Lichen simplex chronicus as a symptom of neuropathy.

abstract：:Guadeloupe is a French Caribbean island, with a population of mainly African ancestry, and a high standard of living. We recorded the dermatological diagnoses in 5000 new patients attending dermatologists. The main diagnoses were acne (16.4%), superficial mycoses (12.8%), and eczema (10.5%). Diseases considered to be ...

journal_title：Clinical and experimental dermatology

authors： Mahé A,Mancel E

更新日期：1999-09-01 00:00:00

abstract：:We report a case of cutaneous alternariosis in an immunocompetent 85-year-old man. Identification of the causative organism in this patient was achieved by 18S rRNA sequencing. A 6-month course of itraconazole led to a good clinical response. ...

journal_title：Clinical and experimental dermatology

authors： Williams C,Layton AM,Kerr K,Kibbler C,Barton RC

更新日期：2008-07-01 00:00:00

abstract：:We performed an immunohistochemical study with 11 antikeratin antibodies using the newly developed AMeX (acetone-methylbenzoate-xylene) tissue processing method. Specimens processed with this method showed almost as good preservation and morphological detail as routinely processed, formalin-fixed and paraffin-embedded...

journal_title：Clinical and experimental dermatology

authors： Ansai SI,Koseki S,Hozumi Y,Kondo S

更新日期：1994-11-01 00:00:00

abstract：:We report a case of a 56-year-old woman who presented with a severe exacerbation of psoriasis with concurrent hypoglycaemic episodes. Methotrexate 17.5 mg weekly was required to control her psoriasis. Investigation of her hypoglycaemia showed raised levels of insulin, C-peptide and proinsulin. Radiological investigati...

journal_title：Clinical and experimental dermatology

authors： Field S,Kelly G,Tobin AM,Barragry JM,Conlon KC,Kirby B

更新日期：2008-03-01 00:00:00

abstract：:Steatocystoma multiplex is a rare, autosomal dominant condition characterized by multiple cysts, usually arising on the trunk and proximal extremities at puberty. We present two unrelated women with sporadic steatocystoma multiplex strictly confined to the vulva and arising at an older age. These cases represent an un...

journal_title：Clinical and experimental dermatology

authors： Rongioletti F,Cattarini G,Romanelli P

更新日期：2002-09-01 00:00:00

abstract：:Human papillomavirus (HPV) is the most common sexually transmitted disorder in young, sexually active populations in the USA and Europe. Giant condyloma acuminatum (GCA) is a unique variant of condyloma acuminata, characterized by local aggressive behaviour despite benign histology. It carries a substantial risk of sq...

journal_title：Clinical and experimental dermatology

authors： Erkek E,Basar H,Bozdogan O,Emeksiz MC

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Androgenic alopecia is known to be androgen-dependent. Insulin is found in hair follicles and may play a role in the regulation of androgen metabolism and the hair-growth cycle. OBJECTIVES:To compare the insulin resistance between people with androgenic alopecia and a control group. METHODS:A case-control ...

journal_title：Clinical and experimental dermatology

authors： Nabaie L,Kavand S,Robati RM,Sarrafi-Rad N,Kavand S,Shahgholi L,Meshkat-Razavi G

更新日期：2009-08-01 00:00:00

abstract：:Secukinumab is an interleukin (IL)-17 monoclonal antibody inhibiting T-helper (Th)1-mediated immune response. It has proven high efficacy for moderate to severe psoriasis but data on its long-term toxicities are limited. We describe two patients who received secukinumab for clinically presumed psoriasis, but were subs...

journal_title：Clinical and experimental dermatology

authors： Yoo J,Shah F,Velangi S,Stewart G,Scarisbrick JS

更新日期：2019-06-01 00:00:00

abstract：:Complete deficiency of the fourth component of complement (C4) is an extremely rare condition. However, it has been reported that partial C4 deficiency can occur in normal subjects, and is associated with several immune diseases. We report a 44-year-old woman who developed slight oedema and punctate purpura on her low...

