Abstract:
:Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy the aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition that serum androgen levels may be elevated in this condition, and may be causative. We studied a cohort of 125 pregnant women presenting with a variety of pregnancy dermatoses of whom 12 had PF. These women were compared with 138 pregnant control subjects without a pregnancy dermatosis to determine whether serum androgens were elevated. There was no significant elevation of serum androgens in the 12 cases of PF. There was an overall preponderance of male infants among the PF cases and birthweight of the infants was found to be reduced compared with those of controls. However, the outcome of pregnancy in all cases was favourable implying that PF has no adverse effect on foetal wellbeing.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Vaughan Jones SA,Hern S,Black MMdoi
10.1046/j.1365-2230.1999.00510.xkeywords:
subject
Has Abstractpub_date
1999-09-01 00:00:00pages
392-5issue
5eissn
0307-6938issn
1365-2230pii
ced510journal_volume
24pub_type
杂志文章abstract:BACKGROUND:This is the first study investigating scabies treatment since 1992 to involve examination of patients with microscopically confirmed scabies. AIM:To assess the efficacy of 1% lindane cream in treating microscopically confirmed scabies, and to determine the utility of dermoscopy-guided skin scraping with mic...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.12643
更新日期:2015-08-01 00:00:00
abstract::Dermatology services are largely outpatient based. Time for satisfactory patient communication is limited, with an average of around 15 min per new patient. The amount of new information that can be retained after verbal communication alone is limited during such consultations. One way to reinforce such information is...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2004.01437.x
更新日期:2004-01-01 00:00:00
abstract::Ten psoriatic patients were treated with an accelerated PUVA regimen. Nine patients cleared in an average of 13.7 treatments (range 4-24) after an average total UVA dose of 83 J/cm2 (range 18-186). One patient had to withdraw due to pruritus and burning and six others had burning problems. The high incidence of burnin...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.1993.tb02201.x
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:Psoriasis involves a multifaceted interplay of keratinocytes, blood vessels, immune system mediators and expressed genes. AIM:To determine whether genetic polymorphisms in the angiopoietin-1 (ANGPT1), angiopoietin-2 (ANGPT2) and caspase-5 (CASP5) genes are associated with an increased risk of developing pso...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.12550
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Momordica charantia (MC; bitter gourd) is a traditional herb commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. It is also used for the rapid healing of wounds. AIM:To observe the topical effect of MC extract on the wound-healing process in rats with diabetes induce...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2008.03117.x
更新日期:2009-10-01 00:00:00
abstract::Three antituberculous drug regimens have been employed to study the therapeutic response in 90 patients with any one of the commonly encountered paucibacillary forms of skin tuberculosis, namely lupus vulgaris, tuberculosis verrucosa cutis and scrofuloderma. The first two regimens contained rifampicin, isoniazid and e...
journal_title:Clinical and experimental dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2230.1991.tb00317.x
更新日期:1991-03-01 00:00:00
abstract::The incidence of nonmelanoma skin cancer is significantly increased in recipients of solid-organ transplants. Photodynamic therapy (PDT) is a well-documented treatment option for superficial and selected nodular basal cell carcinomas (BCCs) in immunocompetent patients, but there are few reports describing PDT of BCCs ...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2011.04248.x
更新日期:2012-06-01 00:00:00
abstract::Erosive pustular dermatosis (EPD) of the leg is an unusual form of amicrobial pustulosis, which typically affects elderly patients with chronic venous insufficiency. We report a patient who presented with painful erythema, crusted erosions and pustules on her right lower leg. Histology showed a dermal infiltration mad...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.12512
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Corticosteroids, especially prednisolone or prednisone, are the most commonly used drugs for the treatment of bullous pemphigoid (BP). However, the appropriate initial effective prednisolone dose has not been established. Recently, a highly sensitive and specific ELISA for detection of autoantibodies to the ...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2010.04013.x
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Topical tacrolimus has shown remarkable clinical efficacy in treating many dermatoses. Combining ultraviolet (UV) B and tacrolimus is an intriguing therapeutic regimen, especially for treatment of vitiligo, for which combination therapy may show greater clinical efficacy than topical tacrolimus alone. The ph...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2009.03311.x
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that concomitant administration of food may enhance the bioavailability of oral retinoids. AIM:To assess the influence of food on the pharmacokinetics (PK) of alitretinoin after a single oral dose. METHODS:This was a single-dose, open-label, randomized, crossover study, which en...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2230.2011.04033.x
更新日期:2011-04-01 00:00:00
abstract::Angiogenesis plays an important role in progression of various tumours including malignant melanoma. It is possible that the immunostaining of angiogenic markers could differentiate benign and malignant melanocytic lesions or that the immunostaining pattern with angiogenic markers could vary with tumour thickness and ...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-2230.2002.00976.x
更新日期:2002-03-01 00:00:00
abstract::Evidence has suggested that vascular endothelial growth factor (VEGF), a crucial growth factor in regulating endothelial progenitor cells (EPCs), plays a central role in keloid formation. However, the levels of circulating EPCs in patients with keloid have not yet been explored. The aim of this study was to determine ...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.12695
更新日期:2016-03-01 00:00:00
abstract::It is a common experience that many Spitz naevi deviate from the idealized or stereotypical representation found in the literature, often causing considerable difficulties in distinguishing them from melanoma. The diagnostic term 'atypical Spitz naevus' is used to describe lesions that deviate from the typical appeara...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2007.02639.x
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Numerous studies have associated HS with obesity, and recently with metabolic syndrome (MetS). Both obesity and MetS are linked with metabolic changes. Thyroid hormones play a central role in metabolism and exert pleiotropic effects on adipogen...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.13606
更新日期:2018-12-01 00:00:00
abstract::A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.1989.tb01993.x
更新日期:1989-07-01 00:00:00
abstract::The effect of dietary supplementation with a combination of n-3 (marine oil) and n-6 (evening primrose oil) essential fatty acids in the treatment of chronic stable plaque psoriasis was observed. Thirty-seven patients in a double-blind parallel trial were studied. There was no significant improvement in clinical sever...
