Efficacy of topical corticosteroids in nickel-induced contact allergy.

abstract：BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

journal_title：Clinical and experimental dermatology

authors： Yue X,Wang A,Sun Y,Li Q

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The main cause of lichen simplex chronicus (LSC) is not known but there is evidence to suggest that neurological abnormalities may be implicated in its aetiology. AIM:To investigate neuropathy in patients with LSC on the limbs. METHODS:In total, 23 consecutive patients [15 women (65.2%) and 8 men (34.8%); ...

journal_title：Clinical and experimental dermatology

authors： Solak O,Kulac M,Yaman M,Karaca S,Toktas H,Kirpiko O,Kavuncu V

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). AIM:To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. METHODS:In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched ...

journal_title：Clinical and experimental dermatology

authors： Ucuz I,Altunisik N,Sener S,Turkmen D,Kavuran NA,Marsak M,Colak C

更新日期：2020-02-16 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：:Tetracyclines, including doxycycline, are widely used drugs that form an integral part of daily prescribing, and serious adverse reactions (SARs) are rarely reported. The frequency of hypoglycaemia complicating tetracycline treatment remains unknown, and is not a recognized complication. We describe an 80-year-old man...

journal_title：Clinical and experimental dermatology

authors： Tan CH,Shelley C,Harman KE

更新日期：2016-01-01 00:00:00

abstract：:It is well known that systemic corticosteroids arrest the progress of vitiligo and lead to repigmentation, but they may produce unacceptable side-effects. The use of high-dose prednisolone therapy to minimize the side-effects of systemic steroids has been reported, but there have been no reports on the effectiveness o...

journal_title：Clinical and experimental dermatology

authors： Lee Y,Seo YJ,Lee JH,Park JK

更新日期：2007-09-01 00:00:00

abstract：:Although many antihistamines are now in clinical use, few studies directly compare their pharmacodynamic and sedative activities in humans in vivo. We designed a double-blind, placebo-controlled, crossover study to compare the inhibitory effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-in...

journal_title：Clinical and experimental dermatology

authors： Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Recessive dystrophic epidermolysis bullosa (RDEB) is an autosomal recessive skin disease caused by mutations in the type VII collagen gene (COL7A1), resulting in detachment of the entire epidermis due to loss or hypoplasticity of the anchoring fibrils that normally secure the basement membrane to the underly...

journal_title：Clinical and experimental dermatology

authors： Hanafusa T,Tamai K,Umegaki N,Yamaguchi Y,Fukuda S,Nishikawa Y,Yaegashi N,Okuyama R,McGrath JA,Katayama I

更新日期：2012-01-01 00:00:00

abstract：:The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

journal_title：Clinical and experimental dermatology

authors： Norris P,Bacon K,Bird C,Hawk J,Camp R

更新日期：1999-07-01 00:00:00

abstract：:A large variety of cutaneous reactions to malignancy have been described but to our knowledge none include psoriasis. Two cases of psoriasiform reactions in association with malignancy were first documented by Braverman, and Bazex's syndrome is now well documented in the literature. Both conditions, although clinicall...

journal_title：Clinical and experimental dermatology

authors： Hughes BR,Cotterill JA

更新日期：1993-01-01 00:00:00

abstract：:Stewart-Bluefarb syndrome (SBS) is a subtype of pseudo-Kaposi sarcoma (PKS), which is associated with congenital arteriovenous malformation. It is a rare syndrome, characterized by cutaneous lesions with onset in the second decade of life. We report a case of SBS in a 33-year-old man presenting with a 15-year history ...

journal_title：Clinical and experimental dermatology

authors： Verma SB,Vasani R

更新日期：2016-07-01 00:00:00

abstract：:A 71-year-old woman with vitiligo developed multiple actinic keratoses only on the vitiligo skin of sun-exposed areas. She had worked outdoors as a farmer for a long period. Although actinic skin cancers arising on vitiligo skin have rarely been reported, the present case demonstrates that vitiligo skin is more suscep...

journal_title：Clinical and experimental dermatology

authors： Yashiro K,Nakagawa T,Takaiwa T,Inai M

更新日期：1999-05-01 00:00:00

abstract：:There is variation in the treatment of lower limb cellulitis (LLC) with no agreement on the most effective antibiotic regimen. Many patients with cellulitis fail to respond to first-line antibiotics. This can negatively affect patient care and result in unnecessary hospital admissions. The aim of this systematic revie...

journal_title：Clinical and experimental dermatology

authors： Mistry K,Sharma S,Patel M,Grindlay D,Janjuha R,Smart P,Levell NJ

更新日期：2021-01-01 00:00:00

abstract：:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica of...

journal_title：Clinical and experimental dermatology

authors： Owen CM,Murphy H,Yates VM

更新日期：2001-03-01 00:00:00

abstract：:Capecitabine was developed as a prodrug of 5-fluorouracil (FU), with the goal of improving tolerability and intratumour drug concentrations through tumour-specific conversion to the active drug against numerous types of neoplasms. The most frequent adverse cutaneous reaction associated with capecitabine is hand foot s...

journal_title：Clinical and experimental dermatology

authors： Do JE,Kim YC

更新日期：2007-09-01 00:00:00

abstract：:This article forms part of a series of annual updates that summarizes the evidence base for atopic eczema (AE). It provides a summary of key findings from 28 systematic reviews that were published or indexed during 2017, and focuses on the epidemiology, aetiology and risk factors of AE. AE is the largest single contri...

