Erosive pustular dermatosis of the leg mimicking lower limb cellulitis.


:Erosive pustular dermatosis (EPD) of the leg is an unusual form of amicrobial pustulosis, which typically affects elderly patients with chronic venous insufficiency. We report a patient who presented with painful erythema, crusted erosions and pustules on her right lower leg. Histology showed a dermal infiltration made up predominantly of neutrophils. Bacteria were isolated from the lesions. The condition was initially diagnosed as cellulitis, but antibiotic treatment was unsuccessful. After the correct diagnosis was made, complete resolution was obtained with betamethasone 0.05%.


Clin Exp Dermatol


Zhou Z,Zhang ZK,Liu TH




Has Abstract


2015-12-01 00:00:00












  • Disaccharide analysis of the skin glycosaminoglycans in patients with Werner's syndrome.

    abstract::The disaccharide content of the chondroitinase-digestible glycosaminoglycans (GAGs) extracted from 6-mm skin punch biopsies from the atrophic and sclerotic skin of two patients with Werner's syndrome (WS) were determined using high-performance liquid chromatography after 1-phenyl-3-methyl-5-pyrazolone labelling. The t...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Higuchi T,Ishikawa O,Hayashi H,Ohnishi K,Miyachi Y

    更新日期:1994-11-01 00:00:00

  • Allergic reactions to glyceryl trinitrate and isosorbide dinitrate demonstrating cross-sensitivity.

    abstract::Glyceryl trinitrate (nitroglycerin) has been in use for relief of angina for over a hundred years, but allergic reactions to it or to other organic nitrates rarely feature in the medical literature. Most of the case reports describe reactions to transdermally applied nitroglycerin. We report a case of a localized alle...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Aquilina S,Felice H,Boffa MJ

    更新日期:2002-11-01 00:00:00

  • Pemphigus vulgaris following a hyperimmune response to typhoid booster.

    abstract::We report the case of a 46-year-old Indian woman who developed a hyperimmune response to a typhoid booster injection in association with the development of pemphigus vulgaris. To our knowledge, this association has not previously been reported. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Bellaney GJ,Rycroft RJ

    更新日期:1996-11-01 00:00:00

  • Cutaneous calcinosis--an unusual complication of intravenous phosphate administration.

    abstract::The case of an 80-year-old woman who developed extensive cutaneous calcification following intravenous phosphate administration is presented. Also the circumstances under which cutaneous calcification may occur are discussed. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Mills CM,Knight AG

    更新日期:1993-07-01 00:00:00

  • Precalcaneal congenital fibrolipomatous hamartoma.

    abstract::Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a condition that is seldom reported in the paediatric literature and rarely in the dermatological literature. It has other disparate and confusing names and as histology is rarely obtained, the condition may be under-reported. We describe this disorder in the...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Flann S,Munn SE

    更新日期:2009-06-01 00:00:00

  • Circulating miR-142-3p levels in patients with systemic sclerosis.

    abstract:BACKGROUND:Recently, increased evidence has shown that serum micro (mi)RNA levels are a useful biomarker for the diagnosis, prognosis and therapeutic value of various diseases. However, serum miRNA has not been investigated in patients with systemic sclerosis (SSc), to our knowledge. AIM:To investigate the possibility...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Makino K,Jinnin M,Kajihara I,Honda N,Sakai K,Masuguchi S,Fukushima S,Inoue Y,Ihn H

    更新日期:2012-01-01 00:00:00

  • Management of nail psoriasis.

    abstract::Nail involvement is estimated to affect 80-90% of patients with psoriasis at some point in their lives and is often associated with severe disease. Patients with nail involvement experience pain, functional impairment and social stigma, with significant restriction of daily activities and quality of life. Nail psorias...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


    authors: Thomas L,Azad J,Takwale A

    更新日期:2021-01-01 00:00:00

  • Imiquimod 5% cream versus timolol 0.5% ophthalmic solution for treating superficial proliferating infantile haemangiomas: a retrospective study.

    abstract:BACKGROUND:Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM:To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS:The medical records of all the patients with p...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Qiu Y,Ma G,Yang J,Hu X,Chen H,Jin Y,Lin X

    更新日期:2013-12-01 00:00:00

  • Scoring the proliferative activity of haemangioma of infancy: the Haemangioma Activity Score (HAS).

    abstract:BACKGROUND:Haemangioma of infancy (HOI) is the most frequently occurring benign tumour of infancy. A good, reliable and objective scoring system for haemangioma activity is not yet available. AIM:We have developed a simple system called the Haemangioma Activity Score (HAS) for scoring the (disease) proliferative activ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Janmohamed SR,de Waard-van der Spek FB,Madern GC,de Laat PC,Hop WC,Oranje AP

    更新日期:2011-10-01 00:00:00

  • Tumoral calcinosis: an unusual cause of cutaneous calcification.

