The treatment of basal skin carcinomas in two sisters with xeroderma pigmentosum.

abstract：:We report a man with a 3-year-history of a striking eruption of small, 2-3 mm diameter keratotic, crateriform papules distributed symmetrically over the lower limbs. Morphologically the individual papules closely resembled those described in acrokeratoelastoidosis (AK) of Costa and in focal acral hyperkeratosis of Dow...

journal_title：Clinical and experimental dermatology

authors： Helbling I,Tucker SC,Chalmers RJ

更新日期：2001-05-01 00:00:00

abstract：:Azathioprine is used in a variety of dermatological conditions. However, because of its side-effect profile, azathioprine is limited for use in patients with severe disease. An unpredictable, rare and potentially fatal side-effect of azathioprine is the development of a hypersensitivity reaction, often consisting of f...

journal_title：Clinical and experimental dermatology

authors： Knowles SR,Gupta AK,Shear NH,Sauder D

更新日期：1995-07-01 00:00:00

abstract：:Sarcoidosis is a rare disease among children, manifesting differently in children below and above 4-5 years of age. Although the exact incidence and prevalence of childhood sarcoidosis is not known, the cutaneous involvement is frequent in both children and adults. Infiltration of old cutaneous scars with sarcoid gran...

journal_title：Clinical and experimental dermatology

authors： Singal A,Thami GP,Goraya JS

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Lichen sclerosus (LS) is a chronic inflammatory dermatosis with a predilection for the anogenital region, which mainly affects prepubertal girls and postmenopausal women. The cause is unknown, but a number of potential aetiological factors have been identified. AIM:To examine a cohort of patients with prepu...

journal_title：Clinical and experimental dermatology

authors： Ismail D,Owen CM

更新日期：2019-10-01 00:00:00

abstract：:Actinic prurigo (AP) has been found to be strongly associated with HLA DR4 and in particular with the DR4 subtype DRB1*0407. However, AP may occur in the absence of HLA-DR4. Furthermore, it has been shown that HLA-DR4 and DRB1*0407, even in association with polymorphic light eruption (PLE), are insufficient for the ex...

journal_title：Clinical and experimental dermatology

authors： Grabczynska SA,Carey BS,McGregor JM,Hawk JL,Vaughan RW

更新日期：2001-11-01 00:00:00

abstract：:Determining the risk of progression to systemic lupus erythematosus (SLE) among patients diagnosed with discoid lupus erythematosus (DLE), and the time frame of this risk, are important clinical questions. Past reports have demonstrated a wide time frame of progression from DLE to SLE, with mean time to progression of...

journal_title：Clinical and experimental dermatology

authors： Elman SA,Joyce C,Costenbader KH,Merola JF

更新日期：2020-01-01 00:00:00

abstract：:This paper reports a unique case of coexistence of vitiligo vulgaris, lichen planus and psoriasis vulgaris in a 53-year-old man. Five years after the onset of vitiligo, lichen planus developed on his lower lip. Another 4 years after the onset of lichen planus, he also exhibited psoriasis on his upper arms and trunk. B...

journal_title：Clinical and experimental dermatology

authors： Ujiie H,Sawamura D,Shimizu H

更新日期：2006-05-01 00:00:00

abstract：:Paraneoplastic pemphigus (PNP) is an autoimmune blistering disease associated with neoplasms, typically lymphoproliferative disorders. PNP is characterized clinically by painful erosive stomatitis and polymorphous skin lesions. Histopathological findings are also very varied, and include lichen planus-like and pemphig...

journal_title：Clinical and experimental dermatology

authors： Gallo E,García-Martín P,Fraga J,Teye K,Koga H,Hashimoto T,García-Diez A

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM:To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS:The medical records of all the patients with p...

