Association of human beta-defensin 1 gene polymorphisms with nonsegmental vitiligo.

abstract：:The incidence of nonmelanoma skin cancer is significantly increased in recipients of solid-organ transplants. Photodynamic therapy (PDT) is a well-documented treatment option for superficial and selected nodular basal cell carcinomas (BCCs) in immunocompetent patients, but there are few reports describing PDT of BCCs ...

journal_title：Clinical and experimental dermatology

authors： Guleng GE,Helsing P

更新日期：2012-06-01 00:00:00

abstract：:High-dose intravenous immunoglobulin (hdIVIg) is being used increasingly for dermatological indications. Its mode of action is via a number of proposed mechanisms and it is not associated with the many side-effects of steroids and other immunosuppressive agents. The evidence for using hdIVIg in the treatment of autoim...

journal_title：Clinical and experimental dermatology

authors： Jolles S

更新日期：2001-03-01 00:00:00

abstract：:We report the case of a 28-year-old homosexual man with advanced HIV disease (CDC classification group IV A) who developed erythrodermic psoriasis which responded to calcipotriol, a topical vitamin D analogue. We believe this to be the first reported case of HIV-related psoriasis responsive to this form of treatment. ...

journal_title：Clinical and experimental dermatology

authors： Gray JD,Bottomley W,Layton AM,Cotterill JA,Monteiro E

更新日期：1992-09-01 00:00:00

abstract：:Waldenström macroglobulinaemia (WM) is a chronic lymphoproliferative disorder characterized by the presence of a monoclonal IgM paraprotein. Specific cutaneous features of WM include neoplastic cell infiltrates, IgM storage papules and IgM bullous dermatosis. We report a patient with subepidermal bullous disease assoc...

journal_title：Clinical and experimental dermatology

authors： Chattopadhyay M,Rytina E,Dada M,Bhogal BS,Groves R,Handfield-Jones S

更新日期：2013-12-01 00:00:00

abstract：:Thalidomide has been used as an effective treatment for prurigo nodularis (PN) with a median dose of 200 mg, but the risk of peripheral neuropathy precludes long-term use. We analysed the efficacy of low-dose thalidomide (< 100 mg) in 17 patients with recalcitrant PN. Patients were initiated on thalidomide 50 mg on al...

journal_title：Clinical and experimental dermatology

authors： Sardana K,Gupta A,Sinha S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Metallothioneins (MTs) are a group of proteins widely distributed in tissues regulating metal metabolism, scavenging free radicals, and taking part in immunological reactions. Knockout mice for MT genes I and II (MT(-/-)) exhibit reduced tolerance to ultraviolet B injury in vivo. Upregulation of MT proteins ...

journal_title：Clinical and experimental dermatology

authors： Ma C,Li LF,Zhang BX

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease caused by genetic and epigenetic factors. There are conflicting results in the literature about the association between psoriasis and the methylenetetrahydrofolate reductase gene (MTHFR), ranging from strong linkage to no association. AIM:To investigat...

journal_title：Clinical and experimental dermatology

authors： Kilic S,Ozdemir O,Silan F,Isik S,Yildiz O,Karaagacli D,Silan C,Ogretmen Z

更新日期：2017-01-01 00:00:00

abstract：:A 15-year-old boy with Kaposi's varicelliform eruption complicating healing second degree burns is reported. Clinically, umbilicated vesicles and pustules evolving to extensive erosions appeared over previously burned areas, sparing normal skin. Rapid diagnosis was made on the basis of the presence of multinucleate gi...

journal_title：Clinical and experimental dermatology

authors： Bartralot R,García-Patos V,Rodríguez-Cano L,Castells A

更新日期：1996-03-01 00:00:00

abstract：:The use of cyclosporin A (CSA) for the treatment of severe psoriasis is well established. However its use is limited by its adverse effects, especially nephrotoxicity. We reviewed 28 patients treated with CSA for severe psoriasis over an 11-year period. All patients were on long-term CSA treatment (median duration 55....

journal_title：Clinical and experimental dermatology

authors： Markham T,Watson A,Rogers S

更新日期：2002-03-01 00:00:00

abstract：:Majocchi's granuloma, also known as nodular granulomatous perifolliculitis, is an uncommon fungal infection of the skin and subcutaneous tissue. It can occur in healthy and immunocompromised patients. The most common cause of Majocchi's granuloma is Trichophyton rubrum. We report a case of a Majocchi's granuloma cause...

