Expression of CD39/Entpd1 on granuloma-composing cells and induction of Foxp3-positive regulatory T cells in sarcoidosis.

abstract：BACKGROUND:Topical tacrolimus has shown remarkable clinical efficacy in treating many dermatoses. Combining ultraviolet (UV) B and tacrolimus is an intriguing therapeutic regimen, especially for treatment of vitiligo, for which combination therapy may show greater clinical efficacy than topical tacrolimus alone. The ph...

journal_title：Clinical and experimental dermatology

authors： Lan CC,Yu HS,Huang SM,Wu CS,Kuo HY,Lee CH,Lin CS,Chen GS

更新日期：2010-03-01 00:00:00

abstract：:The effect of dietary supplementation with a combination of n-3 (marine oil) and n-6 (evening primrose oil) essential fatty acids in the treatment of chronic stable plaque psoriasis was observed. Thirty-seven patients in a double-blind parallel trial were studied. There was no significant improvement in clinical sever...

journal_title：Clinical and experimental dermatology

authors： Oliwiecki S,Burton JL

更新日期：1994-03-01 00:00:00

abstract：:Two patients presented with the unusual condition of multiple warty dyskeratomas on the scalp. Biopsies of affected skin stained positive with human keratin monoclonal antibodies HKN-6 and -7, specific for cortex and inner root sheath of normal human hair, respectively. Multiple warty dyskeratomas are a rare occurrenc...

journal_title：Clinical and experimental dermatology

authors： Griffiths TW,Hashimoto K,Sharata HH,Ellis CN

更新日期：1997-07-01 00:00:00

abstract：:Although many antihistamines are now in clinical use, few studies directly compare their pharmacodynamic and sedative activities in humans in vivo. We designed a double-blind, placebo-controlled, crossover study to compare the inhibitory effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-in...

journal_title：Clinical and experimental dermatology

authors： Takahashi H,Ishida-Yamamoto A,Iizuka H

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Therapeutics targeting tumour necrosis factor (TNF)-α are effective for psoriasis; however, in patients treated for other disorders, psoriasis may worsen and psoriasiform dermatitis (PsoD) may arise. T helper (Th) cytokines in psoriasis upregulate keratin (K)17, which modulates TNF-α transduction, leading to...

journal_title：Clinical and experimental dermatology

authors： Moy AP,Murali M,Kroshinsky D,Horn TD,Nazarian RM

更新日期：2018-01-01 00:00:00

abstract：:The effect of Anandron, a novel non-steroidal anti-androgen, on the reduction in sexual hair growth of 14 male-to-female transsexuals was investigated. Anandron (300 mg/day) alone for 8 weeks increased serum testosterone levels (mean: 19.2 +/- 6.1 to 44.9 +/- 11.5 mmol/l) and serum oestradiol levels (mean: 0.08 +/- 0....

journal_title：Clinical and experimental dermatology

authors： Asscheman H,Gooren LJ,Peereboom-Wynia JD

更新日期：1989-09-01 00:00:00

abstract：:Like many other cancers, melanoma has a significant genetic basis. However, its genetic pathways may involve multiple genes with probable interactions with sun exposure. Germline mutations in p16 or CDKN2A are found in a significant percentage of relatively rare melanoma families but p16 mutations are uncommon in spor...

journal_title：Clinical and experimental dermatology

authors： Bataille V

更新日期：2000-09-01 00:00:00

abstract：:In this study we used the nickel contact allergy patch (CAP) test to investigate the effect of topical corticosteroids on allergic contact dermatitis (ACD). On day 1, three CAP tests were applied for 48 h on the forearms of 20 female volunteers with a known nickel ACD. CAP of the right forearm contained 5% nickel, and...

journal_title：Clinical and experimental dermatology

authors： Hachem JP,De Paepe K,Vanpée E,Bogaerts M,Kaufman L,Rogiers V,Roseeuw D

更新日期：2002-01-01 00:00:00

abstract：:We present a case of paraneoplastic pemphigus associated with Castleman's disease. Our patient had stomatitis and vulvar erosions followed by a cutaneous polymorphous eruption. Investigations for neoplasia disclosed a Castleman's tumour suggesting the diagnosis of paraneoplastic pemphigus. The diagnosis was supported ...

