Ceramide profile in hypohidrotic ectodermal dysplasia.

abstract：BACKGROUND:Data on the dermoscopic features of fungal melanonychia are limited. AIM:To identify the dermoscopic features of fungal melanonychia. METHODS:We reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past y...

journal_title：Clinical and experimental dermatology

authors： Kilinc Karaarslan I,Acar A,Aytimur D,Akalin T,Ozdemir F

更新日期：2015-04-01 00:00:00

abstract：:Severe cases of psoriasis and psoriasis arthritis require systemic treatment. Although a number of established drugs are in clinical use, there is a need for new compounds with an improved risk-benefit ratio with a major emphasis on long-term safety. Furthermore, patients with moderate psoriasis ask for systemic drugs...

journal_title：Clinical and experimental dermatology

authors： Mrowietz U

更新日期：2001-06-01 00:00:00

abstract：:We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one pat...

journal_title：Clinical and experimental dermatology

authors： Jacyk K,Smith A

更新日期：1990-09-01 00:00:00

abstract：:Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficienc...

journal_title：Clinical and experimental dermatology

authors： Toms-Whittle LM,John LH,Buckley DA

更新日期：2011-04-01 00:00:00

abstract：:This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

journal_title：Clinical and experimental dermatology

authors： Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is characterized by lymphocytic infiltrate, fibrosis and potential destruction of the hair follicle. Demographic and clinical studies in LPP are limited, and racial differences have not been thoroughly investigated. AIM:To analyse epidemiological data and clinical profiles of Chile...

journal_title：Clinical and experimental dermatology

authors： Mardones F,Shapiro J

更新日期：2017-10-01 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：:Palmoplantar punctate keratoses may be the main cutaneous sign of various diseases (porokeratosis punctata palmaris et plantaris, keratosis punctata of the palmar creases, familial punctate palmoplantar keratoderma) or represent a secondary feature [Cowden's syndrome (CS) and Darier's disease]. In CS, such keratoses u...

journal_title：Clinical and experimental dermatology

authors： Ferran M,Bussaglia E,Matias-Guiu X,Pujol RM

更新日期：2009-07-01 00:00:00

abstract：:The linear pattern of lichen planus (LP) is extremely rare. In six publications 1256 patients with LP have been reviewed and only three cases of linear LP (LLP) are reported. The differential diagnosis of LLP includes a number of linear dermatoses in particular lichen striatus (LS) and the extent of overlap between th...

journal_title：Clinical and experimental dermatology

authors： Herd RM,McLaren KM,Aldridge RD

更新日期：1993-07-01 00:00:00

abstract：:There is variation in the treatment of lower limb cellulitis (LLC) with no agreement on the most effective antibiotic regimen. Many patients with cellulitis fail to respond to first-line antibiotics. This can negatively affect patient care and result in unnecessary hospital admissions. The aim of this systematic revie...

journal_title：Clinical and experimental dermatology

authors： Mistry K,Sharma S,Patel M,Grindlay D,Janjuha R,Smart P,Levell NJ

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin carcinoma. AIM:To investigate the function of key micro(mi)RNAs and to explore the potential molecular mechanisms involved in BCC. METHODS:The microarray dataset GSE34535, which comprises seven BCC samples and seven control samples, was downloaded ...

journal_title：Clinical and experimental dermatology

authors： Mi X,Lai K,Yan L,Xie S,Qiu X,Xiao S,Wei S

更新日期：2020-12-01 00:00:00

abstract：:Neurotrophic ulceration of the face is a rare but well recognized sequel to division of the trigeminal nerve. Trauma is an important contributory factor and thought to be due in part to paraesthesiae, which encourages picking and scratching, with resultant chronic and persistent ulceration. A case is described of an 8...

journal_title：Clinical and experimental dermatology

authors： Mayer RD,Smith NP

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Momordica charantia (MC; bitter gourd) is a traditional herb commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. It is also used for the rapid healing of wounds. AIM:To observe the topical effect of MC extract on the wound-healing process in rats with diabetes induce...

