Endogenous ochronosis.

abstract：:This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It provides a summary of key findings from 15 systematic reviews that were published during 2015, and focuses on the epidemiology and methodology issues ...

journal_title：Clinical and experimental dermatology

authors： Davies E,Rogers NK,Lloyd-Lavery A,Grindlay DJC,Thomas KS

更新日期：2018-06-01 00:00:00

abstract：:A large variety of cutaneous reactions to malignancy have been described but to our knowledge none include psoriasis. Two cases of psoriasiform reactions in association with malignancy were first documented by Braverman, and Bazex's syndrome is now well documented in the literature. Both conditions, although clinicall...

journal_title：Clinical and experimental dermatology

authors： Hughes BR,Cotterill JA

更新日期：1993-01-01 00:00:00

abstract：:Chronic photodamage of the skin manifests itself as extrinsic skin ageing (photoageing) and photocarcinogenesis. DNA photodamage and UV-generated reactive oxygen species are the initial molecular events that lead to most of the typical histological and clinical manifestations of chronic photodamage of the skin. Knowle...

journal_title：Clinical and experimental dermatology

authors： Trautinger F

更新日期：2001-10-01 00:00:00

abstract：:Myiasis is a condition resulting from the invasion of tissues or organs of man or animals by the larvae of dipterous flies. The distribution of myiasis is worldwide, with more cases being reported from tropical, subtropical, and warm temperate areas. The various forms of myiasis may be classified from an entomological...

journal_title：Clinical and experimental dermatology

authors： Delir S,Handjani F,Emad M,Ardehali S

更新日期：1999-07-01 00:00:00

abstract：:A 48-year-old patient presented with a nonhealing leg ulcer and a raised white blood cell count. He was diagnosed with pyoderma gangrenosum (PG) and small lymphocytic leukaemia/chronic lymphocytic leukaemia (SLL/CLL). Eight months later, after undergoing treatment with chlorambucil for the SLL/CLL, and prednisone, cic...

journal_title：Clinical and experimental dermatology

authors： Branagan NM,Higgins SP,Halim SA,Le TH

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:In drug-induced toxic epidermal necrolysis (TEN), the epidermal destruction is associated with a slight to moderate lymphomonocytic cell infiltrate. Interleukin (IL)-8, which is a keratinocyte-derived pro-inflammatory cytokine, might be involved in this process. The IL-8 receptor CXCR2 has also been shown to...

journal_title：Clinical and experimental dermatology

authors： Paquet P,Ribbens C,Piérard GE

更新日期：2007-11-01 00:00:00

abstract：:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica of...

journal_title：Clinical and experimental dermatology

authors： Owen CM,Murphy H,Yates VM

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common form of skin carcinoma. AIM:To investigate the function of key micro(mi)RNAs and to explore the potential molecular mechanisms involved in BCC. METHODS:The microarray dataset GSE34535, which comprises seven BCC samples and seven control samples, was downloaded ...

journal_title：Clinical and experimental dermatology

authors： Mi X,Lai K,Yan L,Xie S,Qiu X,Xiao S,Wei S

更新日期：2020-12-01 00:00:00

abstract：:Alopecia areata (AA) is a recurrent, immune-mediated, hair-loss disorder. It is associated with other autoimmune disorders that carry a high risk of cardiovascular disease (CVD). However, there is a lack of reports on the association of cardiovascular comorbidities and AA. Cardiac troponin I is a biomarker of myocardi...

journal_title：Clinical and experimental dermatology

authors： El-Sayed Mahmoud Marie R,El-Sayed GAK,Attia FM,Gomaa AHA

更新日期：2021-01-01 00:00:00

abstract：:We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

journal_title：Clinical and experimental dermatology

authors： Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

更新日期：2000-01-01 00:00:00

abstract：:Ten psoriatic patients were treated with an accelerated PUVA regimen. Nine patients cleared in an average of 13.7 treatments (range 4-24) after an average total UVA dose of 83 J/cm2 (range 18-186). One patient had to withdraw due to pruritus and burning and six others had burning problems. The high incidence of burnin...