journal_title：Clinical and experimental dermatology

authors： Saadat P,Kappel S,Young S,Abrishami M,Vadmal MS

更新日期：2008-07-01 00:00:00

abstract：:Contact allergy to various essential oils used in aromatherapy was demonstrated on patch testing in a 53-year-old patient suffering from relapsing eczema resistant to therapy on various uncovered parts of the skin, in particular the scalp, neck and hands. Sensitization was due to previous exposure to lavender, jasmine...

journal_title：Clinical and experimental dermatology

authors： Schaller M,Korting HC

更新日期：1995-03-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease affecting the skin folds. Multiple therapeutic options have been proposed for severe cases, but persistent responses are rarely seen. Important complications of HS are uncommon, and usually seen only in severe and unresponsive disease. Amyloid ...

journal_title：Clinical and experimental dermatology

authors： Utrera-Busquets M,Romero-Maté A,Castaño Á,Alegre L,García-Donoso C,Borbujo J

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Psoriasis involves a multifaceted interplay of keratinocytes, blood vessels, immune system mediators and expressed genes. AIM:To determine whether genetic polymorphisms in the angiopoietin-1 (ANGPT1), angiopoietin-2 (ANGPT2) and caspase-5 (CASP5) genes are associated with an increased risk of developing pso...

journal_title：Clinical and experimental dermatology

authors： He L,Dang L,Zhou J,Bai J,Li YZ

更新日期：2015-07-01 00:00:00

abstract：:A 93-year-old woman with an 8-year history of episodes of fixed drug eruption due to paracetamol is described. The rash was characterized by bullae, crusted lesions, hyperpigmented and erythematous patches as well as lesions resembling toxic epidermal necrolysis. Direct immunofluorescence revealed deposition of IgG an...

journal_title：Clinical and experimental dermatology

authors： Duhra P,Porter DI

更新日期：1990-07-01 00:00:00

abstract：:Pyostomatitis vegetans is a rare oral disorder often associated with gastrointestinal and/or cutaneous diseases and sometimes with other disorders. The association of pyostomatitis vegetans with inflammatory bowel disease, particularly ulcerative colitis, is well known and in most cases bowel disease precedes the onse...

journal_title：Clinical and experimental dermatology

authors： Hegarty AM,Barrett AW,Scully C

更新日期：2004-01-01 00:00:00

abstract：:Although Q-switched (QS) lasers are the mainstay of modern tattoo removal, paradoxical darkening of tattoo ink may occur. This darkening of tattoo ink is dependent on laser wavelength, pulse duration and fluence, with high-energy, nanosecond-pulsed lasers more prone to induce tattoo-ink darkening. Laser toning, consis...

journal_title：Clinical and experimental dermatology

authors： Chung WK,Yang JH,Lee DW,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2009-12-01 00:00:00

abstract：:Secukinumab is an interleukin (IL)-17 monoclonal antibody inhibiting T-helper (Th)1-mediated immune response. It has proven high efficacy for moderate to severe psoriasis but data on its long-term toxicities are limited. We describe two patients who received secukinumab for clinically presumed psoriasis, but were subs...

journal_title：Clinical and experimental dermatology

authors： Yoo J,Shah F,Velangi S,Stewart G,Scarisbrick JS

更新日期：2019-06-01 00:00:00

abstract：:We report the occurrence of severe symptomatic bronchoconstriction in an atopic asthmatic subject following the application of coal tar bandages. Investigations showed that this was likely to have been caused by inhalation of coal tar vapour. We suggest that coal tar preparations should be used with caution in asthmat...

journal_title：Clinical and experimental dermatology

authors： Ibbotson SH,Stenton SC,Simpson NB

更新日期：1995-01-01 00:00:00

abstract：:We report the case of a 30-year-old patient who developed scombrotoxic fish poisoning after eating cooked fresh tuna. Symptoms included a bright red rash, tightness of the chest, palpitations, anxiety, mild headache and dizziness, all of which resolved spontaneously within 2-3 h. Such poisoning results from the consum...

journal_title：Clinical and experimental dermatology

authors： Sabroe RA,Kobza Black A

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:The protein kynureninase (KYNU) has recently been reported to participate in the pathological processes of various diseases. AIM:To explore the expression and the biological function of KYNU in cutaneous squamous cell carcinoma (cSCC). METHODS:Expression of KYNU in cSCC cell lines and tissues was firstly e...

journal_title：Clinical and experimental dermatology

authors： Ci C,Wu C,Lyu D,Chang X,He C,Liu W,Chen L,Ding W

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Haptoglobin (Hp) is one of the acute phase proteins, whose main function is to bind free haemoglobin (Hb) and transport it to the liver for degradation and iron recycling. In addition to its role as an Hb scavenger, Hp has been shown to behave as an anti-inflammatory, antioxidant and angiogenic factor. We pr...