journal_title：Clinical and experimental dermatology

authors： Teoh SL,Latiff AA,Das S

更新日期：2009-10-01 00:00:00

abstract：:Chronic spontaneous urticaria (CSU) is a common and disabling skin disease which is often associated with psychiatric comorbidities such as anxiety and depression. These conditions are widely thought to cause, drive and/or maintain CSU, and have been reported as making an important contribution to the low quality of l...

journal_title：Clinical and experimental dermatology

authors： Weller K,Koti I,Makris M,Maurer M

更新日期：2013-12-01 00:00:00

abstract：:A 34-year-old woman presented with 2-year history of a dome-shaped papule on a well-circumscribed, thickened, port-wine stain on the left side of the chin. Squeezing on the port-wine-stain plaque revealed many comedos within dilated follicular orifices. The papule was excised and submitted for histological examination...

journal_title：Clinical and experimental dermatology

authors： Yang CH,Shen SC,Yeh JT,Tsai YL,Hong HS

更新日期：2005-09-01 00:00:00

abstract：:It is well known that systemic corticosteroids arrest the progress of vitiligo and lead to repigmentation, but they may produce unacceptable side-effects. The use of high-dose prednisolone therapy to minimize the side-effects of systemic steroids has been reported, but there have been no reports on the effectiveness o...

journal_title：Clinical and experimental dermatology

authors： Lee Y,Seo YJ,Lee JH,Park JK

更新日期：2007-09-01 00:00:00

abstract：:Rapp-Hodgkin syndrome (RHS) is an autosomal dominant disorder characterized by ectodermal dysplasia and cleft lip/cleft palate. Very recently, mutations in p63 have been identified as a cause of RHS; to date five such mutations have been identified. We describe a Thai girl with RHS. She had short stature, ectodermal d...

journal_title：Clinical and experimental dermatology

authors： Shotelersuk V,Janklat S,Siriwan P,Tongkobpetch S

更新日期：2005-05-01 00:00:00

abstract：:IgA pemphigus is rare but may be underdiagnosed. We describe two cases, a 50-year-old female with a pustular eruption resembling subcorneal pustular dermatosis and a 55-year-old male with a pruritic vesiculopustular eruption simulating dermatitis herpetiformis. They illustrate the clinical heterogeneity of IgA pemphig...

journal_title：Clinical and experimental dermatology

authors： Harman KE,Holmes G,Bhogal BS,McFadden J,Black MM

更新日期：1999-11-01 00:00:00

abstract：:A 78-year-old Caucasian woman developed Sweet's syndrome which progressed over 3 weeks to pyoderma gangrenosum and subcorneal pustule formation. In spite of treatment the patient died and post-mortem examination revealed cryptogenic cirrhosis which could have explained the spectrum of neutrophilic skin disease observe...

journal_title：Clinical and experimental dermatology

authors： Davies MG,Hastings A

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Recently, increased evidence has shown that serum micro (mi)RNA levels are a useful biomarker for the diagnosis, prognosis and therapeutic value of various diseases. However, serum miRNA has not been investigated in patients with systemic sclerosis (SSc), to our knowledge. AIM:To investigate the possibility...

journal_title：Clinical and experimental dermatology

authors： Makino K,Jinnin M,Kajihara I,Honda N,Sakai K,Masuguchi S,Fukushima S,Inoue Y,Ihn H

更新日期：2012-01-01 00:00:00

abstract：:Contact hypersensitivity from topical corticosteroids is becoming increasingly recognized; it is present in 2-5% of the patients attending contact dermatitis clinics. The use of a corticosteroid series containing tixocortal pivalate 1% (petrolatum), to detect hypersensitivity to hydrocortisone, and other steroids 1% (...

