Treatment of toxic epidermal necrolysis in AIDS with intravenous immunoglobulins.

abstract：:Contact hypersensitivity from topical corticosteroids is becoming increasingly recognized; it is present in 2-5% of the patients attending contact dermatitis clinics. The use of a corticosteroid series containing tixocortal pivalate 1% (petrolatum), to detect hypersensitivity to hydrocortisone, and other steroids 1% (...

journal_title：Clinical and experimental dermatology

authors： Wilkinson SM

更新日期：1994-01-01 00:00:00

abstract：:Humans are the natural host for eight of more than 80 known herpes viruses. Infections with herpes simplex virus type 1 (HSV-1) are ubiquitous worldwide and highly transmissible. Herpes simplex labialis (HSL) is the best-recognized recrudescent infection of the lips and perioral tissues caused by HSV-1. Facial lesions...

journal_title：Clinical and experimental dermatology

authors： Fatahzadeh M,Schwartz RA

更新日期：2007-11-01 00:00:00

abstract：:A 23-year-old woman presented with a 10 year history of excessive sweating (hyperhidrosis), mostly in the axillae, and to a lesser extent the groin and hands. Initial treatment with a sedative antihistamine and topical Driclor (aluminium chloride hexahydrate in 2% alcohol) for 14 weeks resulted in no improvement. Axil...

journal_title：Clinical and experimental dermatology

authors： Payne CM,Doe PT

更新日期：1998-01-01 00:00:00

abstract：:Tetracyclines, including doxycycline, are widely used drugs that form an integral part of daily prescribing, and serious adverse reactions (SARs) are rarely reported. The frequency of hypoglycaemia complicating tetracycline treatment remains unknown, and is not a recognized complication. We describe an 80-year-old man...

journal_title：Clinical and experimental dermatology

authors： Tan CH,Shelley C,Harman KE

更新日期：2016-01-01 00:00:00

abstract：:Tumoral calcinosis is an uncommon ectopic calcification syndrome characterized clinically by the presence of irregular, painless, periarticular soft tissue calcifying masses, and pathologically by fibrous-walled cystic spaces containing structureless calcific debris and associated with a variable inflammatory reaction...

journal_title：Clinical and experimental dermatology

authors： Harwood CA,Cook MG,Mortimer PS

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:In patients with psoriasis, videocapillaroscopy has been used to visualize the typical modifications in the microcirculatory architecture. AIM:To evaluate the modifications of the superficial capillary bed in a psoriatic plaque and healthy perilesional skin during treatment with a topical steroid. METHODS:...

journal_title：Clinical and experimental dermatology

authors： Stinco G,Lautieri S,Piccirillo F,Valent F,Patrone P

更新日期：2009-12-01 00:00:00

abstract：:Controlled trials and clinical experience indicate that systemic cyclosporin A and tacrolimus are effective treatments for psoriasis, and that cyclosporin A also improves atopic eczema. A variety of other inflammatory and non-inflammatory skin diseases are probably also responsive to these drugs. However, the widespre...

journal_title：Clinical and experimental dermatology

authors： Reynolds NJ,Al-Daraji WI

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

journal_title：Clinical and experimental dermatology

authors： Yue X,Wang A,Sun Y,Li Q

更新日期：2018-12-01 00:00:00

abstract：:Loceryl nail lacquer was developed to provide the effective antifungal drug, amorolfine, in a once-weekly dosage regimen combined with a convenient mode of application. Traditional formulations such as creams and nail solutions do not fulfil these requirements because they are wiped or washed off very rapidly. Amorolf...

journal_title：Clinical and experimental dermatology

authors： Pittrof F,Gerhards J,Erni W,Klecak G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:The motivations for patients presenting to melanoma screening clinics (MSCs) with concerning skin lesions are poorly understood. Social media (SoMe) refers to online platforms designed to facilitate sharing of information with billions of users worldwide. There is evidence of patients posting skin lesion 'se...

