The value of direct immunofluorescence as a diagnostic aid in dermatomyositis--a study of 35 cases.

abstract：:A whole array of cutaneous syndromes is associated with distinct dominant mutations in GJB2 encoding the gap junction protein connexin 26 (C x 26), including Vohwinkel's syndrome and keratitis-ichthyosis-deafness syndrome. In contrast, recessive GJB2 mutations occur in a large proportion of individuals with hearing lo...

journal_title：Clinical and experimental dermatology

authors： Common JE,Bitner-Glindzicz M,O'Toole EA,Barnes MR,Jenkins L,Forge A,Kelsell DP

更新日期：2005-11-01 00:00:00

abstract：:Dermatofibromata are common benign dermal tumours of unknown aetiology. They usually present as a single lesion on the limbs of young adults. Multiple dermatofibromata have been reported occurring in patients with autoimmune disease, who were receiving immunosuppressive treatment. A 25-year-old female is reported who ...

journal_title：Clinical and experimental dermatology

authors： Stainforth J,Goodfield MJ

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). AIM:To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. METHODS:In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched ...

journal_title：Clinical and experimental dermatology

authors： Ucuz I,Altunisik N,Sener S,Turkmen D,Kavuran NA,Marsak M,Colak C

更新日期：2020-02-16 00:00:00

abstract：:Identification of mutations in the hairless (HR) gene in patients with atrichia with papular lesions (APL) has proven of critical importance, as it provides a basis for the differentiation between APL and alopecia universalis. The establishment of the diagnostic criteria for APL has triggered the identification of a l...

journal_title：Clinical and experimental dermatology

authors： Massé M,Martinez-Mir A,Lam H,Geraghty MT,Christiano AM

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM:To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS:The medical records of all the patients with p...

journal_title：Clinical and experimental dermatology

authors： Qiu Y,Ma G,Yang J,Hu X,Chen H,Jin Y,Lin X

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Momordica charantia (MC; bitter gourd) is a traditional herb commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. It is also used for the rapid healing of wounds. AIM:To observe the topical effect of MC extract on the wound-healing process in rats with diabetes induce...

journal_title：Clinical and experimental dermatology

authors： Teoh SL,Latiff AA,Das S

更新日期：2009-10-01 00:00:00

abstract：:Imiquimod 5% cream has proven to be effective in superficial and nodular basal cell carcinomas in nonimmunosuppressed patients and treating squamous cell carcinomas in situ in transplant patients. The objective of this open-label study was to determine the efficacy of imiquimod 5% cream in treating basal cell carcinom...

journal_title：Clinical and experimental dermatology

authors： Vidal D,Alomar A

更新日期：2004-05-01 00:00:00

abstract：:Four patients presenting with chronic pigmented purpuric dermatosis (CPPD) on the limbs were found to have granulomatous inflammation superimposed on the pathological changes of CPPD. Three of the four patients had hyperlipidaemia. Therefore, the granulomatous reaction observed could be associated with hyperlipidaemia...

journal_title：Clinical and experimental dermatology

authors： Lin WL,Kuo TT,Shih PY,Lin WC,Wong WR,Hong HS

更新日期：2007-09-01 00:00:00

abstract：:Naturally acquired anthrax infection remains an important public-health problem in developing countries. Turkey is one of the countries in which the zoonotic form of anthrax may still be encountered. The most frequent portal of entry for anthrax spores is the skin. Although cutaneous anthrax is usually self-limiting, ...

journal_title：Clinical and experimental dermatology

authors： Erkek E,Ayaslioglu E,Beygo B,Ozluk U

更新日期：2005-11-01 00:00:00

abstract：:Three children (two boys and one girl) from the same family presented with photosensitivity, hyperpigmentation, hypertrichosis, mild skin fragility, blistering and scarring in childhood. On examination, the cutaneous lesions were found to have improved since their previous examinations. Laboratory tests showed raised ...

journal_title：Clinical and experimental dermatology

authors： Remenyik E,Lecha M,Badenas C,Kószó F,Vass V,Herrero C,Varga V,Emri G,Balogh A,Horkay I

