M,Fabbrocini G,Monfrecola G,Napolitano M,Egan CG,Musumeci ML,Lacarrubba F,Micali G,Passoni E,Calzavara-Pinton PG,Venturini M,Zanca A,Offida

doi

10.1111/ced.13861

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

e177-e180

issue

5

eissn

0307-6938

issn

1365-2230

journal_volume

44

pub_type

杂志文章
  • The value of direct immunofluorescence as a diagnostic aid in dermatomyositis--a study of 35 cases.

    abstract::Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:

    authors: Jones SA,Black MM

    更新日期:1997-03-01 00:00:00

  • A new subtype of pachydermodactyly: unilateral pachydermodactyly transgrediens.

    abstract::Pachydermodactyly describes a rare condition of localized fibromatosis, usually symmetrically affecting the interphalangeal joints of both hands. We describe a case of a new subtype of pachydermodactyly in a 14-year-old boy, which we term 'unilateral pachydermodactyly transgrediens'. This atypical pattern is caused by...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12617

    authors: Nicolay JP,Faulhaber J,Kutzner H,Schneider SW

    更新日期:2015-08-01 00:00:00

  • Congenital desmoplastic trichoepithelioma.

    abstract::Desmoplastic trichoepithelioma (DT) is a rare benign adnexal neoplasm considered to have follicular differentiation. It usually presents as an asymptomatic, firm, annular plaque with a raised border. The most common site of occurrence is the face, usually on the cheek. Females are more often affected than males and th...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2007.02431.x

    authors: Carter JJ,Kaur MR,Hargitai B,Brown R,Slator R,Abdullah A

    更新日期:2007-09-01 00:00:00

  • Upregulation of collagen type 1 in aged murine dermis after transplantation of dermal multipotent cells.

    abstract:BACKGROUND:Multipotent cells can be isolated from dermis, and have wound-healing and antioxidant effects on human and murine skin. AIM:To investigate the changes in aged dermis after injection of dermal multipotent cells and adult fibroblasts. METHODS:Dermal multipotent cells were isolated and cultured from 3-day-old...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2011.04071.x

    authors: Xue S,Li L

    更新日期:2011-10-01 00:00:00

  • Cutaneous involvement in an 8-year-old boy with Ras-associated autoimmune leucoproliferative disorder (RALD).

    abstract::Ras-associated autoimmune leucoproliferative disorder (RALD) is a nonmalignant syndrome associated with somatic KRAS mutations. We report a patient with RALD and cutaneous lesions, the first such case reported, to our knowledge. An 8-year-old boy presented with erythematous plaques on his face and body, along with lym...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13668

    authors: Giacaman A,Bauzá Alonso A,Salinas Sanz JA,Dapena Díaz JL,Ramos Asensio R,Ferrés Ramis L,Durán Pastor MA,Martín-Santiago A

    更新日期:2018-12-01 00:00:00

  • Ultrastructural changes of Trichophyton rubrum in tinea unguium after itraconazole therapy in vivo observed using scanning electron microscopy.

    abstract:BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13641

    authors: Yue X,Wang A,Sun Y,Li Q

    更新日期:2018-12-01 00:00:00

  • Repeated episodes of fixed eruption 3 months after discontinuing pegylated interferon-alpha-2b plus ribavirin combination therapy in a patient with chronic hepatitis C virus infection.

    abstract::We report a 73-year-old man who developed repeated episodes of erythematous, bullous plaques beginning 3 months after discontinuation of combination treatment with pegylated interferon (IFN)-alpha-2b and ribavirin for hepatitis C virus infection. The first episode resolved within a week without treatment, but the lesi...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2009.03560.x

    authors: Sato M,Sueki H,Iijima M

    更新日期:2009-12-01 00:00:00

  • Multiple dermatofibromata developing during pregnancy.

    abstract::Dermatofibromata are common benign dermal tumours of unknown aetiology. They usually present as a single lesion on the limbs of young adults. Multiple dermatofibromata have been reported occurring in patients with autoimmune disease, who were receiving immunosuppressive treatment. A 25-year-old female is reported who ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1994.tb01118.x

    authors: Stainforth J,Goodfield MJ

    更新日期:1994-01-01 00:00:00

  • Teledermatology in practice.

    abstract::Teledermatology has been the focus of much interest in recent years. Potential uses include a simple supporting role for primary care, more accurate triage of dermatology patients or an 'advice only' service reducing the need for dermatology patients to attend outpatient clinics. With the current under-provision of de...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2003.01313.x

    authors: Mallett RB

    更新日期:2003-07-01 00:00:00

  • Everyday clinical experience of alitretinoin in the treatment of severe chronic hand eczema: seven case studies.

    abstract::Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2010.04006_1.x

    authors: English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

    更新日期:2011-03-01 00:00:00

  • Follicular porokeratosis of Mibelli on the buttocks.

