Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3.

abstract：:Cutaneous amyloidosis and multiple endocrine neoplasia 2A (MEN 2A) have been previously reported in several families. A genetic linkage of both disorders has recently been described. Notalgia paraesthetica has been suggested to be involved in the aetiology of amyloidosis in such patients. We report such an association...

journal_title：Clinical and experimental dermatology

authors： de Argila D,Ortiz-Romero PL,Ortiz-Frutos J,Rodriguez-Peralto JL,Iglesias L

更新日期：1996-07-01 00:00:00

abstract：:A 48-year-old patient presented with a nonhealing leg ulcer and a raised white blood cell count. He was diagnosed with pyoderma gangrenosum (PG) and small lymphocytic leukaemia/chronic lymphocytic leukaemia (SLL/CLL). Eight months later, after undergoing treatment with chlorambucil for the SLL/CLL, and prednisone, cic...

journal_title：Clinical and experimental dermatology

authors： Branagan NM,Higgins SP,Halim SA,Le TH

更新日期：2009-07-01 00:00:00

abstract：:This is the first of two articles on C1 inhibitor deficiency based on a recent UK consensus document covering diagnosis and management of the disorder in both adults and children. This paper focuses on diagnosis of this disorder. ...

journal_title：Clinical and experimental dermatology

authors： Gompels MM,Lock RJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Identification of onychomycosis is mainly based on clinical diagnosis with auxiliary diagnostic methods such as potassium hydroxide (KOH) microscopy, periodic acid-Schiff staining or fungal culture. However, each method is limited by its sensitivity and specificity. AIM:To develop a new test method using th...

journal_title：Clinical and experimental dermatology

authors： Ho WT,Li Y,Yang S

更新日期：2019-06-01 00:00:00

abstract：:A 72-year-old woman with chronic renal failure requiring haemodialysis developed acute iododerma twice, after receiving iodide contrast dye for radiological procedures. Iododerma was localized to the face, scalp and elbows and was associated with papular purpura of the legs. Histopathology of the skin lesions showed a...

journal_title：Clinical and experimental dermatology

authors： Vaillant L,Pengloan J,Blanchier D,De Muret A,Lorette G

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Metallothioneins (MTs) are a group of proteins widely distributed in tissues regulating metal metabolism, scavenging free radicals, and taking part in immunological reactions. Knockout mice for MT genes I and II (MT(-/-)) exhibit reduced tolerance to ultraviolet B injury in vivo. Upregulation of MT proteins ...

journal_title：Clinical and experimental dermatology

authors： Ma C,Li LF,Zhang BX

更新日期：2007-07-01 00:00:00

abstract：:Multiple dermatofibromas (DFs) are rare and have been thought to be associated with altered immunity. In this report, we describe a 27-year-old Japanese woman with systemic lupus erythematosus (SLE) and Sjögren's syndrome in whom eight nodules appeared over a period of 4 years. Histopathological findings were consiste...

journal_title：Clinical and experimental dermatology

authors： Tsunemi Y,Tada Y,Saeki H,Ihn H,Tamaki K

更新日期：2004-09-01 00:00:00

abstract：:We describe a case of a 67-year-old woman with a 1-year history of nail thickening and a non-itchy erythematous scaly eruption on the fingertips. She was diagnosed with psoriasis and started on methotrexate after having had no response to topical calcipotriol. The diagnosis was reviewed after it was revealed by anothe...

journal_title：Clinical and experimental dermatology

authors： Goyal NN,Wong GA

更新日期：2008-03-01 00:00:00

abstract：:Burning mouth syndrome is characterized by an idiopathic burning pain affecting the oral mucosa, with no clinically apparent changes. It can present to a variety of health professionals including dermatologists. This article summarizes the important aspects of the condition, including theories of pathogenesis, diagnos...

journal_title：Clinical and experimental dermatology

authors： Lewis AK,Prime SS,Cohen SN

更新日期：2016-03-01 00:00:00

abstract：:Netherton syndrome (NS) is a rare and severe autosomal recessive ichthyosis. We report the case of a patient with NS treated successfully with narrowband ultraviolet B (NB-UVB) phototherapy after failure of low-dose oral isotretinoin. A 16-year-old girl born to consanguineous parents presented with severe ichthyosis. ...

