Abstract:
:We report a case of a 56-year-old woman who presented with a severe exacerbation of psoriasis with concurrent hypoglycaemic episodes. Methotrexate 17.5 mg weekly was required to control her psoriasis. Investigation of her hypoglycaemia showed raised levels of insulin, C-peptide and proinsulin. Radiological investigation showed a tumour at the tail of the pancreas and the diagnosis was insulinoma. A spleen-preserving distal pancreatectomy was performed and the hypoglycaemic symptoms resolved. Immediately following the pancreatectomy, methotrexate was stopped and the patient's psoriasis went into remission. During a 2-year follow-up, she has required only minimal topical treatment for her skin.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Field S,Kelly G,Tobin AM,Barragry JM,Conlon KC,Kirby Bdoi
10.1111/j.1365-2230.2007.02578.xsubject
Has Abstractpub_date
2008-03-01 00:00:00pages
145-7issue
2eissn
0307-6938issn
1365-2230pii
CED2578journal_volume
33pub_type
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