Bullous secondary syphilis.

abstract：BACKGROUND:In drug-induced toxic epidermal necrolysis (TEN), the epidermal destruction is associated with a slight to moderate lymphomonocytic cell infiltrate. Interleukin (IL)-8, which is a keratinocyte-derived pro-inflammatory cytokine, might be involved in this process. The IL-8 receptor CXCR2 has also been shown to...

journal_title：Clinical and experimental dermatology

authors： Paquet P,Ribbens C,Piérard GE

更新日期：2007-11-01 00:00:00

abstract：:Xanthomas are important clinical manifestations of disordered lipid metabolism, which are mostly found in patients with familial hypercholesterolaemia (FH), an inherited disorder that is predominantly caused by mutations in the low-density lipoprotein receptor gene (LDLR). Tuberous and tendinous xanthomas with wide di...

journal_title：Clinical and experimental dermatology

authors： Kong MX,Zhang Q,Cao L,Zhao C,Ru GQ,Bi Q

更新日期：2015-10-01 00:00:00

abstract：:A group of patients who attended dermatology clinics in Northern Ireland between 1960 and 1970 with a diagnosis of infantile acne was compared with a similar age-matched control group of 160 medical students. The severity of the acne was judged according to the form of treatment required--topical treatment, systemic a...

journal_title：Clinical and experimental dermatology

authors： Chew EW,Bingham A,Burrows D

更新日期：1990-09-01 00:00:00

abstract：:We report a case of toxic pustuloderma secondary to thalidomide in a patient with severe nodular prurigo. To our knowledge this is the first reported case. With the increasing use of thalidomide for a variety of dermatological conditions it is clearly important that this rare side-effect now be recognised. ...

journal_title：Clinical and experimental dermatology

authors： Darvay A,Basarab T,Russell-Jones R

更新日期：1997-11-01 00:00:00

abstract：:Chronic spontaneous urticaria (CSU) is a common and disabling skin disease which is often associated with psychiatric comorbidities such as anxiety and depression. These conditions are widely thought to cause, drive and/or maintain CSU, and have been reported as making an important contribution to the low quality of l...

journal_title：Clinical and experimental dermatology

authors： Weller K,Koti I,Makris M,Maurer M

更新日期：2013-12-01 00:00:00

abstract：:Photodynamic therapy (PDT) with topical 5-aminolaevulinic acid (5-ALA) is a promising new treatment for superficial malignant nonmelanoma tumours, including cutaneous malignant lymphoma. Here, we report a case of cutaneous anaplastic large cell lymphoma effectively treated by PDT with topical 5-ALA in combination with...

journal_title：Clinical and experimental dermatology

authors： Umegaki N,Moritsugu R,Katoh S,Harada K,Nakano H,Tamai K,Hanada K,Tanaka M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

journal_title：Clinical and experimental dermatology

authors： Yue X,Wang A,Sun Y,Li Q

更新日期：2018-12-01 00:00:00

abstract：:We report the occurrence of severe symptomatic bronchoconstriction in an atopic asthmatic subject following the application of coal tar bandages. Investigations showed that this was likely to have been caused by inhalation of coal tar vapour. We suggest that coal tar preparations should be used with caution in asthmat...

journal_title：Clinical and experimental dermatology

authors： Ibbotson SH,Stenton SC,Simpson NB

更新日期：1995-01-01 00:00:00

abstract：:Osteoporosis has been observed with chronic hypervitaminosis A, leading some authors to hypothesize that systemic retinoids may have an effect on bone mineral density. Two previous small studies identified osteoporosis in patients who received long-term therapy with etretinate. Etretinate has now been superceeded by a...

journal_title：Clinical and experimental dermatology

authors： McMullen EA,McCarron P,Irvine AD,Dolan OM,Allen GE

更新日期：2003-05-01 00:00:00

abstract：:We describe the challenging case of a patient presenting with extensive, eruptive mid-facial squamous cell carcinomas (SCCs) and keratoacanthomas (KAs) consequent to radiotherapy. Our patient had a personal and family history of multiple KAs and SCCs. Multiple self-healing squamous epithelioma, otherwise known as Ferg...

