Acquired reactive perforating collagenosis associated with papillary thyroid carcinoma: a paraneoplastic phenomenon?

Abstract:

:Acquired reactive perforating collagenosis (ARPC) is an uncommon dermatosis characterized by transepidermal elimination of altered collagen. It is commonly seen in patients with diabetes mellitus and/or chronic renal insufficiency. Rarely, it has been reported in association with malignancy and other conditions. We report a 30-year-old woman with insulin-dependent diabetes mellitus who presented with multiple, discrete, violaceous, hyperkeratotic papules on the extensor aspects of both legs, characteristic of ARPC. Four months later, metastatic papillary thyroid cancer was diagnosed. This case further supports the possibility that ARPC may represent a paraneoplastic phenomenon.

journal_name

Clin Exp Dermatol

authors

Yazdi S,Saadat P,Young S,Hamidi R,Vadmal MS

doi

10.1111/j.1365-2230.2009.03211.x

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

152-5

issue

2

eissn

0307-6938

issn

1365-2230

pii

CED3211

journal_volume

35

pub_type

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