The A/A genotype of an interleukin-17A polymorphism predisposes to increased severity of atopic dermatitis and coexistence with asthma.

abstract：:Pyostomatitis vegetans is a rare oral disorder often associated with gastrointestinal and/or cutaneous diseases and sometimes with other disorders. The association of pyostomatitis vegetans with inflammatory bowel disease, particularly ulcerative colitis, is well known and in most cases bowel disease precedes the onse...

journal_title：Clinical and experimental dermatology

authors： Hegarty AM,Barrett AW,Scully C

更新日期：2004-01-01 00:00:00

abstract：:A retrospective case series of 53 female patients with incontinentia pigmenti (IP) including 28 secondary cases (female relatives of probands) was reviewed and compared with other series in an attempt to estimate more accurately the true disease burden of patients with IP. We found that, while the frequency of the fir...

journal_title：Clinical and experimental dermatology

authors： Phan TA,Wargon O,Turner AM

更新日期：2005-09-01 00:00:00

abstract：:Acquired cold urticaria (ACU) is a frequent subtype of physical urticaria that is caused by the release of proinflammatory mast cell mediators after cold exposure. Although the underlying causes of ACU still remain to be clarified in detail, a wide range of diseases has been reported to be associated with ACU. This re...

journal_title：Clinical and experimental dermatology

authors： Siebenhaar F,Weller K,Mlynek A,Magerl M,Altrichter S,Vieira Dos Santos R,Maurer M,Zuberbier T

更新日期：2007-05-01 00:00:00

abstract：:Whole-body ultraviolet (UV)A1 (340-400 nm) phototherapy was first introduced 30 years ago, but is currently available in the UK in only three dermatology departments. A workshop to discuss UVA1 was held by the British Photodermatology Group in May 2009, the aim of which was to provide an overview of UVA1 phototherapy ...

journal_title：Clinical and experimental dermatology

authors： Kerr AC,Ferguson J,Attili SK,Beattie PE,Coleman AJ,Dawe RS,Eberlein B,Goulden V,Ibbotson SH,Menage Hdu P,Moseley H,Novakovic L,Walker SL,Woods JA,Young AR,Sarkany RP

更新日期：2012-04-01 00:00:00

abstract：:A family with pachyonychia congenita in which affected individuals showed nail involvement only is described. Pachyonychia congenita is a rare hereditary disorder inherited in an autosomal dominant manner. Various classifications of pachyonychia congenita have been suggested but none indicates nail involvement as a so...

journal_title：Clinical and experimental dermatology

authors： Pryce DW,Verbov JL

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Port-wine stains (PWS) are congenital capillary malformations that persist throughout life. Laser therapy is a common treatment for PWS, and pulsed-dye laser is the current treatment of choice. AIM:To compare the clinical results on untreated PWS of two dye lasers with different wavelengths and pulse durati...

journal_title：Clinical and experimental dermatology

authors： Frohm Nilsson M,Passian S,Wiegleb Edstrom D

更新日期：2010-03-01 00:00:00

abstract：:We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with pr...

journal_title：Clinical and experimental dermatology

authors： Perez A,Clements SE,Benton E,Robson A,Bhogal B,Stefanato CM,McGibbon D

更新日期：2009-12-01 00:00:00

abstract：:The effect of Anandron, a novel non-steroidal anti-androgen, on the reduction in sexual hair growth of 14 male-to-female transsexuals was investigated. Anandron (300 mg/day) alone for 8 weeks increased serum testosterone levels (mean: 19.2 +/- 6.1 to 44.9 +/- 11.5 mmol/l) and serum oestradiol levels (mean: 0.08 +/- 0....

journal_title：Clinical and experimental dermatology

authors： Asscheman H,Gooren LJ,Peereboom-Wynia JD

更新日期：1989-09-01 00:00:00

abstract：:A 34-year-old woman presented with 2-year history of a dome-shaped papule on a well-circumscribed, thickened, port-wine stain on the left side of the chin. Squeezing on the port-wine-stain plaque revealed many comedos within dilated follicular orifices. The papule was excised and submitted for histological examination...