journal_title：Clinical and experimental dermatology

authors： Qiu Y,Ma G,Yang J,Hu X,Chen H,Jin Y,Lin X

更新日期：2013-12-01 00:00:00

abstract：:Polymorphisms of the IL-10 promoter have been implicated in the genetic susceptibility to many autoimmune diseases, including psoriasis. Four putative functional single-nucleotide polymorphisms (SNPs) within the interleukin-10 promoter region (-3575T/A, -2763A/C, -1082G/A and -592C/A) were analysed in 139 patients wit...

journal_title：Clinical and experimental dermatology

authors： Wongpiyabovorn J,Hirankarn N,Ruchusatsawat K,Yooyongsatit S,Asawanonda P,Poovorawan Y

更新日期：2008-03-01 00:00:00

abstract：:It is only in the past 10 years that the allergenic potential of topical corticosteroids has been fully realized. This has an important impact on the management of patients with chronic eczematous eruptions. Nonhalogenated topical steroids are more frequent sensitizers than halogenated molecules. Tixocortol pivalate a...

journal_title：Clinical and experimental dermatology

authors： English JS

更新日期：2000-06-01 00:00:00

abstract：:Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

journal_title：Clinical and experimental dermatology

authors： Jones SA,Black MM

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Effective treatment options for morphoea remain limited. As a result, there has been increasing interest in the role of phototherapy in the management of this condition. Aims. We report the findings of a study in which 13 patients with localized morphoea were treated with oral (n = 11) and topical (n = 2) ps...

journal_title：Clinical and experimental dermatology

authors： Usmani N,Murphy A,Veale D,Goulden V,Goodfield M

更新日期：2008-11-01 00:00:00

abstract：:Secukinumab is an interleukin (IL)-17 monoclonal antibody inhibiting T-helper (Th)1-mediated immune response. It has proven high efficacy for moderate to severe psoriasis but data on its long-term toxicities are limited. We describe two patients who received secukinumab for clinically presumed psoriasis, but were subs...

journal_title：Clinical and experimental dermatology

authors： Yoo J,Shah F,Velangi S,Stewart G,Scarisbrick JS

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin carcinoma. AIM:To investigate the function of key micro(mi)RNAs and to explore the potential molecular mechanisms involved in BCC. METHODS:The microarray dataset GSE34535, which comprises seven BCC samples and seven control samples, was downloaded ...

journal_title：Clinical and experimental dermatology

authors： Mi X,Lai K,Yan L,Xie S,Qiu X,Xiao S,Wei S

更新日期：2020-12-01 00:00:00

abstract：:Recent studies have shown that the protein MIA (melanoma inhibitory activity) is a potent serum marker for malignant melanoma. MIA is expressed in chondrocytes at high levels, and might potentially be elevated during periods of growth in childhood. Therefore, we evaluated MIA serum levels in pregnant women and in grow...

journal_title：Clinical and experimental dermatology

authors： Bosserhoff AK,Küster H,Hein R

更新日期：2004-11-01 00:00:00

abstract：:Imprinting is the process whereby genetic alleles responsible for a phenotype are derived from one parent only. It is an epigenetic phenomenon resulting from DNA methylation or modification of protruding histones. When imprinted genes are disrupted, syndromes with characteristic patterns of inheritance and multisystem...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-09-01 00:00:00

abstract：:The primary cause of collagen degeneration in necrobiosis lipoidica (NL) is proposed to be immunologically mediated vascular disease. Ultraviolet (UV)A1 has been used successfully to treat scleroderma in which both vascular damage and collagen dysregulation also occur. We treated six patients with NL [(five women; mea...

journal_title：Clinical and experimental dermatology

authors： Beattie PE,Dawe RS,Ibbotson SH,Ferguson J

更新日期：2006-03-01 00:00:00

abstract：:Down's syndrome (DS) is associated with rare dermatological disorders and increased frequency of some common dermatoses. Owing to advances in medical care and changes in attitude, the median age of death in this population has increased to 49 years, and the life expectancy of a 1-year-old person with DS today is more ...

