Abstract：
:Neurotrophic ulceration of the face is a rare but well recognized sequel to division of the trigeminal nerve. Trauma is an important contributory factor and thought to be due in part to paraesthesiae, which encourages picking and scratching, with resultant chronic and persistent ulceration. A case is described of an 82-year-old woman with severe trigeminal neurotrophic ulceration which improved substantially with pimozide, given for treatment of unrelated paranoid symptoms. The possible relevance of this to the established use of pimozide in delusional parasitosis is briefly discussed.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Mayer RD,Smith NPdoi
10.1111/j.1365-2230.1993.tb01007.xsubject
Has Abstractpub_date
1993-03-01 00:00:00pages
171-3issue
2eissn
0307-6938issn
1365-2230journal_volume
18pub_type
杂志文章abstract：:Osteoporosis has been observed with chronic hypervitaminosis A, leading some authors to hypothesize that systemic retinoids may have an effect on bone mineral density. Two previous small studies identified osteoporosis in patients who received long-term therapy with etretinate. Etretinate has now been superceeded by a...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-2230.2003.01265.x
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Previous studies have shown that concomitant administration of food may enhance the bioavailability of oral retinoids. AIM:To assess the influence of food on the pharmacokinetics (PK) of alitretinoin after a single oral dose. METHODS:This was a single-dose, open-label, randomized, crossover study, which en...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1365-2230.2011.04033.x
更新日期：2011-04-01 00:00:00
abstract：:A case of pure non-epidermotropic cutaneous lymphoma in a human immunodeficiency virus-infected patient is reported following a viral opportunistic infection [cytomegalovirus (CMV) hepatitis]. The lymphoid infiltrate was Epstein-Barr virus and CMV negative with a CD30-positive T-cell phenotype. Molecular analysis demo...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：:Myiasis is a condition resulting from the invasion of tissues or organs of man or animals by the larvae of dipterous flies. The distribution of myiasis is worldwide, with more cases being reported from tropical, subtropical, and warm temperate areas. The various forms of myiasis may be classified from an entomological...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-2230.1999.00479.x
更新日期：1999-07-01 00:00:00
abstract：:We performed an immunohistochemical study with 11 antikeratin antibodies using the newly developed AMeX (acetone-methylbenzoate-xylene) tissue processing method. Specimens processed with this method showed almost as good preservation and morphological detail as routinely processed, formalin-fixed and paraffin-embedded...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.1994.tb01247.x
更新日期：1994-11-01 00:00:00
abstract：:Melkersson-Rosenthal syndrome (MRS) is an uncommon, complex neuromucocutaneous disorder characterized by recurrent orofacial oedema, facial palsy and fissured tongue. Complete MRS is uncommon. A case of complete MRS with multiple cranial nerve palsies is reported. ...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2009.03418.x
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Vitiligo is a pigmentation disorder of autoimmune aetiology. Polymorphisms in beta-defensin genes have been linked to a predisposition to some autoimmune disorders. AIM:To evaluate the role of polymorphisms in DEFB1, the gene encoding for human beta-defensin (HBD)-1 and its 5' untranslated region in nonsegm...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/ced.13697
更新日期：2019-04-01 00:00:00
abstract：:Hydroxyurea is an anti-tumour agent most commonly used to treat chronic myeloproliferative disorders in doses up to 4 g per day. Dermatological adverse effects reported so far have been observed predominantly in these patients. As we are treating selected psoriasis patients with low dose hydroxyurea we attempted to de...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1046/j.0307-6938.2001.00947.x
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Acne vulgaris is a common skin problem that affects up to 90% of adolescents. Colonization of the duct with Propionibacterium species is one of the factors implicated in the development of acne. Owing to the increasing incidence of antibiotic resistance, there has been an greater interest in the development ...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1365-2230.2007.02472.x
更新日期：2007-11-01 00:00:00
abstract：:Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy the aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition th...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-2230.1999.00510.x
更新日期：1999-09-01 00:00:00
abstract：:Mohs' surgery for basal cell carcinoma (BCC) is widely recommended by dermatologists as first line surgical therapy for recurrent or ill-defined skin tumours. The technique assumes that BCC spread by contiguous growth and that all tumour cells have to be removed. Advocates claim that Mohs' surgery provides a better ch...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章,评审
doi：10.1046/j.1365-2230.1999.00433.x
更新日期：1999-03-01 00:00:00
abstract：:Photodynamic therapy (PDT) with topical 5-aminolaevulinic acid (5-ALA) is a promising new treatment for superficial malignant nonmelanoma tumours, including cutaneous malignant lymphoma. Here, we report a case of cutaneous anaplastic large cell lymphoma effectively treated by PDT with topical 5-ALA in combination with...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2004.01448.x
更新日期：2004-01-01 00:00:00
abstract：:A 72-year-old woman with a 14-year history of urticarial vasculitis (UV) and a 13-year history of bullous pemphigoid (BP) presented with associated progressive chronic lymphocytic leukaemia (CLL). Both skin conditions responded poorly to treatment, until chemotherapy for CLL was commenced. The skin features showed a c...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/ced.12553
更新日期：2015-06-01 00:00:00
abstract：:Majocchi's granuloma, also known as nodular granulomatous perifolliculitis, is an uncommon fungal infection of the skin and subcutaneous tissue. It can occur in healthy and immunocompromised patients. The most common cause of Majocchi's granuloma is Trichophyton rubrum. We report a case of a Majocchi's granuloma cause...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2007.02623.x