journal_title：Clinical and experimental dermatology

authors： Kosaka S,Osada S,Kaneko T,Nishimura S,Kawana S

更新日期：2013-07-01 00:00:00

abstract：:We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one pat...

journal_title：Clinical and experimental dermatology

authors： Jacyk K,Smith A

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:In drug-induced toxic epidermal necrolysis (TEN), the epidermal destruction is associated with a slight to moderate lymphomonocytic cell infiltrate. Interleukin (IL)-8, which is a keratinocyte-derived pro-inflammatory cytokine, might be involved in this process. The IL-8 receptor CXCR2 has also been shown to...

journal_title：Clinical and experimental dermatology

authors： Paquet P,Ribbens C,Piérard GE

更新日期：2007-11-01 00:00:00

abstract：:Palmoplantar punctate keratoses may be the main cutaneous sign of various diseases (porokeratosis punctata palmaris et plantaris, keratosis punctata of the palmar creases, familial punctate palmoplantar keratoderma) or represent a secondary feature [Cowden's syndrome (CS) and Darier's disease]. In CS, such keratoses u...

journal_title：Clinical and experimental dermatology

authors： Ferran M,Bussaglia E,Matias-Guiu X,Pujol RM

更新日期：2009-07-01 00:00:00

abstract：:Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per da...

journal_title：Clinical and experimental dermatology

authors： Tan A,Tan HH,Lee CC,Ng SK

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Atopic eczema (AE) is characterized by reduced skin hydration (SH) and impaired integrity of the skin. Proper emollient usage is an important facet of AE management and patients are encouraged to use emollients liberally. AIM:To evaluate whether the amount of emollient and skin cleanser used correlates with...

journal_title：Clinical and experimental dermatology

authors： Hon KL,Ching GK,Leung TF,Choi CY,Lee KK,Ng PC

更新日期：2010-01-01 00:00:00

abstract：:Ninety-six patients with a clinical and parasitological diagnosis of cutaneous leishmaniasis were recruited to a comparative randomized clinical trial evaluating the efficacy of topical paromomycin vs. weekly intralesional injections of meglumine antimoniate. The patients were randomly divided into two treatment group...

journal_title：Clinical and experimental dermatology

authors： Faghihi G,Tavakoli-kia R

更新日期：2003-01-01 00:00:00

abstract：:Ichthyosis hystrix, Curth-Macklin type (IHCM) is an extremely rare autosomal dominant dermatosis caused by mutations in the keratin genes, KRT1 or KRT10, which often manifests as extensive, dark, spiky or verrucous plaques and severe palmoplantar keratoderma. We report a novel frameshift truncation mutation, c.1596_15...

journal_title：Clinical and experimental dermatology

authors： Yang Z,Xu Z,Zhang N,Ma L

更新日期：2020-08-01 00:00:00

abstract：:Many types of histiocytoses have been described. We present a case of a 56-year-old woman who presented with multiple nodules on the hands. On histological examination of an excision biopsy, a mainly dermal lesion was seen, with scattered mononuclear inflammatory cells and occasional multinucleated cells in the backgr...

journal_title：Clinical and experimental dermatology

authors： Patel AN,Cohen SN,Leach IH,Scharrer K

更新日期：2012-04-01 00:00:00

abstract：:Twenty-six men who presented with male pattern baldness (androgen-dependent alopecia), were quantitatively evaluated for scalp hair variables and compared with 13 age-matched controls. Compared to controls, significant mean differences for hair variables were found in the frontal-vertex area, while in the occipital ar...

journal_title：Clinical and experimental dermatology

authors： Rushton DH,Ramsay ID,Norris MJ,Gilkes JJ

更新日期：1991-05-01 00:00:00

abstract：:There is variation in the treatment of lower limb cellulitis (LLC) with no agreement on the most effective antibiotic regimen. Many patients with cellulitis fail to respond to first-line antibiotics. This can negatively affect patient care and result in unnecessary hospital admissions. The aim of this systematic revie...

