A novel, simple, validated and reproducible instrument for assessing provocation threshold levels in patients with symptomatic dermographism.

Abstract:

BACKGROUND:Symptomatic dermographism is a common urticarial condition. There is a need for an objective method to determine the provocation threshold for patients, in order to facilitate individualized diagnosis and treatment. AIM:To compare the dermal responses evoked by a new type of dermographometer (FricTest) with those evoked by a spring-loaded dermographometer (the Dermographic tester). METHODS:Dermal provocation was performed in 30 patients with symptomatic dermographism and 30 healthy controls. The FricTest consists of six tips of varying length, which are stroked over the skin, while the Dermographic tester has a single tip. The widths and volumes of the resulting weals were measured. RESULTS:Both instruments were similar in their ability to produce dermal responses. The weal widths of 1 and 3 mm induced by the FricTest were used as the provocation thresholds to distinguish between patients and controls, and to indicate the different levels of severity within the patient group. CONCLUSIONS:The FricTest was easy to use and produced an objective response. This simple and inexpensive instrument could be used to individualize diagnosis and treatment of patients with symptomatic dermographism, allowing for better personalized management.

journal_name

Clin Exp Dermatol

authors

Mlynek A,Vieira dos Santos R,Ardelean E,Weller K,Magerl M,Church MK,Maurer M

doi

10.1111/ced.12107

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

360-6; quiz 366

issue

4

eissn

0307-6938

issn

1365-2230

journal_volume

38

pub_type

杂志文章
  • Dermoscopic features in fungal melanonychia.

    abstract:BACKGROUND:Data on the dermoscopic features of fungal melanonychia are limited. AIM:To identify the dermoscopic features of fungal melanonychia. METHODS:We reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past y...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12552

    authors: Kilinc Karaarslan I,Acar A,Aytimur D,Akalin T,Ozdemir F

    更新日期:2015-04-01 00:00:00

  • Allergic contact dermatitis in children; has there been a change in allergens?

    abstract::Allergic contact dermatitis (ACD) is now recognized as a common relevant diagnosis in children. We reviewed the results of patch tests in children under 16 years of age over the 3-year period January 2009 to December 2011, comparing the results with those in a similar 3-year retrospective study performed in our unit f...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12460

    authors: Vongyer GA,Green C

    更新日期:2015-01-01 00:00:00

  • T-cell receptor gene analysis in cutaneous T-cell lymphomas.

    abstract::An essential property of the immune system is its ability to generate diverse antibody and T-cell mediated responses to virtually any potential foreign particle. The basic molecular mechanisms responsible for producing this extensive diversity have now been elucidated. Each T cell expresses a unique membrane bound T-c...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:

    authors: Whittaker S

    更新日期:1996-03-01 00:00:00

  • Androgenic alopecia and insulin resistance: are they really related?

    abstract:BACKGROUND:Androgenic alopecia is known to be androgen-dependent. Insulin is found in hair follicles and may play a role in the regulation of androgen metabolism and the hair-growth cycle. OBJECTIVES:To compare the insulin resistance between people with androgenic alopecia and a control group. METHODS:A case-control ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2230.2008.03118.x

    authors: Nabaie L,Kavand S,Robati RM,Sarrafi-Rad N,Kavand S,Shahgholi L,Meshkat-Razavi G

    更新日期:2009-08-01 00:00:00

  • Imiquimod 5% cream versus timolol 0.5% ophthalmic solution for treating superficial proliferating infantile haemangiomas: a retrospective study.

    abstract:BACKGROUND:Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM:To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS:The medical records of all the patients with p...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12150

    authors: Qiu Y,Ma G,Yang J,Hu X,Chen H,Jin Y,Lin X

    更新日期:2013-12-01 00:00:00

  • Dorfman-Chanarin syndrome (neutral lipid storage disease). A case report.

    abstract::We describe the case of a woman from a small town in the south of Spain, with consanguineous parents, who presented with the complete syndrome. The main clinicopathological characteristics are discussed. ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.1994.tb02705.x

    authors: Bañuls J,Betlloch I,Botella R,Sevila A,Morell A,Román P

    更新日期:1994-09-01 00:00:00

  • The course of pregnancy and childbirth in three mothers with recessive dystrophic epidermolysis bullosa.

