Tissue-engineered dermal skin grafting in the treatment of ulcerated necrobiosis lipoidica.

Abstract:

:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica often proves very resistant to treatment. We report a case of a 44-year-old woman with ulcerated necrobiosis lipoidica that healed following grafting with a tissue-engineered living dermal tissue.

journal_name

Clin Exp Dermatol

authors

Owen CM,Murphy H,Yates VM

doi

10.1046/j.1365-2230.2001.00789.x

keywords:

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

176-8

issue

2

eissn

0307-6938

issn

1365-2230

pii

ced789

journal_volume

26

pub_type

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