journal_title：Clinical and experimental dermatology

authors： Green C,George S,Lakshmipathi T,Ferguson J

更新日期：1993-07-01 00:00:00

abstract：:The use of cyclosporin A (CSA) for the treatment of severe psoriasis is well established. However its use is limited by its adverse effects, especially nephrotoxicity. We reviewed 28 patients treated with CSA for severe psoriasis over an 11-year period. All patients were on long-term CSA treatment (median duration 55....

journal_title：Clinical and experimental dermatology

authors： Markham T,Watson A,Rogers S

更新日期：2002-03-01 00:00:00

abstract：:Renal itch is localized or generalized itch, affecting patients with chronic renal failure, where there is no primary skin disease and no systemic or psychological dysfunction that might cause pruritus. It does not result from raised serum urea levels. The prevalence of renal itch has increased with the growing popula...

journal_title：Clinical and experimental dermatology

authors： Murphy M,Carmichael AJ

更新日期：2000-03-01 00:00:00

abstract：:The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

journal_title：Clinical and experimental dermatology

authors： Norris P,Bacon K,Bird C,Hawk J,Camp R

更新日期：1999-07-01 00:00:00

abstract：:Erosive pustular dermatosis (EPD) of the leg is an unusual form of amicrobial pustulosis, which typically affects elderly patients with chronic venous insufficiency. We report a patient who presented with painful erythema, crusted erosions and pustules on her right lower leg. Histology showed a dermal infiltration mad...

journal_title：Clinical and experimental dermatology

authors： Zhou Z,Zhang ZK,Liu TH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Data on the dermoscopic features of fungal melanonychia are limited. AIM:To identify the dermoscopic features of fungal melanonychia. METHODS:We reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past y...

journal_title：Clinical and experimental dermatology

authors： Kilinc Karaarslan I,Acar A,Aytimur D,Akalin T,Ozdemir F

更新日期：2015-04-01 00:00:00

abstract：:Mucocutaneous side-effects from etretinate are common and are usually dose-dependent, whereas hypersensitivity drug eruptions are rare. Two patients are described in whom erythema multiforme-like eruptions appeared several days after oral intake of etretinate. In one patient etretinate rechallenge again produced the s...

journal_title：Clinical and experimental dermatology

authors： David M,Sandbank M,Lowe NJ

更新日期：1989-05-01 00:00:00

abstract：:Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intrig...

journal_title：Clinical and experimental dermatology

authors： Sethuraman G,Srinivas CR,D'Souza M,Thappa DM,Smiles L

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:Studies have found that the interleukin-23/T helper 17 (IL-23/Th17) pathway plays an important role in the pathogenesis of atopic dermatitis (AD). Inhibition of the IL-23/Th17 pathway with monoclonal antibodies reduces skin inflammation in animal models. AIM:To investigate the association between IL-17A a...

journal_title：Clinical and experimental dermatology

authors： Narbutt J,Wojtczak M,Zalińska A,Salinski A,Przybylowska-Sygut K,Kuna P,Majak P,Sysa-Jedrzejowska A,Lesiak A

更新日期：2015-01-01 00:00:00

abstract：:We report a case of follicular porokeratosis of Mibelli affecting the natal cleft in a 42-year-old white man. To our knowledge, this is the first report in the English-language literature of follicular porokeratosis of Mibelli limited to the genitogluteal area. ...

journal_title：Clinical and experimental dermatology

authors： Yong AS,Singh M,Goulding JM,Swale VJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Skin-cancer screening should rely on simple, low-cost and high-sensitivity diagnostic procedures. AIMS:To compare diagnosis and management options after the evaluation of clinical and dermatoscopic teleconsultations with a store-and-forward teledermatology screening system for pigmented lesions. METHODS:Ka...