journal_title：Clinical and experimental dermatology

authors： Maatouk I,Moutran R,Tomb R

更新日期：2012-06-01 00:00:00

abstract：:Three antituberculous drug regimens have been employed to study the therapeutic response in 90 patients with any one of the commonly encountered paucibacillary forms of skin tuberculosis, namely lupus vulgaris, tuberculosis verrucosa cutis and scrofuloderma. The first two regimens contained rifampicin, isoniazid and e...

journal_title：Clinical and experimental dermatology

authors： Ramesh V,Misra RS,Saxena U,Mukherjee A

更新日期：1991-03-01 00:00:00

abstract：:A case of Bowen's disease is described in which striking quantities of amyloid were detected in the papillary dermis visualized easily by routine haematoxylin and eosin staining. The material showed positive labelling with an antikeratin monoclonal antibody consistent with the proposed origin of the amyloid as degener...

journal_title：Clinical and experimental dermatology

authors： Speight EL,Milne DS,Lawrence CM

更新日期：1993-05-01 00:00:00

abstract：:Intravenous (IV) calcium is usually given to temporarily treat the effects of hyperkalaemia on muscle and heart. When extravasation of a calcium gluconate infusion occurs, there may be rapid and marked swelling and erythema, with signs of soft-tissue necrosis or infection, and ensuing extensive local calcification, ca...

journal_title：Clinical and experimental dermatology

authors： Celbek G,Gungor A,Albayrak H,Kir S,Guvenc SC,Aydin Y

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Intraoperative frozen section analysis (IFSA) is traditionally performed for complex and high-risk non-melanoma skin cancer (NMSC) resections, particularly when surgery under a general anaesthetic and a complex reconstruction is required, and where Mohs micrographic surgery (MMS) is not available. METHODS...

journal_title：Clinical and experimental dermatology

authors： Moncrieff MD,Shah AK,Igali L,Garioch JJ

更新日期：2015-12-01 00:00:00

abstract：:A 45-year-old man presented with a 7-year history of keratosis lichenoides chronica (KLC), a mucocutaneous lichenoid disorder of keratinization with no known aetiology, without significant systemic associations. Our patient also had type I diabetes mellitus, mild hypertension and lipid abnormalities. The diagnosis and...

journal_title：Clinical and experimental dermatology

authors： Wozniacka A,Schwartz RA,Omulecki A,Lesiak A,Sysa-Jedrzejowska A

更新日期：2006-01-01 00:00:00

abstract：:An essential property of the immune system is its ability to generate diverse antibody and T-cell mediated responses to virtually any potential foreign particle. The basic molecular mechanisms responsible for producing this extensive diversity have now been elucidated. Each T cell expresses a unique membrane bound T-c...

journal_title：Clinical and experimental dermatology

authors： Whittaker S

更新日期：1996-03-01 00:00:00

abstract：:We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

journal_title：Clinical and experimental dermatology

authors： Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

更新日期：2000-01-01 00:00:00

abstract：:Fourteen patients with psoriasis received long-term treatment with cyclosporin (CsA). Among patients there was great variability in the minimal effective CsA dose. In most patients long-term treatment was limited due to dose reductions made necessary because of side-effects. The therapeutic window for CsA seems small....

journal_title：Clinical and experimental dermatology

authors： Korstanje MJ,Van de Staak WJ

更新日期：1991-01-01 00:00:00

abstract：:The literature reveals what little is known about nutritional factors and hair loss. What we do know emanates from studies in protein-energy malnutrition, starvation, and eating disorders. In otherwise healthy individuals, nutritional factors appear to play a role in subjects with persistent increased hair shedding. H...

journal_title：Clinical and experimental dermatology

authors： Rushton DH

更新日期：2002-07-01 00:00:00

abstract：:We report a case of the rare porokeratosis variant porokeratosis ptychotropica (PP). A circumferential perianal plaque and the characteristic histology of multiple cornoid lamellae with underlying dermal amyloid deposition were seen. Amyloid deposition was seen in the biopsied intertriginous area of the plaque only, w...

journal_title：Clinical and experimental dermatology

authors： Tallon B,Blumental G,Bhawan J

更新日期：2009-12-01 00:00:00

abstract：:Summary Mid-dermal elastolysis is an unusual process characterized by the absence of the elastic fibres within the mid-dermis. The disappearance of these fibres causes fine wrinkles (type 1) or perifollicular protrusions (type 2) affecting the trunk, neck and arms. There is a female predilection, and most patients hav...