journal_title：Clinical and experimental dermatology

authors： Caneppele S,Picart N,Bayle-Lebey P,Paul J,Irsutti M,Oksman F,Joly P,Bazex J

更新日期：2000-05-01 00:00:00

abstract：:A group of 23 patients with partial atrophic change of the tongue was examined for candidiasis. All of them reported pain in the tongue on eating hot or spicy food. The intensity of the tongue pain was evaluated before and after treatment using a visual analogue scale. Of the 23 patients, 10 (43.5%) had predisposing f...

journal_title：Clinical and experimental dermatology

authors： Terai H,Shimahara M

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Atopic eczema (AE) is characterized by reduced skin hydration (SH) and impaired integrity of the skin. Proper emollient usage is an important facet of AE management and patients are encouraged to use emollients liberally. AIM:To evaluate whether the amount of emollient and skin cleanser used correlates with...

journal_title：Clinical and experimental dermatology

authors： Hon KL,Ching GK,Leung TF,Choi CY,Lee KK,Ng PC

更新日期：2010-01-01 00:00:00

abstract：:Sweet's syndrome (acute febrile neutrophilic dermatosis, SS) may be considered a reactional dermatosis with numerous associated diseases. We describe a rare association between SS and acute sarcoidosis in a 55-year-old woman. The atypical feature of positive tuberculin reaction is discussed. In this association, diagn...

journal_title：Clinical and experimental dermatology

authors： Dadban A,Hirschi S,Sanchez M,Lagrange B

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Numerous studies have associated HS with obesity, and recently with metabolic syndrome (MetS). Both obesity and MetS are linked with metabolic changes. Thyroid hormones play a central role in metabolism and exert pleiotropic effects on adipogen...

journal_title：Clinical and experimental dermatology

authors： Miller IM,Vinding G,Sørensen HA,Rytgaard H,Mogensen UB,Ellervik C,Jemec GB

更新日期：2018-12-01 00:00:00

abstract：:Determining the risk of progression to systemic lupus erythematosus (SLE) among patients diagnosed with discoid lupus erythematosus (DLE), and the time frame of this risk, are important clinical questions. Past reports have demonstrated a wide time frame of progression from DLE to SLE, with mean time to progression of...

journal_title：Clinical and experimental dermatology

authors： Elman SA,Joyce C,Costenbader KH,Merola JF

更新日期：2020-01-01 00:00:00

abstract：:Dermatology services are largely outpatient based. Time for satisfactory patient communication is limited, with an average of around 15 min per new patient. The amount of new information that can be retained after verbal communication alone is limited during such consultations. One way to reinforce such information is...

journal_title：Clinical and experimental dermatology

authors： Tomkins CS,Braid JJ,Williams HC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:This is the first study investigating scabies treatment since 1992 to involve examination of patients with microscopically confirmed scabies. AIM:To assess the efficacy of 1% lindane cream in treating microscopically confirmed scabies, and to determine the utility of dermoscopy-guided skin scraping with mic...

journal_title：Clinical and experimental dermatology

authors： Park SE,Her Y,Kim SS,Kim CW

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Mortality from malignant melanoma (MM) has increased in Chile in the past decade. The location of MM lesions on the body has been correlated with prognosis and survival. AIM:To review body site and gender relationships with histopathologically confirmed primary MM in Chile. METHODS:Records of 575 cases pre...

journal_title：Clinical and experimental dermatology

authors： Zemelman V,Roa J,Tagle SR,Valenzuela CY

更新日期：2006-05-01 00:00:00

abstract：:Granuloma annulare and localized morphoea are both well described in the dermatological literature. We now present two patients with both of these diseases, a comorbidity rarely described. A possible pathogenic relationship is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Ben-Amitai D,Hodak E,Lapidoth M,David M

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

journal_title：Clinical and experimental dermatology

authors： Yue X,Wang A,Sun Y,Li Q

更新日期：2018-12-01 00:00:00

abstract：:A 33-year-old man with recessive dystrophic epidermolysis bullosa presented with a 3-month history of an enlarging mass within scarring on the posterior aspect of the right shoulder. The clinical appearance of the mass with an almost cobbled, verrucous surface, and its rapid evolution suggested the development of a sq...

