Association of the interleukin-10 distal promoter (-2763A/C) polymorphism with late-onset psoriasis.

abstract：:Drug reactions are common in HIV-1 disease, with the incidence having been reported to increase with increasing stage and with CD4+ T-cell counts below 200/microliters. However, there have been numerous reports of patients in which rechallenge, dosing changes or continued therapy have resulted in no recurrence or else...

journal_title：Clinical and experimental dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,Ng TH,Wagner KF

更新日期：1997-05-01 00:00:00

abstract：:The Langerhans cells in the lentigines of four patients with the Leopard syndrome contained large membrane bound accumulations of melanin granules. Giant melanosomes were only seen in two patients. The patients had no immune-based symptoms relating to their lentigines. The Leopard Syndrome, also known as multiple lent...

journal_title：Clinical and experimental dermatology

authors： Fryer PR,Pope FM

更新日期：1992-01-01 00:00:00

abstract：:Glyceryl trinitrate (nitroglycerin) has been in use for relief of angina for over a hundred years, but allergic reactions to it or to other organic nitrates rarely feature in the medical literature. Most of the case reports describe reactions to transdermally applied nitroglycerin. We report a case of a localized alle...

journal_title：Clinical and experimental dermatology

authors： Aquilina S,Felice H,Boffa MJ

更新日期：2002-11-01 00:00:00

abstract：:Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

journal_title：Clinical and experimental dermatology

authors： Jones SA,Black MM

更新日期：1997-03-01 00:00:00

abstract：:We report a case of the rare porokeratosis variant porokeratosis ptychotropica (PP). A circumferential perianal plaque and the characteristic histology of multiple cornoid lamellae with underlying dermal amyloid deposition were seen. Amyloid deposition was seen in the biopsied intertriginous area of the plaque only, w...

journal_title：Clinical and experimental dermatology

authors： Tallon B,Blumental G,Bhawan J

更新日期：2009-12-01 00:00:00

abstract：:The effect of Anandron, a novel non-steroidal anti-androgen, on the reduction in sexual hair growth of 14 male-to-female transsexuals was investigated. Anandron (300 mg/day) alone for 8 weeks increased serum testosterone levels (mean: 19.2 +/- 6.1 to 44.9 +/- 11.5 mmol/l) and serum oestradiol levels (mean: 0.08 +/- 0....

journal_title：Clinical and experimental dermatology

authors： Asscheman H,Gooren LJ,Peereboom-Wynia JD

更新日期：1989-09-01 00:00:00

abstract：:The clinical characteristics associated with hidradenitis suppurativa (HS) severity are poorly understood. In this study, 124 patients with HS from 6 Italian dermatology centres participated in this study. Disease severity was assessed using the Hidradenitis Suppurativa Physician's Global Assessment score (HS-PGA) and...

journal_title：Clinical and experimental dermatology

authors： Bianchi L,Caposiena Caro RD,Ganzetti G,Molinelli E,Dini V,Oranges T,Romanelli M,Fabbrocini G,Monfrecola G,Napolitano M,Egan CG,Musumeci ML,Lacarrubba F,Micali G,Passoni E,Calzavara-Pinton PG,Venturini M,Zanca A,Offida

更新日期：2019-07-01 00:00:00

abstract：:It is a common experience that many Spitz naevi deviate from the idealized or stereotypical representation found in the literature, often causing considerable difficulties in distinguishing them from melanoma. The diagnostic term 'atypical Spitz naevus' is used to describe lesions that deviate from the typical appeara...

journal_title：Clinical and experimental dermatology

authors： de Giorgi V,Sestini S,Massi D,Papi F,Lotti T

更新日期：2008-05-01 00:00:00

abstract：:Dystrophic epidermolysis bullosa (DEB) is caused by mutations in the COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils. The characteristic genetic lesion in dominant DEB (DDEB) is a glycine substitution in the collagenous domain of the protein. In this study, we identified a Chinese fami...

journal_title：Clinical and experimental dermatology

authors： Zhang XJ,Song YX,Zhang XQ,Yang S,Li M,Li CR,Yang CJ,Yang J

更新日期：2003-07-01 00:00:00

abstract：:Ten psoriatic patients were treated with an accelerated PUVA regimen. Nine patients cleared in an average of 13.7 treatments (range 4-24) after an average total UVA dose of 83 J/cm2 (range 18-186). One patient had to withdraw due to pruritus and burning and six others had burning problems. The high incidence of burnin...

