Topical tacrolimus has a limited direct effect on ultraviolet B-irradiated keratinocytes: implications for its photocarcinogenic potential.

abstract：BACKGROUND:Recently, a new population of IL-17-producing CD4 T helper (Th) cells, named Th17, was identified and shown to be involved in various inflammatory and autoimmune diseases, including psoriasis. AIM:To determine the frequency of Th17 cells and related cytokines in peripheral blood of patients with psoriasis, ...

journal_title：Clinical and experimental dermatology

authors： Chhabra S,Narang T,Joshi N,Goel S,Sawatkar G,Saikia B,Dogra S,Bansal F,Minz R

更新日期：2016-10-01 00:00:00

abstract：:We present the case of a 68-year-old woman who developed a painful subcutaneous tumour in the sacral region. Histological examinations revealed a characteristic zonal pattern with a central zone of liquefactive necrosis, surrounded by proliferated atypical fibroblasts and prominent vessels, indicating ischaemic fascii...

journal_title：Clinical and experimental dermatology

authors： Kaneko T,Rokunohe D,Takiyoshi N,Minakawa S,Nakano H,Sawamura D

更新日期：2016-07-01 00:00:00

abstract：:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica of...

journal_title：Clinical and experimental dermatology

authors： Owen CM,Murphy H,Yates VM

更新日期：2001-03-01 00:00:00

abstract：:We report a case of cutaneous alternariosis in an immunocompetent 85-year-old man. Identification of the causative organism in this patient was achieved by 18S rRNA sequencing. A 6-month course of itraconazole led to a good clinical response. ...

journal_title：Clinical and experimental dermatology

authors： Williams C,Layton AM,Kerr K,Kibbler C,Barton RC

更新日期：2008-07-01 00:00:00

abstract：:A 59-year-old woman with a single cuff-like plaque, consisting of multiple skin-coloured to bluish cysts and comedones on her right forearm is reported. The solitary lesion resembled, morphologically and histologically, the Favre-Racouchot syndrome. The above condition is another case of the previously described actin...

journal_title：Clinical and experimental dermatology

authors： John SM,Hamm H

更新日期：1993-05-01 00:00:00

abstract：:Longitudinal splitting of the nails can occur as a result of any growth arising in the nail matrix. We present a case of a 50-year-old woman who presented with an 18-month history of longitudinal splitting of the nail on her right little finger, along with pain in the proximal nail fold region, which was extremely ten...

journal_title：Clinical and experimental dermatology

authors： Jha AK,Sinha R,Kumar A,Bhadani P,Kumar S

更新日期：2016-10-01 00:00:00

abstract：:Glyceryl trinitrate (nitroglycerin) has been in use for relief of angina for over a hundred years, but allergic reactions to it or to other organic nitrates rarely feature in the medical literature. Most of the case reports describe reactions to transdermally applied nitroglycerin. We report a case of a localized alle...

journal_title：Clinical and experimental dermatology

authors： Aquilina S,Felice H,Boffa MJ

更新日期：2002-11-01 00:00:00

abstract：:We present a 23-year-old woman with a diagnosis of keratolytic winter erythema (erythrokeratolysis hiemalis), who developed facial lesions following a traumatic experience. This rare genodermatosis usually affects the palms and soles, and appears as mild erythema and annular scaling. The limbs and trunk can rarely be ...

journal_title：Clinical and experimental dermatology

authors： Degiovanni CV,Farrant PB,Howell S,Hull PR,Woollons A

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:We conducted a re-audit of the surgical practice of UK dermatologists for the treatment of nonmelanoma skin cancer and examined changes with reference to our previous audit in 2014. The audit was supplemented by a detailed assessment of completeness of the histopathology reports for each tumour. METHODS:UK ...

journal_title：Clinical and experimental dermatology

authors： Keith DJ,Bray AP,Brain A,Mohd Mustapa MF,Barrett HE,Lane S,Emmerich M,Jakes A,Barrett PD,de Berker DAR

更新日期：2020-01-01 00:00:00

abstract：:Dermatomyositis has a significant clinical component of pruritus that has not yet been studied. Pruritus can significantly affect the life of patients. The aim of the present work was to study the degree of pruritus experienced by patients. A four-question survey was sent to patients with documented dermatomyositis. T...

journal_title：Clinical and experimental dermatology

authors： Shirani Z,Kucenic MJ,Carroll CL,Fleischer AB Jr,Feldman SR,Yosipovitch G,Jorizzo JL

