Acantholytic dermatosis of the vagina: the diagnostic challenge of acantholytic disease in the genital region.

Abstract:

:We report the case of a 24-year-old woman with an 8-month history of deep pelvic pain and postcoital bleeding. Examination revealed desquamation of the vaginal epithelium with tender fissured plaques in the vagina, initially thought to be vaginal intraepithelial neoplasia. Histology showed squamous mucosa with suprabasal acantholysis and hyperkeratosis, and no evidence of viral infection, dysplasia or malignancy. These findings were consistent with acantholytic dermatosis (AD), a rare lesion that resembles Hailey-Hailey and Darier disease histopathologically, but can be distinguished on a clinical basis. Vulval cases of AD are well recognized, but to our knowledge, this is the first reported case involving the vaginal epithelium alone.

journal_name

Clin Exp Dermatol

authors

Kentley J,Cerio R,Khorshid M,Gibbon K

doi

10.1111/ced.13026

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

189-191

issue

2

eissn

0307-6938

issn

1365-2230

journal_volume

42

pub_type

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