Competency assessment of dermatology trainees in the UK.

abstract：:Endogenous ochronosis or alkaptonuria is a rare, autosomal recessive disease of tyrosine metabolism that is caused by a deficiency of the enzyme homogentisic acid oxidase. The disease results in the accumulation and deposition of homogentisic acid in the cartilage, eyelids, forehead, cheeks, axillae, genital region, b...

journal_title：Clinical and experimental dermatology

authors： Turgay E,Canat D,Gurel MS,Yuksel T,Baran MF,Demirkesen C

更新日期：2009-12-01 00:00:00

abstract：:A 72-year-old woman with a 14-year history of urticarial vasculitis (UV) and a 13-year history of bullous pemphigoid (BP) presented with associated progressive chronic lymphocytic leukaemia (CLL). Both skin conditions responded poorly to treatment, until chemotherapy for CLL was commenced. The skin features showed a c...

journal_title：Clinical and experimental dermatology

authors： Kassim JM,Igali L,Levell NJ

更新日期：2015-06-01 00:00:00

abstract：:Desmoplastic trichoepithelioma (DT) is a rare benign adnexal neoplasm considered to have follicular differentiation. It usually presents as an asymptomatic, firm, annular plaque with a raised border. The most common site of occurrence is the face, usually on the cheek. Females are more often affected than males and th...

journal_title：Clinical and experimental dermatology

authors： Carter JJ,Kaur MR,Hargitai B,Brown R,Slator R,Abdullah A

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Cutis marmorata telangiectatica congenita (CMTC) is a congenital vascular anomaly of unknown aetiology. About 300 cases have been reported in the literature. The rate of associated anomalies varies between 20% and 70%. METHODS:We report a series of 27 children with CMTC, 18 of whom were followed-up prospect...

journal_title：Clinical and experimental dermatology

authors： Kienast AK,Hoeger PH

更新日期：2009-04-01 00:00:00

abstract：:The effect of dietary supplementation with a combination of n-3 (marine oil) and n-6 (evening primrose oil) essential fatty acids in the treatment of chronic stable plaque psoriasis was observed. Thirty-seven patients in a double-blind parallel trial were studied. There was no significant improvement in clinical sever...

journal_title：Clinical and experimental dermatology

authors： Oliwiecki S,Burton JL

更新日期：1994-03-01 00:00:00

abstract：:Fourteen patients with psoriasis received long-term treatment with cyclosporin (CsA). Among patients there was great variability in the minimal effective CsA dose. In most patients long-term treatment was limited due to dose reductions made necessary because of side-effects. The therapeutic window for CsA seems small....

journal_title：Clinical and experimental dermatology

authors： Korstanje MJ,Van de Staak WJ

更新日期：1991-01-01 00:00:00

abstract：:The case of an 80-year-old woman who developed extensive cutaneous calcification following intravenous phosphate administration is presented. Also the circumstances under which cutaneous calcification may occur are discussed. ...

journal_title：Clinical and experimental dermatology

authors： Mills CM,Knight AG

更新日期：1993-07-01 00:00:00

abstract：:The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site (face, dorsal right forearm and han...

journal_title：Clinical and experimental dermatology

authors： Green C,Orchard G,Cerio R,Hawk JL

更新日期：1998-07-01 00:00:00

abstract：:Rapp-Hodgkin syndrome (RHS) is an autosomal dominant disorder characterized by ectodermal dysplasia and cleft lip/cleft palate. Very recently, mutations in p63 have been identified as a cause of RHS; to date five such mutations have been identified. We describe a Thai girl with RHS. She had short stature, ectodermal d...

journal_title：Clinical and experimental dermatology

authors： Shotelersuk V,Janklat S,Siriwan P,Tongkobpetch S

更新日期：2005-05-01 00:00:00

abstract：:Langerhans cells at the site of patch tests to inhaled allergens in patients with atopic dermatitis were investigated. Within 24 h the Langerhans cells showed increased cellular activity and became apposed to mononuclear cells. This supports the view that Langerhans cells are involved in antigen presentation in atopic...

