Merkel cell carcinoma with divergent differentiation.

abstract：:The Langerhans cells in the lentigines of four patients with the Leopard syndrome contained large membrane bound accumulations of melanin granules. Giant melanosomes were only seen in two patients. The patients had no immune-based symptoms relating to their lentigines. The Leopard Syndrome, also known as multiple lent...

journal_title：Clinical and experimental dermatology

authors： Fryer PR,Pope FM

更新日期：1992-01-01 00:00:00

abstract：:Histology sections from 61 cases of squamous cell carcinoma (SCC) of the vulva presenting after 1988 were reviewed for evidence of associated epithelial abnormality. Of the 50 patients with epithelium adjacent to the tumour, 24 had histological evidence of lichen sclerosus (LS), 20 of severe vulvar intraepithelial neo...

journal_title：Clinical and experimental dermatology

authors： Zaki I,Dalziel KL,Solomonsz FA,Stevens A

更新日期：1996-09-01 00:00:00

abstract：:The literature reveals what little is known about nutritional factors and hair loss. What we do know emanates from studies in protein-energy malnutrition, starvation, and eating disorders. In otherwise healthy individuals, nutritional factors appear to play a role in subjects with persistent increased hair shedding. H...

journal_title：Clinical and experimental dermatology

authors： Rushton DH

更新日期：2002-07-01 00:00:00

abstract：:We describe a patient with intermittent unilateral hyperhidrosis localized to the left hand only. Histology confirmed the presence of an eccrine naevus. ...

journal_title：Clinical and experimental dermatology

authors： Parslew R,Lewis-Jones MS

更新日期：1997-09-01 00:00:00

abstract：:Clinicians have become increasingly aware of the important effects of psoriasis on patients' quality of life. As a result, several measures of the disabilities and handicaps associated with psoriasis have been developed. The Psoriasis Disability Index (PDI) has been shown to be sensitive to changes in the extent of le...

journal_title：Clinical and experimental dermatology

authors： Kent G,al-Abadie M

更新日期：1993-09-01 00:00:00

abstract：:A group of 23 patients with partial atrophic change of the tongue was examined for candidiasis. All of them reported pain in the tongue on eating hot or spicy food. The intensity of the tongue pain was evaluated before and after treatment using a visual analogue scale. Of the 23 patients, 10 (43.5%) had predisposing f...

journal_title：Clinical and experimental dermatology

authors： Terai H,Shimahara M

更新日期：2007-07-01 00:00:00

abstract：:Chromonychia induced by antineoplastic agents has been known for several years. The most frequent of these is melanonychia, either diffuse or in tranverse or longitudinal bands, that may co-exist with diffuse pigmentation of the skin. Although any cytostatic agent may be involved in melanonychia, this condition appear...

journal_title：Clinical and experimental dermatology

authors： Unamuno P,Fernández-López E,Santos C

更新日期：1992-07-01 00:00:00

abstract：:This article forms part of a series of annual updates that summarizes the evidence base for atopic eczema (AE). It provides a summary of key findings from 28 systematic reviews that were published or indexed during 2017, and focuses on the epidemiology, aetiology and risk factors of AE. AE is the largest single contri...

journal_title：Clinical and experimental dermatology

authors： Hale G,Davies E,Grindlay DJC,Rogers NK,Harman KE

更新日期：2019-12-01 00:00:00

abstract：:Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy the aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition th...

journal_title：Clinical and experimental dermatology

authors： Vaughan Jones SA,Hern S,Black MM

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Metallothioneins (MTs) are a group of proteins widely distributed in tissues regulating metal metabolism, scavenging free radicals, and taking part in immunological reactions. Knockout mice for MT genes I and II (MT(-/-)) exhibit reduced tolerance to ultraviolet B injury in vivo. Upregulation of MT proteins ...

journal_title：Clinical and experimental dermatology

authors： Ma C,Li LF,Zhang BX

更新日期：2007-07-01 00:00:00

abstract：:Klippel-Trenaunay (KT) syndrome is a vascular malformation characterized by a port-wine stain, varicose veins and hypertrophy of the affected limb. Ulceration is considered an uncommon complication of KT syndrome and occurrence of skin cancer has been previously reported only in one case. We observed a case of KT synd...

