Naevoid hypertrichosis--report of a patient with multiple lesions.

abstract：:The precursor protein proopiomelanocortin (POMC) produces many biologically active peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and beta-endorphin. The gene for alpha-MSH is encoded for by the POMC gene, but alpha-MSH c...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-05-01 00:00:00

abstract：:Encephalocraniocutaneous lipomatosis, or Haberland syndrome, is a rare congenital neurocutaneous disease. It is characterized clinically by unilateral lipomatous hamartomata of the scalp, eyelid, and outer globe of the eye, ipsilateral porencephalic cysts with cortical atrophy, cranial asymmetry, marked developmental ...

journal_title：Clinical and experimental dermatology

authors： Rubegni P,Risulo M,Sbano P,Buonocore G,Perrone S,Fimiani M

更新日期：2003-07-01 00:00:00

abstract：:We describe the challenging case of a patient presenting with extensive, eruptive mid-facial squamous cell carcinomas (SCCs) and keratoacanthomas (KAs) consequent to radiotherapy. Our patient had a personal and family history of multiple KAs and SCCs. Multiple self-healing squamous epithelioma, otherwise known as Ferg...

journal_title：Clinical and experimental dermatology

authors： Robertson SJ,Bashir SJ,Pichert G,Robson A,Whittaker S

更新日期：2010-06-01 00:00:00

abstract：:Histology sections from 61 cases of squamous cell carcinoma (SCC) of the vulva presenting after 1988 were reviewed for evidence of associated epithelial abnormality. Of the 50 patients with epithelium adjacent to the tumour, 24 had histological evidence of lichen sclerosus (LS), 20 of severe vulvar intraepithelial neo...

journal_title：Clinical and experimental dermatology

authors： Zaki I,Dalziel KL,Solomonsz FA,Stevens A

更新日期：1996-09-01 00:00:00

abstract：:It is a common experience that many Spitz naevi deviate from the idealized or stereotypical representation found in the literature, often causing considerable difficulties in distinguishing them from melanoma. The diagnostic term 'atypical Spitz naevus' is used to describe lesions that deviate from the typical appeara...

journal_title：Clinical and experimental dermatology

authors： de Giorgi V,Sestini S,Massi D,Papi F,Lotti T

更新日期：2008-05-01 00:00:00

abstract：:Three children (two boys and one girl) from the same family presented with photosensitivity, hyperpigmentation, hypertrichosis, mild skin fragility, blistering and scarring in childhood. On examination, the cutaneous lesions were found to have improved since their previous examinations. Laboratory tests showed raised ...

journal_title：Clinical and experimental dermatology

authors： Remenyik E,Lecha M,Badenas C,Kószó F,Vass V,Herrero C,Varga V,Emri G,Balogh A,Horkay I

更新日期：2008-08-01 00:00:00

abstract：:This paper reports a unique case of coexistence of vitiligo vulgaris, lichen planus and psoriasis vulgaris in a 53-year-old man. Five years after the onset of vitiligo, lichen planus developed on his lower lip. Another 4 years after the onset of lichen planus, he also exhibited psoriasis on his upper arms and trunk. B...

journal_title：Clinical and experimental dermatology

authors： Ujiie H,Sawamura D,Shimizu H

更新日期：2006-05-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease originating from the pilosebaceous unit, in which patients develop painful abscesses, sinus tracts, nodules and scarring, typically in intertriginous areas. Major gaps in our understanding of HS exist, and these may be partially due to the lack of an...

journal_title：Clinical and experimental dermatology

authors： Quartey QQ,Miller RJ,Pinsker BL,Okoh UJ,Shipman WD,George BA,Nwizu CC,Barnes LA,Kerns ML,Caffrey JA,Aliu O,Brown ID,Succaria F,Maynard JP,Herbert AS,Kang S,Miller LS,Okoye GA,Byrd AS

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease caused by genetic and epigenetic factors. There are conflicting results in the literature about the association between psoriasis and the methylenetetrahydrofolate reductase gene (MTHFR), ranging from strong linkage to no association. AIM:To investigat...

journal_title：Clinical and experimental dermatology

authors： Kilic S,Ozdemir O,Silan F,Isik S,Yildiz O,Karaagacli D,Silan C,Ogretmen Z