journal_title：Clinical and experimental dermatology

authors： Maresca B,Lembo S,Ayala F,Balato N,Di Caprio R,Mattii M,Raimondo A,Schiattarella M,Abrescia P,Spagnuolo MS,Cigliano L,Balato A

更新日期：2016-01-01 00:00:00

abstract：:Chronic photodamage of the skin manifests itself as extrinsic skin ageing (photoageing) and photocarcinogenesis. DNA photodamage and UV-generated reactive oxygen species are the initial molecular events that lead to most of the typical histological and clinical manifestations of chronic photodamage of the skin. Knowle...

journal_title：Clinical and experimental dermatology

authors： Trautinger F

更新日期：2001-10-01 00:00:00

abstract：:We describe a 26-year-old Indian man who presented with chickenpox and subsequently developed pemphigus vulgaris 17 days after initial resolution of lesions. The mechanism of progression from one disease to the other is postulated to be that of epitope spreading or molecular mimicry. ...

journal_title：Clinical and experimental dermatology

authors： Goon AT,Tay YK,Tan SH

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Recently, increased evidence has shown that serum micro (mi)RNA levels are a useful biomarker for the diagnosis, prognosis and therapeutic value of various diseases. However, serum miRNA has not been investigated in patients with systemic sclerosis (SSc), to our knowledge. AIM:To investigate the possibility...

journal_title：Clinical and experimental dermatology

authors： Makino K,Jinnin M,Kajihara I,Honda N,Sakai K,Masuguchi S,Fukushima S,Inoue Y,Ihn H

更新日期：2012-01-01 00:00:00

abstract：:We report a 73-year-old man who developed repeated episodes of erythematous, bullous plaques beginning 3 months after discontinuation of combination treatment with pegylated interferon (IFN)-alpha-2b and ribavirin for hepatitis C virus infection. The first episode resolved within a week without treatment, but the lesi...

journal_title：Clinical and experimental dermatology

authors： Sato M,Sueki H,Iijima M

更新日期：2009-12-01 00:00:00

abstract：:Clear cell acanthoma (CCA) is a benign epidermal tumour with distinctive and uniform clinical and histological features. Although solitary lesions are the rule, some cases of multiple CCA, rarely with more than 10 lesions, have been previously reported. Only 22 cases of multiple CCA have been described in the English ...

journal_title：Clinical and experimental dermatology

authors： Innocenzi D,Barduagni F,Cerio R,Wolter M

更新日期：1994-05-01 00:00:00

abstract：:A case of disseminated Kaposi sarcoma in a 76-year-old woman treated with low-dose steroids for a seronegative polyarthritis is described. HIV serology was negative, whereas PCR for HHV-8 was positive. The patient presented with a profound reduction in the peripheral blood CD4+ cell count and a decrease in serum immun...

journal_title：Clinical and experimental dermatology

authors： Fierro MT,Savoia P,Quaglino P,Novero D,Bernengo MG

更新日期：2005-07-01 00:00:00

abstract：:Aicardi-Goutières syndrome type 6 (AGS6) and dyschromatosis symmetrica hereditaria (DSH) are allelic disorders caused respectively by biallelic and heterozygous pathogenic variants in ADAR1. We report three unrelated children presenting with features of both AGS6 and DSH, two of whom had compound heterozygous pathogen...

journal_title：Clinical and experimental dermatology

authors： Sathishkumar D,Muthusamy K,Gupta A,Malhotra M,Thomas M,Koshy B,Jasper A,Danda S,George R

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common skin problem that affects up to 90% of adolescents. Colonization of the duct with Propionibacterium species is one of the factors implicated in the development of acne. Owing to the increasing incidence of antibiotic resistance, there has been an greater interest in the development ...

journal_title：Clinical and experimental dermatology

authors： Yung A,Stables GI,Fernandez C,Williams J,Bojar RA,Goulden V

更新日期：2007-11-01 00:00:00

abstract：:An earlier standard syphilology textbook states that 'If vesicles are an essential part of an eruption in an adult, the lesions are not due to secondary syphilis'. However, vesicular and bullous eruptions do occur in congenital syphilis and rare reports of both vesicular and pustular eruptions in adults with secondary...

journal_title：Clinical and experimental dermatology

authors： Lawrence P,Saxe N

更新日期：1992-01-01 00:00:00