Spiradenoma causing longitudinal splitting of the nail.

abstract：:Treatment of autoimmune blistering diseases consists of systemic glucocorticosteroids usually in combination with additional immunosuppressants such as azathioprine and mycophenolate mofetil or immunomodulators such as dapsone, antibiotics, intravenous immunoglobulins, and immunoadsorption. In some patients, these tre...

journal_title：Clinical and experimental dermatology

authors： Schmidt E,Hunzelmann N,Zillikens D,Bröcker EB,Goebeler M

更新日期：2006-07-01 00:00:00

abstract：:Ninety-six patients with a clinical and parasitological diagnosis of cutaneous leishmaniasis were recruited to a comparative randomized clinical trial evaluating the efficacy of topical paromomycin vs. weekly intralesional injections of meglumine antimoniate. The patients were randomly divided into two treatment group...

journal_title：Clinical and experimental dermatology

authors： Faghihi G,Tavakoli-kia R

更新日期：2003-01-01 00:00:00

abstract：:Bullous pemphigoid (BP) is an autoimmune disease mediated by autoantibodies against hemidesmosome components. This study used PCR-sequence-specific primers to genotype polymorphisms in HLA-DR and DQ in 25 BP patients and 57 normal controls from northern China. We found lower frequencies of DRB1*08 (DR8) and DRB1*08/DQ...

journal_title：Clinical and experimental dermatology

authors： Gao XH,Winsey S,Li G,Barnardo M,Zhu XJ,Chen HD,Song F,Zhai N,Fuggle S,Wojnarowska F

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Cutis marmorata telangiectatica congenita (CMTC) is a congenital vascular anomaly of unknown aetiology. About 300 cases have been reported in the literature. The rate of associated anomalies varies between 20% and 70%. METHODS:We report a series of 27 children with CMTC, 18 of whom were followed-up prospect...

journal_title：Clinical and experimental dermatology

authors： Kienast AK,Hoeger PH

更新日期：2009-04-01 00:00:00

abstract：:We report the occurrence of severe symptomatic bronchoconstriction in an atopic asthmatic subject following the application of coal tar bandages. Investigations showed that this was likely to have been caused by inhalation of coal tar vapour. We suggest that coal tar preparations should be used with caution in asthmat...

journal_title：Clinical and experimental dermatology

authors： Ibbotson SH,Stenton SC,Simpson NB

更新日期：1995-01-01 00:00:00

abstract：:High-dose intravenous immunoglobulin (hdIVIg) is being used increasingly for dermatological indications. Its mode of action is via a number of proposed mechanisms and it is not associated with the many side-effects of steroids and other immunosuppressive agents. The evidence for using hdIVIg in the treatment of autoim...

journal_title：Clinical and experimental dermatology

authors： Jolles S

更新日期：2001-03-01 00:00:00

abstract：:IgA pemphigus is rare but may be underdiagnosed. We describe two cases, a 50-year-old female with a pustular eruption resembling subcorneal pustular dermatosis and a 55-year-old male with a pruritic vesiculopustular eruption simulating dermatitis herpetiformis. They illustrate the clinical heterogeneity of IgA pemphig...

journal_title：Clinical and experimental dermatology

authors： Harman KE,Holmes G,Bhogal BS,McFadden J,Black MM

更新日期：1999-11-01 00:00:00

abstract：:Alopecia areata (AA) is a recurrent, immune-mediated, hair-loss disorder. It is associated with other autoimmune disorders that carry a high risk of cardiovascular disease (CVD). However, there is a lack of reports on the association of cardiovascular comorbidities and AA. Cardiac troponin I is a biomarker of myocardi...

journal_title：Clinical and experimental dermatology

authors： El-Sayed Mahmoud Marie R,El-Sayed GAK,Attia FM,Gomaa AHA

更新日期：2021-01-01 00:00:00

abstract：:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. We report a case in which identical T-cell clones were identified in both patch and tumour stage lesions and in which the tumorous deposits, containing CD30-positive cells, regressed spontaneously. We discuss the differential diagnosis of the tumorou...

journal_title：Clinical and experimental dermatology

authors： Woodrow SL,Basarab T,Russell Jones R

更新日期：1996-09-01 00:00:00

abstract：:Dystrophic epidermolysis bullosa (DEB) is caused by mutations in the COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils. The characteristic genetic lesion in dominant DEB (DDEB) is a glycine substitution in the collagenous domain of the protein. In this study, we identified a Chinese fami...

