Disseminated superficial porokeratosis: what is the association with ultraviolet radiation?

abstract：:We describe an 18-year-old girl with systemic lupus erythematosus (SLE) who had cutaneous papulonodular mucinosis (PNM) as the first sign of SLE. She presented with multiple flesh-coloured papules on the face, abdomen and limbs. Histological examination of a biopsy taken from a papule showed diffuse deposition of muci...

journal_title：Clinical and experimental dermatology

authors： Shekari AM,Ghiasi M,Ghasemi E,Kani ZA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Hypohidrotic ectodermal dysplasia (HED) is a rare genetic disease. The clinical presentation includes lack of sweating ability, and an often widely spread dermatitis resembling atopic dermatitis (AD). In AD, the skin-barrier defect is partly ascribed to the altered lipid profile in the stratum corneum and pa...

journal_title：Clinical and experimental dermatology

authors： Jungersted JM,Høgh JK,Hellgren LI,Agner T,Jemec GB

更新日期：2012-03-01 00:00:00

abstract：:Blistering distal dactylitis (BDD) manifests as acral oval bullae 10-30 mm in diameter, and is caused by infection with Gram-positive bacteria. BDD was first linked to infection with group A beta-haemolytic streptococcus in children, but has more recently linked to Staphylococcus aureus and noted in adults. BDD most c...

journal_title：Clinical and experimental dermatology

authors： Scheinfeld NS

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (HHV) reactivation. The diagnosis of DIHS is ba...

journal_title：Clinical and experimental dermatology

authors： Teraki Y,Shibuya M,Izaki S

更新日期：2010-10-01 00:00:00

abstract：:Klippel-Trenaunay (KT) syndrome is a vascular malformation characterized by a port-wine stain, varicose veins and hypertrophy of the affected limb. Ulceration is considered an uncommon complication of KT syndrome and occurrence of skin cancer has been previously reported only in one case. We observed a case of KT synd...

journal_title：Clinical and experimental dermatology

authors： De Simone C,Giampetruzzi AR,Guerriero C,De Masi M,Amerio P,Cina G

更新日期：2002-05-01 00:00:00

abstract：:We present two patients who developed pseudoporphyria whilst taking isotretinoin (Roaccutane). At that time, both patients were receiving other agents which could be incriminated as causing their pseudoporphyria. However, it is significant that these other agents had been longstanding and that the porphyria-like cutan...

journal_title：Clinical and experimental dermatology

authors： Riordan CA,Anstey A,Wojnarowska F

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Port-wine stains (PWS) are congenital capillary malformations that persist throughout life. Laser therapy is a common treatment for PWS, and pulsed-dye laser is the current treatment of choice. AIM:To compare the clinical results on untreated PWS of two dye lasers with different wavelengths and pulse durati...

journal_title：Clinical and experimental dermatology

authors： Frohm Nilsson M,Passian S,Wiegleb Edstrom D

更新日期：2010-03-01 00:00:00

abstract：:Eleven cases of cutaneous B-cell lymphoma (CBCL) were studied. The ages at presentation ranged from 34 to 79 years (mean = 59.9 years). Six patients were female and five male. Five of the 11 patients had a solitary tumour and the other six had multiple tumours at initial presentation. According to Burg's classificatio...

journal_title：Clinical and experimental dermatology

authors： Nagatani T,Miyazawa M,Matsuzaki T,Hayakawa H,Iemoto G,Kim ST,Baba N,Aihara M,Miyamoto H,Nakajima H

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM:To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS:The medical records of all the patients with p...

journal_title：Clinical and experimental dermatology

authors： Qiu Y,Ma G,Yang J,Hu X,Chen H,Jin Y,Lin X

更新日期：2013-12-01 00:00:00

abstract：:Summary Mid-dermal elastolysis is an unusual process characterized by the absence of the elastic fibres within the mid-dermis. The disappearance of these fibres causes fine wrinkles (type 1) or perifollicular protrusions (type 2) affecting the trunk, neck and arms. There is a female predilection, and most patients hav...

journal_title：Clinical and experimental dermatology

authors： Cutillas E,Ferrando FJ,Martí ME,Mateu A,Rausell N

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Multipotent cells can be isolated from dermis, and have wound-healing and antioxidant effects on human and murine skin. AIM:To investigate the changes in aged dermis after injection of dermal multipotent cells and adult fibroblasts. METHODS:Dermal multipotent cells were isolated and cultured from 3-day-old...

