Co-existent primary cutaneous anaplastic large cell lymphoma and lymphomatoid papulosis.

Abstract:

:We describe the case of a 37-year-old female with a history of psoriasiform dermatitis who presented with multicentric primary cutaneous CD30-positive anaplastic large T cell lymphoma (ALCL). Despite aggressive systemic therapy, the patient suffered multiple relapses and the lymphoma spread to cervical and inguinal lymph nodes. Later in her clinical course it was appreciated that she was also suffering from lymphomatoid papulosis (LyP). The case illustrates the overlapping clinical, histological and immunophenotypic features of ALCL and LyP, conditions which represent a spectrum of CD30-positive lymphoproliferative disease. A multidisciplinary approach between dermatologist, oncologist and pathologist is essential for the optimal management of these complex conditions.

journal_name

Clin Exp Dermatol

authors

Dawn G,Morrison A,Morton R,Bilsland D,Jackson R

doi

10.1046/j.1365-2230.2003.01406.x

keywords:

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

620-4

issue

6

eissn

0307-6938

issn

1365-2230

pii

1406

journal_volume

28

pub_type

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