Giant combined dermatofibroma with satellitosis.

abstract：BACKGROUND:The dorsum of the hand is a common site for squamous cell carcinoma, and excision with appropriate margins often results in surgical defects that cannot be repaired by primary side-to-side closure. AIM:To assess healing time, complications and resulting scars when surgical wounds on the dorsum of the hand w...

journal_title：Clinical and experimental dermatology

authors： Lateo SA,Langtry JA

更新日期：2013-08-01 00:00:00

abstract：:Treatment of autoimmune blistering diseases consists of systemic glucocorticosteroids usually in combination with additional immunosuppressants such as azathioprine and mycophenolate mofetil or immunomodulators such as dapsone, antibiotics, intravenous immunoglobulins, and immunoadsorption. In some patients, these tre...

journal_title：Clinical and experimental dermatology

authors： Schmidt E,Hunzelmann N,Zillikens D,Bröcker EB,Goebeler M

更新日期：2006-07-01 00:00:00

abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

journal_title：Clinical and experimental dermatology

authors： English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

更新日期：2011-03-01 00:00:00

abstract：:This article forms part of a series of annual updates that summarizes the evidence base for atopic eczema (AE). It provides a summary of key findings from 28 systematic reviews that were published or indexed during 2017, and focuses on the epidemiology, aetiology and risk factors of AE. AE is the largest single contri...

journal_title：Clinical and experimental dermatology

authors： Hale G,Davies E,Grindlay DJC,Rogers NK,Harman KE

更新日期：2019-12-01 00:00:00

abstract：:A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...

journal_title：Clinical and experimental dermatology

authors： Happle R

更新日期：2009-10-01 00:00:00

abstract：:We report a case of a 56-year-old woman who presented with a severe exacerbation of psoriasis with concurrent hypoglycaemic episodes. Methotrexate 17.5 mg weekly was required to control her psoriasis. Investigation of her hypoglycaemia showed raised levels of insulin, C-peptide and proinsulin. Radiological investigati...

journal_title：Clinical and experimental dermatology

authors： Field S,Kelly G,Tobin AM,Barragry JM,Conlon KC,Kirby B

更新日期：2008-03-01 00:00:00

abstract：:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica of...

journal_title：Clinical and experimental dermatology

authors： Owen CM,Murphy H,Yates VM

更新日期：2001-03-01 00:00:00

abstract：:The Langerhans cells in the lentigines of four patients with the Leopard syndrome contained large membrane bound accumulations of melanin granules. Giant melanosomes were only seen in two patients. The patients had no immune-based symptoms relating to their lentigines. The Leopard Syndrome, also known as multiple lent...

journal_title：Clinical and experimental dermatology

authors： Fryer PR,Pope FM

更新日期：1992-01-01 00:00:00

abstract：:Acute generalized exanthematous pustulosis (AGEP) is an uncommon disease, which presents as a nonfollicular erythematous sterile pustular eruption. More than 90% of the cases are induced by adverse drug reactions, often triggered by anti-infectious systemic drugs. We report a case of itraconazole-induced AGEP in a 22-...

journal_title：Clinical and experimental dermatology

authors： Cançado GG,Fujiwara RT,Freitas PA,Correa-Oliveira R,Bethony JM

更新日期：2009-12-01 00:00:00

abstract：:Identification of mutations in the hairless (HR) gene in patients with atrichia with papular lesions (APL) has proven of critical importance, as it provides a basis for the differentiation between APL and alopecia universalis. The establishment of the diagnostic criteria for APL has triggered the identification of a l...

journal_title：Clinical and experimental dermatology

authors： Massé M,Martinez-Mir A,Lam H,Geraghty MT,Christiano AM

更新日期：2005-07-01 00:00:00

abstract：:Endemic pemphigus foliaceus (EPF) is an autoimmune disease, which occurs in Brazil and other regions of South America. Mannose-binding lectin (MBL) and MBL-associated serine protease (MASP-2) play a key role in innate immunity, and its deficiency has been related to increased susceptibility to infection and autoimmune...

