Circulating miR-142-3p levels in patients with systemic sclerosis.

abstract：:Four patients presenting with chronic pigmented purpuric dermatosis (CPPD) on the limbs were found to have granulomatous inflammation superimposed on the pathological changes of CPPD. Three of the four patients had hyperlipidaemia. Therefore, the granulomatous reaction observed could be associated with hyperlipidaemia...

journal_title：Clinical and experimental dermatology

authors： Lin WL,Kuo TT,Shih PY,Lin WC,Wong WR,Hong HS

更新日期：2007-09-01 00:00:00

abstract：:Dapsone has potent anti-inflammatory effects, and is used in the treatment of leprosy, cutaneous vasculitis, neutrophilic dermatoses, and dermatitis herpetiformis and other blistering disorders. However, it may cause severe adverse reactions such as hypersensitivity syndrome, which is characterized by fever, skin rash...

journal_title：Clinical and experimental dermatology

authors： Chun JS,Yun SJ,Kim SJ,Lee SC,Won YH,Lee JB

更新日期：2009-12-01 00:00:00

abstract：:We report the case of a 28-year-old homosexual man with advanced HIV disease (CDC classification group IV A) who developed erythrodermic psoriasis which responded to calcipotriol, a topical vitamin D analogue. We believe this to be the first reported case of HIV-related psoriasis responsive to this form of treatment. ...

journal_title：Clinical and experimental dermatology

authors： Gray JD,Bottomley W,Layton AM,Cotterill JA,Monteiro E

更新日期：1992-09-01 00:00:00

abstract：:A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...

journal_title：Clinical and experimental dermatology

authors： Archer CB,Elias PM,Lowe NJ,Griffiths WA

更新日期：1989-07-01 00:00:00

abstract：:Two cases of localized multiple neurofibromas are reported. The patients had fairly large, closely grouped neurofibromas limited to a circumscribed part of the body, a very different clinical feature from segmental neurofibromatosis, but with otherwise had typical histopathological features. Possible aetiology is disc...

journal_title：Clinical and experimental dermatology

authors： Mohri S,Atsusaka K,Sasaki T

更新日期：1992-05-01 00:00:00

abstract：:In this study we used the nickel contact allergy patch (CAP) test to investigate the effect of topical corticosteroids on allergic contact dermatitis (ACD). On day 1, three CAP tests were applied for 48 h on the forearms of 20 female volunteers with a known nickel ACD. CAP of the right forearm contained 5% nickel, and...

journal_title：Clinical and experimental dermatology

authors： Hachem JP,De Paepe K,Vanpée E,Bogaerts M,Kaufman L,Rogiers V,Roseeuw D

更新日期：2002-01-01 00:00:00

abstract：:The Langerhans cells in the lentigines of four patients with the Leopard syndrome contained large membrane bound accumulations of melanin granules. Giant melanosomes were only seen in two patients. The patients had no immune-based symptoms relating to their lentigines. The Leopard Syndrome, also known as multiple lent...

journal_title：Clinical and experimental dermatology

authors： Fryer PR,Pope FM

更新日期：1992-01-01 00:00:00

abstract：:A 55-year-old diabetic female treated with a combination of a short- and intermediate-acting insulin, developed sterile furunculoid lesions at the injection sites which eventually healed with atrophic scars. Histopathologically, an initial neutrophilic stage was followed by granulomatous and fibrotic stages. It was co...

journal_title：Clinical and experimental dermatology

authors： Jordaan HF,Sandler M

更新日期：1989-05-01 00:00:00

abstract：:Pyostomatitis vegetans is a rare oral disorder often associated with gastrointestinal and/or cutaneous diseases and sometimes with other disorders. The association of pyostomatitis vegetans with inflammatory bowel disease, particularly ulcerative colitis, is well known and in most cases bowel disease precedes the onse...

journal_title：Clinical and experimental dermatology

authors： Hegarty AM,Barrett AW,Scully C

更新日期：2004-01-01 00:00:00

abstract：:Naevus comedonicus is a rare condition, thought to be a hamartoma in which cells of the pilosebaceous unit fail to develop appropriately. Although it is usually an isolated phenomenon, it has been associated with other defects, including those of the skeletal, ocular and central nervous system. A girl with this condit...

