Lessons learned from the development of a hidradenitis suppurativa xenograft mouse model.

abstract：BACKGROUND:Haemangioma of infancy (HOI) is the most frequently occurring benign tumour of infancy. A good, reliable and objective scoring system for haemangioma activity is not yet available. AIM:We have developed a simple system called the Haemangioma Activity Score (HAS) for scoring the (disease) proliferative activ...

journal_title：Clinical and experimental dermatology

authors： Janmohamed SR,de Waard-van der Spek FB,Madern GC,de Laat PC,Hop WC,Oranje AP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). AIM:To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. METHODS:In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched ...

journal_title：Clinical and experimental dermatology

authors： Ucuz I,Altunisik N,Sener S,Turkmen D,Kavuran NA,Marsak M,Colak C

更新日期：2020-02-16 00:00:00

abstract：BACKGROUND:Mortality from malignant melanoma (MM) has increased in Chile in the past decade. The location of MM lesions on the body has been correlated with prognosis and survival. AIM:To review body site and gender relationships with histopathologically confirmed primary MM in Chile. METHODS:Records of 575 cases pre...

journal_title：Clinical and experimental dermatology

authors： Zemelman V,Roa J,Tagle SR,Valenzuela CY

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Multipotent cells can be isolated from dermis, and have wound-healing and antioxidant effects on human and murine skin. AIM:To investigate the changes in aged dermis after injection of dermal multipotent cells and adult fibroblasts. METHODS:Dermal multipotent cells were isolated and cultured from 3-day-old...

journal_title：Clinical and experimental dermatology

authors： Xue S,Li L

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Interferons are molecules with antiviral effects, which have been used for the treatment of verruca for many years. AIMS:To determine if sublesional interferon (IFN)-alpha injection offers an effective alternative treatment for common warts. METHODS:We compared the results of single-dose sublesional IFN ap...

journal_title：Clinical and experimental dermatology

authors： Aksakal AB,Ozden MG,Atahan C,Onder M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Androgenic alopecia is known to be androgen-dependent. Insulin is found in hair follicles and may play a role in the regulation of androgen metabolism and the hair-growth cycle. OBJECTIVES:To compare the insulin resistance between people with androgenic alopecia and a control group. METHODS:A case-control ...

journal_title：Clinical and experimental dermatology

authors： Nabaie L,Kavand S,Robati RM,Sarrafi-Rad N,Kavand S,Shahgholi L,Meshkat-Razavi G

更新日期：2009-08-01 00:00:00

abstract：:Knowledge of the physiology of wound healing, in particular the recovery of the dermal and epidermal compartments and the co-ordination of these processes by the cytokine network, is of great importance to rational wound management. The individual components of the wound healing process have been studied using various...

journal_title：Clinical and experimental dermatology

authors： Van de Kerkhof PC,Van Bergen B,Spruijt K,Kuiper JP

更新日期：1994-09-01 00:00:00

abstract：:Pityriasis rotunda (PR) is an uncommon chronic dermatosis, which may be idiopathic or may be associated with infections or malignancy. We describe the clinical and biochemical findings of two patients with multiple myeloma, who were incidentally diagnosed with PR, and detail the clinical conditions with which this rar...

journal_title：Clinical and experimental dermatology

authors： van Heerden T,Webb MJ,Barrett CL

更新日期：2014-08-01 00:00:00

abstract：:We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarrin...

journal_title：Clinical and experimental dermatology

authors： Goh BK,Common JE,Gan WH,Kumarasinghe P

更新日期：2009-04-01 00:00:00

abstract：:Advances in molecular diagnostics have led to the feasibility of DNA-based prenatal testing in families at risk for recurrence of severe forms of both dystrophic and junctional epidermolysis bullosa. In this report, we describe prenatal testing in a woman who previously had a child affected with Herlitz junctional epi...

journal_title：Clinical and experimental dermatology

authors： Fassihi H,Ashton GH,Denyer J,Mellerio JE,Mason G,McGrath JA

更新日期：2005-03-01 00:00:00

abstract：:The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

journal_title：Clinical and experimental dermatology

authors： Norris P,Bacon K,Bird C,Hawk J,Camp R

更新日期：1999-07-01 00:00:00

abstract：:Steatocystoma multiplex is a rare, autosomal dominant condition characterized by multiple cysts, usually arising on the trunk and proximal extremities at puberty. We present two unrelated women with sporadic steatocystoma multiplex strictly confined to the vulva and arising at an older age. These cases represent an un...

journal_title：Clinical and experimental dermatology

authors： Rongioletti F,Cattarini G,Romanelli P

更新日期：2002-09-01 00:00:00

abstract：:Two patients presented with the unusual condition of multiple warty dyskeratomas on the scalp. Biopsies of affected skin stained positive with human keratin monoclonal antibodies HKN-6 and -7, specific for cortex and inner root sheath of normal human hair, respectively. Multiple warty dyskeratomas are a rare occurrenc...

journal_title：Clinical and experimental dermatology

authors： Griffiths TW,Hashimoto K,Sharata HH,Ellis CN

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Regulatory T cells (Tregs), together with tolerogenic dendritic cells (tDCs) are involved in maintaining peripheral tolerance. A recent report suggested both Tregs and tDCs may be pathogenic in granulomatous skin disorders. AIM:To examined the expression of CD39 on granuloma-composing cells and Foxp3-positi...

journal_title：Clinical and experimental dermatology

authors： Fujimura T,Kambayashi Y,Aiba S

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) occurs in 10-25% of unselected patients starting highly active antiretroviral therapy (HAART). About 52-78% of these cases involve cutaneous features. AIM:To describe the prevalence and incidence of new dermatological conditions within 6 months of patients ...

