Dermoscopic features of naevus-associated melanoma.

abstract：:Dystrophic epidermolysis bullosa (DEB) is caused by mutations in the COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils. The characteristic genetic lesion in dominant DEB (DDEB) is a glycine substitution in the collagenous domain of the protein. In this study, we identified a Chinese fami...

journal_title：Clinical and experimental dermatology

authors： Zhang XJ,Song YX,Zhang XQ,Yang S,Li M,Li CR,Yang CJ,Yang J

更新日期：2003-07-01 00:00:00

abstract：:A case of pure non-epidermotropic cutaneous lymphoma in a human immunodeficiency virus-infected patient is reported following a viral opportunistic infection [cytomegalovirus (CMV) hepatitis]. The lymphoid infiltrate was Epstein-Barr virus and CMV negative with a CD30-positive T-cell phenotype. Molecular analysis demo...

journal_title：Clinical and experimental dermatology

authors： Viraben R,Brousset P,Aquilina C,Lamant L

更新日期：1997-11-01 00:00:00

abstract：:We present a case of neonatal lupus erythematosus (NLE) in a black infant presenting with symmetrical depigmented macules on the face resembling vitiligo. NLE is a rare condition affecting newborn infants of mothers who have connective tissue disease, with or without autoantibodies to extractable nuclear antigens Ro (...

journal_title：Clinical and experimental dermatology

authors： Jenkins RE,Kurwa AR,Atherton DJ,Black MM

更新日期：1994-09-01 00:00:00

abstract：:We present a case of paraneoplastic pemphigus associated with Castleman's disease. Our patient had stomatitis and vulvar erosions followed by a cutaneous polymorphous eruption. Investigations for neoplasia disclosed a Castleman's tumour suggesting the diagnosis of paraneoplastic pemphigus. The diagnosis was supported ...

journal_title：Clinical and experimental dermatology

authors： Caneppele S,Picart N,Bayle-Lebey P,Paul J,Irsutti M,Oksman F,Joly P,Bazex J

更新日期：2000-05-01 00:00:00

abstract：:A patient is reported who developed dysplastic naevi at an early age. He also suffered from a syndrome including Wilms' tumour, aniridia, mental retardation and diabetes mellitus in association with an interstitial deletion of the short arm of chromosome 11. It is suggested that genetic factors may be important in spo...

journal_title：Clinical and experimental dermatology

authors： McDonagh AJ,Wright AL,Messenger AG

更新日期：1990-01-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomata (MCL) is an autosomal dominant disorder characterized by the development of benign smooth muscle tumours (leiomyomas) in the skin and uterus of affected women, and in the skin of affected men. In rare cases, MCL has been associated with a predisposition to the rare type II pa...

journal_title：Clinical and experimental dermatology

authors： Chuang GS,Martinez-Mir A,Engler DE,Gmyrek RF,Zlotogorski A,Christiano AM

更新日期：2006-01-01 00:00:00

abstract：:Ten psoriatic patients were treated with an accelerated PUVA regimen. Nine patients cleared in an average of 13.7 treatments (range 4-24) after an average total UVA dose of 83 J/cm2 (range 18-186). One patient had to withdraw due to pruritus and burning and six others had burning problems. The high incidence of burnin...

journal_title：Clinical and experimental dermatology

authors： Green C,George S,Lakshmipathi T,Ferguson J

更新日期：1993-07-01 00:00:00

abstract：:Cutaneous drug eruptions have a variety of clinical features. Lichenoid drug eruptions are rare and may be difficult to diagnose. A case of a simvastatin-induced lichenoid eruption with skin and mucosal involvement is reported. ...

journal_title：Clinical and experimental dermatology

authors： Roger D,Rolle F,Labrousse F,Brosset A,Bonnetblanc JM

更新日期：1994-01-01 00:00:00

abstract：:Lower eyelid involvement occurs in 6% of patients with discoid lupus erythematosus (DLE). Eyelid lesions are rarely the initial manifestation of DLE. We describe a 25-year-old woman presenting with discoid lesions of the lower eyelids, staphylococcal blepharitis and Meibomian gland dysfunction, who later developed a d...