journal_title：Clinical and experimental dermatology

authors： Cutillas E,Ferrando FJ,Martí ME,Mateu A,Rausell N

更新日期：2010-07-01 00:00:00

abstract：:Actinic prurigo (AP) has been found to be strongly associated with HLA DR4 and in particular with the DR4 subtype DRB1*0407. However, AP may occur in the absence of HLA-DR4. Furthermore, it has been shown that HLA-DR4 and DRB1*0407, even in association with polymorphic light eruption (PLE), are insufficient for the ex...

journal_title：Clinical and experimental dermatology

authors： Grabczynska SA,Carey BS,McGregor JM,Hawk JL,Vaughan RW

更新日期：2001-11-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomas is an autosomal dominant condition that results in benign smooth muscle tumours of the skin and, in females, uterine fibroids. This syndrome overlaps with hereditary leiomyomatosis and renal cell cancer syndrome in which affected individuals may develop the rare type II papill...

journal_title：Clinical and experimental dermatology

authors： Chan I,Wong T,Martinez-Mir A,Christiano AM,McGrath JA

更新日期：2005-01-01 00:00:00

abstract：:We describe two patients with newly diagnosed dermatoses localizing to the radiotherapy field following treatment for breast cancer. Patient 1 was a 53-year-old woman who developed bullous morphoea on her left breast two years after radiotherapy. Patient 2 was a 43-year-old woman who developed urticaria pigmentosa on ...

journal_title：Clinical and experimental dermatology

authors： Hellen R,Kiely C,Murad A,Mulligan N,Coffey J,Lenane P,Moloney FJ

更新日期：2014-12-01 00:00:00

abstract：:Endogenous ochronosis or alkaptonuria is a rare, autosomal recessive disease of tyrosine metabolism that is caused by a deficiency of the enzyme homogentisic acid oxidase. The disease results in the accumulation and deposition of homogentisic acid in the cartilage, eyelids, forehead, cheeks, axillae, genital region, b...

journal_title：Clinical and experimental dermatology

authors： Turgay E,Canat D,Gurel MS,Yuksel T,Baran MF,Demirkesen C

更新日期：2009-12-01 00:00:00

abstract：:The Ras-Raf-MEK-ERK signalling pathway is frequently dysregulated in human malignancies, as is angiogenesis and the vascular endothelial growth factor receptor (VEGF/VEGFR) pathway. These kinases are therefore important anticancer targets. The novel, oral treatment sorafenib (BAY 43-9006), has been shown to be an inhi...

journal_title：Clinical and experimental dermatology

authors： Lacouture ME,Desai A,Soltani K,Petronic-Rosic V,Laumann AE,Ratain MJ,Stadler WM

更新日期：2006-11-01 00:00:00

abstract：:The clinical and histological effects of retinyl propionate cream (a retinyl ester) on extrinsic skin ageing (photo-ageing) in man were assessed in a double-blind randomized placebo-controlled study of 80 subjects, individual parameters of this being assessed for each treatment site (face, dorsal right forearm and han...

journal_title：Clinical and experimental dermatology

authors： Green C,Orchard G,Cerio R,Hawk JL

更新日期：1998-07-01 00:00:00

abstract：:Three patients with subungual exostoses, two involving the great toe and one the fourth toe, are presented. Local excision was performed, and the specimens were processed for light and electron microscopy. Light-microscopic study revealed that the tumours consisted of a proliferative fibrocartilaginous cap that merged...

journal_title：Clinical and experimental dermatology

authors： Kato H,Nakagawa K,Tsuji T,Hamada T

更新日期：1990-11-01 00:00:00

abstract：:We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one pat...

journal_title：Clinical and experimental dermatology

authors： Jacyk K,Smith A

更新日期：1990-09-01 00:00:00

abstract：:The case of an 80-year-old woman who developed extensive cutaneous calcification following intravenous phosphate administration is presented. Also the circumstances under which cutaneous calcification may occur are discussed. ...

journal_title：Clinical and experimental dermatology

authors： Mills CM,Knight AG

更新日期：1993-07-01 00:00:00