Quality of life, emotion dysregulation, attention deficit and psychiatric comorbidity in children and adolescents with vitiligo.


BACKGROUND:Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). AIM:To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. METHODS:In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched healthy controls (HCs) were included in the study. The Children's Depression Inventory, Screen for Child Anxiety Related Disorders, State-Trait Anxiety Inventory for Children and Child Somatization Inventory were completed for both patients and controls. The Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL) was administered to all patients by a child psychiatrist. Families were also asked to complete the Pediatric Quality of Life Inventory and Emotion Regulation Checklist for children. RESULTS:The K-SADS-PL evaluation showed that 90% of the patients in the vitiligo group had at least one psychiatric diagnosis, whereas this rate was 20% in the HCs (P < 0.001). There were statistically significant differences between vitiligo and HCs in terms of anxiety, state and trait anxiety scores (P < 0.05). Attention deficit and hyperactivity disorder (ADHD) was detected in 36.6% of the patients. CONCLUSION:The most important finding of this study is that anxiety disorders are more prominent than depression in childhood vitiligo. Another important finding of this study is that the prevalence of ADHD is significantly higher than the normal population.


Clin Exp Dermatol


Ucuz I,Altunisik N,Sener S,Turkmen D,Kavuran NA,Marsak M,Colak C




Has Abstract


2020-02-16 00:00:00






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    abstract::Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease originating from the pilosebaceous unit, in which patients develop painful abscesses, sinus tracts, nodules and scarring, typically in intertriginous areas. Major gaps in our understanding of HS exist, and these may be partially due to the lack of an...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Quartey QQ,Miller RJ,Pinsker BL,Okoh UJ,Shipman WD,George BA,Nwizu CC,Barnes LA,Kerns ML,Caffrey JA,Aliu O,Brown ID,Succaria F,Maynard JP,Herbert AS,Kang S,Miller LS,Okoye GA,Byrd AS

    更新日期:2020-03-01 00:00:00

  • Atypical Spitz tumour: a 'chameleon' lesion.

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: de Giorgi V,Sestini S,Massi D,Papi F,Lotti T

    更新日期:2008-05-01 00:00:00

  • Pityriasis rotunda as an incidental paraneoplastic finding in two patients with multiple myeloma.

    abstract::Pityriasis rotunda (PR) is an uncommon chronic dermatosis, which may be idiopathic or may be associated with infections or malignancy. We describe the clinical and biochemical findings of two patients with multiple myeloma, who were incidentally diagnosed with PR, and detail the clinical conditions with which this rar...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: van Heerden T,Webb MJ,Barrett CL

    更新日期:2014-08-01 00:00:00

  • Divided naevus of the penis: two paediatric cases with dermoscopic findings.

    abstract::Divided or kissing naevi are located on adjacent parts of the body that are separated during embryogenesis. Divided naevus of the penis (DNP) is exceedingly rare, with < 15 cases reported in the English language literature. Divided penile naevi affect the glans penis and inner foreskin, which are anatomical structures...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Mendes CP,Samorano LP,Alessi SS,Nico MM

    更新日期:2014-08-01 00:00:00

  • Association between long-term acitretin therapy and osteoporosis: no evidence of increased risk.

    abstract::Osteoporosis has been observed with chronic hypervitaminosis A, leading some authors to hypothesize that systemic retinoids may have an effect on bone mineral density. Two previous small studies identified osteoporosis in patients who received long-term therapy with etretinate. Etretinate has now been superceeded by a...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: McMullen EA,McCarron P,Irvine AD,Dolan OM,Allen GE

    更新日期:2003-05-01 00:00:00

  • Surgical plume in dermatology: an insidious and often overlooked hazard.

    abstract::Dermatologists performing surgical procedures face occupational and health hazards when exposed to surgical plume released during electrosurgical and ablative laser procedures. These hazardous fumes have toxic, infectious and carcinogenic effects. Understanding this risk is of particular importance during the COVID-19...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


    authors: Searle T,Ali FR,Al-Niaimi F

    更新日期:2020-10-01 00:00:00

  • Severe acute generalized exanthematous pustulosis with blistering mimicking toxic epidermal necrolysis, associated with a primary mumps infection.

