Increased protein oxidation and decreased expression of nuclear factor E2-related factor 2 protein in skin tissue of patients with diabetes.

abstract：:Three antituberculous drug regimens have been employed to study the therapeutic response in 90 patients with any one of the commonly encountered paucibacillary forms of skin tuberculosis, namely lupus vulgaris, tuberculosis verrucosa cutis and scrofuloderma. The first two regimens contained rifampicin, isoniazid and e...

journal_title：Clinical and experimental dermatology

authors： Ramesh V,Misra RS,Saxena U,Mukherjee A

更新日期：1991-03-01 00:00:00

abstract：:Paraneoplastic pemphigus (PNP) is an autoimmune blistering disease associated with neoplasms, typically lymphoproliferative disorders. PNP is characterized clinically by painful erosive stomatitis and polymorphous skin lesions. Histopathological findings are also very varied, and include lichen planus-like and pemphig...

journal_title：Clinical and experimental dermatology

authors： Gallo E,García-Martín P,Fraga J,Teye K,Koga H,Hashimoto T,García-Diez A

更新日期：2014-04-01 00:00:00

abstract：:The disaccharide content of the chondroitinase-digestible glycosaminoglycans (GAGs) extracted from 6-mm skin punch biopsies from the atrophic and sclerotic skin of two patients with Werner's syndrome (WS) were determined using high-performance liquid chromatography after 1-phenyl-3-methyl-5-pyrazolone labelling. The t...

journal_title：Clinical and experimental dermatology

authors： Higuchi T,Ishikawa O,Hayashi H,Ohnishi K,Miyachi Y

更新日期：1994-11-01 00:00:00

abstract：:Ectodermal dysplasias (ED) are developmental disorders affecting tissues of ectodermal origin including hair, nail, teeth and sweat glands. To date, four different types of ectodermal dysplasias involving only hair and nails have been described. In an effort to understand the molecular basis of ED of hair and nails, a...

journal_title：Clinical and experimental dermatology

authors： Naeem M,John P,Ali G,Ahmad W

更新日期：2007-09-01 00:00:00

abstract：:The case of a 40-year-old man with delusions of parasitosis as the presentation of a monodelusional psychosis is reported. In spite of treatment with pimozide and depot neuroleptics the patient committed suicide. Since the introduction of pimozide, this drug has come to be regarded as the specific treatment for this d...

journal_title：Clinical and experimental dermatology

authors： Monk BE,Rao YJ

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Both leprosy and human immunodeficiency virus (HIV) are infectious diseases, and are an important global health problem. Patients with leprosy who are co-infected with HIV seem to be at higher risk of developing leprosy reactions. AIM:To examine the histological features of leprosy in patients with HIV and ...

journal_title：Clinical and experimental dermatology

authors： Deps P,Lucas S,Porro AM,Maeda SM,Tomimori J,Guidella C,Reuter T,Oliveira NS,Madureira BP,Souza VA,Loureiro RM,Alves BL,Bellone A,Lockwood DN

更新日期：2013-07-01 00:00:00

abstract：:Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a condition that is seldom reported in the paediatric literature and rarely in the dermatological literature. It has other disparate and confusing names and as histology is rarely obtained, the condition may be under-reported. We describe this disorder in the...

journal_title：Clinical and experimental dermatology

authors： Flann S,Munn SE

更新日期：2009-06-01 00:00:00

abstract：:We describe the case of a 68-year-old woman who presented with asymptomatic skin nodules and symptoms of anaemia, and was found to have acute megakaryoblastic leukaemia with fibrosis, a condition now believed to correspond to the former diagnosis of acute myelofibrosis. There is only one previous report of skin lesion...

journal_title：Clinical and experimental dermatology

authors： Macfarlane AW,Parry DH,Caslin AW,Hughes M

更新日期：1996-05-01 00:00:00

abstract：:Three children (two boys and one girl) from the same family presented with photosensitivity, hyperpigmentation, hypertrichosis, mild skin fragility, blistering and scarring in childhood. On examination, the cutaneous lesions were found to have improved since their previous examinations. Laboratory tests showed raised ...

journal_title：Clinical and experimental dermatology

authors： Remenyik E,Lecha M,Badenas C,Kószó F,Vass V,Herrero C,Varga V,Emri G,Balogh A,Horkay I

更新日期：2008-08-01 00:00:00

abstract：:Lower eyelid involvement occurs in 6% of patients with discoid lupus erythematosus (DLE). Eyelid lesions are rarely the initial manifestation of DLE. We describe a 25-year-old woman presenting with discoid lesions of the lower eyelids, staphylococcal blepharitis and Meibomian gland dysfunction, who later developed a d...