更新日期：2017-01-01 00:00:00

abstract：:Lupus miliaris disseminatus faciei (LMDF) is a chronic and uncommon inflammatory dermatosis, characterized by yellowish-red papules, especially on the face and around the eyelids. It is considered to be a reaction to destroyed hair follicles. We dermoscopically evaluated two patients diagnosed with LMDF. Dermoscopy re...

journal_title：Clinical and experimental dermatology

authors： Ayhan E,Alabalik U,Avci Y

更新日期：2014-06-01 00:00:00

abstract：:We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

journal_title：Clinical and experimental dermatology

authors： Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

更新日期：2000-01-01 00:00:00

abstract：:This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It provides a summary of key findings from 15 systematic reviews that were published during 2015, and focuses on the epidemiology and methodology issues ...

journal_title：Clinical and experimental dermatology

authors： Davies E,Rogers NK,Lloyd-Lavery A,Grindlay DJC,Thomas KS

更新日期：2018-06-01 00:00:00

abstract：:We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely pos...

journal_title：Clinical and experimental dermatology

authors： Palmer RA,Tran D,Hepburn NC,Ashton RE

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Multipotent cells can be isolated from dermis, and have wound-healing and antioxidant effects on human and murine skin. AIM:To investigate the changes in aged dermis after injection of dermal multipotent cells and adult fibroblasts. METHODS:Dermal multipotent cells were isolated and cultured from 3-day-old...

journal_title：Clinical and experimental dermatology

authors： Xue S,Li L

更新日期：2011-10-01 00:00:00

abstract：:The literature reveals what little is known about nutritional factors and hair loss. What we do know emanates from studies in protein-energy malnutrition, starvation, and eating disorders. In otherwise healthy individuals, nutritional factors appear to play a role in subjects with persistent increased hair shedding. H...

journal_title：Clinical and experimental dermatology

authors： Rushton DH

更新日期：2002-07-01 00:00:00

abstract：:The incidence of nonmelanoma skin cancer is significantly increased in recipients of solid-organ transplants. Photodynamic therapy (PDT) is a well-documented treatment option for superficial and selected nodular basal cell carcinomas (BCCs) in immunocompetent patients, but there are few reports describing PDT of BCCs ...

journal_title：Clinical and experimental dermatology

authors： Guleng GE,Helsing P

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Numerous studies have associated HS with obesity, and recently with metabolic syndrome (MetS). Both obesity and MetS are linked with metabolic changes. Thyroid hormones play a central role in metabolism and exert pleiotropic effects on adipogen...

journal_title：Clinical and experimental dermatology

authors： Miller IM,Vinding G,Sørensen HA,Rytgaard H,Mogensen UB,Ellervik C,Jemec GB

更新日期：2018-12-01 00:00:00

abstract：:Alopecia areata (AA) is a recurrent, immune-mediated, hair-loss disorder. It is associated with other autoimmune disorders that carry a high risk of cardiovascular disease (CVD). However, there is a lack of reports on the association of cardiovascular comorbidities and AA. Cardiac troponin I is a biomarker of myocardi...

journal_title：Clinical and experimental dermatology

authors： El-Sayed Mahmoud Marie R,El-Sayed GAK,Attia FM,Gomaa AHA

更新日期：2021-01-01 00:00:00

abstract：:Dermatologists performing surgical procedures face occupational and health hazards when exposed to surgical plume released during electrosurgical and ablative laser procedures. These hazardous fumes have toxic, infectious and carcinogenic effects. Understanding this risk is of particular importance during the COVID-19...

journal_title：Clinical and experimental dermatology

authors： Searle T,Ali FR,Al-Niaimi F

更新日期：2020-10-01 00:00:00

abstract：:We report a man with a 3-year-history of a striking eruption of small, 2-3 mm diameter keratotic, crateriform papules distributed symmetrically over the lower limbs. Morphologically the individual papules closely resembled those described in acrokeratoelastoidosis (AK) of Costa and in focal acral hyperkeratosis of Dow...