更新日期：2004-05-01 00:00:00

abstract：:We report the case of a 30-year-old patient who developed scombrotoxic fish poisoning after eating cooked fresh tuna. Symptoms included a bright red rash, tightness of the chest, palpitations, anxiety, mild headache and dizziness, all of which resolved spontaneously within 2-3 h. Such poisoning results from the consum...

journal_title：Clinical and experimental dermatology

authors： Sabroe RA,Kobza Black A

更新日期：1998-11-01 00:00:00

abstract：:Urticarial vasculitis (UV) is a mainly leucocytoclastic vasculitis with urticarial plaques. Treating these patients is challenging as the available treatments have poor efficacy. Oral corticosteroids are considered the first-line treatment, but H1 antihistamines, dapsone, colchicine, antimalarials, ciclosporin and ant...

journal_title：Clinical and experimental dermatology

authors： Fueyo-Casado A,Campos-Muñoz L,González-Guerra E,Pedraz-Muñoz J,Cortés-Toro JA,López-Bran E

更新日期：2017-06-01 00:00:00

abstract：:Intravenous (IV) calcium is usually given to temporarily treat the effects of hyperkalaemia on muscle and heart. When extravasation of a calcium gluconate infusion occurs, there may be rapid and marked swelling and erythema, with signs of soft-tissue necrosis or infection, and ensuing extensive local calcification, ca...

journal_title：Clinical and experimental dermatology

authors： Celbek G,Gungor A,Albayrak H,Kir S,Guvenc SC,Aydin Y

更新日期：2013-03-01 00:00:00

abstract：:We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with pr...

journal_title：Clinical and experimental dermatology

authors： Perez A,Clements SE,Benton E,Robson A,Bhogal B,Stefanato CM,McGibbon D

更新日期：2009-12-01 00:00:00

abstract：:Three patients with subungual exostoses, two involving the great toe and one the fourth toe, are presented. Local excision was performed, and the specimens were processed for light and electron microscopy. Light-microscopic study revealed that the tumours consisted of a proliferative fibrocartilaginous cap that merged...

journal_title：Clinical and experimental dermatology

authors： Kato H,Nakagawa K,Tsuji T,Hamada T

更新日期：1990-11-01 00:00:00

abstract：:Myiasis is a condition resulting from the invasion of tissues or organs of man or animals by the larvae of dipterous flies. The distribution of myiasis is worldwide, with more cases being reported from tropical, subtropical, and warm temperate areas. The various forms of myiasis may be classified from an entomological...

journal_title：Clinical and experimental dermatology

authors： Delir S,Handjani F,Emad M,Ardehali S

更新日期：1999-07-01 00:00:00

abstract：:Down's syndrome (DS) is associated with rare dermatological disorders and increased frequency of some common dermatoses. Owing to advances in medical care and changes in attitude, the median age of death in this population has increased to 49 years, and the life expectancy of a 1-year-old person with DS today is more ...

journal_title：Clinical and experimental dermatology

authors： Madan V,Williams J,Lear JT

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Emerging evidence indicates that plasma interleukin (IL)-17 levels may be associated with increased risk of psoriasis, but the individual published results are inconclusive. AIM:To evaluate IL-17 levels in patients with psoriasis using a meta-analysis of studies comparing IL-17 levels in controls and in pat...

journal_title：Clinical and experimental dermatology

authors： Zhou XY,Bao J,Huang B,Jin Y

更新日期：2017-03-01 00:00:00

abstract：:Evidence has suggested that vascular endothelial growth factor (VEGF), a crucial growth factor in regulating endothelial progenitor cells (EPCs), plays a central role in keloid formation. However, the levels of circulating EPCs in patients with keloid have not yet been explored. The aim of this study was to determine ...

journal_title：Clinical and experimental dermatology

authors： Zhang GY,Wu LC,Liao T,Chen G,Chen YH,Meng XC,Wang AY,Chen SY,Lin K,Lin DM,Gao WY,Li QF

更新日期：2016-03-01 00:00:00

abstract：:A patient is reported who developed dysplastic naevi at an early age. He also suffered from a syndrome including Wilms' tumour, aniridia, mental retardation and diabetes mellitus in association with an interstitial deletion of the short arm of chromosome 11. It is suggested that genetic factors may be important in spo...

journal_title：Clinical and experimental dermatology

authors： McDonagh AJ,Wright AL,Messenger AG

更新日期：1990-01-01 00:00:00

abstract：:Many types of histiocytoses have been described. We present a case of a 56-year-old woman who presented with multiple nodules on the hands. On histological examination of an excision biopsy, a mainly dermal lesion was seen, with scattered mononuclear inflammatory cells and occasional multinucleated cells in the backgr...