journal_title：Clinical and experimental dermatology

authors： Yang CH,Shen SC,Yeh JT,Tsai YL,Hong HS

更新日期：2005-09-01 00:00:00

abstract：:Although surgery may be curative in early malignant melanoma, its effect on survival lessens with each succeeding stage of the disease. A wide variety of immunological strategies have therefore been used to improve the prognosis of patients with malignant melanoma, but adjuvant therapy with interferon (IFN)-alpha is t...

journal_title：Clinical and experimental dermatology

authors： Russell-Jones R

更新日期：2000-01-01 00:00:00

abstract：:We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarrin...

journal_title：Clinical and experimental dermatology

authors： Goh BK,Common JE,Gan WH,Kumarasinghe P

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Malignant melanoma (MM), accounts for around 10% of skin cancers. To date, there have been few data on patient satisfaction with initial management of MM. OBJECTIVE:To identify the predictors of patient satisfaction with initial diagnosis and management of MM. METHODS:Data on 214 patients were collected us...

journal_title：Clinical and experimental dermatology

authors： Sheth N,Sarker SJ,Harries M,Healy C,Russell-Jones R,Acland K

更新日期：2010-08-01 00:00:00

abstract：:Sera from 10 patients with seborrhoeic dermatitis and from 10 age-matched healthy individuals were examined for IgG activity against Pityrosporum ovale. The IgG activity was analysed using the following techniques: an enzyme-linked immunosorbent assay (ELISA) against whole P. ovale cells, purified cell-wall carbohydra...

journal_title：Clinical and experimental dermatology

authors： Bergbrant IM,Johansson S,Robbins D,Bengtsson K,Faergemann J,Scheynius A,Söderström T

更新日期：1991-09-01 00:00:00

abstract：:We report the cases of two patients who developed generalized pustular psoriasis on the withdrawal of oral Cyclosporin treatment for persistent palmoplantar pustulosis. This complication does not appear to have been reported previously. ...

journal_title：Clinical and experimental dermatology

authors： De Silva BD,Benton EC,Tidman MJ

更新日期：1999-01-01 00:00:00

abstract：:Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

journal_title：Clinical and experimental dermatology

authors： Jones SA,Black MM

更新日期：1997-03-01 00:00:00

abstract：:In primary localized cutaneous amyloid, deposition of amyloid is confined to the skin without the involvement of any internal organs. Amyloid deposition in the skin is often scanty, and electron microscopy may be needed to confirm the presence of the typical amyloid fibrils. There have been several case reports of cut...

journal_title：Clinical and experimental dermatology

authors： Macsween RM,Saihan EM

更新日期：1997-01-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomata (MCL) is an autosomal dominant disorder characterized by the development of benign smooth muscle tumours (leiomyomas) in the skin and uterus of affected women, and in the skin of affected men. In rare cases, MCL has been associated with a predisposition to the rare type II pa...

journal_title：Clinical and experimental dermatology

authors： Chuang GS,Martinez-Mir A,Engler DE,Gmyrek RF,Zlotogorski A,Christiano AM

更新日期：2006-01-01 00:00:00

abstract：:Stewart-Bluefarb syndrome (SBS) is a subtype of pseudo-Kaposi sarcoma (PKS), which is associated with congenital arteriovenous malformation. It is a rare syndrome, characterized by cutaneous lesions with onset in the second decade of life. We report a case of SBS in a 33-year-old man presenting with a 15-year history ...

journal_title：Clinical and experimental dermatology

authors： Verma SB,Vasani R

更新日期：2016-07-01 00:00:00

abstract：:A case of Bowen's disease is described in which striking quantities of amyloid were detected in the papillary dermis visualized easily by routine haematoxylin and eosin staining. The material showed positive labelling with an antikeratin monoclonal antibody consistent with the proposed origin of the amyloid as degener...

journal_title：Clinical and experimental dermatology

authors： Speight EL,Milne DS,Lawrence CM

更新日期：1993-05-01 00:00:00

abstract：:A 69-year-old woman presented with a nonhealing ulcer on her right cheek. On histological examination of a biopsy, no evidence of granuloma formation or malignancy was found, and the overall picture was felt to be consistent with dermatitis artefacta (DA). The patient was referred to a joint psychodermatology clinic, ...