journal_title：Clinical and experimental dermatology

authors： Najem N,Hull D

更新日期：1989-05-01 00:00:00

abstract：:Although many antihistamines are now in clinical use, few studies directly compare their pharmacodynamic and sedative activities in humans in vivo. We designed a double-blind, placebo-controlled, crossover study to compare the inhibitory effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-in...

journal_title：Clinical and experimental dermatology

authors： Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2004-09-01 00:00:00

abstract：:Two leprosy patients with neuritis caused by giant abscesses involving almost the entire ulnar nerve are described. One patient, who also had skin lesions, was diagnosed histopathologically as having borderline tuberculoid leprosy both on skin and nerve biopsy, and the other, with only nerve involvement, belonged to t...

journal_title：Clinical and experimental dermatology

authors： Saxena U,Ramesh V,Misra RS,Mukherjee A

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The hyperactive melanocytes present in melasma skin are confined to the epidermis, but epidermal ablation to treat melasma pigmentation may lead to disease recurrence and aggravation. Melanocyte function is regulated by interactions between melanocytes and neighbouring cells such as keratinocytes and fibrobl...

journal_title：Clinical and experimental dermatology

authors： Byun JW,Park IS,Choi GS,Shin J

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Vitiligo is a skin disease characterized by loss of normal pigmentation in the skin. Several treatments exist but none is really effective. Recently, perturbations of calcium homeostasis in vitiliginous epidermis have been described. AIM:Based on these findings, the aim of this prospective, randomized, open...

journal_title：Clinical and experimental dermatology

authors： Leone G,Pacifico A,Iacovelli P,Paro Vidolin A,Picardo M

更新日期：2006-03-01 00:00:00

abstract：:It is only in the past 10 years that the allergenic potential of topical corticosteroids has been fully realized. This has an important impact on the management of patients with chronic eczematous eruptions. Nonhalogenated topical steroids are more frequent sensitizers than halogenated molecules. Tixocortol pivalate a...

journal_title：Clinical and experimental dermatology

authors： English JS

更新日期：2000-06-01 00:00:00

abstract：:Twenty-six men who presented with male pattern baldness (androgen-dependent alopecia), were quantitatively evaluated for scalp hair variables and compared with 13 age-matched controls. Compared to controls, significant mean differences for hair variables were found in the frontal-vertex area, while in the occipital ar...

journal_title：Clinical and experimental dermatology

authors： Rushton DH,Ramsay ID,Norris MJ,Gilkes JJ

更新日期：1991-05-01 00:00:00

abstract：:We report a case of toxic pustuloderma secondary to thalidomide in a patient with severe nodular prurigo. To our knowledge this is the first reported case. With the increasing use of thalidomide for a variety of dermatological conditions it is clearly important that this rare side-effect now be recognised. ...

journal_title：Clinical and experimental dermatology

authors： Darvay A,Basarab T,Russell-Jones R

更新日期：1997-11-01 00:00:00

abstract：:The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...

journal_title：Clinical and experimental dermatology

authors： Jones SK,Handfield-Jones S,Kennedy CT

更新日期：1990-05-01 00:00:00

abstract：:We report the case of a 43-year-old woman, a longstanding heavy cigarette smoker, who developed Bürger's disease, leading to mid-thigh amputation of her left leg. After she gave up smoking her disease was arrested but Raynaud's phenomenon continues to affect her hands and right foot. In reviewing the literature, we fo...

journal_title：Clinical and experimental dermatology

authors： Abdullah AN,Keczkes K

更新日期：1990-01-01 00:00:00

abstract：:Although Q-switched (QS) lasers are the mainstay of modern tattoo removal, paradoxical darkening of tattoo ink may occur. This darkening of tattoo ink is dependent on laser wavelength, pulse duration and fluence, with high-energy, nanosecond-pulsed lasers more prone to induce tattoo-ink darkening. Laser toning, consis...