journal_title：Clinical and experimental dermatology

authors： Hale G,Davies E,Grindlay DJC,Rogers NK,Harman KE

更新日期：2019-12-01 00:00:00

abstract：:The precursor protein proopiomelanocortin (POMC) produces many biologically active peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and beta-endorphin. The gene for alpha-MSH is encoded for by the POMC gene, but alpha-MSH c...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-05-01 00:00:00

abstract：:Cutaneous amyloidosis and multiple endocrine neoplasia 2A (MEN 2A) have been previously reported in several families. A genetic linkage of both disorders has recently been described. Notalgia paraesthetica has been suggested to be involved in the aetiology of amyloidosis in such patients. We report such an association...

journal_title：Clinical and experimental dermatology

authors： de Argila D,Ortiz-Romero PL,Ortiz-Frutos J,Rodriguez-Peralto JL,Iglesias L

更新日期：1996-07-01 00:00:00

abstract：:A 65-year-old female suffered trauma to her left hand on which acrodermatitis continua (psoriasis of Hallopeau) developed. It is suggested that the persistent pain of this skin condition, its poor response to treatment and her allied mental state led to the development of a severe algodystrophy with marked underlying ...

journal_title：Clinical and experimental dermatology

authors： Stephens CJ,McGibbon DH

更新日期：1989-11-01 00:00:00

abstract：:Idiopathic solar urticaria (SU) is a rare, debilitating photodermatosis, which may be difficult to treat. First-line treatment with antihistamines is effective in mild cases, but remission after phototherapeutic induction of tolerance is often short-lived. Other treatment options include plasma exchange, photopheresis...

journal_title：Clinical and experimental dermatology

authors： Hughes R,Cusack C,Murphy GM,Kirby B

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that concomitant administration of food may enhance the bioavailability of oral retinoids. AIM:To assess the influence of food on the pharmacokinetics (PK) of alitretinoin after a single oral dose. METHODS:This was a single-dose, open-label, randomized, crossover study, which en...

journal_title：Clinical and experimental dermatology

authors： Schmitt-Hoffmann AH,Roos B,Sauer J,Schleimer M,Kovācs P,Stoeckel K,Maares J

更新日期：2011-04-01 00:00:00

abstract：:A lighter or whiter complexion is socially desirable in many cultures. This has led to an unregulated and highly profitable market in skin-lightening creams that are readily available over the counter or on the internet. Plant extracts and newer tyrosinase inhibitors such as kojic acid or its derivative kojic dipalmit...

journal_title：Clinical and experimental dermatology

authors： Madhogaria S,Ahmed I

更新日期：2010-06-01 00:00:00

abstract：:Vitiligo usually begins in childhood with approximately half of the patients manifesting onset of disease prior to the age of 20 years. Treatment options in this age group are few and have disappointing response rates. This study was designed to evaluate the role of narrow-band UVB in the treatment of generalized viti...

journal_title：Clinical and experimental dermatology

authors： Kanwar AJ,Dogra S

更新日期：2005-07-01 00:00:00

abstract：:Three cases of chondrodermatitis nodularis helicis (CDNH) in patients with the limited form of systemic sclerosis are described. Two of the three cases were noted during regular follow-up visits and the third case was found as part of a survey of the 21 other patients with systemic sclerosis routinely seen in the depa...

journal_title：Clinical and experimental dermatology

authors： Bottomley WW,Goodfield MD

更新日期：1994-05-01 00:00:00

abstract：:We report a case of the rare porokeratosis variant porokeratosis ptychotropica (PP). A circumferential perianal plaque and the characteristic histology of multiple cornoid lamellae with underlying dermal amyloid deposition were seen. Amyloid deposition was seen in the biopsied intertriginous area of the plaque only, w...

journal_title：Clinical and experimental dermatology

authors： Tallon B,Blumental G,Bhawan J

更新日期：2009-12-01 00:00:00

abstract：:Ichthyosis hystrix, Curth-Macklin type (IHCM) is an extremely rare autosomal dominant dermatosis caused by mutations in the keratin genes, KRT1 or KRT10, which often manifests as extensive, dark, spiky or verrucous plaques and severe palmoplantar keratoderma. We report a novel frameshift truncation mutation, c.1596_15...

journal_title：Clinical and experimental dermatology

authors： Yang Z,Xu Z,Zhang N,Ma L

更新日期：2020-08-01 00:00:00

abstract：:We report the case of a 46-year-old Indian woman who developed a hyperimmune response to a typhoid booster injection in association with the development of pemphigus vulgaris. To our knowledge, this association has not previously been reported. ...

journal_title：Clinical and experimental dermatology

authors： Bellaney GJ,Rycroft RJ

更新日期：1996-11-01 00:00:00

abstract：:We describe two patients with newly diagnosed dermatoses localizing to the radiotherapy field following treatment for breast cancer. Patient 1 was a 53-year-old woman who developed bullous morphoea on her left breast two years after radiotherapy. Patient 2 was a 43-year-old woman who developed urticaria pigmentosa on ...

journal_title：Clinical and experimental dermatology

authors： Hellen R,Kiely C,Murad A,Mulligan N,Coffey J,Lenane P,Moloney FJ

更新日期：2014-12-01 00:00:00

abstract：:Clinicians have become increasingly aware of the important effects of psoriasis on patients' quality of life. As a result, several measures of the disabilities and handicaps associated with psoriasis have been developed. The Psoriasis Disability Index (PDI) has been shown to be sensitive to changes in the extent of le...

journal_title：Clinical and experimental dermatology

authors： Kent G,al-Abadie M

更新日期：1993-09-01 00:00:00