journal_title：Clinical and experimental dermatology

authors： Osei-Sekyere B,Karstaedt AS

更新日期：2010-07-01 00:00:00

abstract：:We describe a patient with intermittent unilateral hyperhidrosis localized to the left hand only. Histology confirmed the presence of an eccrine naevus. ...

journal_title：Clinical and experimental dermatology

authors： Parslew R,Lewis-Jones MS

更新日期：1997-09-01 00:00:00

abstract：:We present a case of erysipelas which complicated chronic discoid lupus erythematosus (CDLE) of the face. The diagnosis and implications for management are discussed. The changing epidemiology and clinical spectrum of erysipelas are reviewed. ...

journal_title：Clinical and experimental dermatology

authors： Keefe M,Wakeel RA,Kerr RE

更新日期：1989-01-01 00:00:00

abstract：:Previous studies on the association of smoking with acne vulgaris have reported conflicting results. The objective of this study was to investigate such an association. Our setting was three primary care practices in Hong Kong and one primary care practice in India. Patient characteristics in all four practices are si...

journal_title：Clinical and experimental dermatology

authors： Chuh AA,Zawar V,Wong WC,Lee A

更新日期：2004-11-01 00:00:00

abstract：:We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely pos...

journal_title：Clinical and experimental dermatology

authors： Palmer RA,Tran D,Hepburn NC,Ashton RE

更新日期：2001-01-01 00:00:00

abstract：:Xanthomas are important clinical manifestations of disordered lipid metabolism, which are mostly found in patients with familial hypercholesterolaemia (FH), an inherited disorder that is predominantly caused by mutations in the low-density lipoprotein receptor gene (LDLR). Tuberous and tendinous xanthomas with wide di...

journal_title：Clinical and experimental dermatology

authors： Kong MX,Zhang Q,Cao L,Zhao C,Ru GQ,Bi Q

更新日期：2015-10-01 00:00:00

abstract：:We report a case of white fibrous papulosis of the neck in a 70-year-old Iranian woman. To date this recently reported entity has only been described in Japanese patients. This asymptomatic eruption characteristically affects the posterior neck. The pale papules are round to oval 2-3 mm in diameter, and not follicular...

journal_title：Clinical and experimental dermatology

authors： Cerio R,Gold S,Jones EW

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM:To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS:The medical records of all the patients with p...

journal_title：Clinical and experimental dermatology

authors： Qiu Y,Ma G,Yang J,Hu X,Chen H,Jin Y,Lin X

更新日期：2013-12-01 00:00:00

abstract：:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. We report a case in which identical T-cell clones were identified in both patch and tumour stage lesions and in which the tumorous deposits, containing CD30-positive cells, regressed spontaneously. We discuss the differential diagnosis of the tumorou...

journal_title：Clinical and experimental dermatology

authors： Woodrow SL,Basarab T,Russell Jones R

更新日期：1996-09-01 00:00:00

abstract：:A 71-year-old woman with vitiligo developed multiple actinic keratoses only on the vitiligo skin of sun-exposed areas. She had worked outdoors as a farmer for a long period. Although actinic skin cancers arising on vitiligo skin have rarely been reported, the present case demonstrates that vitiligo skin is more suscep...

journal_title：Clinical and experimental dermatology

authors： Yashiro K,Nakagawa T,Takaiwa T,Inai M

更新日期：1999-05-01 00:00:00

abstract：:Sarcoidosis is a rare disease among children, manifesting differently in children below and above 4-5 years of age. Although the exact incidence and prevalence of childhood sarcoidosis is not known, the cutaneous involvement is frequent in both children and adults. Infiltration of old cutaneous scars with sarcoid gran...

journal_title：Clinical and experimental dermatology

authors： Singal A,Thami GP,Goraya JS

更新日期：2005-05-01 00:00:00

abstract：:Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intrig...

journal_title：Clinical and experimental dermatology

authors： Sethuraman G,Srinivas CR,D'Souza M,Thappa DM,Smiles L

更新日期：2002-09-01 00:00:00

abstract：:We describe the case of a 37-year-old female with a history of psoriasiform dermatitis who presented with multicentric primary cutaneous CD30-positive anaplastic large T cell lymphoma (ALCL). Despite aggressive systemic therapy, the patient suffered multiple relapses and the lymphoma spread to cervical and inguinal ly...

journal_title：Clinical and experimental dermatology

authors： Dawn G,Morrison A,Morton R,Bilsland D,Jackson R

更新日期：2003-11-01 00:00:00

abstract：:The precursor protein proopiomelanocortin (POMC) produces many biologically active peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and beta-endorphin. The gene for alpha-MSH is encoded for by the POMC gene, but alpha-MSH c...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-05-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomata (MCL) is an autosomal dominant disorder characterized by the development of benign smooth muscle tumours (leiomyomas) in the skin and uterus of affected women, and in the skin of affected men. In rare cases, MCL has been associated with a predisposition to the rare type II pa...

journal_title：Clinical and experimental dermatology

authors： Chuang GS,Martinez-Mir A,Engler DE,Gmyrek RF,Zlotogorski A,Christiano AM

更新日期：2006-01-01 00:00:00

abstract：:This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It provides a summary of key findings from 15 systematic reviews that were published during 2015, and focuses on the epidemiology and methodology issues ...

journal_title：Clinical and experimental dermatology

authors： Davies E,Rogers NK,Lloyd-Lavery A,Grindlay DJC,Thomas KS

更新日期：2018-06-01 00:00:00