A rare case of recessive dystrophic epidermolysis bullosa and verruciform xanthoma.

abstract：:We report a rare case of cutaneous abscess by Trichosporon asahii in an immunocompetent adult. A 31-year-old Korean woman presented to our hospital with a cutaneous abscess. She had received an intralesional steroid injection 4 months earlier on the site of a hypertrophic scar. Direct sequencing of the intergenic spac...

journal_title：Clinical and experimental dermatology

authors： Yun SJ,Lee JB,Shin MG,Kim SJ,Won YH,Lee SC

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:In drug-induced toxic epidermal necrolysis (TEN), the epidermal destruction is associated with a slight to moderate lymphomonocytic cell infiltrate. Interleukin (IL)-8, which is a keratinocyte-derived pro-inflammatory cytokine, might be involved in this process. The IL-8 receptor CXCR2 has also been shown to...

journal_title：Clinical and experimental dermatology

authors： Paquet P,Ribbens C,Piérard GE

更新日期：2007-11-01 00:00:00

abstract：:This is the first of two articles on C1 inhibitor deficiency based on a recent UK consensus document covering diagnosis and management of the disorder in both adults and children. This paper focuses on diagnosis of this disorder. ...

journal_title：Clinical and experimental dermatology

authors： Gompels MM,Lock RJ

更新日期：2005-07-01 00:00:00

abstract：:We present a 23-year-old woman with a diagnosis of keratolytic winter erythema (erythrokeratolysis hiemalis), who developed facial lesions following a traumatic experience. This rare genodermatosis usually affects the palms and soles, and appears as mild erythema and annular scaling. The limbs and trunk can rarely be ...

journal_title：Clinical and experimental dermatology

authors： Degiovanni CV,Farrant PB,Howell S,Hull PR,Woollons A

更新日期：2009-03-01 00:00:00

abstract：:Malignant eccrine spiradenoma (MES) is an extremely rare cutaneous malignant tumour. An 86-year-old man presented at our hospital with an enlarging tumour on the dorsum of the left hand. An excisional biopsy was taken and histological examination showed a solid island of cells of two distinct types: cells with abundan...

journal_title：Clinical and experimental dermatology

authors： Tanese K,Sato T,Ishiko A

更新日期：2010-01-01 00:00:00

abstract：:Familial occurrence of Jessner's lymphocytic infiltration of the skin is reported in a father and daughter. A definitive diagnosis of Jessner's disease was greatly facilitated by the presence of large numbers of plasmacytoid monocytes within the dermal infiltrates in both patients. A role for skin-directed lymphocyte ...

journal_title：Clinical and experimental dermatology

authors： Toonstra I,van der Putte SC,de la Faille HB,van Vloten WA

更新日期：1993-03-01 00:00:00

abstract：:Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica of...

journal_title：Clinical and experimental dermatology

authors： Owen CM,Murphy H,Yates VM

更新日期：2001-03-01 00:00:00

abstract：:Pityriasis rotunda (PR) is an uncommon chronic dermatosis, which may be idiopathic or may be associated with infections or malignancy. We describe the clinical and biochemical findings of two patients with multiple myeloma, who were incidentally diagnosed with PR, and detail the clinical conditions with which this rar...

journal_title：Clinical and experimental dermatology

authors： van Heerden T,Webb MJ,Barrett CL

更新日期：2014-08-01 00:00:00

abstract：:Systemic sclerosis (SSc) is often complicated by severe skin ulcers that are unresponsive to traditional treatments. Vascular alterations are responsible for the ischaemic features of the disease in both the skin and visceral organs. Defective neoangiogenesis correlates with an abnormally reduced quantity of circulati...

journal_title：Clinical and experimental dermatology

authors： Ferri C,Giuggioli D,Manfredi A,Quirici N,Scavullo C,Colaci M,Gianelli U,Deliliers GL,Del Papa N

更新日期：2010-12-01 00:00:00

abstract：:The precursor protein proopiomelanocortin (POMC) produces many biologically active peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and beta-endorphin. The gene for alpha-MSH is encoded for by the POMC gene, but alpha-MSH c...

journal_title：Clinical and experimental dermatology

authors： Millington GW

更新日期：2006-05-01 00:00:00

abstract：:Drug reactions are common in HIV-1 disease, with the incidence having been reported to increase with increasing stage and with CD4+ T-cell counts below 200/microliters. However, there have been numerous reports of patients in which rechallenge, dosing changes or continued therapy have resulted in no recurrence or else...