journal_title：Clinical and experimental dermatology

authors： Madan V,Williams J,Lear JT

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：:Photo-damage of the head and neck was assessed, by visual inspection, in 82 Northern European renal transplant recipients attending a dermatology clinic. Photo-damage was graded as absent, mild, moderate and severe and the presence or absence of skin telangiectasia, solar elastosis, erythema and pigmentation was asses...

journal_title：Clinical and experimental dermatology

authors： Cooper SM,Wojnarowska F

更新日期：2003-11-01 00:00:00

abstract：:We describe an 18-year-old girl with systemic lupus erythematosus (SLE) who had cutaneous papulonodular mucinosis (PNM) as the first sign of SLE. She presented with multiple flesh-coloured papules on the face, abdomen and limbs. Histological examination of a biopsy taken from a papule showed diffuse deposition of muci...

journal_title：Clinical and experimental dermatology

authors： Shekari AM,Ghiasi M,Ghasemi E,Kani ZA

更新日期：2009-12-01 00:00:00

abstract：:We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

journal_title：Clinical and experimental dermatology

authors： Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

journal_title：Clinical and experimental dermatology

authors： Yue X,Wang A,Sun Y,Li Q

更新日期：2018-12-01 00:00:00

abstract：:Dapsone has potent anti-inflammatory effects, and is used in the treatment of leprosy, cutaneous vasculitis, neutrophilic dermatoses, and dermatitis herpetiformis and other blistering disorders. However, it may cause severe adverse reactions such as hypersensitivity syndrome, which is characterized by fever, skin rash...

journal_title：Clinical and experimental dermatology

authors： Chun JS,Yun SJ,Kim SJ,Lee SC,Won YH,Lee JB

更新日期：2009-12-01 00:00:00

abstract：:Majocchi's granuloma, also known as nodular granulomatous perifolliculitis, is an uncommon fungal infection of the skin and subcutaneous tissue. It can occur in healthy and immunocompromised patients. The most common cause of Majocchi's granuloma is Trichophyton rubrum. We report a case of a Majocchi's granuloma cause...

journal_title：Clinical and experimental dermatology

authors： Saadat P,Kappel S,Young S,Abrishami M,Vadmal MS

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Recently, increased evidence has shown that serum micro (mi)RNA levels are a useful biomarker for the diagnosis, prognosis and therapeutic value of various diseases. However, serum miRNA has not been investigated in patients with systemic sclerosis (SSc), to our knowledge. AIM:To investigate the possibility...

journal_title：Clinical and experimental dermatology

authors： Makino K,Jinnin M,Kajihara I,Honda N,Sakai K,Masuguchi S,Fukushima S,Inoue Y,Ihn H

更新日期：2012-01-01 00:00:00

abstract：:Stewart-Bluefarb syndrome (SBS) is a subtype of pseudo-Kaposi sarcoma (PKS), which is associated with congenital arteriovenous malformation. It is a rare syndrome, characterized by cutaneous lesions with onset in the second decade of life. We report a case of SBS in a 33-year-old man presenting with a 15-year history ...

journal_title：Clinical and experimental dermatology

authors： Verma SB,Vasani R

更新日期：2016-07-01 00:00:00

abstract：:Dermanyssus gallinae is a mite that normally parasitizes small birds but may occasionally bite humans. We report an unusual case of an 82-year-old woman who presented with pruritus and bite-like lesions over her trunk. Other members of the household were also affected. On physical examination, mites < 1 mm in size wer...

journal_title：Clinical and experimental dermatology

authors： Collgros H,Iglesias-Sancho M,Aldunce MJ,Expósito-Serrano V,Fischer C,Lamas N,Umbert-Millet P

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:This is the first study investigating scabies treatment since 1992 to involve examination of patients with microscopically confirmed scabies. AIM:To assess the efficacy of 1% lindane cream in treating microscopically confirmed scabies, and to determine the utility of dermoscopy-guided skin scraping with mic...

journal_title：Clinical and experimental dermatology

authors： Park SE,Her Y,Kim SS,Kim CW

更新日期：2015-08-01 00:00:00