    abstract::We report a case of follicular porokeratosis of Mibelli affecting the natal cleft in a 42-year-old white man. To our knowledge, this is the first report in the English-language literature of follicular porokeratosis of Mibelli limited to the genitogluteal area. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2230.2008.02879.x

    authors: Yong AS,Singh M,Goulding JM,Swale VJ

    更新日期:2009-01-01 00:00:00

  • Tacalcitol and narrow-band phototherapy in patients with vitiligo.

    abstract:BACKGROUND:Vitiligo is a skin disease characterized by loss of normal pigmentation in the skin. Several treatments exist but none is really effective. Recently, perturbations of calcium homeostasis in vitiliginous epidermis have been described. AIM:Based on these findings, the aim of this prospective, randomized, open...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2230.2005.02037.x

    authors: Leone G,Pacifico A,Iacovelli P,Paro Vidolin A,Picardo M

    更新日期:2006-03-01 00:00:00

  • Isotretinoin-associated pseudoporphyria.

    abstract::We present two patients who developed pseudoporphyria whilst taking isotretinoin (Roaccutane). At that time, both patients were receiving other agents which could be incriminated as causing their pseudoporphyria. However, it is significant that these other agents had been longstanding and that the porphyria-like cutan...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1993.tb00974.x

    authors: Riordan CA,Anstey A,Wojnarowska F

    更新日期:1993-01-01 00:00:00

  • Metallothionein I and II gene knock-out mice exhibit reduced tolerance to 24-h sodium lauryl sulphate patch testing.

    abstract:BACKGROUND:Metallothioneins (MTs) are a group of proteins widely distributed in tissues regulating metal metabolism, scavenging free radicals, and taking part in immunological reactions. Knockout mice for MT genes I and II (MT(-/-)) exhibit reduced tolerance to ultraviolet B injury in vivo. Upregulation of MT proteins ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2007.02399.x

    authors: Ma C,Li LF,Zhang BX

    更新日期:2007-07-01 00:00:00

  • Improvement of trigeminal neurotrophic ulceration with pimozide in a cognitively impaired elderly woman--a case report.

    abstract::Neurotrophic ulceration of the face is a rare but well recognized sequel to division of the trigeminal nerve. Trauma is an important contributory factor and thought to be due in part to paraesthesiae, which encourages picking and scratching, with resultant chronic and persistent ulceration. A case is described of an 8...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1993.tb01007.x

    authors: Mayer RD,Smith NP

    更新日期:1993-03-01 00:00:00

  • Bullous skin reaction seen after extravasation of calcium gluconate.

    abstract::Intravenous (IV) calcium is usually given to temporarily treat the effects of hyperkalaemia on muscle and heart. When extravasation of a calcium gluconate infusion occurs, there may be rapid and marked swelling and erythema, with signs of soft-tissue necrosis or infection, and ensuing extensive local calcification, ca...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2012.04436.x

    authors: Celbek G,Gungor A,Albayrak H,Kir S,Guvenc SC,Aydin Y

    更新日期:2013-03-01 00:00:00

  • Disaccharide analysis of the skin glycosaminoglycans in patients with Werner's syndrome.

    abstract::The disaccharide content of the chondroitinase-digestible glycosaminoglycans (GAGs) extracted from 6-mm skin punch biopsies from the atrophic and sclerotic skin of two patients with Werner's syndrome (WS) were determined using high-performance liquid chromatography after 1-phenyl-3-methyl-5-pyrazolone labelling. The t...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1994.tb01253.x

    authors: Higuchi T,Ishikawa O,Hayashi H,Ohnishi K,Miyachi Y

    更新日期:1994-11-01 00:00:00

  • Liquid chromatography-tandem mass spectrometry is effective for analysis of ergosterol in fungal-infected nails.

    abstract:BACKGROUND:Identification of onychomycosis is mainly based on clinical diagnosis with auxiliary diagnostic methods such as potassium hydroxide (KOH) microscopy, periodic acid-Schiff staining or fungal culture. However, each method is limited by its sensitivity and specificity. AIM:To develop a new test method using th...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13933

    authors: Ho WT,Li Y,Yang S

    更新日期:2019-06-01 00:00:00

  • Neutrophil folliculitis and serum androgen levels.

    abstract::Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy the aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition th...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.1999.00510.x

    authors: Vaughan Jones SA,Hern S,Black MM

    更新日期:1999-09-01 00:00:00

  • Secondary localized cutaneous amyloid in Bowen's disease.

    abstract::A case of Bowen's disease is described in which striking quantities of amyloid were detected in the papillary dermis visualized easily by routine haematoxylin and eosin staining. The material showed positive labelling with an antikeratin monoclonal antibody consistent with the proposed origin of the amyloid as degener...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1993.tb02191.x

    authors: Speight EL,Milne DS,Lawrence CM

    更新日期:1993-05-01 00:00:00

  • Comparative efficacy of drug regimens in skin tuberculosis.

    abstract::Three antituberculous drug regimens have been employed to study the therapeutic response in 90 patients with any one of the commonly encountered paucibacillary forms of skin tuberculosis, namely lupus vulgaris, tuberculosis verrucosa cutis and scrofuloderma. The first two regimens contained rifampicin, isoniazid and e...