journal_title：Clinical and experimental dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,Ng TH,Wagner KF

更新日期：1997-05-01 00:00:00

abstract：:Black hairy tongue is the name given to the appearance of an abnormal coating of the tongue and occurs only in adults. It is the result of hyperkeratosis of the filiform lingual papillae which, on gross examination appear hair-like with a variable tinctorial aspect from yellow-brown to black. The pathogenesis is unkno...

journal_title：Clinical and experimental dermatology

authors： Langtry JA,Carr MM,Steele MC,Ive FA

更新日期：1992-05-01 00:00:00

abstract：:Acquired dermal melanocytosis (ADM) is a relatively rare, but well-described disease among adolescent to middle-aged East Asian women, particularly those of Japanese and Chinese descent. Clinically, ADM manifests as multiple punctate and greyish-brown pigmented areas 1-3 mm in diameter occurring on both sides of the f...

journal_title：Clinical and experimental dermatology

authors： Ouchi T,Ishii K,Nishikawa T,Ishiko A

更新日期：2016-08-01 00:00:00

abstract：:Paraneoplastic pemphigus (PNP) is an autoimmune blistering disease associated with neoplasms, typically lymphoproliferative disorders. PNP is characterized clinically by painful erosive stomatitis and polymorphous skin lesions. Histopathological findings are also very varied, and include lichen planus-like and pemphig...

journal_title：Clinical and experimental dermatology

authors： Gallo E,García-Martín P,Fraga J,Teye K,Koga H,Hashimoto T,García-Diez A

更新日期：2014-04-01 00:00:00

abstract：:Tender nodules may develop at the site of injection of allergen extracts. Some cases can be related to the aluminium contained in the preparation. We report a case where scar sarcoidosis developed at the site of desensitization injections. At presentation, there were no other cutaneous signs of sarcoidosis; systemic s...

journal_title：Clinical and experimental dermatology

authors： Healsmith MF,Hutchinson PE

更新日期：1992-09-01 00:00:00

abstract：:Xanthomas are important clinical manifestations of disordered lipid metabolism, which are mostly found in patients with familial hypercholesterolaemia (FH), an inherited disorder that is predominantly caused by mutations in the low-density lipoprotein receptor gene (LDLR). Tuberous and tendinous xanthomas with wide di...

journal_title：Clinical and experimental dermatology

authors： Kong MX,Zhang Q,Cao L,Zhao C,Ru GQ,Bi Q

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Vitiligo is a skin disease characterized by loss of normal pigmentation in the skin. Several treatments exist but none is really effective. Recently, perturbations of calcium homeostasis in vitiliginous epidermis have been described. AIM:Based on these findings, the aim of this prospective, randomized, open...

journal_title：Clinical and experimental dermatology

authors： Leone G,Pacifico A,Iacovelli P,Paro Vidolin A,Picardo M

更新日期：2006-03-01 00:00:00

abstract：:Common unifying features of the subepidermal blistering diseases are the presence of tense blisters clinically and demonstration by immunofluorescence of linear deposition of immunoreactants along the dermoepidermal junction. Further characterization of subtype is possible by identification of the target antigen by im...

journal_title：Clinical and experimental dermatology

authors： Rao R,Bhogal B,Groves R

更新日期：2013-04-01 00:00:00

abstract：:A group of patients who attended dermatology clinics in Northern Ireland between 1960 and 1970 with a diagnosis of infantile acne was compared with a similar age-matched control group of 160 medical students. The severity of the acne was judged according to the form of treatment required--topical treatment, systemic a...

journal_title：Clinical and experimental dermatology

authors： Chew EW,Bingham A,Burrows D

更新日期：1990-09-01 00:00:00

abstract：:It is well known that primary systemic amyloidosis [light chain (AL) amyloidosis] is associated with hidden dyscrasia or multiple myeloma. Acquired cutis laxa (cutis laxa acquisita; CLA) has also been described in patients with plasma cell dyscrasias, including multiple myeloma. We report a case in which haemorrhagic ...

journal_title：Clinical and experimental dermatology

authors： Gonzalez-Ramos J,Garrido-Gutiérrez C,González-Silva Y,Yébenes-Gregorio L,Beato-Merino M,Vidaurrázaga-Arcaya C,Herranz-Pinto P