journal_title：Clinical and experimental dermatology

authors： Guckian J,Jobling K,Oliphant T,Weatherhead S,Blasdale K

更新日期：2020-04-01 00:00:00

abstract：:Acquired cold urticaria (ACU) is a frequent subtype of physical urticaria that is caused by the release of proinflammatory mast cell mediators after cold exposure. Although the underlying causes of ACU still remain to be clarified in detail, a wide range of diseases has been reported to be associated with ACU. This re...

journal_title：Clinical and experimental dermatology

authors： Siebenhaar F,Weller K,Mlynek A,Magerl M,Altrichter S,Vieira Dos Santos R,Maurer M,Zuberbier T

更新日期：2007-05-01 00:00:00

abstract：:Although surgery may be curative in early malignant melanoma, its effect on survival lessens with each succeeding stage of the disease. A wide variety of immunological strategies have therefore been used to improve the prognosis of patients with malignant melanoma, but adjuvant therapy with interferon (IFN)-alpha is t...

journal_title：Clinical and experimental dermatology

authors： Russell-Jones R

更新日期：2000-01-01 00:00:00

abstract：:We describe the results of a single-centre, double-blind, vehicle-controlled, parallel group study on the quantitative effects of 2% fusidic acid lotion (Fucidin lotion) in facial acne vulgaris. The trial was completed by 52 patients aged 15-25 years with mild to moderate acne who had been randomized to either Fucidin...

journal_title：Clinical and experimental dermatology

authors： Sommer S,Bojar R,Cunliffe WJ,Holland D,Holland KT,Naags H

更新日期：1997-09-01 00:00:00

abstract：:Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is an uncommon premalignant condition involving the glans penis. We report the case of an 86-year-old man who presented with phimosis and pain on retracting his foreskin. He had previously undergone circumcision, which revealed a hyperkeratotic plaque with...

journal_title：Clinical and experimental dermatology

authors： Choo KJL,Ng SK,Sim CS,Cheng SWN

更新日期：2017-06-01 00:00:00

abstract：:Vitiligo usually begins in childhood with approximately half of the patients manifesting onset of disease prior to the age of 20 years. Treatment options in this age group are few and have disappointing response rates. This study was designed to evaluate the role of narrow-band UVB in the treatment of generalized viti...

journal_title：Clinical and experimental dermatology

authors： Kanwar AJ,Dogra S

更新日期：2005-07-01 00:00:00

abstract：:Endogenous ochronosis or alkaptonuria is a rare, autosomal recessive disease of tyrosine metabolism that is caused by a deficiency of the enzyme homogentisic acid oxidase. The disease results in the accumulation and deposition of homogentisic acid in the cartilage, eyelids, forehead, cheeks, axillae, genital region, b...

journal_title：Clinical and experimental dermatology

authors： Turgay E,Canat D,Gurel MS,Yuksel T,Baran MF,Demirkesen C

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:We conducted a re-audit of the surgical practice of UK dermatologists for the treatment of nonmelanoma skin cancer and examined changes with reference to our previous audit in 2014. The audit was supplemented by a detailed assessment of completeness of the histopathology reports for each tumour. METHODS:UK ...

journal_title：Clinical and experimental dermatology

authors： Keith DJ,Bray AP,Brain A,Mohd Mustapa MF,Barrett HE,Lane S,Emmerich M,Jakes A,Barrett PD,de Berker DAR

更新日期：2020-01-01 00:00:00

abstract：:We present two patients who developed pseudoporphyria whilst taking isotretinoin (Roaccutane). At that time, both patients were receiving other agents which could be incriminated as causing their pseudoporphyria. However, it is significant that these other agents had been longstanding and that the porphyria-like cutan...

journal_title：Clinical and experimental dermatology

authors： Riordan CA,Anstey A,Wojnarowska F

更新日期：1993-01-01 00:00:00

abstract：:Rapp-Hodgkin syndrome (RHS) is an autosomal dominant disorder characterized by ectodermal dysplasia and cleft lip/cleft palate. Very recently, mutations in p63 have been identified as a cause of RHS; to date five such mutations have been identified. We describe a Thai girl with RHS. She had short stature, ectodermal d...