    journal_title:Clinical and experimental dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-2230.1991.tb00317.x

    authors: Ramesh V,Misra RS,Saxena U,Mukherjee A

    更新日期:1991-03-01 00:00:00

  • Induction of hair growth in alopecia totalis with diphencyprone sensitization.

    abstract::The therapeutic use of the induction of an allergic contact sensitivity to diphencyprone in alopecia areata has been studied. Fourteen subjects had alopecia totalis and four had extensive and long-standing alopecia areata. Topical diphencyprone was capable of inducing an allergic contact sensitivity in 16 subjects (89...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1989.tb00915.x

    authors: Monk B

    更新日期:1989-03-01 00:00:00

  • Erosive pustular dermatosis of the leg mimicking lower limb cellulitis.

    abstract::Erosive pustular dermatosis (EPD) of the leg is an unusual form of amicrobial pustulosis, which typically affects elderly patients with chronic venous insufficiency. We report a patient who presented with painful erythema, crusted erosions and pustules on her right lower leg. Histology showed a dermal infiltration mad...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12512

    authors: Zhou Z,Zhang ZK,Liu TH

    更新日期:2015-12-01 00:00:00

  • Recombinant human erythropoietin stimulates vasculogenesis and wound healing in a patient with systemic sclerosis complicated by severe skin ulcers.

    abstract::Systemic sclerosis (SSc) is often complicated by severe skin ulcers that are unresponsive to traditional treatments. Vascular alterations are responsible for the ischaemic features of the disease in both the skin and visceral organs. Defective neoangiogenesis correlates with an abnormally reduced quantity of circulati...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2010.03847.x

    authors: Ferri C,Giuggioli D,Manfredi A,Quirici N,Scavullo C,Colaci M,Gianelli U,Deliliers GL,Del Papa N

    更新日期:2010-12-01 00:00:00

  • Folliculosebaceous cystic hamartoma arising within a port-wine stain.

    abstract::A 34-year-old woman presented with 2-year history of a dome-shaped papule on a well-circumscribed, thickened, port-wine stain on the left side of the chin. Squeezing on the port-wine-stain plaque revealed many comedos within dilated follicular orifices. The papule was excised and submitted for histological examination...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2005.01838.x

    authors: Yang CH,Shen SC,Yeh JT,Tsai YL,Hong HS

    更新日期:2005-09-01 00:00:00

  • Specific loss of connexin 26 expression in ductal sweat gland epithelium associated with the deletion mutation del(GJB6-D13S1830).

    abstract::A whole array of cutaneous syndromes is associated with distinct dominant mutations in GJB2 encoding the gap junction protein connexin 26 (C x 26), including Vohwinkel's syndrome and keratitis-ichthyosis-deafness syndrome. In contrast, recessive GJB2 mutations occur in a large proportion of individuals with hearing lo...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2005.01878.x

    authors: Common JE,Bitner-Glindzicz M,O'Toole EA,Barnes MR,Jenkins L,Forge A,Kelsell DP

    更新日期:2005-11-01 00:00:00

  • Giant nerve abscesses in leprosy.

    abstract::Two leprosy patients with neuritis caused by giant abscesses involving almost the entire ulnar nerve are described. One patient, who also had skin lesions, was diagnosed histopathologically as having borderline tuberculoid leprosy both on skin and nerve biopsy, and the other, with only nerve involvement, belonged to t...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1990.tb02110.x

    authors: Saxena U,Ramesh V,Misra RS,Mukherjee A

    更新日期:1990-09-01 00:00:00

  • Cutaneous infection with an Alternaria sp. in an immunocompetent host.

    abstract::We report a case of cutaneous alternariosis in an immunocompetent 85-year-old man. Identification of the causative organism in this patient was achieved by 18S rRNA sequencing. A 6-month course of itraconazole led to a good clinical response. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2007.02664.x

    authors: Williams C,Layton AM,Kerr K,Kibbler C,Barton RC

    更新日期:2008-07-01 00:00:00

  • Serum triamcinolone levels during intensive, inpatient wet-dressing therapy.

    abstract:BACKGROUND:Wet dressings combined with topical corticosteroids are beneficial for patients with generalized and refractory dermatosis; however, to our knowledge, serum levels after topical corticosteroid absorption during intensive therapy have not been reported previously. AIM:To examine serum levels of triamcinolone...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.14161

    authors: Mirza SA,Wentworth AB,Harvey JA,Bridges AG,Camilleri MJ,El-Azhary RA,McEvoy MT,Sartori Valinotti JC,Wetter DA,Davis MDP

    更新日期:2020-07-01 00:00:00

  • Thalidomide-induced toxic pustuloderma.

    abstract::We report a case of toxic pustuloderma secondary to thalidomide in a patient with severe nodular prurigo. To our knowledge this is the first reported case. With the increasing use of thalidomide for a variety of dermatological conditions it is clearly important that this rare side-effect now be recognised. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:

    authors: Darvay A,Basarab T,Russell-Jones R

    更新日期:1997-11-01 00:00:00