    abstract:BACKGROUND:Recessive dystrophic epidermolysis bullosa (RDEB) is an autosomal recessive skin disease caused by mutations in the type VII collagen gene (COL7A1), resulting in detachment of the entire epidermis due to loss or hypoplasticity of the anchoring fibrils that normally secure the basement membrane to the underly...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2011.04179.x

    authors: Hanafusa T,Tamai K,Umegaki N,Yamaguchi Y,Fukuda S,Nishikawa Y,Yaegashi N,Okuyama R,McGrath JA,Katayama I

    更新日期:2012-01-01 00:00:00

  • Juvenile colloid milium associated with ligneous conjunctivitis: report of a case and review of the literature.

    abstract::Juvenile colloid milium is an extremely rare skin condition with an onset prior to puberty; it can be distinguished histologically from the adult form. We report a case of juvenile colloid milium associated with ligneous conjunctivitis and gingival deposits of an amyloid-like homogenous eosinophilic material. We hypot...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2230.2000.00597.x

    authors: Chowdhury MM,Blackford S,Williams S

    更新日期:2000-03-01 00:00:00

  • Do dermatology outpatients value a copy of the letter sent to their general practitioner? In what way and at what cost?

    abstract::Dermatology services are largely outpatient based. Time for satisfactory patient communication is limited, with an average of around 15 min per new patient. The amount of new information that can be retained after verbal communication alone is limited during such consultations. One way to reinforce such information is...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2004.01437.x

    authors: Tomkins CS,Braid JJ,Williams HC

    更新日期:2004-01-01 00:00:00

  • Co-existence of lichen amyloidosus and angiolymphoid hyperplasia with eosinophilia.

    abstract::Summary Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon benign vascular tumour. It presents with small, dull red papules or nodules usually on the ears and preauricular areas and only 20% of lesions are multiple. We report a case of multiple scattered lesions of ALHE in a patient who subsequently dev...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2004.01517.x

    authors: Shankar S,Russell-Jones R

    更新日期:2004-07-01 00:00:00

  • Teledermatology in practice.

    abstract::Teledermatology has been the focus of much interest in recent years. Potential uses include a simple supporting role for primary care, more accurate triage of dermatology patients or an 'advice only' service reducing the need for dermatology patients to attend outpatient clinics. With the current under-provision of de...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2003.01313.x

    authors: Mallett RB

    更新日期:2003-07-01 00:00:00

  • Acquired crateriform hyperkeratotic papules of the lower limbs: an unusual variant of acrokeratoelastoidosis of Costa.

    abstract::We report a man with a 3-year-history of a striking eruption of small, 2-3 mm diameter keratotic, crateriform papules distributed symmetrically over the lower limbs. Morphologically the individual papules closely resembled those described in acrokeratoelastoidosis (AK) of Costa and in focal acral hyperkeratosis of Dow...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2001.00810.x

    authors: Helbling I,Tucker SC,Chalmers RJ

    更新日期:2001-05-01 00:00:00

  • Co-occurrence of Aicardi-Goutières syndrome type 6 and dyschromatosis symmetrica hereditaria due to compound heterozygous pathogenic variants in ADAR1: a case series from India.

    abstract::Aicardi-Goutières syndrome type 6 (AGS6) and dyschromatosis symmetrica hereditaria (DSH) are allelic disorders caused respectively by biallelic and heterozygous pathogenic variants in ADAR1. We report three unrelated children presenting with features of both AGS6 and DSH, two of whom had compound heterozygous pathogen...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.14531

    authors: Sathishkumar D,Muthusamy K,Gupta A,Malhotra M,Thomas M,Koshy B,Jasper A,Danda S,George R

    更新日期:2020-12-07 00:00:00

  • Laser therapy of telangiectatic leg veins: clinical evaluation of the 810 nm diode laser.

    abstract::Telangiectatic leg veins (TLV) are experienced by millions of women and men. As they cause significant cosmetic embarrassment, many women seek effective treatment. Options include sclerotherapy and treatment with different lasers. We investigated the safety and efficacy of an 810-nm diode laser in the treatment of TLV...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2000.00679.x

    authors: Varma S,Lanigan SW

    更新日期:2000-07-01 00:00:00

  • Clinical and histological features of leprosy and human immunodeficiency virus co-infection in Brazil.