journal_title：Clinical and experimental dermatology

authors： Ena P,Pinna A,Carta F

更新日期：2006-01-01 00:00:00

abstract：:Topical application of leukotriene-B4 (LTB4) on normal skin has been used as an in-vivo model to investigate cutaneous inflammation and epidermal proliferation, which are important phenomena in the pathogenesis of psoriasis. The aim of the present investigation is to further elucidate the interrelation between inflamm...

journal_title：Clinical and experimental dermatology

authors： de Jong EM,van Erp PE,van Vlijmen IM,van de Kerkhof PC

更新日期：1992-11-01 00:00:00

abstract：:A 93-year-old woman with an 8-year history of episodes of fixed drug eruption due to paracetamol is described. The rash was characterized by bullae, crusted lesions, hyperpigmented and erythematous patches as well as lesions resembling toxic epidermal necrolysis. Direct immunofluorescence revealed deposition of IgG an...

journal_title：Clinical and experimental dermatology

authors： Duhra P,Porter DI

更新日期：1990-07-01 00:00:00

abstract：:The Ras-Raf-MEK-ERK signalling pathway is frequently dysregulated in human malignancies, as is angiogenesis and the vascular endothelial growth factor receptor (VEGF/VEGFR) pathway. These kinases are therefore important anticancer targets. The novel, oral treatment sorafenib (BAY 43-9006), has been shown to be an inhi...

journal_title：Clinical and experimental dermatology

authors： Lacouture ME,Desai A,Soltani K,Petronic-Rosic V,Laumann AE,Ratain MJ,Stadler WM

更新日期：2006-11-01 00:00:00

abstract：:We present the case of a 68-year-old woman who developed a painful subcutaneous tumour in the sacral region. Histological examinations revealed a characteristic zonal pattern with a central zone of liquefactive necrosis, surrounded by proliferated atypical fibroblasts and prominent vessels, indicating ischaemic fascii...

journal_title：Clinical and experimental dermatology

authors： Kaneko T,Rokunohe D,Takiyoshi N,Minakawa S,Nakano H,Sawamura D

更新日期：2016-07-01 00:00:00

abstract：:Multiple dermatofibromas (DFs) are rare and have been thought to be associated with altered immunity. In this report, we describe a 27-year-old Japanese woman with systemic lupus erythematosus (SLE) and Sjögren's syndrome in whom eight nodules appeared over a period of 4 years. Histopathological findings were consiste...

journal_title：Clinical and experimental dermatology

authors： Tsunemi Y,Tada Y,Saeki H,Ihn H,Tamaki K

更新日期：2004-09-01 00:00:00

abstract：:Multiple cutaneous and uterine leiomyomas is an autosomal dominant condition that results in benign smooth muscle tumours of the skin and, in females, uterine fibroids. This syndrome overlaps with hereditary leiomyomatosis and renal cell cancer syndrome in which affected individuals may develop the rare type II papill...

journal_title：Clinical and experimental dermatology

authors： Chan I,Wong T,Martinez-Mir A,Christiano AM,McGrath JA

更新日期：2005-01-01 00:00:00

abstract：:It is only in the past 10 years that the allergenic potential of topical corticosteroids has been fully realized. This has an important impact on the management of patients with chronic eczematous eruptions. Nonhalogenated topical steroids are more frequent sensitizers than halogenated molecules. Tixocortol pivalate a...

journal_title：Clinical and experimental dermatology

authors： English JS

更新日期：2000-06-01 00:00:00

abstract：:We report a patient with purely cutaneous Rosai-Dorfman disease (RDD) who presented with a solitary, asymptomatic plaque on the back of her left thigh, with characteristic, large histiocytoid cells exhibiting emperipolesis histologically. Cutaneous lesions occur in 27% of patients with lymph node involvement in RDD ho...

journal_title：Clinical and experimental dermatology

authors： Child FJ,Fuller LC,Salisbury J,Higgins EM

更新日期：1998-01-01 00:00:00

abstract：:In this study we used the nickel contact allergy patch (CAP) test to investigate the effect of topical corticosteroids on allergic contact dermatitis (ACD). On day 1, three CAP tests were applied for 48 h on the forearms of 20 female volunteers with a known nickel ACD. CAP of the right forearm contained 5% nickel, and...

journal_title：Clinical and experimental dermatology

authors： Hachem JP,De Paepe K,Vanpée E,Bogaerts M,Kaufman L,Rogiers V,Roseeuw D

更新日期：2002-01-01 00:00:00

abstract：:Cutaneous amyloidosis and multiple endocrine neoplasia 2A (MEN 2A) have been previously reported in several families. A genetic linkage of both disorders has recently been described. Notalgia paraesthetica has been suggested to be involved in the aetiology of amyloidosis in such patients. We report such an association...