journal_title：Clinical and experimental dermatology

authors： Ena P,Pinna A,Carta F

更新日期：2006-01-01 00:00:00

abstract：:A 45-year-old man presented with a 7-year history of keratosis lichenoides chronica (KLC), a mucocutaneous lichenoid disorder of keratinization with no known aetiology, without significant systemic associations. Our patient also had type I diabetes mellitus, mild hypertension and lipid abnormalities. The diagnosis and...

journal_title：Clinical and experimental dermatology

authors： Wozniacka A,Schwartz RA,Omulecki A,Lesiak A,Sysa-Jedrzejowska A

更新日期：2006-01-01 00:00:00

abstract：:Studies in white populations have confirmed advanced age as a risk factor for cutaneous melanoma, but in nonwhite populations, its role is less clear. To clarify a possible association in our local population, comprising 94.9% Chinese, a retrospective epidemiological study of 20 years of data on cutaneous melanoma bet...

journal_title：Clinical and experimental dermatology

authors： Hui SK,Tang WY,Wong TW,Lau KH,Lee S,Chong LY,Lo KK

更新日期：2007-05-01 00:00:00

abstract：:Common unifying features of the subepidermal blistering diseases are the presence of tense blisters clinically and demonstration by immunofluorescence of linear deposition of immunoreactants along the dermoepidermal junction. Further characterization of subtype is possible by identification of the target antigen by im...

journal_title：Clinical and experimental dermatology

authors： Rao R,Bhogal B,Groves R

更新日期：2013-04-01 00:00:00

abstract：:Vitiligo usually begins in childhood with approximately half of the patients manifesting onset of disease prior to the age of 20 years. Treatment options in this age group are few and have disappointing response rates. This study was designed to evaluate the role of narrow-band UVB in the treatment of generalized viti...

journal_title：Clinical and experimental dermatology

authors： Kanwar AJ,Dogra S

更新日期：2005-07-01 00:00:00

abstract：:Dermatology services are largely outpatient based. Time for satisfactory patient communication is limited, with an average of around 15 min per new patient. The amount of new information that can be retained after verbal communication alone is limited during such consultations. One way to reinforce such information is...

journal_title：Clinical and experimental dermatology

authors： Tomkins CS,Braid JJ,Williams HC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Numerous studies have associated HS with obesity, and recently with metabolic syndrome (MetS). Both obesity and MetS are linked with metabolic changes. Thyroid hormones play a central role in metabolism and exert pleiotropic effects on adipogen...

journal_title：Clinical and experimental dermatology

authors： Miller IM,Vinding G,Sørensen HA,Rytgaard H,Mogensen UB,Ellervik C,Jemec GB

更新日期：2018-12-01 00:00:00

abstract：:Divided or kissing naevi are located on adjacent parts of the body that are separated during embryogenesis. Divided naevus of the penis (DNP) is exceedingly rare, with < 15 cases reported in the English language literature. Divided penile naevi affect the glans penis and inner foreskin, which are anatomical structures...

journal_title：Clinical and experimental dermatology

authors： Mendes CP,Samorano LP,Alessi SS,Nico MM

更新日期：2014-08-01 00:00:00

abstract：:We performed an immunohistochemical study with 11 antikeratin antibodies using the newly developed AMeX (acetone-methylbenzoate-xylene) tissue processing method. Specimens processed with this method showed almost as good preservation and morphological detail as routinely processed, formalin-fixed and paraffin-embedded...

journal_title：Clinical and experimental dermatology

authors： Ansai SI,Koseki S,Hozumi Y,Kondo S

更新日期：1994-11-01 00:00:00

abstract：:We report a 72-year-old man on haemodialysis who presented with multiple abscesses on his lower legs. Routine bacterial culture of abscess pus was reported as 'sterile' after 48 h, leading to the suspicion of a mycobacterial infection. Skin biopsy taken for mycobacterial microscopy and culture isolated a heavy growth ...

journal_title：Clinical and experimental dermatology

authors： Morris-Jones R,Fletcher C,Morris-Jones S,Brown T,Hilton RM,Hay R

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Emerging evidence indicates that plasma interleukin (IL)-17 levels may be associated with increased risk of psoriasis, but the individual published results are inconclusive. AIM:To evaluate IL-17 levels in patients with psoriasis using a meta-analysis of studies comparing IL-17 levels in controls and in pat...