journal_title：Clinical and experimental dermatology

authors： Messias-Reason I,Bosco DG,Nisihara RM,Jakobsen LH,Petzl-Erler ML,Jensenius JC

更新日期：2008-07-01 00:00:00

abstract：:We describe the results of a single-centre, double-blind, vehicle-controlled, parallel group study on the quantitative effects of 2% fusidic acid lotion (Fucidin lotion) in facial acne vulgaris. The trial was completed by 52 patients aged 15-25 years with mild to moderate acne who had been randomized to either Fucidin...

journal_title：Clinical and experimental dermatology

authors： Sommer S,Bojar R,Cunliffe WJ,Holland D,Holland KT,Naags H

更新日期：1997-09-01 00:00:00

abstract：:Loceryl nail lacquer was developed to provide the effective antifungal drug, amorolfine, in a once-weekly dosage regimen combined with a convenient mode of application. Traditional formulations such as creams and nail solutions do not fulfil these requirements because they are wiped or washed off very rapidly. Amorolf...

journal_title：Clinical and experimental dermatology

authors： Pittrof F,Gerhards J,Erni W,Klecak G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) and lentigo maligna melanoma (LMM) can be difficult to manage surgically. Predetermined margins can be inadequate because of subclinical spread, or can affect function when margins are adjacent to the eye or mouth. AIM:To describe our 5-year experience in Nottingham of using the staged ...

journal_title：Clinical and experimental dermatology

authors： Patel AN,Perkins W,Leach IH,Varma S

更新日期：2014-07-01 00:00:00

abstract：:The case of an 80-year-old woman who developed extensive cutaneous calcification following intravenous phosphate administration is presented. Also the circumstances under which cutaneous calcification may occur are discussed. ...

journal_title：Clinical and experimental dermatology

authors： Mills CM,Knight AG

更新日期：1993-07-01 00:00:00

abstract：:We report the case of a 26-year-old man with haemophilia B and human immunodeficiency virus infection (HIV) who presented with a short history of multiple dermatofibromas. He also had troublesome psoriasis for which he was receiving acitretin with UVB therapy and had recently discontinued low-dose daily prednisolone f...

journal_title：Clinical and experimental dermatology

authors： Armstrong DK,Irvine A,Walsh MY,Mayne EE,Burrows D

更新日期：1995-11-01 00:00:00

abstract：:Acquired reactive perforating collagenosis (ARPC) is an uncommon dermatosis characterized by transepidermal elimination of altered collagen. It is commonly seen in patients with diabetes mellitus and/or chronic renal insufficiency. Rarely, it has been reported in association with malignancy and other conditions. We re...

journal_title：Clinical and experimental dermatology

authors： Yazdi S,Saadat P,Young S,Hamidi R,Vadmal MS

更新日期：2010-03-01 00:00:00

abstract：:Thalidomide has been used as an effective treatment for prurigo nodularis (PN) with a median dose of 200 mg, but the risk of peripheral neuropathy precludes long-term use. We analysed the efficacy of low-dose thalidomide (< 100 mg) in 17 patients with recalcitrant PN. Patients were initiated on thalidomide 50 mg on al...

journal_title：Clinical and experimental dermatology

authors： Sardana K,Gupta A,Sinha S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Interferons are molecules with antiviral effects, which have been used for the treatment of verruca for many years. AIMS:To determine if sublesional interferon (IFN)-alpha injection offers an effective alternative treatment for common warts. METHODS:We compared the results of single-dose sublesional IFN ap...

journal_title：Clinical and experimental dermatology

authors： Aksakal AB,Ozden MG,Atahan C,Onder M

更新日期：2009-01-01 00:00:00

abstract：:Ichthyosis hystrix, Curth-Macklin type (IHCM) is an extremely rare autosomal dominant dermatosis caused by mutations in the keratin genes, KRT1 or KRT10, which often manifests as extensive, dark, spiky or verrucous plaques and severe palmoplantar keratoderma. We report a novel frameshift truncation mutation, c.1596_15...