    abstract::Tumoral calcinosis is an uncommon ectopic calcification syndrome characterized clinically by the presence of irregular, painless, periarticular soft tissue calcifying masses, and pathologically by fibrous-walled cystic spaces containing structureless calcific debris and associated with a variable inflammatory reaction...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Harwood CA,Cook MG,Mortimer PS

    更新日期:1996-03-01 00:00:00

  • A rare case of recessive dystrophic epidermolysis bullosa and verruciform xanthoma.

    abstract::A 33-year-old man with recessive dystrophic epidermolysis bullosa presented with a 3-month history of an enlarging mass within scarring on the posterior aspect of the right shoulder. The clinical appearance of the mass with an almost cobbled, verrucous surface, and its rapid evolution suggested the development of a sq...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Orpin SD,Scott IC,Rajaratnam R,Colloby PS,Heagerty A

    更新日期:2009-01-01 00:00:00

  • Familial Jessner's lymphocytic infiltration of the skin, occurring in a father and daughter.

    abstract::Familial occurrence of Jessner's lymphocytic infiltration of the skin is reported in a father and daughter. A definitive diagnosis of Jessner's disease was greatly facilitated by the presence of large numbers of plasmacytoid monocytes within the dermal infiltrates in both patients. A role for skin-directed lymphocyte ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Toonstra I,van der Putte SC,de la Faille HB,van Vloten WA

    更新日期:1993-03-01 00:00:00

  • An observational analysis of low-dose thalidomide in recalcitrant prurigo nodularis.

    abstract::Thalidomide has been used as an effective treatment for prurigo nodularis (PN) with a median dose of 200 mg, but the risk of peripheral neuropathy precludes long-term use. We analysed the efficacy of low-dose thalidomide (< 100 mg) in 17 patients with recalcitrant PN. Patients were initiated on thalidomide 50 mg on al...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Sardana K,Gupta A,Sinha S

    更新日期:2020-01-01 00:00:00

  • Ceramide profile in hypohidrotic ectodermal dysplasia.

    abstract:BACKGROUND:Hypohidrotic ectodermal dysplasia (HED) is a rare genetic disease. The clinical presentation includes lack of sweating ability, and an often widely spread dermatitis resembling atopic dermatitis (AD). In AD, the skin-barrier defect is partly ascribed to the altered lipid profile in the stratum corneum and pa...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Jungersted JM,Høgh JK,Hellgren LI,Agner T,Jemec GB

    更新日期:2012-03-01 00:00:00

  • Bullous secondary syphilis.

    abstract::An earlier standard syphilology textbook states that 'If vesicles are an essential part of an eruption in an adult, the lesions are not due to secondary syphilis'. However, vesicular and bullous eruptions do occur in congenital syphilis and rare reports of both vesicular and pustular eruptions in adults with secondary...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Lawrence P,Saxe N

    更新日期:1992-01-01 00:00:00

  • The course of pregnancy and childbirth in three mothers with recessive dystrophic epidermolysis bullosa.

    abstract:BACKGROUND:Recessive dystrophic epidermolysis bullosa (RDEB) is an autosomal recessive skin disease caused by mutations in the type VII collagen gene (COL7A1), resulting in detachment of the entire epidermis due to loss or hypoplasticity of the anchoring fibrils that normally secure the basement membrane to the underly...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Hanafusa T,Tamai K,Umegaki N,Yamaguchi Y,Fukuda S,Nishikawa Y,Yaegashi N,Okuyama R,McGrath JA,Katayama I

    更新日期:2012-01-01 00:00:00

  • Natural progression of male pattern baldness in young men.

    abstract::Twenty-six men who presented with male pattern baldness (androgen-dependent alopecia), were quantitatively evaluated for scalp hair variables and compared with 13 age-matched controls. Compared to controls, significant mean differences for hair variables were found in the frontal-vertex area, while in the occipital ar...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Rushton DH,Ramsay ID,Norris MJ,Gilkes JJ

    更新日期:1991-05-01 00:00:00

  • Health-related quality of life among patients with facial acne -- assessment of a new acne-specific questionnaire.

    abstract::The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne th...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Martin AR,Lookingbill DP,Botek A,Light J,Thiboutot D,Girman CJ

    更新日期:2001-07-01 00:00:00

  • Liposuction for axillary hyperhidrosis.

    abstract::A 23-year-old woman presented with a 10 year history of excessive sweating (hyperhidrosis), mostly in the axillae, and to a lesser extent the groin and hands. Initial treatment with a sedative antihistamine and topical Driclor (aluminium chloride hexahydrate in 2% alcohol) for 14 weeks resulted in no improvement. Axil...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Payne CM,Doe PT

    更新日期:1998-01-01 00:00:00

  • Keratolytic winter erythema with facial involvement: a novel presentation.