更新日期：2017-06-01 00:00:00

abstract：:We report a case of a 56-year-old woman who presented with a severe exacerbation of psoriasis with concurrent hypoglycaemic episodes. Methotrexate 17.5 mg weekly was required to control her psoriasis. Investigation of her hypoglycaemia showed raised levels of insulin, C-peptide and proinsulin. Radiological investigati...

journal_title：Clinical and experimental dermatology

authors： Field S,Kelly G,Tobin AM,Barragry JM,Conlon KC,Kirby B

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an organ-specific autoimmune disease characterized by folliculotropic T-cell infiltrates around anagen-stage hair follicles. The role of T helper (Th)1 and Th2 cytokines in the pathogenesis of AA have not been established. AIM:To determine whether serum cytokine profiles define the s...

journal_title：Clinical and experimental dermatology

authors： Barahmani N,Lopez A,Babu D,Hernandez M,Donley SE,Duvic M

更新日期：2010-06-01 00:00:00

abstract：:A 72-year-old woman with chronic renal failure requiring haemodialysis developed acute iododerma twice, after receiving iodide contrast dye for radiological procedures. Iododerma was localized to the face, scalp and elbows and was associated with papular purpura of the legs. Histopathology of the skin lesions showed a...

journal_title：Clinical and experimental dermatology

authors： Vaillant L,Pengloan J,Blanchier D,De Muret A,Lorette G

更新日期：1990-05-01 00:00:00

abstract：:Lupus miliaris disseminatus faciei (LMDF) is a chronic and uncommon inflammatory dermatosis, characterized by yellowish-red papules, especially on the face and around the eyelids. It is considered to be a reaction to destroyed hair follicles. We dermoscopically evaluated two patients diagnosed with LMDF. Dermoscopy re...

journal_title：Clinical and experimental dermatology

authors： Ayhan E,Alabalik U,Avci Y

更新日期：2014-06-01 00:00:00

abstract：:We report the occurrence of severe symptomatic bronchoconstriction in an atopic asthmatic subject following the application of coal tar bandages. Investigations showed that this was likely to have been caused by inhalation of coal tar vapour. We suggest that coal tar preparations should be used with caution in asthmat...

journal_title：Clinical and experimental dermatology

authors： Ibbotson SH,Stenton SC,Simpson NB

更新日期：1995-01-01 00:00:00

abstract：:Cryosurgery is an alternative treatment option to surgical excision for lentigo maligna. Clinical evidence of recurrence is usually characterized by repigmentation at the treated site. We report two patients who developed amelanotic malignant melanoma following cryosurgery for a pigmented lentigo maligna. These cases ...

journal_title：Clinical and experimental dermatology

authors： McKenna DB,Cooper EJ,Kavanagh GM,Davie RM,McLaren KM,Tidman MJ

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Several studies have shown that in Africa squamous cell carcinoma (SCC) is commoner than other skin malignancies. The risk factors are grouped generally into solar and nonsolar factors and their contributions vary with race, geographical region and site of lesion. This study attempted to identify risk factor...

journal_title：Clinical and experimental dermatology

authors： Asuquo ME,Udosen AM,Ikpeme IA,Ngim NE,Otei OO,Ebughe G,Bassey EE

更新日期：2009-12-01 00:00:00

abstract：:Renal itch is localized or generalized itch, affecting patients with chronic renal failure, where there is no primary skin disease and no systemic or psychological dysfunction that might cause pruritus. It does not result from raised serum urea levels. The prevalence of renal itch has increased with the growing popula...

journal_title：Clinical and experimental dermatology

authors： Murphy M,Carmichael AJ

更新日期：2000-03-01 00:00:00

abstract：:A retrospective case series of 53 female patients with incontinentia pigmenti (IP) including 28 secondary cases (female relatives of probands) was reviewed and compared with other series in an attempt to estimate more accurately the true disease burden of patients with IP. We found that, while the frequency of the fir...

journal_title：Clinical and experimental dermatology

authors： Phan TA,Wargon O,Turner AM

更新日期：2005-09-01 00:00:00

abstract：:A lighter or whiter complexion is socially desirable in many cultures. This has led to an unregulated and highly profitable market in skin-lightening creams that are readily available over the counter or on the internet. Plant extracts and newer tyrosinase inhibitors such as kojic acid or its derivative kojic dipalmit...

journal_title：Clinical and experimental dermatology

authors： Madhogaria S,Ahmed I

更新日期：2010-06-01 00:00:00