journal_title：Clinical and experimental dermatology

authors： Zhou XY,Bao J,Huang B,Jin Y

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Atopic eczema (AE) is characterized by reduced skin hydration (SH) and impaired integrity of the skin. Proper emollient usage is an important facet of AE management and patients are encouraged to use emollients liberally. AIM:To evaluate whether the amount of emollient and skin cleanser used correlates with...

journal_title：Clinical and experimental dermatology

authors： Hon KL,Ching GK,Leung TF,Choi CY,Lee KK,Ng PC

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Therapeutics targeting tumour necrosis factor (TNF)-α are effective for psoriasis; however, in patients treated for other disorders, psoriasis may worsen and psoriasiform dermatitis (PsoD) may arise. T helper (Th) cytokines in psoriasis upregulate keratin (K)17, which modulates TNF-α transduction, leading to...

journal_title：Clinical and experimental dermatology

authors： Moy AP,Murali M,Kroshinsky D,Horn TD,Nazarian RM

更新日期：2018-01-01 00:00:00

abstract：:This prospective study was undertaken to determine whether the 2-mm punch biopsy technique yields specimens of sufficient size and quality to allow a reliable histological diagnosis to be made. A histopathological comparison was made between tissue obtained from a 2-mm punch biopsy and a standard ellipse biopsy taken ...

journal_title：Clinical and experimental dermatology

authors： Todd P,Garioch JJ,Humphreys S,Seywright M,Thomson J,du Vivier AW

更新日期：1996-01-01 00:00:00

abstract：:Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per da...

journal_title：Clinical and experimental dermatology

authors： Tan A,Tan HH,Lee CC,Ng SK

更新日期：2003-05-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma of the skin, usually occurring at sun-exposed sites in elderly people. Divergent differentiation in MCC, although rare, has been reported in previous case series. We describe two new cases of MCC with divergent differentiation. Patient 1 was a 96-y...

journal_title：Clinical and experimental dermatology

authors： Gaitskell K,Nassar S,Ibrahim H

更新日期：2020-04-01 00:00:00

abstract：:Telangiectatic leg veins (TLV) are experienced by millions of women and men. As they cause significant cosmetic embarrassment, many women seek effective treatment. Options include sclerotherapy and treatment with different lasers. We investigated the safety and efficacy of an 810-nm diode laser in the treatment of TLV...

journal_title：Clinical and experimental dermatology

authors： Varma S,Lanigan SW

更新日期：2000-07-01 00:00:00

abstract：:We report a case of the rare porokeratosis variant porokeratosis ptychotropica (PP). A circumferential perianal plaque and the characteristic histology of multiple cornoid lamellae with underlying dermal amyloid deposition were seen. Amyloid deposition was seen in the biopsied intertriginous area of the plaque only, w...

journal_title：Clinical and experimental dermatology

authors： Tallon B,Blumental G,Bhawan J

更新日期：2009-12-01 00:00:00

abstract：:Small tufts of chest hair were epilated at different rates and the roots classified as to growth phase, presence or absence of root sheaths and whether the shafts were fractured. With respect to anagen roots, a slow epilation gives bare roots whereas an increase in the rate of epilation increases the proportion of ens...

journal_title：Clinical and experimental dermatology

authors： Chapman DM

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Port-wine stains (PWS) are congenital capillary malformations that persist throughout life. Laser therapy is a common treatment for PWS, and pulsed-dye laser is the current treatment of choice. AIM:To compare the clinical results on untreated PWS of two dye lasers with different wavelengths and pulse durati...

journal_title：Clinical and experimental dermatology

authors： Frohm Nilsson M,Passian S,Wiegleb Edstrom D

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The hyperactive melanocytes present in melasma skin are confined to the epidermis, but epidermal ablation to treat melasma pigmentation may lead to disease recurrence and aggravation. Melanocyte function is regulated by interactions between melanocytes and neighbouring cells such as keratinocytes and fibrobl...

journal_title：Clinical and experimental dermatology

authors： Byun JW,Park IS,Choi GS,Shin J

更新日期：2016-08-01 00:00:00

abstract：:A 78-year-old Caucasian woman developed Sweet's syndrome which progressed over 3 weeks to pyoderma gangrenosum and subcorneal pustule formation. In spite of treatment the patient died and post-mortem examination revealed cryptogenic cirrhosis which could have explained the spectrum of neutrophilic skin disease observe...

journal_title：Clinical and experimental dermatology

authors： Davies MG,Hastings A

更新日期：1991-07-01 00:00:00