journal_title：Clinical and experimental dermatology

authors： Lowry CL,Bewley A,Taylor R

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an organ-specific autoimmune disease characterized by folliculotropic T-cell infiltrates around anagen-stage hair follicles. The role of T helper (Th)1 and Th2 cytokines in the pathogenesis of AA have not been established. AIM:To determine whether serum cytokine profiles define the s...

journal_title：Clinical and experimental dermatology

authors： Barahmani N,Lopez A,Babu D,Hernandez M,Donley SE,Duvic M

更新日期：2010-06-01 00:00:00

abstract：:Melanoma-associated retinopathy (MAR) is a rare paraneoplastic autoimmune manifestation of cutaneous malignant melanoma. Patients classically present with acute onset night blindness, positive visual phenomena and visual field defects, and typically have significantly reduced quality of life as a result. Early recogni...

journal_title：Clinical and experimental dermatology

authors： Elsheikh S,Gurney SP,Burdon MA

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Cutis marmorata telangiectatica congenita (CMTC) is a congenital vascular anomaly of unknown aetiology. About 300 cases have been reported in the literature. The rate of associated anomalies varies between 20% and 70%. METHODS:We report a series of 27 children with CMTC, 18 of whom were followed-up prospect...

journal_title：Clinical and experimental dermatology

authors： Kienast AK,Hoeger PH

更新日期：2009-04-01 00:00:00

abstract：:Contact hypersensitivity from topical corticosteroids is becoming increasingly recognized; it is present in 2-5% of the patients attending contact dermatitis clinics. The use of a corticosteroid series containing tixocortal pivalate 1% (petrolatum), to detect hypersensitivity to hydrocortisone, and other steroids 1% (...

journal_title：Clinical and experimental dermatology

authors： Wilkinson SM

更新日期：1994-01-01 00:00:00

abstract：:A finger-tip unit (FTU) is the amount of ointment expressed from a tube with a 5 mm diameter nozzle, applied from the distal skin-crease to the tip of the index finger. Thirty adult-patients treated various anatomical regions using FTU's of ointment. The number of FTU's required was: face and neck 2.5 (s.d. +/- 0.8); ...

journal_title：Clinical and experimental dermatology

authors： Long CC,Finlay AY

更新日期：1991-11-01 00:00:00

abstract：:Drug reactions are common in HIV-1 disease, with the incidence having been reported to increase with increasing stage and with CD4+ T-cell counts below 200/microliters. However, there have been numerous reports of patients in which rechallenge, dosing changes or continued therapy have resulted in no recurrence or else...

journal_title：Clinical and experimental dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,Ng TH,Wagner KF

更新日期：1997-05-01 00:00:00

abstract：:Eleven cases of cutaneous B-cell lymphoma (CBCL) were studied. The ages at presentation ranged from 34 to 79 years (mean = 59.9 years). Six patients were female and five male. Five of the 11 patients had a solitary tumour and the other six had multiple tumours at initial presentation. According to Burg's classificatio...

journal_title：Clinical and experimental dermatology

authors： Nagatani T,Miyazawa M,Matsuzaki T,Hayakawa H,Iemoto G,Kim ST,Baba N,Aihara M,Miyamoto H,Nakajima H

更新日期：1993-11-01 00:00:00

abstract：:The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne th...

journal_title：Clinical and experimental dermatology

authors： Martin AR,Lookingbill DP,Botek A,Light J,Thiboutot D,Girman CJ

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Lichen planus (LP) is an inflammatory disease of the skin and mucous membranes. Autoimmunity has been suggested as a possible cause of this disease. The cyclooxygenase enzymes (COX-1, COX-2) are the key enzymes in the conversion of arachidonic acid into prostaglandins. Prostaglandin E2 (PGE2), a key product ...

journal_title：Clinical and experimental dermatology

authors： El-Rifaie AA,Rashed LA,Doss RW

更新日期：2015-12-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease affecting the skin folds. Multiple therapeutic options have been proposed for severe cases, but persistent responses are rarely seen. Important complications of HS are uncommon, and usually seen only in severe and unresponsive disease. Amyloid ...

journal_title：Clinical and experimental dermatology

authors： Utrera-Busquets M,Romero-Maté A,Castaño Á,Alegre L,García-Donoso C,Borbujo J

更新日期：2016-04-01 00:00:00