journal_title：Clinical and experimental dermatology

authors： De Simone C,Giampetruzzi AR,Guerriero C,De Masi M,Amerio P,Cina G

更新日期：2002-05-01 00:00:00

abstract：:Acne is a common and complex skin disease, with a very complex pathogenesis. Although in women the relationship between acne and insulin resistance is well known, in particular in women with PCOS, in males this relationship has been poorly investigated. In total, 20 subjects with an altered metabolic profile were cons...

journal_title：Clinical and experimental dermatology

authors： Fabbrocini G,Izzo R,Faggiano A,Del Prete M,Donnarumma M,Marasca C,Marciello F,Savastano R,Monfrecola G,Colao A

更新日期：2016-01-01 00:00:00

abstract：:Graham Little-Piccardi-Lassueur syndrome (GLPLS) is a rare lichenoid dermatosis defined by scarring alopecia, loss of pubic and axillary hairs and progressive development of horny follicular papules variously located. Topical or systemic corticosteroids, retinoids or PUVA therapy are the treatments usually proposed an...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Paro Vidolin A,Piemonte P,Carboni I,Chimenti S

更新日期：2001-09-01 00:00:00

abstract：:We report a case of toxic pustuloderma secondary to thalidomide in a patient with severe nodular prurigo. To our knowledge this is the first reported case. With the increasing use of thalidomide for a variety of dermatological conditions it is clearly important that this rare side-effect now be recognised. ...

journal_title：Clinical and experimental dermatology

authors： Darvay A,Basarab T,Russell-Jones R

更新日期：1997-11-01 00:00:00

abstract：:Myiasis is a condition resulting from the invasion of tissues or organs of man or animals by the larvae of dipterous flies. The distribution of myiasis is worldwide, with more cases being reported from tropical, subtropical, and warm temperate areas. The various forms of myiasis may be classified from an entomological...

journal_title：Clinical and experimental dermatology

authors： Delir S,Handjani F,Emad M,Ardehali S

更新日期：1999-07-01 00:00:00

abstract：:Although many antihistamines are now in clinical use, few studies directly compare their pharmacodynamic and sedative activities in humans in vivo. We designed a double-blind, placebo-controlled, crossover study to compare the inhibitory effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-in...

journal_title：Clinical and experimental dermatology

authors： Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2004-09-01 00:00:00

abstract：:Although Q-switched (QS) lasers are the mainstay of modern tattoo removal, paradoxical darkening of tattoo ink may occur. This darkening of tattoo ink is dependent on laser wavelength, pulse duration and fluence, with high-energy, nanosecond-pulsed lasers more prone to induce tattoo-ink darkening. Laser toning, consis...

journal_title：Clinical and experimental dermatology

authors： Chung WK,Yang JH,Lee DW,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2009-12-01 00:00:00

abstract：:Stewart-Bluefarb syndrome (SBS) is a subtype of pseudo-Kaposi sarcoma (PKS), which is associated with congenital arteriovenous malformation. It is a rare syndrome, characterized by cutaneous lesions with onset in the second decade of life. We report a case of SBS in a 33-year-old man presenting with a 15-year history ...

journal_title：Clinical and experimental dermatology

authors： Verma SB,Vasani R

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Topical tacrolimus has shown remarkable clinical efficacy in treating many dermatoses. Combining ultraviolet (UV) B and tacrolimus is an intriguing therapeutic regimen, especially for treatment of vitiligo, for which combination therapy may show greater clinical efficacy than topical tacrolimus alone. The ph...

journal_title：Clinical and experimental dermatology

authors： Lan CC,Yu HS,Huang SM,Wu CS,Kuo HY,Lee CH,Lin CS,Chen GS

更新日期：2010-03-01 00:00:00

abstract：:Pachydermodactyly describes a rare condition of localized fibromatosis, usually symmetrically affecting the interphalangeal joints of both hands. We describe a case of a new subtype of pachydermodactyly in a 14-year-old boy, which we term 'unilateral pachydermodactyly transgrediens'. This atypical pattern is caused by...

