Abstract:
:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica often proves very resistant to treatment. We report a case of a 44-year-old woman with ulcerated necrobiosis lipoidica that healed following grafting with a tissue-engineered living dermal tissue.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Owen CM,Murphy H,Yates VMdoi
10.1046/j.1365-2230.2001.00789.xkeywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
176-8issue
2eissn
0307-6938issn
1365-2230pii
ced789journal_volume
26pub_type
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