更新日期：2008-08-01 00:00:00

abstract：:This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

journal_title：Clinical and experimental dermatology

authors： Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

更新日期：1996-01-01 00:00:00

abstract：:Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficienc...

journal_title：Clinical and experimental dermatology

authors： Toms-Whittle LM,John LH,Buckley DA

更新日期：2011-04-01 00:00:00

abstract：:Postinflammatory hypopigmentation is a common cause of acquired hypopigmentary disorders. It can be a result of cutaneous inflammation, injury or dermatological treatment. There are also many specific conditions that present with hypopigmentation other than postinflammatory hypopigmentation. Most cases of postinflamma...

journal_title：Clinical and experimental dermatology

authors： Vachiramon V,Thadanipon K

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Epidermal replacement is an important step in the management of patients with post-traumatic and iatrogenic scars. Skin-colour variation from disease or trauma causes significant changes in self-image and appearance. AIM:The aim of our study was to analyse the results obtained with a novel autologous cell-h...

journal_title：Clinical and experimental dermatology

authors： Cervelli V,De Angelis B,Spallone D,Lucarini L,Arpino A,Balzani A

更新日期：2010-10-01 00:00:00

abstract：:The Buschke-Loewenstein tumour is regarded as a type of verrucous carcinoma occurring on anogenital mucosal surfaces. The tumour is locally invasive but displays a benign cytology and rarely metastasizes. It is associated with human papillomavirus types 6 and 11. We describe a case of Buschke-Loewenstein tumour occurr...

journal_title：Clinical and experimental dermatology

authors： Antony FC,Ardern-Jones M,Evans AV,Rosenbaum T,Russell-Jones R

更新日期：2003-01-01 00:00:00

abstract：:A case of anti-Ro (SS-A) antibody-positive subacute cutaneous lupus erythematosus (LE) occurring in a 47-year-old male with Crohn's disease is described. This is a previously undescribed association. ...

journal_title：Clinical and experimental dermatology

authors： Ashworth J

更新日期：1992-03-01 00:00:00

abstract：:Genetic factors predisposing individuals to Behçet's disease (BD) are considered to play important roles in the development of the disease. Patients with BD exhibit elevated levels of pro-inflammatory cytokines, and affected organs show a significant neutrophil and lymphocyte infiltration. Current evidence suggests th...

journal_title：Clinical and experimental dermatology

authors： Sallakci N,Bacanli A,Coskun M,Yavuzer U,Alpsoy E,Yegin O

更新日期：2005-09-01 00:00:00

abstract：:Malignant eccrine spiradenoma (MES) is an extremely rare cutaneous malignant tumour. An 86-year-old man presented at our hospital with an enlarging tumour on the dorsum of the left hand. An excisional biopsy was taken and histological examination showed a solid island of cells of two distinct types: cells with abundan...

journal_title：Clinical and experimental dermatology

authors： Tanese K,Sato T,Ishiko A

更新日期：2010-01-01 00:00:00

abstract：:We report a case of the rare porokeratosis variant porokeratosis ptychotropica (PP). A circumferential perianal plaque and the characteristic histology of multiple cornoid lamellae with underlying dermal amyloid deposition were seen. Amyloid deposition was seen in the biopsied intertriginous area of the plaque only, w...

journal_title：Clinical and experimental dermatology

authors： Tallon B,Blumental G,Bhawan J

更新日期：2009-12-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomas is an autosomal dominant condition that results in benign smooth muscle tumours of the skin and, in females, uterine fibroids. This syndrome overlaps with hereditary leiomyomatosis and renal cell cancer syndrome in which affected individuals may develop the rare type II papill...

journal_title：Clinical and experimental dermatology

authors： Chan I,Wong T,Martinez-Mir A,Christiano AM,McGrath JA

更新日期：2005-01-01 00:00:00

abstract：:We describe a case of a 67-year-old woman with a 1-year history of nail thickening and a non-itchy erythematous scaly eruption on the fingertips. She was diagnosed with psoriasis and started on methotrexate after having had no response to topical calcipotriol. The diagnosis was reviewed after it was revealed by anothe...