journal_title：Clinical and experimental dermatology

authors： Woods KA,Larcher VF,Harper JI

更新日期：1994-03-01 00:00:00

abstract：:Dystrophic epidermolysis bullosa (DEB) is caused by mutations in the COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils. The characteristic genetic lesion in dominant DEB (DDEB) is a glycine substitution in the collagenous domain of the protein. In this study, we identified a Chinese fami...

journal_title：Clinical and experimental dermatology

authors： Zhang XJ,Song YX,Zhang XQ,Yang S,Li M,Li CR,Yang CJ,Yang J

更新日期：2003-07-01 00:00:00

abstract：:Like many other cancers, melanoma has a significant genetic basis. However, its genetic pathways may involve multiple genes with probable interactions with sun exposure. Germline mutations in p16 or CDKN2A are found in a significant percentage of relatively rare melanoma families but p16 mutations are uncommon in spor...

journal_title：Clinical and experimental dermatology

authors： Bataille V

更新日期：2000-09-01 00:00:00

abstract：:In 1990 we reported the trends in presentation of malignant melanoma (MM) from 1986 to 1988 in a defined population in South Wales. Ten years after this initial study we reassessed the incidence of invasive MM in this defined population over a similar 3 year period. Using the local skin cancer registry we identified 1...

journal_title：Clinical and experimental dermatology

authors： Holme SA,Malinovsky K,Roberts DL

更新日期：2001-09-01 00:00:00

abstract：:Incipient osteomalacia developed in a Pakistani patient living in the UK after strict sunlight avoidance forming part of the management of the photosensitivity disorder, chronic actinic dermatitis. The patient's skin type and diet, which included calcium-binding phytates in chappattis, had increased his risk of the co...

journal_title：Clinical and experimental dermatology

authors： Kapur N,Creamer D,Hawk J

更新日期：2000-07-01 00:00:00

abstract：:Naevoid hypertrichosis is an unusual congenital disorder consisting of a solitary circumscribed area of terminal hair growth which is not associated with any other systemic abnormalities. We describe a patient with multiple areas of circumscribed naevoid hypertrichosis on the trunk and limbs who also had lipodystrophy...

journal_title：Clinical and experimental dermatology

authors： Cox NH,McClure JP,Hardie RA

更新日期：1989-01-01 00:00:00

abstract：:Bullous pemphigoid (BP) is an autoimmune disease mediated by autoantibodies against hemidesmosome components. This study used PCR-sequence-specific primers to genotype polymorphisms in HLA-DR and DQ in 25 BP patients and 57 normal controls from northern China. We found lower frequencies of DRB1*08 (DR8) and DRB1*08/DQ...

journal_title：Clinical and experimental dermatology

authors： Gao XH,Winsey S,Li G,Barnardo M,Zhu XJ,Chen HD,Song F,Zhai N,Fuggle S,Wojnarowska F

更新日期：2002-06-01 00:00:00

abstract：:Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a condition that is seldom reported in the paediatric literature and rarely in the dermatological literature. It has other disparate and confusing names and as histology is rarely obtained, the condition may be under-reported. We describe this disorder in the...

journal_title：Clinical and experimental dermatology

authors： Flann S,Munn SE

更新日期：2009-06-01 00:00:00

abstract：:We report 20 patients who contracted cutaneous leishmaniasis in Central and South America, 18 of them in Belize. The diagnosis was confirmed by the polymerase chain reaction (PCR) in 79% of those tested; the corresponding figure for histology was 62%, touch smear 46%, and culture 11%. Results of PCR can be falsely pos...

journal_title：Clinical and experimental dermatology

authors： Palmer RA,Tran D,Hepburn NC,Ashton RE

更新日期：2001-01-01 00:00:00

abstract：:Despite scarring being a recognized sequel of acne, the actual extent and incidence of residual scarring remains unknown. One hundred and eighty-five acne patients were included in this study (101 females, 84 males). Patients were selected from acne clinics and their acne scarring was examined. The scarring was quanti...

journal_title：Clinical and experimental dermatology

authors： Layton AM,Henderson CA,Cunliffe WJ

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:We have previously reported that about 30% of patients affected by a new variant of endemic pemphigus foliaceus (EPF) in El Bagre, Colombia (termed El Bagre-EPF or pemphigus Abreu-Manu) have systemic compromise. In the current study, we focused on studying autoreactivity to the kidney and its pathological co...

