Cutaneous calcinosis--an unusual complication of intravenous phosphate administration.

abstract：:Pemphigus vulgaris (PV) is an autoimmune bullous disease characterized by autoantibodies against desmogleins. We report a case of recalcitrant PV, which progressed from the mucosal to the mucocutaneous type, with a corresponding increase in anti-desmoglein (Dsg)1 and decrease in anti-Dsg3 antibody titres. Thus, the cl...

journal_title：Clinical and experimental dermatology

authors： Fujii M,Honma M,Iinuma S,Kaneta K,Komatsu S,Sato K,Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2011-04-01 00:00:00

abstract：:Porphyria cutanea tarda (PCT) is believed to be associated with reduced hepatic uroporphyrinogen decarboxylase activity and risk factors such as alcohol abuse and medication with oral contraceptives and certain other drugs. Recently it has been suggested that hepatitis C virus (HCV) infection may also be associated wi...

journal_title：Clinical and experimental dermatology

authors： Hussain I,Hepburn NC,Jones A,O'Rourke K,Hayes PC

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species (ROS) contribute to the cell dysfunction and tissue damage that result from glucolipotoxicity in diabetes. ROS formation in cells causes oxidative stress, thereby activating oxidative damage-inducing genes. Nuclear factor erythroid 2-related factor 2 (Nrf2) has been shown to play an e...

journal_title：Clinical and experimental dermatology

authors： Lee YJ,Kwon SB,An JM,Kim CH,Lee SH,Choi CY,Nam DH,Park JW,Nam HS,Lee SH,Lee MW,Cho MK

更新日期：2015-03-01 00:00:00

abstract：:We report a case of drug reaction with eosinophilia and systemic symptoms (DRESS) to efalizumab. A 52-year-old man developed a widespread papulovesicular rash after 4 weeks of treatment with efalizumab (1.0 mg/kg/week) for treatment-resistant severe psoriasis. Histology revealed a subepidermal blister with eosinophil-...

journal_title：Clinical and experimental dermatology

authors： White JM,Smith CH,Robson A,Ash G,Barker JN

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Recently, increased evidence has shown that serum micro (mi)RNA levels are a useful biomarker for the diagnosis, prognosis and therapeutic value of various diseases. However, serum miRNA has not been investigated in patients with systemic sclerosis (SSc), to our knowledge. AIM:To investigate the possibility...

journal_title：Clinical and experimental dermatology

authors： Makino K,Jinnin M,Kajihara I,Honda N,Sakai K,Masuguchi S,Fukushima S,Inoue Y,Ihn H

更新日期：2012-01-01 00:00:00

abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

journal_title：Clinical and experimental dermatology

authors： English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

更新日期：2011-03-01 00:00:00

abstract：:Sweet's syndrome (acute febrile neutrophilic dermatosis, SS) may be considered a reactional dermatosis with numerous associated diseases. We describe a rare association between SS and acute sarcoidosis in a 55-year-old woman. The atypical feature of positive tuberculin reaction is discussed. In this association, diagn...

journal_title：Clinical and experimental dermatology

authors： Dadban A,Hirschi S,Sanchez M,Lagrange B

更新日期：2009-03-01 00:00:00

abstract：:Two men, aged in their 20s, presented with multiple, soft, rounded papules on the prepuce. The lesions were centrally umbilicated, resembling molluscum contagiosum, but clearly distinct from Tyson's glands. Surface microscopy showed well-defined, milky-white, bag-shaped structures, which under histological examination...

journal_title：Clinical and experimental dermatology

authors： Ena P,Origa D,Massarelli G

更新日期：2009-04-01 00:00:00

abstract：:The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...

journal_title：Clinical and experimental dermatology

authors： Jones SK,Handfield-Jones S,Kennedy CT

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Recently, a new population of IL-17-producing CD4 T helper (Th) cells, named Th17, was identified and shown to be involved in various inflammatory and autoimmune diseases, including psoriasis. AIM:To determine the frequency of Th17 cells and related cytokines in peripheral blood of patients with psoriasis, ...