journal_title：Clinical and experimental dermatology

authors： de Argila D,Ortiz-Romero PL,Ortiz-Frutos J,Rodriguez-Peralto JL,Iglesias L

更新日期：1996-07-01 00:00:00

abstract：:Glyceryl trinitrate (nitroglycerin) has been in use for relief of angina for over a hundred years, but allergic reactions to it or to other organic nitrates rarely feature in the medical literature. Most of the case reports describe reactions to transdermally applied nitroglycerin. We report a case of a localized alle...

journal_title：Clinical and experimental dermatology

authors： Aquilina S,Felice H,Boffa MJ

更新日期：2002-11-01 00:00:00

abstract：:We describe two patients with newly diagnosed dermatoses localizing to the radiotherapy field following treatment for breast cancer. Patient 1 was a 53-year-old woman who developed bullous morphoea on her left breast two years after radiotherapy. Patient 2 was a 43-year-old woman who developed urticaria pigmentosa on ...

journal_title：Clinical and experimental dermatology

authors： Hellen R,Kiely C,Murad A,Mulligan N,Coffey J,Lenane P,Moloney FJ

更新日期：2014-12-01 00:00:00

abstract：:Two leprosy patients with neuritis caused by giant abscesses involving almost the entire ulnar nerve are described. One patient, who also had skin lesions, was diagnosed histopathologically as having borderline tuberculoid leprosy both on skin and nerve biopsy, and the other, with only nerve involvement, belonged to t...

journal_title：Clinical and experimental dermatology

authors： Saxena U,Ramesh V,Misra RS,Mukherjee A

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Topical tacrolimus has shown remarkable clinical efficacy in treating many dermatoses. Combining ultraviolet (UV) B and tacrolimus is an intriguing therapeutic regimen, especially for treatment of vitiligo, for which combination therapy may show greater clinical efficacy than topical tacrolimus alone. The ph...

journal_title：Clinical and experimental dermatology

authors： Lan CC,Yu HS,Huang SM,Wu CS,Kuo HY,Lee CH,Lin CS,Chen GS

更新日期：2010-03-01 00:00:00

abstract：:Naturally acquired anthrax infection remains an important public-health problem in developing countries. Turkey is one of the countries in which the zoonotic form of anthrax may still be encountered. The most frequent portal of entry for anthrax spores is the skin. Although cutaneous anthrax is usually self-limiting, ...

journal_title：Clinical and experimental dermatology

authors： Erkek E,Ayaslioglu E,Beygo B,Ozluk U

更新日期：2005-11-01 00:00:00

abstract：:Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per da...

journal_title：Clinical and experimental dermatology

authors： Tan A,Tan HH,Lee CC,Ng SK

更新日期：2003-05-01 00:00:00

abstract：:Acquired cold urticaria (ACU) is a frequent subtype of physical urticaria that is caused by the release of proinflammatory mast cell mediators after cold exposure. Although the underlying causes of ACU still remain to be clarified in detail, a wide range of diseases has been reported to be associated with ACU. This re...

journal_title：Clinical and experimental dermatology

authors： Siebenhaar F,Weller K,Mlynek A,Magerl M,Altrichter S,Vieira Dos Santos R,Maurer M,Zuberbier T

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Lichen sclerosus (LS) is a chronic inflammatory dermatosis with a predilection for the anogenital region, which mainly affects prepubertal girls and postmenopausal women. The cause is unknown, but a number of potential aetiological factors have been identified. AIM:To examine a cohort of patients with prepu...

journal_title：Clinical and experimental dermatology

authors： Ismail D,Owen CM

更新日期：2019-10-01 00:00:00

abstract：:Although surgery may be curative in early malignant melanoma, its effect on survival lessens with each succeeding stage of the disease. A wide variety of immunological strategies have therefore been used to improve the prognosis of patients with malignant melanoma, but adjuvant therapy with interferon (IFN)-alpha is t...

journal_title：Clinical and experimental dermatology

authors： Russell-Jones R

更新日期：2000-01-01 00:00:00

abstract：:Angiogenesis plays an important role in progression of various tumours including malignant melanoma. It is possible that the immunostaining of angiogenic markers could differentiate benign and malignant melanocytic lesions or that the immunostaining pattern with angiogenic markers could vary with tumour thickness and ...

journal_title：Clinical and experimental dermatology

authors： Dawn G,MacKie RM

更新日期：2002-03-01 00:00:00