journal_title：Clinical and experimental dermatology

authors： Zhang XJ,Song YX,Zhang XQ,Yang S,Li M,Li CR,Yang CJ,Yang J

更新日期：2003-07-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomata (MCL) is an autosomal dominant disorder characterized by the development of benign smooth muscle tumours (leiomyomas) in the skin and uterus of affected women, and in the skin of affected men. In rare cases, MCL has been associated with a predisposition to the rare type II pa...

journal_title：Clinical and experimental dermatology

authors： Chuang GS,Martinez-Mir A,Engler DE,Gmyrek RF,Zlotogorski A,Christiano AM

更新日期：2006-01-01 00:00:00

abstract：:Severe cases of psoriasis and psoriasis arthritis require systemic treatment. Although a number of established drugs are in clinical use, there is a need for new compounds with an improved risk-benefit ratio with a major emphasis on long-term safety. Furthermore, patients with moderate psoriasis ask for systemic drugs...

journal_title：Clinical and experimental dermatology

authors： Mrowietz U

更新日期：2001-06-01 00:00:00

abstract：:We report the case of a 24-year-old woman with an 8-month history of deep pelvic pain and postcoital bleeding. Examination revealed desquamation of the vaginal epithelium with tender fissured plaques in the vagina, initially thought to be vaginal intraepithelial neoplasia. Histology showed squamous mucosa with supraba...

journal_title：Clinical and experimental dermatology

authors： Kentley J,Cerio R,Khorshid M,Gibbon K

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Data on the dermoscopic features of fungal melanonychia are limited. AIM:To identify the dermoscopic features of fungal melanonychia. METHODS:We reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past y...

journal_title：Clinical and experimental dermatology

authors： Kilinc Karaarslan I,Acar A,Aytimur D,Akalin T,Ozdemir F

更新日期：2015-04-01 00:00:00

abstract：:Pachydermodactyly describes a rare condition of localized fibromatosis, usually symmetrically affecting the interphalangeal joints of both hands. We describe a case of a new subtype of pachydermodactyly in a 14-year-old boy, which we term 'unilateral pachydermodactyly transgrediens'. This atypical pattern is caused by...

journal_title：Clinical and experimental dermatology

authors： Nicolay JP,Faulhaber J,Kutzner H,Schneider SW

更新日期：2015-08-01 00:00:00

abstract：:Angiogenesis plays an important role in progression of various tumours including malignant melanoma. It is possible that the immunostaining of angiogenic markers could differentiate benign and malignant melanocytic lesions or that the immunostaining pattern with angiogenic markers could vary with tumour thickness and ...

journal_title：Clinical and experimental dermatology

authors： Dawn G,MacKie RM

更新日期：2002-03-01 00:00:00

abstract：:We wish to report the progress of a patient with pyoderma faciale and Crohn's disease. The patient is interesting in that on two occasions the relapse in her skin condition coincided with the introduction of non-steroidal anti-inflammatory drugs. Therapy with isotretinoin was effective and well tolerated. ...

journal_title：Clinical and experimental dermatology

authors： McHenry PM,Hudson M,Smart LM,Rennie JA,Mowat NA,White MI

更新日期：1992-11-01 00:00:00

abstract：:Chromonychia induced by antineoplastic agents has been known for several years. The most frequent of these is melanonychia, either diffuse or in tranverse or longitudinal bands, that may co-exist with diffuse pigmentation of the skin. Although any cytostatic agent may be involved in melanonychia, this condition appear...

journal_title：Clinical and experimental dermatology

authors： Unamuno P,Fernández-López E,Santos C

更新日期：1992-07-01 00:00:00

abstract：:Amyopathic dermatomyositis (ADM) is characterized clinically by typical skin lesions with hypomyopathy or no muscular involvement. ADM has been recently reported to be complicated by rapidly progressive interstitial lung disease (ILD), especially in patients with positive antibodies against melanoma differentiation-as...