journal_title：Clinical and experimental dermatology

authors： Chhabra S,Narang T,Joshi N,Goel S,Sawatkar G,Saikia B,Dogra S,Bansal F,Minz R

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is characterized by lymphocytic infiltrate, fibrosis and potential destruction of the hair follicle. Demographic and clinical studies in LPP are limited, and racial differences have not been thoroughly investigated. AIM:To analyse epidemiological data and clinical profiles of Chile...

journal_title：Clinical and experimental dermatology

authors： Mardones F,Shapiro J

更新日期：2017-10-01 00:00:00

abstract：:Incipient osteomalacia developed in a Pakistani patient living in the UK after strict sunlight avoidance forming part of the management of the photosensitivity disorder, chronic actinic dermatitis. The patient's skin type and diet, which included calcium-binding phytates in chappattis, had increased his risk of the co...

journal_title：Clinical and experimental dermatology

authors： Kapur N,Creamer D,Hawk J

更新日期：2000-07-01 00:00:00

abstract：:Humans are the natural host for eight of more than 80 known herpes viruses. Infections with herpes simplex virus type 1 (HSV-1) are ubiquitous worldwide and highly transmissible. Herpes simplex labialis (HSL) is the best-recognized recrudescent infection of the lips and perioral tissues caused by HSV-1. Facial lesions...

journal_title：Clinical and experimental dermatology

authors： Fatahzadeh M,Schwartz RA

更新日期：2007-11-01 00:00:00

abstract：:Sensitive skin (SS) is a widespread condition, but still not completely understood. To identify risk factors that increase the likelihood of SS, 258 women aged between 20 and 65 years old and resident in the Netherlands were surveyed by questionnaire, which included questions on sociodemographic characteristics (age g...

journal_title：Clinical and experimental dermatology

authors： Falcone D,Richters RJH,Uzunbajakava NE,van Erp PEJ,van de Kerkhof PCM

更新日期：2017-08-01 00:00:00

abstract：:Guadeloupe is a French Caribbean island, with a population of mainly African ancestry, and a high standard of living. We recorded the dermatological diagnoses in 5000 new patients attending dermatologists. The main diagnoses were acne (16.4%), superficial mycoses (12.8%), and eczema (10.5%). Diseases considered to be ...

journal_title：Clinical and experimental dermatology

authors： Mahé A,Mancel E

更新日期：1999-09-01 00:00:00

abstract：:A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...

journal_title：Clinical and experimental dermatology

authors： Happle R

更新日期：2009-10-01 00:00:00

abstract：:We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with pr...

journal_title：Clinical and experimental dermatology

authors： Perez A,Clements SE,Benton E,Robson A,Bhogal B,Stefanato CM,McGibbon D

更新日期：2009-12-01 00:00:00

abstract：:Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences. We report a case of isoniazid-induced pellagra which occurred despite pyridoxine supplementation. Drug withdrawal and supplementation with niacin led to a rapid...

journal_title：Clinical and experimental dermatology

authors： Darvay A,Basarab T,McGregor JM,Russell-Jones R

更新日期：1999-05-01 00:00:00

abstract：:Lipoid proteinosis is an autosomal recessive condition associated with variable scarring and infiltration of skin and mucosae. The disorder has recently been shown to result from loss-of-function mutations in the extracellular matrix protein 1 gene (ECM1) on 1q21. Extracellular matrix protein 1 has important physiolog...

journal_title：Clinical and experimental dermatology

authors： Chan I,El-Zurghany A,Zendah B,Benghazil M,Oyama N,Hamada T,McGrath JA

更新日期：2003-09-01 00:00:00

abstract：:Human papillomavirus (HPV) is the most common sexually transmitted disorder in young, sexually active populations in the USA and Europe. Giant condyloma acuminatum (GCA) is a unique variant of condyloma acuminata, characterized by local aggressive behaviour despite benign histology. It carries a substantial risk of sq...