更新日期：2008-07-01 00:00:00
abstract：:We wish to report the progress of a patient with pyoderma faciale and Crohn's disease. The patient is interesting in that on two occasions the relapse in her skin condition coincided with the introduction of non-steroidal anti-inflammatory drugs. Therapy with isotretinoin was effective and well tolerated. ...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.1992.tb00262.x
更新日期：1992-11-01 00:00:00
abstract：:An essential property of the immune system is its ability to generate diverse antibody and T-cell mediated responses to virtually any potential foreign particle. The basic molecular mechanisms responsible for producing this extensive diversity have now been elucidated. Each T cell expresses a unique membrane bound T-c...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章,评审
doi：
更新日期：1996-03-01 00:00:00
abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2010.04006_1.x
更新日期：2011-03-01 00:00:00
abstract：:Porphyria cutanea tarda (PCT) is believed to be associated with reduced hepatic uroporphyrinogen decarboxylase activity and risk factors such as alcohol abuse and medication with oral contraceptives and certain other drugs. Recently it has been suggested that hepatitis C virus (HCV) infection may also be associated wi...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.1996.tb00095.x
更新日期：1996-07-01 00:00:00
abstract：:Recent studies have shown that the protein MIA (melanoma inhibitory activity) is a potent serum marker for malignant melanoma. MIA is expressed in chondrocytes at high levels, and might potentially be elevated during periods of growth in childhood. Therefore, we evaluated MIA serum levels in pregnant women and in grow...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2004.01623.x
更新日期：2004-11-01 00:00:00
abstract：:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. We report a case in which identical T-cell clones were identified in both patch and tumour stage lesions and in which the tumorous deposits, containing CD30-positive cells, regressed spontaneously. We discuss the differential diagnosis of the tumorou...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:We describe the case of a 37-year-old female with a history of psoriasiform dermatitis who presented with multicentric primary cutaneous CD30-positive anaplastic large T cell lymphoma (ALCL). Despite aggressive systemic therapy, the patient suffered multiple relapses and the lymphoma spread to cervical and inguinal ly...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-2230.2003.01406.x
更新日期：2003-11-01 00:00:00
abstract：:The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...
journal_title：Clinical and experimental dermatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1365-2230.1990.tb02067.x
更新日期：1990-05-01 00:00:00
abstract：:Complete deficiency of the fourth component of complement (C4) is an extremely rare condition. However, it has been reported that partial C4 deficiency can occur in normal subjects, and is associated with several immune diseases. We report a 44-year-old woman who developed slight oedema and punctate purpura on her low...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2012.04423.x
更新日期：2013-07-01 00:00:00
abstract：:Many types of histiocytoses have been described. We present a case of a 56-year-old woman who presented with multiple nodules on the hands. On histological examination of an excision biopsy, a mainly dermal lesion was seen, with scattered mononuclear inflammatory cells and occasional multinucleated cells in the backgr...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2011.04207.x
更新日期：2012-04-01 00:00:00
abstract：:We report a case of drug reaction with eosinophilia and systemic symptoms (DRESS) to efalizumab. A 52-year-old man developed a widespread papulovesicular rash after 4 weeks of treatment with efalizumab (1.0 mg/kg/week) for treatment-resistant severe psoriasis. Histology revealed a subepidermal blister with eosinophil-...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2007.02604.x
更新日期：2008-01-01 00:00:00
abstract：:It is well known that systemic corticosteroids arrest the progress of vitiligo and lead to repigmentation, but they may produce unacceptable side-effects. The use of high-dose prednisolone therapy to minimize the side-effects of systemic steroids has been reported, but there have been no reports on the effectiveness o...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.2007.02387.x
更新日期：2007-09-01 00:00:00
abstract：:Familial occurrence of Jessner's lymphocytic infiltration of the skin is reported in a father and daughter. A definitive diagnosis of Jessner's disease was greatly facilitated by the presence of large numbers of plasmacytoid monocytes within the dermal infiltrates in both patients. A role for skin-directed lymphocyte ...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.1993.tb00996.x
更新日期：1993-03-01 00:00:00
abstract：:The case of an 80-year-old woman who developed extensive cutaneous calcification following intravenous phosphate administration is presented. Also the circumstances under which cutaneous calcification may occur are discussed. ...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.1993.tb02221.x
更新日期：1993-07-01 00:00:00
abstract：BACKGROUND:The dorsum of the hand is a common site for squamous cell carcinoma, and excision with appropriate margins often results in surgical defects that cannot be repaired by primary side-to-side closure. AIM:To assess healing time, complications and resulting scars when surgical wounds on the dorsum of the hand w...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/ced.12044
更新日期：2013-08-01 00:00:00
abstract：:A 59-year-old woman with a single cuff-like plaque, consisting of multiple skin-coloured to bluish cysts and comedones on her right forearm is reported. The solitary lesion resembled, morphologically and histologically, the Favre-Racouchot syndrome. The above condition is another case of the previously described actin...
journal_title：Clinical and experimental dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-2230.1993.tb02181.x
更新日期：1993-05-01 00:00:00