journal_title：Clinical and experimental dermatology

authors： Green C,George S,Lakshmipathi T,Ferguson J

更新日期：1993-07-01 00:00:00

abstract：:Guadeloupe is a French Caribbean island, with a population of mainly African ancestry, and a high standard of living. We recorded the dermatological diagnoses in 5000 new patients attending dermatologists. The main diagnoses were acne (16.4%), superficial mycoses (12.8%), and eczema (10.5%). Diseases considered to be ...

journal_title：Clinical and experimental dermatology

authors： Mahé A,Mancel E

更新日期：1999-09-01 00:00:00

abstract：:The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne th...

journal_title：Clinical and experimental dermatology

authors： Martin AR,Lookingbill DP,Botek A,Light J,Thiboutot D,Girman CJ

更新日期：2001-07-01 00:00:00

abstract：:Small tufts of chest hair were epilated at different rates and the roots classified as to growth phase, presence or absence of root sheaths and whether the shafts were fractured. With respect to anagen roots, a slow epilation gives bare roots whereas an increase in the rate of epilation increases the proportion of ens...

journal_title：Clinical and experimental dermatology

authors： Chapman DM

更新日期：1992-03-01 00:00:00

abstract：:A 68-year-old Caucasian male presented with a 5-week history of a widespread pruritic papular eruption. Histology from a papule on the left shoulder showed a dense dermal infiltrate of large mononuclear cells which were positive for leucocyte common antigen, KP1 and PGM1, with an MIB-1 proliferating fraction of 40%, d...

journal_title：Clinical and experimental dermatology

authors： Millard TP,Aitchison R,Wilkinson JD

更新日期：2003-03-01 00:00:00

abstract：:Desmoplastic trichoepithelioma (DT) is a rare benign adnexal neoplasm considered to have follicular differentiation. It usually presents as an asymptomatic, firm, annular plaque with a raised border. The most common site of occurrence is the face, usually on the cheek. Females are more often affected than males and th...

journal_title：Clinical and experimental dermatology

authors： Carter JJ,Kaur MR,Hargitai B,Brown R,Slator R,Abdullah A

更新日期：2007-09-01 00:00:00

abstract：:A patient with Darier's disease was discovered to have persistent, asymptomatic cervical and thoracic spinal hyperostoses after receiving isotretinoin for 7 years. The spinal abnormalities have remained asymptomatic but have now progressed following 4 years of etretinate therapy. The development of skeletal abnormalit...

journal_title：Clinical and experimental dermatology

authors： Archer CB,Elias PM,Lowe NJ,Griffiths WA

更新日期：1989-07-01 00:00:00

abstract：:Acne fulminans is characterized by the sudden onset of a severe, ulcerative acne associated with systemic features. Response to traditional acne therapies is poor. We have recognized a subset of patients with acne of a severity comparable to that of acne fulminans but with the absence of systemic involvement; we sugge...

journal_title：Clinical and experimental dermatology

authors： Thomson KF,Cunliffe WJ

更新日期：2000-06-01 00:00:00

abstract：:There is variation in the treatment of lower limb cellulitis (LLC) with no agreement on the most effective antibiotic regimen. Many patients with cellulitis fail to respond to first-line antibiotics. This can negatively affect patient care and result in unnecessary hospital admissions. The aim of this systematic revie...

journal_title：Clinical and experimental dermatology

authors： Mistry K,Sharma S,Patel M,Grindlay D,Janjuha R,Smart P,Levell NJ

更新日期：2021-01-01 00:00:00

abstract：:Twenty-six men who presented with male pattern baldness (androgen-dependent alopecia), were quantitatively evaluated for scalp hair variables and compared with 13 age-matched controls. Compared to controls, significant mean differences for hair variables were found in the frontal-vertex area, while in the occipital ar...