journal_title：Clinical and experimental dermatology

authors： Molina-Ruiz AM,Romero F,Carrasco L,Feltes F,Haro R,Requena L

更新日期：2015-12-01 00:00:00

abstract：:Graham Little-Piccardi-Lassueur syndrome (GLPLS) is a rare lichenoid dermatosis defined by scarring alopecia, loss of pubic and axillary hairs and progressive development of horny follicular papules variously located. Topical or systemic corticosteroids, retinoids or PUVA therapy are the treatments usually proposed an...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Paro Vidolin A,Piemonte P,Carboni I,Chimenti S

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The dorsum of the hand is a common site for squamous cell carcinoma, and excision with appropriate margins often results in surgical defects that cannot be repaired by primary side-to-side closure. AIM:To assess healing time, complications and resulting scars when surgical wounds on the dorsum of the hand w...

journal_title：Clinical and experimental dermatology

authors： Lateo SA,Langtry JA

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Haemangioma of infancy (HOI) is the most frequently occurring benign tumour of infancy. A good, reliable and objective scoring system for haemangioma activity is not yet available. AIM:We have developed a simple system called the Haemangioma Activity Score (HAS) for scoring the (disease) proliferative activ...

journal_title：Clinical and experimental dermatology

authors： Janmohamed SR,de Waard-van der Spek FB,Madern GC,de Laat PC,Hop WC,Oranje AP

更新日期：2011-10-01 00:00:00

abstract：:Asymmetrical periflexural exanthem is a rare clinical condition, seen almost exclusively in children. Very few adult cases have been reported in the literature. We report a case of this rare eruption in an adult man showing characteristic clinical and histological features. Interestingly, this patient also exhibited a...

journal_title：Clinical and experimental dermatology

authors： Dar NR,Raza N

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Erythromelalgia is a rare disorder characterized by the clinical syndrome of burning pain, warmth and redness of the limbs. Neurological abnormalities (both large- and small-fibre neuropathy) are common. There have been few published reports on the sensory status of patients with erythromelalgia. AIM:To inv...

journal_title：Clinical and experimental dermatology

authors： Genebriera J,Michaels JD,Sandroni P,Davis MD

更新日期：2012-06-01 00:00:00

abstract：:We report a man with a 3-year-history of a striking eruption of small, 2-3 mm diameter keratotic, crateriform papules distributed symmetrically over the lower limbs. Morphologically the individual papules closely resembled those described in acrokeratoelastoidosis (AK) of Costa and in focal acral hyperkeratosis of Dow...

journal_title：Clinical and experimental dermatology

authors： Helbling I,Tucker SC,Chalmers RJ

更新日期：2001-05-01 00:00:00

abstract：:Down's syndrome (DS) is associated with rare dermatological disorders and increased frequency of some common dermatoses. Owing to advances in medical care and changes in attitude, the median age of death in this population has increased to 49 years, and the life expectancy of a 1-year-old person with DS today is more ...

journal_title：Clinical and experimental dermatology

authors： Madan V,Williams J,Lear JT

更新日期：2006-09-01 00:00:00

abstract：:Netherton syndrome (NS) is a rare and severe autosomal recessive ichthyosis. We report the case of a patient with NS treated successfully with narrowband ultraviolet B (NB-UVB) phototherapy after failure of low-dose oral isotretinoin. A 16-year-old girl born to consanguineous parents presented with severe ichthyosis. ...

journal_title：Clinical and experimental dermatology

authors： Maatouk I,Moutran R,Tomb R

更新日期：2012-06-01 00:00:00

abstract：:Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intrig...

journal_title：Clinical and experimental dermatology

authors： Sethuraman G,Srinivas CR,D'Souza M,Thappa DM,Smiles L

更新日期：2002-09-01 00:00:00

abstract：:The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site (face, dorsal right forearm and han...

journal_title：Clinical and experimental dermatology

authors： Green C,Orchard G,Cerio R,Hawk JL

更新日期：1998-07-01 00:00:00

abstract：:The two photodermatoses, polymorphic light eruption (PLE) and chronic actinic dermatitis (CAD), are characterized by lymphocyte-rich inflammatory infiltrates, the pathogeneses of which are not fully understood. We have therefore studied suction blister fluid (SBF) samples from patients with these conditions before and...

journal_title：Clinical and experimental dermatology

authors： Norris P,Bacon K,Bird C,Hawk J,Camp R

更新日期：1999-07-01 00:00:00