Abstract:
:The Buschke-Loewenstein tumour is regarded as a type of verrucous carcinoma occurring on anogenital mucosal surfaces. The tumour is locally invasive but displays a benign cytology and rarely metastasizes. It is associated with human papillomavirus types 6 and 11. We describe a case of Buschke-Loewenstein tumour occurring in a 61-year-old man which behaved in a locally aggressive manner and was associated with human papillomavirus type 16 and erythroderma which proved resistant to treatment. The patient refused surgery and therapy with interferon alpha was ineffective. Chemotherapy with systemic cisplatin and 5-fluorouracil produced a partial response before the patient succumbed from gram-negative septicaemia.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Antony FC,Ardern-Jones M,Evans AV,Rosenbaum T,Russell-Jones Rdoi
10.1046/j.1365-2230.2003.01167.xkeywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
46-9issue
1eissn
0307-6938issn
1365-2230pii
1167journal_volume
28pub_type
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