journal_title:Clinical and experimental dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2230.1994.tb01139.x
更新日期:1994-03-01 00:00:00
abstract::Idiopathic solar urticaria (SU) is a rare, debilitating photodermatosis, which may be difficult to treat. First-line treatment with antihistamines is effective in mild cases, but remission after phototherapeutic induction of tolerance is often short-lived. Other treatment options include plasma exchange, photopheresis...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2009.03374.x
更新日期:2009-12-01 00:00:00
abstract::Azathioprine is used in a variety of dermatological conditions. However, because of its side-effect profile, azathioprine is limited for use in patients with severe disease. An unpredictable, rare and potentially fatal side-effect of azathioprine is the development of a hypersensitivity reaction, often consisting of f...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2230.1995.tb01343.x
更新日期:1995-07-01 00:00:00
abstract::A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...
journal_title:Clinical and experimental dermatology
pub_type: 信件
doi:10.1111/j.1365-2230.2009.03543.x
更新日期:2009-10-01 00:00:00
abstract::A group of 23 patients with partial atrophic change of the tongue was examined for candidiasis. All of them reported pain in the tongue on eating hot or spicy food. The intensity of the tongue pain was evaluated before and after treatment using a visual analogue scale. Of the 23 patients, 10 (43.5%) had predisposing f...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2007.02383.x
更新日期:2007-07-01 00:00:00
abstract::Porphyria cutanea tarda (PCT) is believed to be associated with reduced hepatic uroporphyrinogen decarboxylase activity and risk factors such as alcohol abuse and medication with oral contraceptives and certain other drugs. Recently it has been suggested that hepatitis C virus (HCV) infection may also be associated wi...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.1996.tb00095.x
更新日期:1996-07-01 00:00:00
abstract::Tumoral calcinosis is an uncommon ectopic calcification syndrome characterized clinically by the presence of irregular, painless, periarticular soft tissue calcifying masses, and pathologically by fibrous-walled cystic spaces containing structureless calcific debris and associated with a variable inflammatory reaction...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Acquired reactive perforating collagenosis (ARPC) is an uncommon dermatosis characterized by transepidermal elimination of altered collagen. It is commonly seen in patients with diabetes mellitus and/or chronic renal insufficiency. Rarely, it has been reported in association with malignancy and other conditions. We re...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2009.03211.x
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:We conducted a re-audit of the surgical practice of UK dermatologists for the treatment of nonmelanoma skin cancer and examined changes with reference to our previous audit in 2014. The audit was supplemented by a detailed assessment of completeness of the histopathology reports for each tumour. METHODS:UK ...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.14034
更新日期:2020-01-01 00:00:00
abstract::We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with pr...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2009.03722.x
更新日期:2009-12-01 00:00:00
abstract::Japan is currently experiencing many outbreaks of scabies, occurring mainly in long-term care facilities. Scabies burrows, the only pathognomonic lesion for scabies, often occur on the creases of the palms, and are followed by a pattern of scale reminiscent of the 'wake' left on the surface of water by a moving bird o...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-2230.2008.03010.x
更新日期:2009-08-01 00:00:00
abstract::It is only in the past 10 years that the allergenic potential of topical corticosteroids has been fully realized. This has an important impact on the management of patients with chronic eczematous eruptions. Nonhalogenated topical steroids are more frequent sensitizers than halogenated molecules. Tixocortol pivalate a...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2230.2000.00637.x
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Lentigo maligna (LM) and lentigo maligna melanoma (LMM) can be difficult to manage surgically. Predetermined margins can be inadequate because of subclinical spread, or can affect function when margins are adjacent to the eye or mouth. AIM:To describe our 5-year experience in Nottingham of using the staged ...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1111/ced.12363
更新日期:2014-07-01 00:00:00
abstract::A retrospective study was made of the incidence of cutaneous melanoma among the population of the district of Rijeka (Croatia) during the period 1977-96. A total of 397 patients with cutaneous melanoma was documented during this period. Over the 20-year period the incidence of the tumour increased, the mean annual rat...
journal_title:Clinical and experimental dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-2230.2000.00579.x
更新日期:2000-01-01 00:00:00