journal_title：Clinical and experimental dermatology

authors： Xue S,Li L

更新日期：2011-10-01 00:00:00

abstract：:Tetracyclines, including doxycycline, are widely used drugs that form an integral part of daily prescribing, and serious adverse reactions (SARs) are rarely reported. The frequency of hypoglycaemia complicating tetracycline treatment remains unknown, and is not a recognized complication. We describe an 80-year-old man...

journal_title：Clinical and experimental dermatology

authors： Tan CH,Shelley C,Harman KE

更新日期：2016-01-01 00:00:00

abstract：:Langerhans cells at the site of patch tests to inhaled allergens in patients with atopic dermatitis were investigated. Within 24 h the Langerhans cells showed increased cellular activity and became apposed to mononuclear cells. This supports the view that Langerhans cells are involved in antigen presentation in atopic...

journal_title：Clinical and experimental dermatology

authors： Najem N,Hull D

更新日期：1989-05-01 00:00:00

abstract：:Urticarial vasculitis (UV) is a mainly leucocytoclastic vasculitis with urticarial plaques. Treating these patients is challenging as the available treatments have poor efficacy. Oral corticosteroids are considered the first-line treatment, but H1 antihistamines, dapsone, colchicine, antimalarials, ciclosporin and ant...

journal_title：Clinical and experimental dermatology

authors： Fueyo-Casado A,Campos-Muñoz L,González-Guerra E,Pedraz-Muñoz J,Cortés-Toro JA,López-Bran E

更新日期：2017-06-01 00:00:00

abstract：:Severe cases of psoriasis and psoriasis arthritis require systemic treatment. Although a number of established drugs are in clinical use, there is a need for new compounds with an improved risk-benefit ratio with a major emphasis on long-term safety. Furthermore, patients with moderate psoriasis ask for systemic drugs...

journal_title：Clinical and experimental dermatology

authors： Mrowietz U

更新日期：2001-06-01 00:00:00

abstract：:Endemic pemphigus foliaceus (EPF) is an autoimmune disease, which occurs in Brazil and other regions of South America. Mannose-binding lectin (MBL) and MBL-associated serine protease (MASP-2) play a key role in innate immunity, and its deficiency has been related to increased susceptibility to infection and autoimmune...

journal_title：Clinical and experimental dermatology

authors： Messias-Reason I,Bosco DG,Nisihara RM,Jakobsen LH,Petzl-Erler ML,Jensenius JC

更新日期：2008-07-01 00:00:00

abstract：:We report a case of white fibrous papulosis of the neck in a 70-year-old Iranian woman. To date this recently reported entity has only been described in Japanese patients. This asymptomatic eruption characteristically affects the posterior neck. The pale papules are round to oval 2-3 mm in diameter, and not follicular...

journal_title：Clinical and experimental dermatology

authors： Cerio R,Gold S,Jones EW

更新日期：1991-05-01 00:00:00

abstract：:Previous studies on the association of smoking with acne vulgaris have reported conflicting results. The objective of this study was to investigate such an association. Our setting was three primary care practices in Hong Kong and one primary care practice in India. Patient characteristics in all four practices are si...

journal_title：Clinical and experimental dermatology

authors： Chuh AA,Zawar V,Wong WC,Lee A

更新日期：2004-11-01 00:00:00

abstract：:Rapp-Hodgkin syndrome (RHS) is an autosomal dominant disorder characterized by ectodermal dysplasia and cleft lip/cleft palate. Very recently, mutations in p63 have been identified as a cause of RHS; to date five such mutations have been identified. We describe a Thai girl with RHS. She had short stature, ectodermal d...

journal_title：Clinical and experimental dermatology

authors： Shotelersuk V,Janklat S,Siriwan P,Tongkobpetch S

更新日期：2005-05-01 00:00:00

abstract：:Determining the risk of progression to systemic lupus erythematosus (SLE) among patients diagnosed with discoid lupus erythematosus (DLE), and the time frame of this risk, are important clinical questions. Past reports have demonstrated a wide time frame of progression from DLE to SLE, with mean time to progression of...

journal_title：Clinical and experimental dermatology

authors： Elman SA,Joyce C,Costenbader KH,Merola JF

更新日期：2020-01-01 00:00:00

abstract：:Secukinumab is an interleukin (IL)-17 monoclonal antibody inhibiting T-helper (Th)1-mediated immune response. It has proven high efficacy for moderate to severe psoriasis but data on its long-term toxicities are limited. We describe two patients who received secukinumab for clinically presumed psoriasis, but were subs...

