Systemic polyarteritis nodosa mimicking pyoderma gangrenosum in a rare association with small lymphocytic leukaemia/chronic lymphocytic leukaemia.

abstract：:Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per da...

journal_title：Clinical and experimental dermatology

authors： Tan A,Tan HH,Lee CC,Ng SK

更新日期：2003-05-01 00:00:00

abstract：:Loceryl nail lacquer was developed to provide the effective antifungal drug, amorolfine, in a once-weekly dosage regimen combined with a convenient mode of application. Traditional formulations such as creams and nail solutions do not fulfil these requirements because they are wiped or washed off very rapidly. Amorolf...

journal_title：Clinical and experimental dermatology

authors： Pittrof F,Gerhards J,Erni W,Klecak G

更新日期：1992-09-01 00:00:00

abstract：:Intravenous (IV) calcium is usually given to temporarily treat the effects of hyperkalaemia on muscle and heart. When extravasation of a calcium gluconate infusion occurs, there may be rapid and marked swelling and erythema, with signs of soft-tissue necrosis or infection, and ensuing extensive local calcification, ca...

journal_title：Clinical and experimental dermatology

authors： Celbek G,Gungor A,Albayrak H,Kir S,Guvenc SC,Aydin Y

更新日期：2013-03-01 00:00:00

abstract：:Treatment of autoimmune blistering diseases consists of systemic glucocorticosteroids usually in combination with additional immunosuppressants such as azathioprine and mycophenolate mofetil or immunomodulators such as dapsone, antibiotics, intravenous immunoglobulins, and immunoadsorption. In some patients, these tre...

journal_title：Clinical and experimental dermatology

authors： Schmidt E,Hunzelmann N,Zillikens D,Bröcker EB,Goebeler M

更新日期：2006-07-01 00:00:00

abstract：:Refractory leg ulcers in two patients healed following splenectomy. Neither patient had the ethnic background or family history of haematological abnormalities to suggest a haemoglobinopathy. ...

journal_title：Clinical and experimental dermatology

authors： Lawrence P,Aronson I,Saxe N,Jacobs P

更新日期：1991-01-01 00:00:00

abstract：:Hydroa vacciniforme (HV) is a rare photodermatosis first described by Bazin in the mid-nineteenth century. It typically presents in childhood and resolves during adolescence. Rarely, however, symptoms may persist into adult life.2,3 We now describe a patient with this condition presenting unusually for the first time ...

journal_title：Clinical and experimental dermatology

authors： Blackwell V,McGregor JM,Hawk JL

更新日期：1998-03-01 00:00:00

abstract：:There is variation in the treatment of lower limb cellulitis (LLC) with no agreement on the most effective antibiotic regimen. Many patients with cellulitis fail to respond to first-line antibiotics. This can negatively affect patient care and result in unnecessary hospital admissions. The aim of this systematic revie...

journal_title：Clinical and experimental dermatology

authors： Mistry K,Sharma S,Patel M,Grindlay D,Janjuha R,Smart P,Levell NJ

更新日期：2021-01-01 00:00:00

abstract：:Although Q-switched (QS) lasers are the mainstay of modern tattoo removal, paradoxical darkening of tattoo ink may occur. This darkening of tattoo ink is dependent on laser wavelength, pulse duration and fluence, with high-energy, nanosecond-pulsed lasers more prone to induce tattoo-ink darkening. Laser toning, consis...

journal_title：Clinical and experimental dermatology

authors： Chung WK,Yang JH,Lee DW,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2009-12-01 00:00:00

abstract：AIM:To evaluate the effectiveness of a silicone gel in treating surgical wounds compared with a control group of the same phenotype and same scar site for which a placebo was advised. METHODS:This was a randomized controlled trial, carried out in a dermatology department of a university hospital. In total, we studied ...

journal_title：Clinical and experimental dermatology

authors： de Giorgi V,Sestini S,Mannone F,Papi F,Alfaioli B,Gori A,Lotti T

更新日期：2009-08-01 00:00:00

abstract：:The effect of Anandron, a novel non-steroidal anti-androgen, on the reduction in sexual hair growth of 14 male-to-female transsexuals was investigated. Anandron (300 mg/day) alone for 8 weeks increased serum testosterone levels (mean: 19.2 +/- 6.1 to 44.9 +/- 11.5 mmol/l) and serum oestradiol levels (mean: 0.08 +/- 0....