journal_title：Clinical and experimental dermatology

authors： Nicolay JP,Faulhaber J,Kutzner H,Schneider SW

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Haemangioma of infancy (HOI) is the most frequently occurring benign tumour of infancy. A good, reliable and objective scoring system for haemangioma activity is not yet available. AIM:We have developed a simple system called the Haemangioma Activity Score (HAS) for scoring the (disease) proliferative activ...

journal_title：Clinical and experimental dermatology

authors： Janmohamed SR,de Waard-van der Spek FB,Madern GC,de Laat PC,Hop WC,Oranje AP

更新日期：2011-10-01 00:00:00

abstract：:We report the case of a 24-year-old woman with an 8-month history of deep pelvic pain and postcoital bleeding. Examination revealed desquamation of the vaginal epithelium with tender fissured plaques in the vagina, initially thought to be vaginal intraepithelial neoplasia. Histology showed squamous mucosa with supraba...

journal_title：Clinical and experimental dermatology

authors： Kentley J,Cerio R,Khorshid M,Gibbon K

更新日期：2017-03-01 00:00:00

abstract：:We report the case of a 28-year-old homosexual man with advanced HIV disease (CDC classification group IV A) who developed erythrodermic psoriasis which responded to calcipotriol, a topical vitamin D analogue. We believe this to be the first reported case of HIV-related psoriasis responsive to this form of treatment. ...

journal_title：Clinical and experimental dermatology

authors： Gray JD,Bottomley W,Layton AM,Cotterill JA,Monteiro E

更新日期：1992-09-01 00:00:00

abstract：:A 78-year-old Caucasian woman developed Sweet's syndrome which progressed over 3 weeks to pyoderma gangrenosum and subcorneal pustule formation. In spite of treatment the patient died and post-mortem examination revealed cryptogenic cirrhosis which could have explained the spectrum of neutrophilic skin disease observe...

journal_title：Clinical and experimental dermatology

authors： Davies MG,Hastings A

更新日期：1991-07-01 00:00:00

abstract：:Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficienc...

journal_title：Clinical and experimental dermatology

authors： Toms-Whittle LM,John LH,Buckley DA

更新日期：2011-04-01 00:00:00

abstract：:This randomized double-blind controlled study examined whether sulphydryl-containing agents influence the healing of venous ulceration occurring for the first time on the medial side of the leg. Graduated compression bandaging, which exerted a mean ankle pressure of 40.6 +/- 0.4 mmHg, and a mean below-knee pressure of...

journal_title：Clinical and experimental dermatology

authors： Salim AS

更新日期：1992-11-01 00:00:00

abstract：:In 1990 we reported the trends in presentation of malignant melanoma (MM) from 1986 to 1988 in a defined population in South Wales. Ten years after this initial study we reassessed the incidence of invasive MM in this defined population over a similar 3 year period. Using the local skin cancer registry we identified 1...

journal_title：Clinical and experimental dermatology

authors： Holme SA,Malinovsky K,Roberts DL

更新日期：2001-09-01 00:00:00

abstract：:A large variety of cutaneous reactions to malignancy have been described but to our knowledge none include psoriasis. Two cases of psoriasiform reactions in association with malignancy were first documented by Braverman, and Bazex's syndrome is now well documented in the literature. Both conditions, although clinicall...

journal_title：Clinical and experimental dermatology

authors： Hughes BR,Cotterill JA

更新日期：1993-01-01 00:00:00

abstract：:Hydroa vacciniforme (HV) is a rare photodermatosis first described by Bazin in the mid-nineteenth century. It typically presents in childhood and resolves during adolescence. Rarely, however, symptoms may persist into adult life.2,3 We now describe a patient with this condition presenting unusually for the first time ...

journal_title：Clinical and experimental dermatology

authors： Blackwell V,McGregor JM,Hawk JL

更新日期：1998-03-01 00:00:00

abstract：:An essential property of the immune system is its ability to generate diverse antibody and T-cell mediated responses to virtually any potential foreign particle. The basic molecular mechanisms responsible for producing this extensive diversity have now been elucidated. Each T cell expresses a unique membrane bound T-c...

journal_title：Clinical and experimental dermatology

authors： Whittaker S

更新日期：1996-03-01 00:00:00