journal_title：Clinical and experimental dermatology

authors： Helbling I,Tucker SC,Chalmers RJ

更新日期：2001-05-01 00:00:00

abstract：:A 78-year-old Caucasian woman developed Sweet's syndrome which progressed over 3 weeks to pyoderma gangrenosum and subcorneal pustule formation. In spite of treatment the patient died and post-mortem examination revealed cryptogenic cirrhosis which could have explained the spectrum of neutrophilic skin disease observe...

journal_title：Clinical and experimental dermatology

authors： Davies MG,Hastings A

更新日期：1991-07-01 00:00:00

abstract：:We describe the results of a single-centre, double-blind, vehicle-controlled, parallel group study on the quantitative effects of 2% fusidic acid lotion (Fucidin lotion) in facial acne vulgaris. The trial was completed by 52 patients aged 15-25 years with mild to moderate acne who had been randomized to either Fucidin...

journal_title：Clinical and experimental dermatology

authors： Sommer S,Bojar R,Cunliffe WJ,Holland D,Holland KT,Naags H

更新日期：1997-09-01 00:00:00

abstract：:A whole array of cutaneous syndromes is associated with distinct dominant mutations in GJB2 encoding the gap junction protein connexin 26 (C x 26), including Vohwinkel's syndrome and keratitis-ichthyosis-deafness syndrome. In contrast, recessive GJB2 mutations occur in a large proportion of individuals with hearing lo...

journal_title：Clinical and experimental dermatology

authors： Common JE,Bitner-Glindzicz M,O'Toole EA,Barnes MR,Jenkins L,Forge A,Kelsell DP

更新日期：2005-11-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomas is an autosomal dominant condition that results in benign smooth muscle tumours of the skin and, in females, uterine fibroids. This syndrome overlaps with hereditary leiomyomatosis and renal cell cancer syndrome in which affected individuals may develop the rare type II papill...

journal_title：Clinical and experimental dermatology

authors： Chan I,Wong T,Martinez-Mir A,Christiano AM,McGrath JA

更新日期：2005-01-01 00:00:00

abstract：:Melkersson-Rosenthal syndrome (MRS) is an uncommon, complex neuromucocutaneous disorder characterized by recurrent orofacial oedema, facial palsy and fissured tongue. Complete MRS is uncommon. A case of complete MRS with multiple cranial nerve palsies is reported. ...

journal_title：Clinical and experimental dermatology

authors： Zeng W,Geng S,Niu X,Yuan J

更新日期：2010-04-01 00:00:00

abstract：:The linear pattern of lichen planus (LP) is extremely rare. In six publications 1256 patients with LP have been reviewed and only three cases of linear LP (LLP) are reported. The differential diagnosis of LLP includes a number of linear dermatoses in particular lichen striatus (LS) and the extent of overlap between th...

journal_title：Clinical and experimental dermatology

authors： Herd RM,McLaren KM,Aldridge RD

更新日期：1993-07-01 00:00:00

abstract：:Twenty-six men who presented with male pattern baldness (androgen-dependent alopecia), were quantitatively evaluated for scalp hair variables and compared with 13 age-matched controls. Compared to controls, significant mean differences for hair variables were found in the frontal-vertex area, while in the occipital ar...

journal_title：Clinical and experimental dermatology

authors： Rushton DH,Ramsay ID,Norris MJ,Gilkes JJ

更新日期：1991-05-01 00:00:00

abstract：:Nail involvement is estimated to affect 80-90% of patients with psoriasis at some point in their lives and is often associated with severe disease. Patients with nail involvement experience pain, functional impairment and social stigma, with significant restriction of daily activities and quality of life. Nail psorias...

journal_title：Clinical and experimental dermatology

authors： Thomas L,Azad J,Takwale A

更新日期：2021-01-01 00:00:00

abstract：:A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...

journal_title：Clinical and experimental dermatology

authors： Archer CB,Elias PM,Lowe NJ,Griffiths WA

更新日期：1989-07-01 00:00:00

abstract：:Topical application of leukotriene-B4 (LTB4) on normal skin has been used as an in-vivo model to investigate cutaneous inflammation and epidermal proliferation, which are important phenomena in the pathogenesis of psoriasis. The aim of the present investigation is to further elucidate the interrelation between inflamm...

journal_title：Clinical and experimental dermatology

authors： de Jong EM,van Erp PE,van Vlijmen IM,van de Kerkhof PC

更新日期：1992-11-01 00:00:00