journal_title：Clinical and experimental dermatology

authors： Asscheman H,Gooren LJ,Peereboom-Wynia JD

更新日期：1989-09-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease originating from the pilosebaceous unit, in which patients develop painful abscesses, sinus tracts, nodules and scarring, typically in intertriginous areas. Major gaps in our understanding of HS exist, and these may be partially due to the lack of an...

journal_title：Clinical and experimental dermatology

authors： Quartey QQ,Miller RJ,Pinsker BL,Okoh UJ,Shipman WD,George BA,Nwizu CC,Barnes LA,Kerns ML,Caffrey JA,Aliu O,Brown ID,Succaria F,Maynard JP,Herbert AS,Kang S,Miller LS,Okoye GA,Byrd AS

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：:We report a man with a 3-year-history of a striking eruption of small, 2-3 mm diameter keratotic, crateriform papules distributed symmetrically over the lower limbs. Morphologically the individual papules closely resembled those described in acrokeratoelastoidosis (AK) of Costa and in focal acral hyperkeratosis of Dow...

journal_title：Clinical and experimental dermatology

authors： Helbling I,Tucker SC,Chalmers RJ

更新日期：2001-05-01 00:00:00

abstract：:The clinical characteristics associated with hidradenitis suppurativa (HS) severity are poorly understood. In this study, 124 patients with HS from 6 Italian dermatology centres participated in this study. Disease severity was assessed using the Hidradenitis Suppurativa Physician's Global Assessment score (HS-PGA) and...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Caposiena Caro RD,Ganzetti G,Molinelli E,Dini V,Oranges T,Romanelli M,Fabbrocini G,Monfrecola G,Napolitano M,Egan CG,Musumeci ML,Lacarrubba F,Micali G,Passoni E,Calzavara-Pinton PG,Venturini M,Zanca A,Offida

更新日期：2019-07-01 00:00:00

abstract：:Majocchi's granuloma, also known as nodular granulomatous perifolliculitis, is an uncommon fungal infection of the skin and subcutaneous tissue. It can occur in healthy and immunocompromised patients. The most common cause of Majocchi's granuloma is Trichophyton rubrum. We report a case of a Majocchi's granuloma cause...

journal_title：Clinical and experimental dermatology

authors： Saadat P,Kappel S,Young S,Abrishami M,Vadmal MS

更新日期：2008-07-01 00:00:00

abstract：:Ten psoriatic patients were treated with an accelerated PUVA regimen. Nine patients cleared in an average of 13.7 treatments (range 4-24) after an average total UVA dose of 83 J/cm2 (range 18-186). One patient had to withdraw due to pruritus and burning and six others had burning problems. The high incidence of burnin...

journal_title：Clinical and experimental dermatology

authors： Green C,George S,Lakshmipathi T,Ferguson J

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an organ-specific autoimmune disease characterized by folliculotropic T-cell infiltrates around anagen-stage hair follicles. The role of T helper (Th)1 and Th2 cytokines in the pathogenesis of AA have not been established. AIM:To determine whether serum cytokine profiles define the s...

journal_title：Clinical and experimental dermatology

authors： Barahmani N,Lopez A,Babu D,Hernandez M,Donley SE,Duvic M

更新日期：2010-06-01 00:00:00

abstract：:Systemic sclerosis (SSc) is often complicated by severe skin ulcers that are unresponsive to traditional treatments. Vascular alterations are responsible for the ischaemic features of the disease in both the skin and visceral organs. Defective neoangiogenesis correlates with an abnormally reduced quantity of circulati...

journal_title：Clinical and experimental dermatology

authors： Ferri C,Giuggioli D,Manfredi A,Quirici N,Scavullo C,Colaci M,Gianelli U,Deliliers GL,Del Papa N

更新日期：2010-12-01 00:00:00

abstract：:Photodynamic therapy (PDT) with topical 5-aminolaevulinic acid (5-ALA) is a promising new treatment for superficial malignant nonmelanoma tumours, including cutaneous malignant lymphoma. Here, we report a case of cutaneous anaplastic large cell lymphoma effectively treated by PDT with topical 5-ALA in combination with...

journal_title：Clinical and experimental dermatology

authors： Umegaki N,Moritsugu R,Katoh S,Harada K,Nakano H,Tamai K,Hanada K,Tanaka M

更新日期：2004-01-01 00:00:00

abstract：:Angiogenesis plays an important role in progression of various tumours including malignant melanoma. It is possible that the immunostaining of angiogenic markers could differentiate benign and malignant melanocytic lesions or that the immunostaining pattern with angiogenic markers could vary with tumour thickness and ...