journal_title：Clinical and experimental dermatology

authors： Robertson SJ,Bashir SJ,Pichert G,Robson A,Whittaker S

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Several studies have shown that in Africa squamous cell carcinoma (SCC) is commoner than other skin malignancies. The risk factors are grouped generally into solar and nonsolar factors and their contributions vary with race, geographical region and site of lesion. This study attempted to identify risk factor...

journal_title：Clinical and experimental dermatology

authors： Asuquo ME,Udosen AM,Ikpeme IA,Ngim NE,Otei OO,Ebughe G,Bassey EE

更新日期：2009-12-01 00:00:00

abstract：:A 15-year-old boy with Kaposi's varicelliform eruption complicating healing second degree burns is reported. Clinically, umbilicated vesicles and pustules evolving to extensive erosions appeared over previously burned areas, sparing normal skin. Rapid diagnosis was made on the basis of the presence of multinucleate gi...

journal_title：Clinical and experimental dermatology

authors： Bartralot R,García-Patos V,Rodríguez-Cano L,Castells A

更新日期：1996-03-01 00:00:00

abstract：:We report the cases of two patients who developed generalized pustular psoriasis on the withdrawal of oral Cyclosporin treatment for persistent palmoplantar pustulosis. This complication does not appear to have been reported previously. ...

journal_title：Clinical and experimental dermatology

authors： De Silva BD,Benton EC,Tidman MJ

更新日期：1999-01-01 00:00:00

abstract：:The therapeutic use of the induction of an allergic contact sensitivity to diphencyprone in alopecia areata has been studied. Fourteen subjects had alopecia totalis and four had extensive and long-standing alopecia areata. Topical diphencyprone was capable of inducing an allergic contact sensitivity in 16 subjects (89...

journal_title：Clinical and experimental dermatology

authors： Monk B

更新日期：1989-03-01 00:00:00

abstract：:Familial occurrence of Jessner's lymphocytic infiltration of the skin is reported in a father and daughter. A definitive diagnosis of Jessner's disease was greatly facilitated by the presence of large numbers of plasmacytoid monocytes within the dermal infiltrates in both patients. A role for skin-directed lymphocyte ...

journal_title：Clinical and experimental dermatology

authors： Toonstra I,van der Putte SC,de la Faille HB,van Vloten WA

更新日期：1993-03-01 00:00:00

abstract：:IgA pemphigus is rare but may be underdiagnosed. We describe two cases, a 50-year-old female with a pustular eruption resembling subcorneal pustular dermatosis and a 55-year-old male with a pruritic vesiculopustular eruption simulating dermatitis herpetiformis. They illustrate the clinical heterogeneity of IgA pemphig...

journal_title：Clinical and experimental dermatology

authors： Harman KE,Holmes G,Bhogal BS,McFadden J,Black MM

更新日期：1999-11-01 00:00:00

abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

journal_title：Clinical and experimental dermatology

authors： English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

更新日期：2011-03-01 00:00:00

abstract：:Dystrophic epidermolysis bullosa (DEB) is caused by mutations in the COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils. The characteristic genetic lesion in dominant DEB (DDEB) is a glycine substitution in the collagenous domain of the protein. In this study, we identified a Chinese fami...

journal_title：Clinical and experimental dermatology

authors： Zhang XJ,Song YX,Zhang XQ,Yang S,Li M,Li CR,Yang CJ,Yang J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Artemisia scoparia Waldst. et Kitaib (AS) (Oriental wormwood, known as Bissuk in Korea) is a plant used in cosmetic and pharmaceutical treatments. However, the effect of AS on atopic dermatitis (AD) has not been described. AIM:To examine the inhibitory effect of AS on AD using a murine model. METHODS:We ap...

journal_title：Clinical and experimental dermatology

authors： Ryu KJ,Yoou MS,Seo Y,Yoon KW,Kim HM,Jeong HJ

更新日期：2018-10-01 00:00:00

abstract：:A case of pure non-epidermotropic cutaneous lymphoma in a human immunodeficiency virus-infected patient is reported following a viral opportunistic infection [cytomegalovirus (CMV) hepatitis]. The lymphoid infiltrate was Epstein-Barr virus and CMV negative with a CD30-positive T-cell phenotype. Molecular analysis demo...