journal_title：Clinical and experimental dermatology

authors： Rushton DH,Ramsay ID,Norris MJ,Gilkes JJ

更新日期：1991-05-01 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：:A retrospective study was made of the incidence of cutaneous melanoma among the population of the district of Rijeka (Croatia) during the period 1977-96. A total of 397 patients with cutaneous melanoma was documented during this period. Over the 20-year period the incidence of the tumour increased, the mean annual rat...

journal_title：Clinical and experimental dermatology

authors： Zamolo G,Gruber F,Jonjić A,Cabrijan L,Palle M,Grubisić-Greblo H

更新日期：2000-01-01 00:00:00

abstract：:Contact allergy to various essential oils used in aromatherapy was demonstrated on patch testing in a 53-year-old patient suffering from relapsing eczema resistant to therapy on various uncovered parts of the skin, in particular the scalp, neck and hands. Sensitization was due to previous exposure to lavender, jasmine...

journal_title：Clinical and experimental dermatology

authors： Schaller M,Korting HC

更新日期：1995-03-01 00:00:00

abstract：:Langerhans cells at the site of patch tests to inhaled allergens in patients with atopic dermatitis were investigated. Within 24 h the Langerhans cells showed increased cellular activity and became apposed to mononuclear cells. This supports the view that Langerhans cells are involved in antigen presentation in atopic...

journal_title：Clinical and experimental dermatology

authors： Najem N,Hull D

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Atopic eczema (AE) is characterized by reduced skin hydration (SH) and impaired integrity of the skin. Proper emollient usage is an important facet of AE management and patients are encouraged to use emollients liberally. AIM:To evaluate whether the amount of emollient and skin cleanser used correlates with...

journal_title：Clinical and experimental dermatology

authors： Hon KL,Ching GK,Leung TF,Choi CY,Lee KK,Ng PC

更新日期：2010-01-01 00:00:00

abstract：:The therapeutic use of the induction of an allergic contact sensitivity to diphencyprone in alopecia areata has been studied. Fourteen subjects had alopecia totalis and four had extensive and long-standing alopecia areata. Topical diphencyprone was capable of inducing an allergic contact sensitivity in 16 subjects (89...

journal_title：Clinical and experimental dermatology

authors： Monk B

更新日期：1989-03-01 00:00:00

abstract：:Angiogenesis plays an important role in progression of various tumours including malignant melanoma. It is possible that the immunostaining of angiogenic markers could differentiate benign and malignant melanocytic lesions or that the immunostaining pattern with angiogenic markers could vary with tumour thickness and ...

journal_title：Clinical and experimental dermatology

authors： Dawn G,MacKie RM

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Acne vulgaris is a common chronic skin disease. Inflammation is an important pathogenetic mechanism of acne, and NLRP3 polymorphisms have been reported to be involved in the mediation and occurrence of the inflammation. However, only a few studies on NLRP3 and acne have been reported, and the mechanism remai...

journal_title：Clinical and experimental dermatology

authors： Shen C,Wang QZ,Shen ZY,Yuan HY,Yu WJ,Chen XD,Xu H

更新日期：2019-03-01 00:00:00

abstract：:Cryosurgery is an alternative treatment option to surgical excision for lentigo maligna. Clinical evidence of recurrence is usually characterized by repigmentation at the treated site. We report two patients who developed amelanotic malignant melanoma following cryosurgery for a pigmented lentigo maligna. These cases ...

journal_title：Clinical and experimental dermatology

authors： McKenna DB,Cooper EJ,Kavanagh GM,Davie RM,McLaren KM,Tidman MJ

更新日期：2000-11-01 00:00:00

abstract：:Neurotrophic ulceration of the face is a rare but well recognized sequel to division of the trigeminal nerve. Trauma is an important contributory factor and thought to be due in part to paraesthesiae, which encourages picking and scratching, with resultant chronic and persistent ulceration. A case is described of an 8...

journal_title：Clinical and experimental dermatology

authors： Mayer RD,Smith NP

更新日期：1993-03-01 00:00:00

abstract：:Although surgery may be curative in early malignant melanoma, its effect on survival lessens with each succeeding stage of the disease. A wide variety of immunological strategies have therefore been used to improve the prognosis of patients with malignant melanoma, but adjuvant therapy with interferon (IFN)-alpha is t...

journal_title：Clinical and experimental dermatology

authors： Russell-Jones R

更新日期：2000-01-01 00:00:00