journal_title：Clinical and experimental dermatology

authors： Wilkinson SM

更新日期：1994-01-01 00:00:00

abstract：:A case of Bowen's disease is described in which striking quantities of amyloid were detected in the papillary dermis visualized easily by routine haematoxylin and eosin staining. The material showed positive labelling with an antikeratin monoclonal antibody consistent with the proposed origin of the amyloid as degener...

journal_title：Clinical and experimental dermatology

authors： Speight EL,Milne DS,Lawrence CM

更新日期：1993-05-01 00:00:00

abstract：:Despite the negative effects of androgenetic alopecia (AGA), no standardized health-related quality of life (HRQOL) questionnaire which is both specific to women and suitable for use in clinical trials currently exists. A questionnaire to assess HRQOL in women with AGA, the Women's Androgenetic Alopecia Quality of Lif...

journal_title：Clinical and experimental dermatology

authors： Dolte KS,Girman CJ,Hartmaier S,Roberts J,Bergfeld W,Waldstreicher J

更新日期：2000-11-01 00:00:00

abstract：:Cutaneous amyloidosis and multiple endocrine neoplasia 2A (MEN 2A) have been previously reported in several families. A genetic linkage of both disorders has recently been described. Notalgia paraesthetica has been suggested to be involved in the aetiology of amyloidosis in such patients. We report such an association...

journal_title：Clinical and experimental dermatology

authors： de Argila D,Ortiz-Romero PL,Ortiz-Frutos J,Rodriguez-Peralto JL,Iglesias L

更新日期：1996-07-01 00:00:00

abstract：:Human papillomavirus (HPV) is the most common sexually transmitted disorder in young, sexually active populations in the USA and Europe. Giant condyloma acuminatum (GCA) is a unique variant of condyloma acuminata, characterized by local aggressive behaviour despite benign histology. It carries a substantial risk of sq...

journal_title：Clinical and experimental dermatology

authors： Erkek E,Basar H,Bozdogan O,Emeksiz MC

更新日期：2009-04-01 00:00:00

abstract：:We report a 29-year-old white woman who presented with oral involvement and subsequently developed severe and extensive laryngeal involvement with mucous membrane pemphigoid. She could not tolerate systemic corticosteroids due to side-effects. Dapsone improved only the oral disease, but the laryngeal disease remained ...

journal_title：Clinical and experimental dermatology

authors： Gürcan HM,Ahmed AR

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (HHV) reactivation. The diagnosis of DIHS is ba...

journal_title：Clinical and experimental dermatology

authors： Teraki Y,Shibuya M,Izaki S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) and lentigo maligna melanoma (LMM) can be difficult to manage surgically. Predetermined margins can be inadequate because of subclinical spread, or can affect function when margins are adjacent to the eye or mouth. AIM:To describe our 5-year experience in Nottingham of using the staged ...

journal_title：Clinical and experimental dermatology

authors： Patel AN,Perkins W,Leach IH,Varma S

更新日期：2014-07-01 00:00:00

abstract：:Sensitive skin (SS) is a widespread condition, but still not completely understood. To identify risk factors that increase the likelihood of SS, 258 women aged between 20 and 65 years old and resident in the Netherlands were surveyed by questionnaire, which included questions on sociodemographic characteristics (age g...

journal_title：Clinical and experimental dermatology

authors： Falcone D,Richters RJH,Uzunbajakava NE,van Erp PEJ,van de Kerkhof PCM

更新日期：2017-08-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomata (MCL) is an autosomal dominant disorder characterized by the development of benign smooth muscle tumours (leiomyomas) in the skin and uterus of affected women, and in the skin of affected men. In rare cases, MCL has been associated with a predisposition to the rare type II pa...

journal_title：Clinical and experimental dermatology

authors： Chuang GS,Martinez-Mir A,Engler DE,Gmyrek RF,Zlotogorski A,Christiano AM

更新日期：2006-01-01 00:00:00