journal_title：Clinical and experimental dermatology

authors： Goyal NN,Wong GA

更新日期：2008-03-01 00:00:00

abstract：:Palmoplantar punctate keratoses may be the main cutaneous sign of various diseases (porokeratosis punctata palmaris et plantaris, keratosis punctata of the palmar creases, familial punctate palmoplantar keratoderma) or represent a secondary feature [Cowden's syndrome (CS) and Darier's disease]. In CS, such keratoses u...

journal_title：Clinical and experimental dermatology

authors： Ferran M,Bussaglia E,Matias-Guiu X,Pujol RM

更新日期：2009-07-01 00:00:00

abstract：:Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction, which is mostly due to drugs, but which has also been described as occurring after infections. We report a case of severe AGEP with extensive blistering mimicking toxic epidermal necrolysis (TEN) in a 47-year-old woman. This was ...

journal_title：Clinical and experimental dermatology

authors： Azib S,Florin V,Fourrier F,Delaporte E,Staumont-Sallé D

更新日期：2014-08-01 00:00:00

abstract：:A family with pachyonychia congenita in which affected individuals showed nail involvement only is described. Pachyonychia congenita is a rare hereditary disorder inherited in an autosomal dominant manner. Various classifications of pachyonychia congenita have been suggested but none indicates nail involvement as a so...

journal_title：Clinical and experimental dermatology

authors： Pryce DW,Verbov JL

更新日期：1994-11-01 00:00:00

abstract：:Systemic sclerosis (SSc) is often complicated by severe skin ulcers that are unresponsive to traditional treatments. Vascular alterations are responsible for the ischaemic features of the disease in both the skin and visceral organs. Defective neoangiogenesis correlates with an abnormally reduced quantity of circulati...

journal_title：Clinical and experimental dermatology

authors： Ferri C,Giuggioli D,Manfredi A,Quirici N,Scavullo C,Colaci M,Gianelli U,Deliliers GL,Del Papa N

更新日期：2010-12-01 00:00:00

abstract：:Stewart-Bluefarb syndrome (SBS) is a subtype of pseudo-Kaposi sarcoma (PKS), which is associated with congenital arteriovenous malformation. It is a rare syndrome, characterized by cutaneous lesions with onset in the second decade of life. We report a case of SBS in a 33-year-old man presenting with a 15-year history ...

journal_title：Clinical and experimental dermatology

authors： Verma SB,Vasani R

更新日期：2016-07-01 00:00:00

abstract：:Postgraduate higher specialist training of dermatology in the UK has become more structured over the past 8 years. Increased awareness of the need to police our profession has impelled the introduction of objective competency based assessment. Competency assessment will take three forms: mini clinical evaluation exerc...

journal_title：Clinical and experimental dermatology

authors： Griffiths CE

更新日期：2004-09-01 00:00:00

abstract：:Ras-associated autoimmune leucoproliferative disorder (RALD) is a nonmalignant syndrome associated with somatic KRAS mutations. We report a patient with RALD and cutaneous lesions, the first such case reported, to our knowledge. An 8-year-old boy presented with erythematous plaques on his face and body, along with lym...

journal_title：Clinical and experimental dermatology

authors： Giacaman A,Bauzá Alonso A,Salinas Sanz JA,Dapena Díaz JL,Ramos Asensio R,Ferrés Ramis L,Durán Pastor MA,Martín-Santiago A

更新日期：2018-12-01 00:00:00

abstract：:A 72-year-old woman with chronic renal failure requiring haemodialysis developed acute iododerma twice, after receiving iodide contrast dye for radiological procedures. Iododerma was localized to the face, scalp and elbows and was associated with papular purpura of the legs. Histopathology of the skin lesions showed a...

journal_title：Clinical and experimental dermatology

authors： Vaillant L,Pengloan J,Blanchier D,De Muret A,Lorette G

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Identification of onychomycosis is mainly based on clinical diagnosis with auxiliary diagnostic methods such as potassium hydroxide (KOH) microscopy, periodic acid-Schiff staining or fungal culture. However, each method is limited by its sensitivity and specificity. AIM:To develop a new test method using th...

journal_title：Clinical and experimental dermatology

authors： Ho WT,Li Y,Yang S

更新日期：2019-06-01 00:00:00