Abstract:
:We describe the case of a 37-year-old female with a history of psoriasiform dermatitis who presented with multicentric primary cutaneous CD30-positive anaplastic large T cell lymphoma (ALCL). Despite aggressive systemic therapy, the patient suffered multiple relapses and the lymphoma spread to cervical and inguinal lymph nodes. Later in her clinical course it was appreciated that she was also suffering from lymphomatoid papulosis (LyP). The case illustrates the overlapping clinical, histological and immunophenotypic features of ALCL and LyP, conditions which represent a spectrum of CD30-positive lymphoproliferative disease. A multidisciplinary approach between dermatologist, oncologist and pathologist is essential for the optimal management of these complex conditions.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Dawn G,Morrison A,Morton R,Bilsland D,Jackson Rdoi
10.1046/j.1365-2230.2003.01406.xkeywords:
subject
Has Abstractpub_date
2003-11-01 00:00:00pages
620-4issue
6eissn
0307-6938issn
1365-2230pii
1406journal_volume
28pub_type
杂志文章abstract::The effectiveness of EMLA cream in relieving the discomfort associated with percutaneous infiltration of lignocaine was assessed in a double-blind, placebo-controlled study. Patients undergoing minor skin surgery were divided into two groups, according to the number of lesions requiring surgery. The first group had a ...
journal_title:Clinical and experimental dermatology
pub_type: 临床试验,杂志文章,随机对照试验
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