journal_title：Clinical and experimental dermatology

authors： Yang Z,Xu Z,Zhang N,Ma L

更新日期：2020-08-01 00:00:00

abstract：:Divided or kissing naevi are located on adjacent parts of the body that are separated during embryogenesis. Divided naevus of the penis (DNP) is exceedingly rare, with < 15 cases reported in the English language literature. Divided penile naevi affect the glans penis and inner foreskin, which are anatomical structures...

journal_title：Clinical and experimental dermatology

authors： Mendes CP,Samorano LP,Alessi SS,Nico MM

更新日期：2014-08-01 00:00:00

abstract：:The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne th...

journal_title：Clinical and experimental dermatology

authors： Martin AR,Lookingbill DP,Botek A,Light J,Thiboutot D,Girman CJ

更新日期：2001-07-01 00:00:00

abstract：:A patient with primary malignant melanoma localized to the right gluteal region is described. Four years later and after intercurrent influenza, disseminated metastases of malignant melanoma to the skin occurred. After a further 6 months melanodermia developed and lasted until the death of the patient (6 months later)...

journal_title：Clinical and experimental dermatology

authors： Péc J,Plank L,Mináriková E,Palencárová E,Rollová Y,Lazárová Z,Auxtová S,Lauko L

更新日期：1993-09-01 00:00:00

abstract：:Steatocystoma multiplex is a rare, autosomal dominant condition characterized by multiple cysts, usually arising on the trunk and proximal extremities at puberty. We present two unrelated women with sporadic steatocystoma multiplex strictly confined to the vulva and arising at an older age. These cases represent an un...

journal_title：Clinical and experimental dermatology

authors： Rongioletti F,Cattarini G,Romanelli P

更新日期：2002-09-01 00:00:00

abstract：:A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...

journal_title：Clinical and experimental dermatology

authors： Archer CB,Elias PM,Lowe NJ,Griffiths WA

更新日期：1989-07-01 00:00:00

abstract：:Postinflammatory hypopigmentation is a common cause of acquired hypopigmentary disorders. It can be a result of cutaneous inflammation, injury or dermatological treatment. There are also many specific conditions that present with hypopigmentation other than postinflammatory hypopigmentation. Most cases of postinflamma...

journal_title：Clinical and experimental dermatology

authors： Vachiramon V,Thadanipon K

更新日期：2011-10-01 00:00:00

abstract：:We report the case of a 46-year-old Indian woman who developed a hyperimmune response to a typhoid booster injection in association with the development of pemphigus vulgaris. To our knowledge, this association has not previously been reported. ...

journal_title：Clinical and experimental dermatology

authors： Bellaney GJ,Rycroft RJ

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Both leprosy and human immunodeficiency virus (HIV) are infectious diseases, and are an important global health problem. Patients with leprosy who are co-infected with HIV seem to be at higher risk of developing leprosy reactions. AIM:To examine the histological features of leprosy in patients with HIV and ...

journal_title：Clinical and experimental dermatology

authors： Deps P,Lucas S,Porro AM,Maeda SM,Tomimori J,Guidella C,Reuter T,Oliveira NS,Madureira BP,Souza VA,Loureiro RM,Alves BL,Bellone A,Lockwood DN

更新日期：2013-07-01 00:00:00

abstract：:Desmoplastic trichoepithelioma (DT) is a rare benign adnexal neoplasm considered to have follicular differentiation. It usually presents as an asymptomatic, firm, annular plaque with a raised border. The most common site of occurrence is the face, usually on the cheek. Females are more often affected than males and th...

journal_title：Clinical and experimental dermatology

authors： Carter JJ,Kaur MR,Hargitai B,Brown R,Slator R,Abdullah A

更新日期：2007-09-01 00:00:00

abstract：:Clear cell acanthoma (CCA) is a benign epidermal tumour with distinctive and uniform clinical and histological features. Although solitary lesions are the rule, some cases of multiple CCA, rarely with more than 10 lesions, have been previously reported. Only 22 cases of multiple CCA have been described in the English ...

journal_title：Clinical and experimental dermatology

authors： Innocenzi D,Barduagni F,Cerio R,Wolter M

更新日期：1994-05-01 00:00:00