    abstract:BACKGROUND:Both leprosy and human immunodeficiency virus (HIV) are infectious diseases, and are an important global health problem. Patients with leprosy who are co-infected with HIV seem to be at higher risk of developing leprosy reactions. AIM:To examine the histological features of leprosy in patients with HIV and ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12028

    authors: Deps P,Lucas S,Porro AM,Maeda SM,Tomimori J,Guidella C,Reuter T,Oliveira NS,Madureira BP,Souza VA,Loureiro RM,Alves BL,Bellone A,Lockwood DN

    更新日期:2013-07-01 00:00:00

  • Ultrastructural changes of Trichophyton rubrum in tinea unguium after itraconazole therapy in vivo observed using scanning electron microscopy.

    abstract:BACKGROUND:Tinea unguium is a dermatophyte infection of the nails. Itraconazole is a broad-spectrum antifungal drug used to treat this disease. It works by interfering with the synthesis of ergosterol in the cell membrane, thus causing changes that can be seen under scanning electron microscopy (SEM). AIM:To observe u...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13641

    authors: Yue X,Wang A,Sun Y,Li Q

    更新日期:2018-12-01 00:00:00

  • Asymmetrical periflexural exanthem exhibiting pseudoisomorphic Köebner response in an adult.

    abstract::Asymmetrical periflexural exanthem is a rare clinical condition, seen almost exclusively in children. Very few adult cases have been reported in the literature. We report a case of this rare eruption in an adult man showing characteristic clinical and histological features. Interestingly, this patient also exhibited a...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2008.03053.x

    authors: Dar NR,Raza N

    更新日期:2009-10-01 00:00:00

  • Dermatological manifestations of Down's syndrome.

    abstract::Down's syndrome (DS) is associated with rare dermatological disorders and increased frequency of some common dermatoses. Owing to advances in medical care and changes in attitude, the median age of death in this population has increased to 49 years, and the life expectancy of a 1-year-old person with DS today is more ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2230.2006.02164.x

    authors: Madan V,Williams J,Lear JT

    更新日期:2006-09-01 00:00:00

  • The value of direct immunofluorescence as a diagnostic aid in dermatomyositis--a study of 35 cases.

    abstract::Dermatomyositis (DM) in a inflammatory disorder of skeletal muscle and skin closely related to other connective tissue diseases; however, to date, no conclusive immunofluorescence (IMF) data are available for the disorder. The aim of this study was therefore to analyse retrospectively the clinical, histological and di...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:

    authors: Jones SA,Black MM

    更新日期:1997-03-01 00:00:00

  • Combined cutaneous hamartoma encompassing benign melanocytic naevus, vellus hair cyst and epidermoid cyst.

    abstract::We describe a combined cutaneous hamartoma in a 57-year-old man, which comprised a vellus hair cyst, an epidermoid cyst and an intradermal melanocytic naevus in a single facial tumour. The vellus hair cyst was filled with keratinous material with unusual slit-like lacunae. While numerous cases of epidermoid cyst have ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2000.00569.x

    authors: Tsuruta D,Nakagawa K,Taniguchi S,Kobayashi H,Hamada T,Ishii M

    更新日期:2000-01-01 00:00:00

  • Nutritional factors and hair loss.

    abstract::The literature reveals what little is known about nutritional factors and hair loss. What we do know emanates from studies in protein-energy malnutrition, starvation, and eating disorders. In otherwise healthy individuals, nutritional factors appear to play a role in subjects with persistent increased hair shedding. H...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2230.2002.01076.x

    authors: Rushton DH

    更新日期:2002-07-01 00:00:00

  • Results of computer-assisted sensory evaluation in 41 patients with erythromelalgia.

    abstract:BACKGROUND:Erythromelalgia is a rare disorder characterized by the clinical syndrome of burning pain, warmth and redness of the limbs. Neurological abnormalities (both large- and small-fibre neuropathy) are common. There have been few published reports on the sensory status of patients with erythromelalgia. AIM:To inv...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2011.04330.x

    authors: Genebriera J,Michaels JD,Sandroni P,Davis MD

    更新日期:2012-06-01 00:00:00

  • The A/A genotype of an interleukin-17A polymorphism predisposes to increased severity of atopic dermatitis and coexistence with asthma.