journal_title：Clinical and experimental dermatology

authors： Shotelersuk V,Janklat S,Siriwan P,Tongkobpetch S

更新日期：2005-05-01 00:00:00

abstract：:A 68-year-old Caucasian male presented with a 5-week history of a widespread pruritic papular eruption. Histology from a papule on the left shoulder showed a dense dermal infiltrate of large mononuclear cells which were positive for leucocyte common antigen, KP1 and PGM1, with an MIB-1 proliferating fraction of 40%, d...

journal_title：Clinical and experimental dermatology

authors： Millard TP,Aitchison R,Wilkinson JD

更新日期：2003-03-01 00:00:00

abstract：:Identification of mutations in the hairless (HR) gene in patients with atrichia with papular lesions (APL) has proven of critical importance, as it provides a basis for the differentiation between APL and alopecia universalis. The establishment of the diagnostic criteria for APL has triggered the identification of a l...

journal_title：Clinical and experimental dermatology

authors： Massé M,Martinez-Mir A,Lam H,Geraghty MT,Christiano AM

更新日期：2005-07-01 00:00:00

abstract：:The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...

journal_title：Clinical and experimental dermatology

authors： Jones SK,Handfield-Jones S,Kennedy CT

更新日期：1990-05-01 00:00:00

abstract：:Imprinting is the process whereby genetic alleles responsible for a phenotype are derived from one parent only. It is an epigenetic phenomenon resulting from DNA methylation or modification of protruding histones. When imprinted genes are disrupted, syndromes with characteristic patterns of inheritance and multisystem...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-09-01 00:00:00

abstract：:We wish to report the progress of a patient with pyoderma faciale and Crohn's disease. The patient is interesting in that on two occasions the relapse in her skin condition coincided with the introduction of non-steroidal anti-inflammatory drugs. Therapy with isotretinoin was effective and well tolerated. ...

journal_title：Clinical and experimental dermatology

authors： McHenry PM,Hudson M,Smart LM,Rennie JA,Mowat NA,White MI

更新日期：1992-11-01 00:00:00

abstract：:Like many other cancers, melanoma has a significant genetic basis. However, its genetic pathways may involve multiple genes with probable interactions with sun exposure. Germline mutations in p16 or CDKN2A are found in a significant percentage of relatively rare melanoma families but p16 mutations are uncommon in spor...

journal_title：Clinical and experimental dermatology

authors： Bataille V

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Epidermal replacement is an important step in the management of patients with post-traumatic and iatrogenic scars. Skin-colour variation from disease or trauma causes significant changes in self-image and appearance. AIM:The aim of our study was to analyse the results obtained with a novel autologous cell-h...

journal_title：Clinical and experimental dermatology

authors： Cervelli V,De Angelis B,Spallone D,Lucarini L,Arpino A,Balzani A

更新日期：2010-10-01 00:00:00

abstract：:Sarcoidosis is a rare disease among children, manifesting differently in children below and above 4-5 years of age. Although the exact incidence and prevalence of childhood sarcoidosis is not known, the cutaneous involvement is frequent in both children and adults. Infiltration of old cutaneous scars with sarcoid gran...

journal_title：Clinical and experimental dermatology

authors： Singal A,Thami GP,Goraya JS

更新日期：2005-05-01 00:00:00

abstract：:The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne th...

journal_title：Clinical and experimental dermatology

authors： Martin AR,Lookingbill DP,Botek A,Light J,Thiboutot D,Girman CJ

更新日期：2001-07-01 00:00:00

abstract：:The primary cause of collagen degeneration in necrobiosis lipoidica (NL) is proposed to be immunologically mediated vascular disease. Ultraviolet (UV)A1 has been used successfully to treat scleroderma in which both vascular damage and collagen dysregulation also occur. We treated six patients with NL [(five women; mea...

journal_title：Clinical and experimental dermatology

authors： Beattie PE,Dawe RS,Ibbotson SH,Ferguson J

更新日期：2006-03-01 00:00:00

abstract：:The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site (face, dorsal right forearm and han...

journal_title：Clinical and experimental dermatology

authors： Green C,Orchard G,Cerio R,Hawk JL

更新日期：1998-07-01 00:00:00