    abstract::We present a 23-year-old woman with a diagnosis of keratolytic winter erythema (erythrokeratolysis hiemalis), who developed facial lesions following a traumatic experience. This rare genodermatosis usually affects the palms and soles, and appears as mild erythema and annular scaling. The limbs and trunk can rarely be ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Degiovanni CV,Farrant PB,Howell S,Hull PR,Woollons A

    更新日期:2009-03-01 00:00:00

  • Cutaneous involvement in an 8-year-old boy with Ras-associated autoimmune leucoproliferative disorder (RALD).

    abstract::Ras-associated autoimmune leucoproliferative disorder (RALD) is a nonmalignant syndrome associated with somatic KRAS mutations. We report a patient with RALD and cutaneous lesions, the first such case reported, to our knowledge. An 8-year-old boy presented with erythematous plaques on his face and body, along with lym...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Giacaman A,Bauzá Alonso A,Salinas Sanz JA,Dapena Díaz JL,Ramos Asensio R,Ferrés Ramis L,Durán Pastor MA,Martín-Santiago A

    更新日期:2018-12-01 00:00:00

  • Comparative efficacy of drug regimens in skin tuberculosis.

    abstract::Three antituberculous drug regimens have been employed to study the therapeutic response in 90 patients with any one of the commonly encountered paucibacillary forms of skin tuberculosis, namely lupus vulgaris, tuberculosis verrucosa cutis and scrofuloderma. The first two regimens contained rifampicin, isoniazid and e...

    journal_title:Clinical and experimental dermatology

    pub_type: 临床试验,杂志文章


    authors: Ramesh V,Misra RS,Saxena U,Mukherjee A

    更新日期:1991-03-01 00:00:00

  • Accumulation of membrane-bound melanosomes occurs in Langerhans cells of patients with the Leopard syndrome.

    abstract::The Langerhans cells in the lentigines of four patients with the Leopard syndrome contained large membrane bound accumulations of melanin granules. Giant melanosomes were only seen in two patients. The patients had no immune-based symptoms relating to their lentigines. The Leopard Syndrome, also known as multiple lent...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Fryer PR,Pope FM

    更新日期:1992-01-01 00:00:00

  • Lichenoid keratosis is frequently misdiagnosed as basal cell carcinoma.

    abstract::Lichenoid keratosis (LK), also known as benign lichenoid keratosis or lichen planus-like keratosis, is a solitary, pink to red-brown scaly plaque representing a host immunological response to a variety of precursor lesions. LK is often misdiagnosed as a dermatological malignancy owing to its clinical resemblance to ba...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Maor D,Ondhia C,Yu LL,Chan JJ

    更新日期:2017-08-01 00:00:00

  • Association of angiopoietin-1, angiopoietin-2 and caspase-5 polymorphisms with psoriasis vulgaris.

    abstract:BACKGROUND:Psoriasis involves a multifaceted interplay of keratinocytes, blood vessels, immune system mediators and expressed genes. AIM:To determine whether genetic polymorphisms in the angiopoietin-1 (ANGPT1), angiopoietin-2 (ANGPT2) and caspase-5 (CASP5) genes are associated with an increased risk of developing pso...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: He L,Dang L,Zhou J,Bai J,Li YZ

    更新日期:2015-07-01 00:00:00

  • A case of dermatopathia pigmentosa reticularis with wiry scalp hair and digital fibromatosis resulting from a recurrent KRT14 mutation.

    abstract::We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarrin...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Goh BK,Common JE,Gan WH,Kumarasinghe P

    更新日期:2009-04-01 00:00:00

  • What's new in atopic eczema? An analysis of systematic reviews published in 2010-11.

    abstract::This review provides a summary of key findings from 24 systematic reviews of atopic eczema (AE) published or indexed between 1 August 2010 and 31 December 2011, updating published summaries from previous years. Epidemiological evidence points to the protective effects of early daycare, endotoxin exposure, consumption ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


    authors: Torley D,Futamura M,Williams HC,Thomas KS

    更新日期:2013-07-01 00:00:00

  • 'Wake sign': an important clue for the diagnosis of scabies.

    abstract::Japan is currently experiencing many outbreaks of scabies, occurring mainly in long-term care facilities. Scabies burrows, the only pathognomonic lesion for scabies, often occur on the creases of the palms, and are followed by a pattern of scale reminiscent of the 'wake' left on the surface of water by a moving bird o...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Yoshizumi J,Harada T

    更新日期:2009-08-01 00:00:00

  • Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole.

    abstract::Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficienc...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章


    authors: Toms-Whittle LM,John LH,Buckley DA

    更新日期:2011-04-01 00:00:00

  • Mechanisms of photodamage of the skin and its functional consequences for skin ageing.

    abstract::Chronic photodamage of the skin manifests itself as extrinsic skin ageing (photoageing) and photocarcinogenesis. DNA photodamage and UV-generated reactive oxygen species are the initial molecular events that lead to most of the typical histological and clinical manifestations of chronic photodamage of the skin. Knowle...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审


    authors: Trautinger F

    更新日期:2001-10-01 00:00:00