journal_title：Clinical and experimental dermatology

authors： Erkek E,Basar H,Bozdogan O,Emeksiz MC

更新日期：2009-04-01 00:00:00

abstract：:Japan is currently experiencing many outbreaks of scabies, occurring mainly in long-term care facilities. Scabies burrows, the only pathognomonic lesion for scabies, often occur on the creases of the palms, and are followed by a pattern of scale reminiscent of the 'wake' left on the surface of water by a moving bird o...

journal_title：Clinical and experimental dermatology

authors： Yoshizumi J,Harada T

更新日期：2009-08-01 00:00:00

abstract：:We report the case of a 28-year-old homosexual man with advanced HIV disease (CDC classification group IV A) who developed erythrodermic psoriasis which responded to calcipotriol, a topical vitamin D analogue. We believe this to be the first reported case of HIV-related psoriasis responsive to this form of treatment. ...

journal_title：Clinical and experimental dermatology

authors： Gray JD,Bottomley W,Layton AM,Cotterill JA,Monteiro E

更新日期：1992-09-01 00:00:00

abstract：:It is a common experience that many Spitz naevi deviate from the idealized or stereotypical representation found in the literature, often causing considerable difficulties in distinguishing them from melanoma. The diagnostic term 'atypical Spitz naevus' is used to describe lesions that deviate from the typical appeara...

journal_title：Clinical and experimental dermatology

authors： de Giorgi V,Sestini S,Massi D,Papi F,Lotti T

更新日期：2008-05-01 00:00:00

abstract：:Knowledge of the physiology of wound healing, in particular the recovery of the dermal and epidermal compartments and the co-ordination of these processes by the cytokine network, is of great importance to rational wound management. The individual components of the wound healing process have been studied using various...

journal_title：Clinical and experimental dermatology

authors： Van de Kerkhof PC,Van Bergen B,Spruijt K,Kuiper JP

更新日期：1994-09-01 00:00:00

abstract：:Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder that causes defects in the DNA repair system. It is characterized by a marked sensitivity to sunlight, and sufferers develop serious sunburns with onset of poikilodermia in the light-exposed skin. Squamous cell carcinomas, basal cell carcinomas (BCCs) a...

journal_title：Clinical and experimental dermatology

authors： Roseeuw D

更新日期：2003-11-01 00:00:00

abstract：:We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one pat...

journal_title：Clinical and experimental dermatology

authors： Jacyk K,Smith A

更新日期：1990-09-01 00:00:00

abstract：:A lighter or whiter complexion is socially desirable in many cultures. This has led to an unregulated and highly profitable market in skin-lightening creams that are readily available over the counter or on the internet. Plant extracts and newer tyrosinase inhibitors such as kojic acid or its derivative kojic dipalmit...

journal_title：Clinical and experimental dermatology

authors： Madhogaria S,Ahmed I

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Lichen planus (LP) is an inflammatory disease of the skin and mucous membranes. Autoimmunity has been suggested as a possible cause of this disease. The cyclooxygenase enzymes (COX-1, COX-2) are the key enzymes in the conversion of arachidonic acid into prostaglandins. Prostaglandin E2 (PGE2), a key product ...

journal_title：Clinical and experimental dermatology

authors： El-Rifaie AA,Rashed LA,Doss RW

更新日期：2015-12-01 00:00:00

abstract：:Multiple dermatofibromas (DFs) are rare and have been thought to be associated with altered immunity. In this report, we describe a 27-year-old Japanese woman with systemic lupus erythematosus (SLE) and Sjögren's syndrome in whom eight nodules appeared over a period of 4 years. Histopathological findings were consiste...

journal_title：Clinical and experimental dermatology

authors： Tsunemi Y,Tada Y,Saeki H,Ihn H,Tamaki K

更新日期：2004-09-01 00:00:00

abstract：:A 55-year-old diabetic female treated with a combination of a short- and intermediate-acting insulin, developed sterile furunculoid lesions at the injection sites which eventually healed with atrophic scars. Histopathologically, an initial neutrophilic stage was followed by granulomatous and fibrotic stages. It was co...

journal_title：Clinical and experimental dermatology

authors： Jordaan HF,Sandler M

更新日期：1989-05-01 00:00:00