journal_title：Clinical and experimental dermatology

authors： Patel AN,Cohen SN,Leach IH,Scharrer K

更新日期：2012-04-01 00:00:00

abstract：:A 68-year-old Caucasian male presented with a 5-week history of a widespread pruritic papular eruption. Histology from a papule on the left shoulder showed a dense dermal infiltrate of large mononuclear cells which were positive for leucocyte common antigen, KP1 and PGM1, with an MIB-1 proliferating fraction of 40%, d...

journal_title：Clinical and experimental dermatology

authors： Millard TP,Aitchison R,Wilkinson JD

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Cutis marmorata telangiectatica congenita (CMTC) is a congenital vascular anomaly of unknown aetiology. About 300 cases have been reported in the literature. The rate of associated anomalies varies between 20% and 70%. METHODS:We report a series of 27 children with CMTC, 18 of whom were followed-up prospect...

journal_title：Clinical and experimental dermatology

authors： Kienast AK,Hoeger PH

更新日期：2009-04-01 00:00:00

abstract：:Angiolymphoid hyperplasia with eosinophilia (AHE) is a benign reactive vascular lesion characterized by a proliferation of small to medium sized vascular structures lined by epithelioid endothelial cells. We report a 75-year-old woman with a 1-month history of a painful ulcer on the tongue. Histopathological findings ...

journal_title：Clinical and experimental dermatology

authors： Garrido-Ríos AA,Sanz-Muñoz C,Torrero-Antón MV,Martínez-García G,Miranda-Romero A

更新日期：2009-12-01 00:00:00

abstract：:Teledermatology has been the focus of much interest in recent years. Potential uses include a simple supporting role for primary care, more accurate triage of dermatology patients or an 'advice only' service reducing the need for dermatology patients to attend outpatient clinics. With the current under-provision of de...

journal_title：Clinical and experimental dermatology

authors： Mallett RB

更新日期：2003-07-01 00:00:00

abstract：:Dystrophic epidermolysis bullosa (DEB) is caused by mutations in the COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils. The characteristic genetic lesion in dominant DEB (DDEB) is a glycine substitution in the collagenous domain of the protein. In this study, we identified a Chinese fami...

journal_title：Clinical and experimental dermatology

authors： Zhang XJ,Song YX,Zhang XQ,Yang S,Li M,Li CR,Yang CJ,Yang J

更新日期：2003-07-01 00:00:00

abstract：:Human Herpesvirus 8 (HHV-8) has been implicated in the pathogenesis of Kaposi's sarcoma (KS). In this paper we attempted to confirm the connection between dialysis, HHV-8, and KS by examining the case of an elderly haemodialysis nonimmunosuppressed male patient with end-stage renal disease, who developed KS. By using ...

journal_title：Clinical and experimental dermatology

authors： Metaxa-Mariatou V,Chiras T,Loli A,Gazouli M,Vallis D,Nasioulas G

更新日期：2004-03-01 00:00:00

abstract：:Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder that causes defects in the DNA repair system. It is characterized by a marked sensitivity to sunlight, and sufferers develop serious sunburns with onset of poikilodermia in the light-exposed skin. Squamous cell carcinomas, basal cell carcinomas (BCCs) a...

journal_title：Clinical and experimental dermatology

authors： Roseeuw D

更新日期：2003-11-01 00:00:00

abstract：:Majocchi's granuloma, also known as nodular granulomatous perifolliculitis, is an uncommon fungal infection of the skin and subcutaneous tissue. It can occur in healthy and immunocompromised patients. The most common cause of Majocchi's granuloma is Trichophyton rubrum. We report a case of a Majocchi's granuloma cause...

journal_title：Clinical and experimental dermatology

authors： Saadat P,Kappel S,Young S,Abrishami M,Vadmal MS

更新日期：2008-07-01 00:00:00

abstract：:Four patients presenting with chronic pigmented purpuric dermatosis (CPPD) on the limbs were found to have granulomatous inflammation superimposed on the pathological changes of CPPD. Three of the four patients had hyperlipidaemia. Therefore, the granulomatous reaction observed could be associated with hyperlipidaemia...

journal_title：Clinical and experimental dermatology

authors： Lin WL,Kuo TT,Shih PY,Lin WC,Wong WR,Hong HS

更新日期：2007-09-01 00:00:00