    abstract:INTRODUCTION:Studies have found that the interleukin-23/T helper 17 (IL-23/Th17) pathway plays an important role in the pathogenesis of atopic dermatitis (AD). Inhibition of the IL-23/Th17 pathway with monoclonal antibodies reduces skin inflammation in animal models. AIM:To investigate the association between IL-17A a...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.12438

    authors: Narbutt J,Wojtczak M,Zalińska A,Salinski A,Przybylowska-Sygut K,Kuna P,Majak P,Sysa-Jedrzejowska A,Lesiak A

    更新日期:2015-01-01 00:00:00

  • Interferon-alpha therapy for melanoma.

    abstract::Although surgery may be curative in early malignant melanoma, its effect on survival lessens with each succeeding stage of the disease. A wide variety of immunological strategies have therefore been used to improve the prognosis of patients with malignant melanoma, but adjuvant therapy with interferon (IFN)-alpha is t...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2230.2000.00559.x

    authors: Russell-Jones R

    更新日期:2000-01-01 00:00:00

  • Incipient osteomalacia occurring in chronic actinic dermatitis.

    abstract::Incipient osteomalacia developed in a Pakistani patient living in the UK after strict sunlight avoidance forming part of the management of the photosensitivity disorder, chronic actinic dermatitis. The patient's skin type and diet, which included calcium-binding phytates in chappattis, had increased his risk of the co...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2000.00669.x

    authors: Kapur N,Creamer D,Hawk J

    更新日期:2000-07-01 00:00:00

  • A 20-year epidemiological study of cutaneous melanoma in the Rijeka district of Croatia.

    abstract::A retrospective study was made of the incidence of cutaneous melanoma among the population of the district of Rijeka (Croatia) during the period 1977-96. A total of 397 patients with cutaneous melanoma was documented during this period. Over the 20-year period the incidence of the tumour increased, the mean annual rat...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2230.2000.00579.x

    authors: Zamolo G,Gruber F,Jonjić A,Cabrijan L,Palle M,Grubisić-Greblo H

    更新日期:2000-01-01 00:00:00

  • Depigmentation therapy in vitiligo universalis with cryotherapy and 4-hydroxyanisole.

    abstract::Vitiligo is a disease characterized by the loss of melanocytes, resulting in progressive depigmentation of skin, and areas of normally pigmented skin can be of cosmetic concern. Several options have been tried to remove the pigment and make the skin a more even colour. We present an easy and effective therapeutic proc...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2009.03412.x

    authors: Di Nuzzo S,Masotti A

    更新日期:2010-03-01 00:00:00

  • Acantholytic dermatosis of the vagina: the diagnostic challenge of acantholytic disease in the genital region.

    abstract::We report the case of a 24-year-old woman with an 8-month history of deep pelvic pain and postcoital bleeding. Examination revealed desquamation of the vaginal epithelium with tender fissured plaques in the vagina, initially thought to be vaginal intraepithelial neoplasia. Histology showed squamous mucosa with supraba...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/ced.13026

    authors: Kentley J,Cerio R,Khorshid M,Gibbon K

    更新日期:2017-03-01 00:00:00

  • Frontal fibrosing alopecia sparing a vascular naevus: The Renbök phenomenon.

    abstract::The Renbök phenomenon (or Inverse Köbner phenomenon) describes how the emergence of one skin condition inhibits another skin condition. The term was first coined in 1991 by Happle et al. to describe retained hair growth localised to psoriatic plaques in a patient with coexisting psoriasis and alopecia areata (AA). Sub...

    journal_title:Clinical and experimental dermatology

    pub_type: 信件

    doi:10.1111/ced.14501

    authors: Nemazee L,Harries M

    更新日期:2020-11-05 00:00:00

  • Facial ulcer treated with olanzapine.

    abstract::A 69-year-old woman presented with a nonhealing ulcer on her right cheek. On histological examination of a biopsy, no evidence of granuloma formation or malignancy was found, and the overall picture was felt to be consistent with dermatitis artefacta (DA). The patient was referred to a joint psychodermatology clinic, ...

    journal_title:Clinical and experimental dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2230.2012.04448.x

    authors: Lowry CL,Bewley A,Taylor R

    更新日期:2013-07-01 00:00:00