Abstract：
:Cutaneous leishmaniasis (CL) in western countries seems to be appearing more frequently. Our aim was to determine if there has been a shift in countries where CL is acquired and whether the incidence has changed, and to assess current diagnostic procedures and treatment modalities. In a retrospective study medical records of patients with the diagnosis of CL at the Departments of Tropical Dermatology and Tropical Medicine, Academic Medical Center, Amsterdam, the Netherlands, from 1990 to 2000 were analysed. CL was diagnosed in 78 patients. The majority was acquired in Belize, Surinam, French Guyana and Bolivia. Giemsa stains were positive for the parasite in impression smears from 43% and in biopsies from 71%. Seventy-eight per cent of cases were culture-positive and 89% were PCR-positive. Sixty-two patients were treated systemically: pentavalent antimony (32), pentamidine isetionate (11), itraconazole (19), and 13 locally, the majority with a combination of cryosurgery and intralesional pentavalent antimony. Imported CL is becoming more frequent, with South and Middle American countries being important sources of infection. Multiple tests, of which PCR is the most sensitive, are required to confirm the diagnosis. Systemic treatment was given to the majority of the patients.
journal_name
Clin Exp Dermatoljournal_title
Clinical and experimental dermatologyauthors
Zeegelaar JE,Steketee WH,van Thiel PP,Wetsteyn JC,Kager PA,Faber WRdoi
10.1111/j.1365-2230.2004.01677.xkeywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
1-5issue
1eissn
0307-6938issn
1365-2230pii
CED1677journal_volume
30pub_type
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journal_title：Clinical and experimental dermatology
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doi：10.1111/j.1365-2230.2008.03117.x
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journal_title：Clinical and experimental dermatology
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更新日期：2008-08-01 00:00:00