journal_title：Clinical and experimental dermatology

authors： Yoo J,Shah F,Velangi S,Stewart G,Scarisbrick JS

更新日期：2019-06-01 00:00:00

abstract：:A patient with primary malignant melanoma localized to the right gluteal region is described. Four years later and after intercurrent influenza, disseminated metastases of malignant melanoma to the skin occurred. After a further 6 months melanodermia developed and lasted until the death of the patient (6 months later)...

journal_title：Clinical and experimental dermatology

authors： Péc J,Plank L,Mináriková E,Palencárová E,Rollová Y,Lazárová Z,Auxtová S,Lauko L

更新日期：1993-09-01 00:00:00

abstract：:We report a case of a 56-year-old woman who presented with a severe exacerbation of psoriasis with concurrent hypoglycaemic episodes. Methotrexate 17.5 mg weekly was required to control her psoriasis. Investigation of her hypoglycaemia showed raised levels of insulin, C-peptide and proinsulin. Radiological investigati...

journal_title：Clinical and experimental dermatology

authors： Field S,Kelly G,Tobin AM,Barragry JM,Conlon KC,Kirby B

更新日期：2008-03-01 00:00:00

abstract：:Graham Little-Piccardi-Lassueur syndrome (GLPLS) is a rare lichenoid dermatosis defined by scarring alopecia, loss of pubic and axillary hairs and progressive development of horny follicular papules variously located. Topical or systemic corticosteroids, retinoids or PUVA therapy are the treatments usually proposed an...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Paro Vidolin A,Piemonte P,Carboni I,Chimenti S

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Vitiligo is a pigmentation disorder of autoimmune aetiology. Polymorphisms in beta-defensin genes have been linked to a predisposition to some autoimmune disorders. AIM:To evaluate the role of polymorphisms in DEFB1, the gene encoding for human beta-defensin (HBD)-1 and its 5' untranslated region in nonsegm...

journal_title：Clinical and experimental dermatology

authors： Ochoa-Ramírez LA,Becerra-Loaiza DS,Díaz-Camacho SP,Muñoz-Estrada VF,Ríos-Burgueño ER,Prado-Montes de Oca E,Rangel-Villalobos H,Velarde-Félix JS

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:We conducted a re-audit of the surgical practice of UK dermatologists for the treatment of nonmelanoma skin cancer and examined changes with reference to our previous audit in 2014. The audit was supplemented by a detailed assessment of completeness of the histopathology reports for each tumour. METHODS:UK ...

journal_title：Clinical and experimental dermatology

authors： Keith DJ,Bray AP,Brain A,Mohd Mustapa MF,Barrett HE,Lane S,Emmerich M,Jakes A,Barrett PD,de Berker DAR

更新日期：2020-01-01 00:00:00

abstract：:This randomized double-blind controlled study examined whether sulphydryl-containing agents influence the healing of venous ulceration occurring for the first time on the medial side of the leg. Graduated compression bandaging, which exerted a mean ankle pressure of 40.6 +/- 0.4 mmHg, and a mean below-knee pressure of...

journal_title：Clinical and experimental dermatology

authors： Salim AS

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Chronic cutaneous lesions affect 15% of human patients with diabetes, and the associated risk of limb amputations is 15-46 times greater than that of people with normal glycaemia. It is estimated that half of these limb amputations could be avoided by opportune treatment with somatic stem cells or platelet-r...

journal_title：Clinical and experimental dermatology

authors： Argôlo Neto NM,Del Carlo RJ,Monteiro BS,Nardi NB,Chagastelles PC,de Brito AF,Reis AM

更新日期：2012-07-01 00:00:00

abstract：:Refractory leg ulcers in two patients healed following splenectomy. Neither patient had the ethnic background or family history of haematological abnormalities to suggest a haemoglobinopathy. ...

journal_title：Clinical and experimental dermatology

authors： Lawrence P,Aronson I,Saxe N,Jacobs P

更新日期：1991-01-01 00:00:00

abstract：:We report the case of a 43-year-old woman, a longstanding heavy cigarette smoker, who developed Bürger's disease, leading to mid-thigh amputation of her left leg. After she gave up smoking her disease was arrested but Raynaud's phenomenon continues to affect her hands and right foot. In reviewing the literature, we fo...

journal_title：Clinical and experimental dermatology

authors： Abdullah AN,Keczkes K

更新日期：1990-01-01 00:00:00