journal_title：Clinical and experimental dermatology

authors： Viraben R,Brousset P,Aquilina C,Lamant L

更新日期：1997-11-01 00:00:00

abstract：:A patient with primary malignant melanoma localized to the right gluteal region is described. Four years later and after intercurrent influenza, disseminated metastases of malignant melanoma to the skin occurred. After a further 6 months melanodermia developed and lasted until the death of the patient (6 months later)...

journal_title：Clinical and experimental dermatology

authors： Péc J,Plank L,Mináriková E,Palencárová E,Rollová Y,Lazárová Z,Auxtová S,Lauko L

更新日期：1993-09-01 00:00:00

abstract：:A 69-year-old woman presented with a nonhealing ulcer on her right cheek. On histological examination of a biopsy, no evidence of granuloma formation or malignancy was found, and the overall picture was felt to be consistent with dermatitis artefacta (DA). The patient was referred to a joint psychodermatology clinic, ...

journal_title：Clinical and experimental dermatology

authors： Lowry CL,Bewley A,Taylor R

更新日期：2013-07-01 00:00:00

abstract：:Ninety-six patients with a clinical and parasitological diagnosis of cutaneous leishmaniasis were recruited to a comparative randomized clinical trial evaluating the efficacy of topical paromomycin vs. weekly intralesional injections of meglumine antimoniate. The patients were randomly divided into two treatment group...

journal_title：Clinical and experimental dermatology

authors： Faghihi G,Tavakoli-kia R

更新日期：2003-01-01 00:00:00

abstract：:Acquired dermal melanocytosis (ADM) is a relatively rare, but well-described disease among adolescent to middle-aged East Asian women, particularly those of Japanese and Chinese descent. Clinically, ADM manifests as multiple punctate and greyish-brown pigmented areas 1-3 mm in diameter occurring on both sides of the f...

journal_title：Clinical and experimental dermatology

authors： Ouchi T,Ishii K,Nishikawa T,Ishiko A

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Atopic eczema (AE) is characterized by reduced skin hydration (SH) and impaired integrity of the skin. Proper emollient usage is an important facet of AE management and patients are encouraged to use emollients liberally. AIM:To evaluate whether the amount of emollient and skin cleanser used correlates with...

journal_title：Clinical and experimental dermatology

authors： Hon KL,Ching GK,Leung TF,Choi CY,Lee KK,Ng PC

更新日期：2010-01-01 00:00:00

abstract：:Recent studies suggest that histamine H2-receptor antagonists may be useful in the treatment of urticaria. This study was conducted to determine whether famotidine, a H2 antagonist, is effective in the treatment of acute urticaria and compare its effect with that of the H1 antagonist diphenhydramine. In this prospecti...

journal_title：Clinical and experimental dermatology

authors： Watson NT,Weiss EL,Harter PM

更新日期：2000-05-01 00:00:00

abstract：:The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

journal_title：Clinical and experimental dermatology

authors： Norris P,Bacon K,Bird C,Hawk J,Camp R

更新日期：1999-07-01 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：:A 78-year-old Caucasian woman developed Sweet's syndrome which progressed over 3 weeks to pyoderma gangrenosum and subcorneal pustule formation. In spite of treatment the patient died and post-mortem examination revealed cryptogenic cirrhosis which could have explained the spectrum of neutrophilic skin disease observe...

journal_title：Clinical and experimental dermatology

authors： Davies MG,Hastings A

更新日期：1991-07-01 00:00:00

abstract：:A 68-year-old Caucasian male presented with a 5-week history of a widespread pruritic papular eruption. Histology from a papule on the left shoulder showed a dense dermal infiltrate of large mononuclear cells which were positive for leucocyte common antigen, KP1 and PGM1, with an MIB-1 proliferating fraction of 40%, d...

journal_title：Clinical and experimental dermatology

authors： Millard TP,Aitchison R,Wilkinson JD

更新日期：2003-03-01 00:00:00