journal_title：Clinical and experimental dermatology

authors： Abreu-Velez AM,Howard MS,Yi H,Florez-Vargas AA

更新日期：2018-08-01 00:00:00

abstract：:We report a case of a 56-year-old woman who presented with a severe exacerbation of psoriasis with concurrent hypoglycaemic episodes. Methotrexate 17.5 mg weekly was required to control her psoriasis. Investigation of her hypoglycaemia showed raised levels of insulin, C-peptide and proinsulin. Radiological investigati...

journal_title：Clinical and experimental dermatology

authors： Field S,Kelly G,Tobin AM,Barragry JM,Conlon KC,Kirby B

更新日期：2008-03-01 00:00:00

abstract：:Contact allergy to various essential oils used in aromatherapy was demonstrated on patch testing in a 53-year-old patient suffering from relapsing eczema resistant to therapy on various uncovered parts of the skin, in particular the scalp, neck and hands. Sensitization was due to previous exposure to lavender, jasmine...

journal_title：Clinical and experimental dermatology

authors： Schaller M,Korting HC

更新日期：1995-03-01 00:00:00

abstract：:Evidence has suggested that vascular endothelial growth factor (VEGF), a crucial growth factor in regulating endothelial progenitor cells (EPCs), plays a central role in keloid formation. However, the levels of circulating EPCs in patients with keloid have not yet been explored. The aim of this study was to determine ...

journal_title：Clinical and experimental dermatology

authors： Zhang GY,Wu LC,Liao T,Chen G,Chen YH,Meng XC,Wang AY,Chen SY,Lin K,Lin DM,Gao WY,Li QF

更新日期：2016-03-01 00:00:00

abstract：:Rubinstein-Taybi syndrome (RSTS) is a rare congenital disorder, mainly characterized by postnatal growth retardation, intellectual disability, and facial and limb abnormalities. Although not considered as characteristic manifestations, numerous cutaneous anomalies have also been reported in patients with RSTS while th...

journal_title：Clinical and experimental dermatology

authors： Wang L,Deng Y,Zhou XL,Ma JJ,Li W

更新日期：2019-07-01 00:00:00

abstract：:Piloleiomyoma is a benign tumour originating in the smooth muscles of the arrector pili muscle in the skin. The lesions are often sensitive to touch, cold and emotional disturbance. We present a patient with multiple piloleiomyoma (MPL) of the submentum who underwent reconstructive surgery using a submental perforator...

journal_title：Clinical and experimental dermatology

authors： Matsushita S,Ishihara T,Takeda K,Uchida Y,Tamai M,Usuki K,Kanekura T

更新日期：2009-12-01 00:00:00

abstract：:Loceryl nail lacquer was developed to provide the effective antifungal drug, amorolfine, in a once-weekly dosage regimen combined with a convenient mode of application. Traditional formulations such as creams and nail solutions do not fulfil these requirements because they are wiped or washed off very rapidly. Amorolf...

journal_title：Clinical and experimental dermatology

authors： Pittrof F,Gerhards J,Erni W,Klecak G

更新日期：1992-09-01 00:00:00

abstract：:We present the case of a 68-year-old woman who developed a painful subcutaneous tumour in the sacral region. Histological examinations revealed a characteristic zonal pattern with a central zone of liquefactive necrosis, surrounded by proliferated atypical fibroblasts and prominent vessels, indicating ischaemic fascii...

journal_title：Clinical and experimental dermatology

authors： Kaneko T,Rokunohe D,Takiyoshi N,Minakawa S,Nakano H,Sawamura D

更新日期：2016-07-01 00:00:00

abstract：:We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one pat...

journal_title：Clinical and experimental dermatology

authors： Jacyk K,Smith A

更新日期：1990-09-01 00:00:00

abstract：:Dermatofibromata are common benign dermal tumours of unknown aetiology. They usually present as a single lesion on the limbs of young adults. Multiple dermatofibromata have been reported occurring in patients with autoimmune disease, who were receiving immunosuppressive treatment. A 25-year-old female is reported who ...

journal_title：Clinical and experimental dermatology

authors： Stainforth J,Goodfield MJ

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:We conducted a re-audit of the surgical practice of UK dermatologists for the treatment of nonmelanoma skin cancer and examined changes with reference to our previous audit in 2014. The audit was supplemented by a detailed assessment of completeness of the histopathology reports for each tumour. METHODS:UK ...

journal_title：Clinical and experimental dermatology

authors： Keith DJ,Bray AP,Brain A,Mohd Mustapa MF,Barrett HE,Lane S,Emmerich M,Jakes A,Barrett PD,de Berker DAR

更新日期：2020-01-01 00:00:00