    abstract::Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction, which is mostly due to drugs, but which has also been described as occurring after infections. We report a case of severe AGEP with extensive blistering mimicking toxic epidermal necrolysis (TEN) in a 47-year-old woman. This was ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Azib S,Florin V,Fourrier F,Delaporte E,Staumont-Sallé D

    更新日期:2014-08-01 00:00:00

  • Monoallelic expression on autosomes may explain an unusual heritable form of pigmentary mosaicism: a historical case revisited.

    abstract::A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...

    journal_title:Clinical and experimental dermatology

    pub_type: 信件


    authors: Happle R

    更新日期:2009-10-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Kumar B,Saraswat A,Kaur I

    更新日期:2002-01-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Mayer RD,Smith NP

    更新日期:1993-03-01 00:00:00

  • Multiple warty dyskeratomas of the scalp.

    abstract::Two patients presented with the unusual condition of multiple warty dyskeratomas on the scalp. Biopsies of affected skin stained positive with human keratin monoclonal antibodies HKN-6 and -7, specific for cortex and inner root sheath of normal human hair, respectively. Multiple warty dyskeratomas are a rare occurrenc...

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    pub_type: 杂志文章


    authors: Griffiths TW,Hashimoto K,Sharata HH,Ellis CN

    更新日期:1997-07-01 00:00:00

  • Cutis marmorata telangiectatica congenita: a prospective study of 27 cases and review of the literature with proposal of diagnostic criteria.

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


    authors: Kienast AK,Hoeger PH

    更新日期:2009-04-01 00:00:00

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    abstract:INTRODUCTION:Studies have found that the interleukin-23/T helper 17 (IL-23/Th17) pathway plays an important role in the pathogenesis of atopic dermatitis (AD). Inhibition of the IL-23/Th17 pathway with monoclonal antibodies reduces skin inflammation in animal models. AIM:To investigate the association between IL-17A a...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Narbutt J,Wojtczak M,Zalińska A,Salinski A,Przybylowska-Sygut K,Kuna P,Majak P,Sysa-Jedrzejowska A,Lesiak A

    更新日期:2015-01-01 00:00:00

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    abstract::Human papilloma virus is a common and often distressing cutaneous disease. It can be therapeutically challenging, especially in immunocompromised patients. We report a case of recalcitrant cutaneous warts that resolved with intravenous cidofovir treatment. The patient was immunocompromised secondary to monoclonal anti...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: McAleer MA,Bourke J

    更新日期:2011-08-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Takahashi H,Ishida-Yamamoto A,Iizuka H

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Toonstra I,van der Putte SC,de la Faille HB,van Vloten WA

    更新日期:1993-03-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Beattie PE,Dawe RS,Ibbotson SH,Ferguson J

    更新日期:2006-03-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


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    更新日期:2014-04-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Ryu KJ,Yoou MS,Seo Y,Yoon KW,Kim HM,Jeong HJ

    更新日期:2018-10-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: He L,Dang L,Zhou J,Bai J,Li YZ

    更新日期:2015-07-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Xue S,Li L

    更新日期:2011-10-01 00:00:00

  • The association of hepatitis C viral infection with porphyria cutanea tarda in the Lothian region of Scotland.

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Hussain I,Hepburn NC,Jones A,O'Rourke K,Hayes PC

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Janmohamed SR,de Waard-van der Spek FB,Madern GC,de Laat PC,Hop WC,Oranje AP

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Payne CM,Doe PT

    更新日期:1998-01-01 00:00:00

  • Ultraviolet A1 phototherapy: a British Photodermatology Group workshop report.

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    pub_type: 杂志文章,评审


    authors: Kerr AC,Ferguson J,Attili SK,Beattie PE,Coleman AJ,Dawe RS,Eberlein B,Goulden V,Ibbotson SH,Menage Hdu P,Moseley H,Novakovic L,Walker SL,Woods JA,Young AR,Sarkany RP

    更新日期:2012-04-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Mi X,Lai K,Yan L,Xie S,Qiu X,Xiao S,Wei S

    更新日期:2020-12-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


    authors: Innocenzi D,Barduagni F,Cerio R,Wolter M

    更新日期:1994-05-01 00:00:00

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    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: de Jong EM,van Erp PE,van Vlijmen IM,van de Kerkhof PC

    更新日期:1992-11-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2018-07-01 00:00:00