journal_title：Clinical and experimental dermatology

authors： Orpin SD,Scott IC,Rajaratnam R,Colloby PS,Heagerty A

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). AIM:To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. METHODS:In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched ...

journal_title：Clinical and experimental dermatology

authors： Ucuz I,Altunisik N,Sener S,Turkmen D,Kavuran NA,Marsak M,Colak C

更新日期：2020-02-16 00:00:00

abstract：:Ectodermal dysplasias (ED) are developmental disorders affecting tissues of ectodermal origin including hair, nail, teeth and sweat glands. To date, four different types of ectodermal dysplasias involving only hair and nails have been described. In an effort to understand the molecular basis of ED of hair and nails, a...

journal_title：Clinical and experimental dermatology

authors： Naeem M,John P,Ali G,Ahmad W

更新日期：2007-09-01 00:00:00

abstract：:Myiasis is a condition resulting from the invasion of tissues or organs of man or animals by the larvae of dipterous flies. The distribution of myiasis is worldwide, with more cases being reported from tropical, subtropical, and warm temperate areas. The various forms of myiasis may be classified from an entomological...

journal_title：Clinical and experimental dermatology

authors： Delir S,Handjani F,Emad M,Ardehali S

更新日期：1999-07-01 00:00:00

abstract：:Rubinstein-Taybi syndrome (RSTS) is a rare congenital disorder, mainly characterized by postnatal growth retardation, intellectual disability, and facial and limb abnormalities. Although not considered as characteristic manifestations, numerous cutaneous anomalies have also been reported in patients with RSTS while th...

journal_title：Clinical and experimental dermatology

authors： Wang L,Deng Y,Zhou XL,Ma JJ,Li W

更新日期：2019-07-01 00:00:00

abstract：:It is well known that systemic corticosteroids arrest the progress of vitiligo and lead to repigmentation, but they may produce unacceptable side-effects. The use of high-dose prednisolone therapy to minimize the side-effects of systemic steroids has been reported, but there have been no reports on the effectiveness o...

journal_title：Clinical and experimental dermatology

authors： Lee Y,Seo YJ,Lee JH,Park JK

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) occurs in 10-25% of unselected patients starting highly active antiretroviral therapy (HAART). About 52-78% of these cases involve cutaneous features. AIM:To describe the prevalence and incidence of new dermatological conditions within 6 months of patients ...

journal_title：Clinical and experimental dermatology

authors： Osei-Sekyere B,Karstaedt AS

更新日期：2010-07-01 00:00:00

abstract：:Advances in molecular diagnostics have led to the feasibility of DNA-based prenatal testing in families at risk for recurrence of severe forms of both dystrophic and junctional epidermolysis bullosa. In this report, we describe prenatal testing in a woman who previously had a child affected with Herlitz junctional epi...

journal_title：Clinical and experimental dermatology

authors： Fassihi H,Ashton GH,Denyer J,Mellerio JE,Mason G,McGrath JA

更新日期：2005-03-01 00:00:00

abstract：:A 72-year-old woman with a 14-year history of urticarial vasculitis (UV) and a 13-year history of bullous pemphigoid (BP) presented with associated progressive chronic lymphocytic leukaemia (CLL). Both skin conditions responded poorly to treatment, until chemotherapy for CLL was commenced. The skin features showed a c...

journal_title：Clinical and experimental dermatology

authors： Kassim JM,Igali L,Levell NJ

更新日期：2015-06-01 00:00:00

abstract：:We present a patient with multiple leiomyomas confined to the left cheek, giving rise to an unusual clinical presentation of this condition. The lesions were cosmetically disfiguring and, because of their exposed location, were particularly painful in the winter months. The treatment of this condition is discussed. ...

journal_title：Clinical and experimental dermatology

authors： Tatnall FM,Leigh IM

更新日期：1990-07-01 00:00:00

abstract：:Acne fulminans is characterized by the sudden onset of a severe, ulcerative acne associated with systemic features. Response to traditional acne therapies is poor. We have recognized a subset of patients with acne of a severity comparable to that of acne fulminans but with the absence of systemic involvement; we sugge...

journal_title：Clinical and experimental dermatology

authors： Thomson KF,Cunliffe WJ

更新日期：2000-06-01 00:00:00