journal_title：Clinical and experimental dermatology

authors： Mistry K,Sharma S,Patel M,Grindlay D,Janjuha R,Smart P,Levell NJ

更新日期：2021-01-01 00:00:00

abstract：:Determining the risk of progression to systemic lupus erythematosus (SLE) among patients diagnosed with discoid lupus erythematosus (DLE), and the time frame of this risk, are important clinical questions. Past reports have demonstrated a wide time frame of progression from DLE to SLE, with mean time to progression of...

journal_title：Clinical and experimental dermatology

authors： Elman SA,Joyce C,Costenbader KH,Merola JF

更新日期：2020-01-01 00:00:00

abstract：:Dermanyssus gallinae is a mite that normally parasitizes small birds but may occasionally bite humans. We report an unusual case of an 82-year-old woman who presented with pruritus and bite-like lesions over her trunk. Other members of the household were also affected. On physical examination, mites < 1 mm in size wer...

journal_title：Clinical and experimental dermatology

authors： Collgros H,Iglesias-Sancho M,Aldunce MJ,Expósito-Serrano V,Fischer C,Lamas N,Umbert-Millet P

更新日期：2013-06-01 00:00:00

abstract：:This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

journal_title：Clinical and experimental dermatology

authors： Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

更新日期：1996-01-01 00:00:00

abstract：:Naevus comedonicus is a rare condition, thought to be a hamartoma in which cells of the pilosebaceous unit fail to develop appropriately. Although it is usually an isolated phenomenon, it has been associated with other defects, including those of the skeletal, ocular and central nervous system. A girl with this condit...

journal_title：Clinical and experimental dermatology

authors： Woods KA,Larcher VF,Harper JI

更新日期：1994-03-01 00:00:00

abstract：:Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is an uncommon premalignant condition involving the glans penis. We report the case of an 86-year-old man who presented with phimosis and pain on retracting his foreskin. He had previously undergone circumcision, which revealed a hyperkeratotic plaque with...

journal_title：Clinical and experimental dermatology

authors： Choo KJL,Ng SK,Sim CS,Cheng SWN

更新日期：2017-06-01 00:00:00

abstract：:Drug reactions are common in HIV-1 disease, with the incidence having been reported to increase with increasing stage and with CD4+ T-cell counts below 200/microliters. However, there have been numerous reports of patients in which rechallenge, dosing changes or continued therapy have resulted in no recurrence or else...

journal_title：Clinical and experimental dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,Ng TH,Wagner KF

更新日期：1997-05-01 00:00:00

abstract：:Controlled trials and clinical experience indicate that systemic cyclosporin A and tacrolimus are effective treatments for psoriasis, and that cyclosporin A also improves atopic eczema. A variety of other inflammatory and non-inflammatory skin diseases are probably also responsive to these drugs. However, the widespre...

journal_title：Clinical and experimental dermatology

authors： Reynolds NJ,Al-Daraji WI

更新日期：2002-10-01 00:00:00

abstract：:The high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, plays a central role in the initiation and control of atopic allergic inflammation. On mast cells and basophils, the function of the receptor is well known and constitutes cellular degranulation and the release of various mediators. FcepsilonRI on ant...

journal_title：Clinical and experimental dermatology

authors： von Bubnoff D,Novak N,Kraft S,Bieber T

更新日期：2003-03-01 00:00:00

abstract：:A 65-year-old female suffered trauma to her left hand on which acrodermatitis continua (psoriasis of Hallopeau) developed. It is suggested that the persistent pain of this skin condition, its poor response to treatment and her allied mental state led to the development of a severe algodystrophy with marked underlying ...

journal_title：Clinical and experimental dermatology

authors： Stephens CJ,McGibbon DH

更新日期：1989-11-01 00:00:00

abstract：:Contact allergy to various essential oils used in aromatherapy was demonstrated on patch testing in a 53-year-old patient suffering from relapsing eczema resistant to therapy on various uncovered parts of the skin, in particular the scalp, neck and hands. Sensitization was due to previous exposure to lavender, jasmine...

journal_title：Clinical and experimental dermatology

authors： Schaller M,Korting HC

更新日期：1995-03-01 00:00:00

abstract：:We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

journal_title：Clinical and experimental dermatology

authors： Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

更新日期：2000-01-01 00:00:00