journal_title：Clinical and experimental dermatology

authors： Chung WK,Yang JH,Lee DW,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is characterized by lymphocytic infiltrate, fibrosis and potential destruction of the hair follicle. Demographic and clinical studies in LPP are limited, and racial differences have not been thoroughly investigated. AIM:To analyse epidemiological data and clinical profiles of Chile...

journal_title：Clinical and experimental dermatology

authors： Mardones F,Shapiro J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The protein kynureninase (KYNU) has recently been reported to participate in the pathological processes of various diseases. AIM:To explore the expression and the biological function of KYNU in cutaneous squamous cell carcinoma (cSCC). METHODS:Expression of KYNU in cSCC cell lines and tissues was firstly e...

journal_title：Clinical and experimental dermatology

authors： Ci C,Wu C,Lyu D,Chang X,He C,Liu W,Chen L,Ding W

更新日期：2020-03-01 00:00:00

abstract：:Teledermatology has been the focus of much interest in recent years. Potential uses include a simple supporting role for primary care, more accurate triage of dermatology patients or an 'advice only' service reducing the need for dermatology patients to attend outpatient clinics. With the current under-provision of de...

journal_title：Clinical and experimental dermatology

authors： Mallett RB

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (HHV) reactivation. The diagnosis of DIHS is ba...

journal_title：Clinical and experimental dermatology

authors： Teraki Y,Shibuya M,Izaki S

更新日期：2010-10-01 00:00:00

abstract：:Pemphigus vulgaris (PV) is an autoimmune bullous disease characterized by autoantibodies against desmogleins. We report a case of recalcitrant PV, which progressed from the mucosal to the mucocutaneous type, with a corresponding increase in anti-desmoglein (Dsg)1 and decrease in anti-Dsg3 antibody titres. Thus, the cl...

journal_title：Clinical and experimental dermatology

authors： Fujii M,Honma M,Iinuma S,Kaneta K,Komatsu S,Sato K,Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2011-04-01 00:00:00

abstract：:The use of an aqueous solution of 0.5% topical glycopyrollate was effective in the treatment of hyperhidrosis of the scalp and forehead after other treatments had proved ineffective; this appears to be the first report of its use in this condition. ...

journal_title：Clinical and experimental dermatology

authors： Seukeran DC,Highet AS

更新日期：1998-09-01 00:00:00

abstract：:The use of cyclosporin A (CSA) for the treatment of severe psoriasis is well established. However its use is limited by its adverse effects, especially nephrotoxicity. We reviewed 28 patients treated with CSA for severe psoriasis over an 11-year period. All patients were on long-term CSA treatment (median duration 55....

journal_title：Clinical and experimental dermatology

authors： Markham T,Watson A,Rogers S

更新日期：2002-03-01 00:00:00

abstract：:A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...

journal_title：Clinical and experimental dermatology

authors： Archer CB,Elias PM,Lowe NJ,Griffiths WA

更新日期：1989-07-01 00:00:00

abstract：:An earlier standard syphilology textbook states that 'If vesicles are an essential part of an eruption in an adult, the lesions are not due to secondary syphilis'. However, vesicular and bullous eruptions do occur in congenital syphilis and rare reports of both vesicular and pustular eruptions in adults with secondary...

journal_title：Clinical and experimental dermatology

authors： Lawrence P,Saxe N

更新日期：1992-01-01 00:00:00

abstract：:The therapeutic use of the induction of an allergic contact sensitivity to diphencyprone in alopecia areata has been studied. Fourteen subjects had alopecia totalis and four had extensive and long-standing alopecia areata. Topical diphencyprone was capable of inducing an allergic contact sensitivity in 16 subjects (89...

journal_title：Clinical and experimental dermatology

authors： Monk B

更新日期：1989-03-01 00:00:00