journal_title：Clinical and experimental dermatology

authors： Dawn G,MacKie RM

更新日期：2002-03-01 00:00:00

abstract：:Acquired cold urticaria (ACU) is a frequent subtype of physical urticaria that is caused by the release of proinflammatory mast cell mediators after cold exposure. Although the underlying causes of ACU still remain to be clarified in detail, a wide range of diseases has been reported to be associated with ACU. This re...

journal_title：Clinical and experimental dermatology

authors： Siebenhaar F,Weller K,Mlynek A,Magerl M,Altrichter S,Vieira Dos Santos R,Maurer M,Zuberbier T

更新日期：2007-05-01 00:00:00

abstract：:Ichthyosis hystrix, Curth-Macklin type (IHCM) is an extremely rare autosomal dominant dermatosis caused by mutations in the keratin genes, KRT1 or KRT10, which often manifests as extensive, dark, spiky or verrucous plaques and severe palmoplantar keratoderma. We report a novel frameshift truncation mutation, c.1596_15...

journal_title：Clinical and experimental dermatology

authors： Yang Z,Xu Z,Zhang N,Ma L

更新日期：2020-08-01 00:00:00

abstract：:Graham Little-Piccardi-Lassueur syndrome (GLPLS) is a rare lichenoid dermatosis defined by scarring alopecia, loss of pubic and axillary hairs and progressive development of horny follicular papules variously located. Topical or systemic corticosteroids, retinoids or PUVA therapy are the treatments usually proposed an...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Paro Vidolin A,Piemonte P,Carboni I,Chimenti S

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:In patients with psoriasis, videocapillaroscopy has been used to visualize the typical modifications in the microcirculatory architecture. AIM:To evaluate the modifications of the superficial capillary bed in a psoriatic plaque and healthy perilesional skin during treatment with a topical steroid. METHODS:...

journal_title：Clinical and experimental dermatology

authors： Stinco G,Lautieri S,Piccirillo F,Valent F,Patrone P

更新日期：2009-12-01 00:00:00

abstract：:Neurotrophic ulceration of the face is a rare but well recognized sequel to division of the trigeminal nerve. Trauma is an important contributory factor and thought to be due in part to paraesthesiae, which encourages picking and scratching, with resultant chronic and persistent ulceration. A case is described of an 8...

journal_title：Clinical and experimental dermatology

authors： Mayer RD,Smith NP

更新日期：1993-03-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma of the skin, usually occurring at sun-exposed sites in elderly people. Divergent differentiation in MCC, although rare, has been reported in previous case series. We describe two new cases of MCC with divergent differentiation. Patient 1 was a 96-y...

journal_title：Clinical and experimental dermatology

authors： Gaitskell K,Nassar S,Ibrahim H

更新日期：2020-04-01 00:00:00

abstract：:The use of an aqueous solution of 0.5% topical glycopyrollate was effective in the treatment of hyperhidrosis of the scalp and forehead after other treatments had proved ineffective; this appears to be the first report of its use in this condition. ...

journal_title：Clinical and experimental dermatology

authors： Seukeran DC,Highet AS

更新日期：1998-09-01 00:00:00

abstract：:Although Fabry disease (FD) is an X-linked lysosomal storage disorder, there is a high prevalence of affected heterozygous females who show symptoms and have an increased mortality associated with the disease. FD usually progresses slowly, and death can result from stroke, heart disease or renal failure. Diagnosis can...

journal_title：Clinical and experimental dermatology

authors： Hogarth V,Hughes D,Orteu CH

更新日期：2013-03-01 00:00:00

abstract：:Ten patients with plaque-type psoriasis were treated by applying semi-permeable hydrocolloid dressings (Com-feel, Coloplast, Denmark) and the effect compared to untreated skin. The treatment effect was evaluated by: (a) O2-consumption as measured by a TCM-2 oxygen-monitor; (b) blood flow as measured by laser-Doppler f...

journal_title：Clinical and experimental dermatology

authors： Broby-Johansen U,Kristensen JK

更新日期：1989-07-01 00:00:00

abstract：:We describe the case of a 68-year-old woman who presented with asymptomatic skin nodules and symptoms of anaemia, and was found to have acute megakaryoblastic leukaemia with fibrosis, a condition now believed to correspond to the former diagnosis of acute myelofibrosis. There is only one previous report of skin lesion...

journal_title：Clinical and experimental dermatology

authors： Macfarlane AW,Parry DH,Caslin AW,Hughes M

更新日期：1996-05-01 00:00:00