journal_title：Clinical and experimental dermatology

authors： Moreno-Ramirez D,Ferrandiz L,Galdeano R,Camacho FM

更新日期：2006-01-01 00:00:00

abstract：:Erythema multiforme (EM) is a common, self-limiting condition. Recurrent EM is a well-recognised variant, often associated with herpes simplex virus infection. It is frequently managed with prophylactic aciclovir. Anecdotal reports suggest that recurrent EM may be associated with the use of corticosteroids. Persistent...

journal_title：Clinical and experimental dermatology

authors： Turnbull N,Hawkins D,Atkins M,Francis N,Roberts N

更新日期：2014-03-01 00:00:00

abstract：:Melioidosis is a rare tropical disease caused by infection with the bacterium Burkholderia pseudomallei. It occurs predominantly in south-east Asia, northern and central Australia and central and south America. Patients often present to the internal medicine physicians with a severe, potentially fatal sepsis. We repor...

journal_title：Clinical and experimental dermatology

authors： Tran D,Tan HH

更新日期：2002-06-01 00:00:00

abstract：:Robert Willan is commemorated by a blue plaque on the house in which he lived in Bloomsbury Square in London. He lived there during a productive period of his career, until ill-health caused him to travel to Madeira, where he died. This fitting tribute to Willan is the result of the efforts of Dr. Henry MacCormac, him...

journal_title：Clinical and experimental dermatology

authors： Walker SL

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) occurs in 10-25% of unselected patients starting highly active antiretroviral therapy (HAART). About 52-78% of these cases involve cutaneous features. AIM:To describe the prevalence and incidence of new dermatological conditions within 6 months of patients ...

journal_title：Clinical and experimental dermatology

authors： Osei-Sekyere B,Karstaedt AS

更新日期：2010-07-01 00:00:00

abstract：:Mohs' surgery for basal cell carcinoma (BCC) is widely recommended by dermatologists as first line surgical therapy for recurrent or ill-defined skin tumours. The technique assumes that BCC spread by contiguous growth and that all tumour cells have to be removed. Advocates claim that Mohs' surgery provides a better ch...

journal_title：Clinical and experimental dermatology

authors： Lawrence CM

更新日期：1999-03-01 00:00:00

abstract：:We report the cases of two patients who developed generalized pustular psoriasis on the withdrawal of oral Cyclosporin treatment for persistent palmoplantar pustulosis. This complication does not appear to have been reported previously. ...

journal_title：Clinical and experimental dermatology

authors： De Silva BD,Benton EC,Tidman MJ

更新日期：1999-01-01 00:00:00

abstract：:Fourteen patients with psoriasis received long-term treatment with cyclosporin (CsA). Among patients there was great variability in the minimal effective CsA dose. In most patients long-term treatment was limited due to dose reductions made necessary because of side-effects. The therapeutic window for CsA seems small....

journal_title：Clinical and experimental dermatology

authors： Korstanje MJ,Van de Staak WJ

更新日期：1991-01-01 00:00:00

abstract：:We wish to report the progress of a patient with pyoderma faciale and Crohn's disease. The patient is interesting in that on two occasions the relapse in her skin condition coincided with the introduction of non-steroidal anti-inflammatory drugs. Therapy with isotretinoin was effective and well tolerated. ...

journal_title：Clinical and experimental dermatology

authors： McHenry PM,Hudson M,Smart LM,Rennie JA,Mowat NA,White MI

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Chronic cutaneous lesions affect 15% of human patients with diabetes, and the associated risk of limb amputations is 15-46 times greater than that of people with normal glycaemia. It is estimated that half of these limb amputations could be avoided by opportune treatment with somatic stem cells or platelet-r...

journal_title：Clinical and experimental dermatology

authors： Argôlo Neto NM,Del Carlo RJ,Monteiro BS,Nardi NB,Chagastelles PC,de Brito AF,Reis AM

更新日期：2012-07-01 00:00:00