On the effect of heterogeneity in stochastic interacting-particle systems.

abstract：:Twisting light in both phase and intensity has recently drawn great interests in various fields related to light-matter interactions such as optical manipulation of particles and quantum entanglement of photons. Conventionally, bulky optical components are required to produce such twisted optical beams, which signific...

journal_title：Scientific reports

authors： Zhang Y,Yang X,Gao J

更新日期：2018-03-20 00:00:00

abstract：:The structure, mechanism of action and copper stoichiometry of the transmembrane sensor domain of the plant ethylene receptor ETR1 and homologs have remained elusive, hampering the understanding on how the perception of the plant hormone ethylene is transformed into a downstream signal. We generated the first structur...

journal_title：Scientific reports

authors： Schott-Verdugo S,Müller L,Classen E,Gohlke H,Groth G

更新日期：2019-06-20 00:00:00

abstract：:Plasmonic metamaterials have overcome fundamental limitations in conventional optics by their capability to engineer material resonances and dispersions at will, holding great promise for sensing applications. Recent demonstrations of metamaterial sensors, however, have mainly relied on their resonant nature for stron...

journal_title：Scientific reports

authors： Ishikawa A,Hara S,Tanaka T,Hayashi Y,Tsuruta K

更新日期：2017-06-09 00:00:00

abstract：:Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) has a dimer of dimers quaternary structure with two independent allosteric sites in each monomer. Here, we reveal the different effects of nucleotide ligands on the quaternary structure regulation and functional role of the human m-NAD(P)-ME exosite. In ...

journal_title：Scientific reports

authors： Hsieh JY,Shih WT,Kuo YH,Liu GY,Hung HC

更新日期：2019-06-24 00:00:00

abstract：:Disseminated diseases of the central nervous system such as amyotrophic lateral sclerosis (ALS) require that therapeutic agents are delivered and distributed broadly. Intrathecal route is attractive in that respect, but to date there was no methodology available allowing for optimization of this technique to assure sa...

journal_title：Scientific reports

authors： Malysz-Cymborska I,Golubczyk D,Kalkowski L,Burczyk A,Janowski M,Holak P,Olbrych K,Sanford J,Stachowiak K,Milewska K,Gorecki P,Adamiak Z,Maksymowicz W,Walczak P

更新日期：2018-11-07 00:00:00

abstract：:The interplay between the quasi 1-dimensional CuO-chains and the 2-dimensional CuO2 planes of YBa(2)Cu(3)O(6+x) (YBCO) has been in focus for a long time. Although the CuO-chains are known to be important as charge reservoirs that enable superconductivity for a range of oxygen doping levels in YBCO, the understanding o...

journal_title：Scientific reports

authors： Magnuson M,Schmitt T,Strocov VN,Schlappa J,Kalabukhov AS,Duda LC

更新日期：2014-11-12 00:00:00

abstract：:Molecular imaging technique is an attractive tool to detect liver disease at early stage. This study aims to develop a simultaneous dual-isotope single photon emission computed tomography (SPECT)/CT imaging method to assist diagnosis of hepatic tumor and liver fibrosis. Animal models of liver fibrosis and orthotopic h...

journal_title：Scientific reports

authors： Guo Z,Gao M,Zhang D,Li Y,Song M,Zhuang R,Su X,Chen G,Liu T,Liu P,Wu H,Du J,Zhang X

更新日期：2016-07-05 00:00:00

abstract：:Although extensive studies have focused on the development of acute mountain sickness (AMS), the exact mechanisms of AMS are still obscure. In this study, we used isobaric tags for relative and absolute quantitation (iTRAQ) proteomic analysis to identify novel AMS-associated biomarkers in human plasma. After 9 hours o...

journal_title：Scientific reports

authors： Lu H,Wang R,Li W,Xie H,Wang C,Hao Y,Sun Y,Jia Z

更新日期：2018-01-19 00:00:00

abstract：:The aim of this study was to investigate the characteristics of insulin producing cells (IPCs) differentiated from adipose-tissue derived stem cells (ADSCs) isolated from human subcutaneous and visceral adipose tissues and identify ADSCs suitable for differentiation into efficient and functional IPCs. Subcutaneous and...

journal_title：Scientific reports

authors： Wada Y,Ikemoto T,Morine Y,Imura S,Saito Y,Yamada S,Shimada M

更新日期：2019-09-13 00:00:00

abstract：:Jellyfish stingings are currently raising serious public health concerns around the world. Hence, the search for an effective first aid reagent for the envenomation has been the goal of many investigators in the field. There have been a few previous reports of in vivo as well as in vivo studies suggesting the metallop...

journal_title：Scientific reports

authors： Hwang DH,Lee H,Choudhary I,Kang C,Chae J,Kim E

更新日期：2020-10-29 00:00:00

abstract：:CRISPR-Cas9/gRNA exhibits therapeutic efficacy against latent human immunodeficiency virus (HIV) genome but the delivery of this therapeutic cargo to the brain remains as a challenge. In this research, for the first time, we demonstrated magnetically guided non-invasive delivery of a nano-formulation (NF), composed of...

journal_title：Scientific reports

authors： Kaushik A,Yndart A,Atluri V,Tiwari S,Tomitaka A,Gupta P,Jayant RD,Alvarez-Carbonell D,Khalili K,Nair M

更新日期：2019-03-08 00:00:00

abstract：:Exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) share similar abnormal choroidal vasculature, but responses to treatments are different. In this study, we sequenced the whole HTRA1 gene and its promoter by direct sequencing in a Hong Kong Chinese PCV cohort. We identified r...

journal_title：Scientific reports

authors： Ng TK,Liang XY,Lai TY,Ma L,Tam PO,Wang JX,Chen LJ,Chen H,Pang CP

更新日期：2016-06-24 00:00:00

abstract：:Although habitat transformation is one of the main causes of biodiversity loss, there are many examples of species successfully occupying and even proliferating in highly human-modified habitats such are the cities. Thus, there is an increasing interest in understanding the drivers favoring urban life for some species...

journal_title：Scientific reports

authors： Rebolo-Ifrán N,Tella JL,Carrete M

更新日期：2017-06-14 00:00:00

abstract：:African black-footed cats (Felis nigripes) are endangered wild felids. One male and full-sibling female African black-footed cat developed vision deficits and mydriasis as early as 3 months of age. The diagnosis of early-onset progressive retinal atrophy (PRA) was supported by reduced direct and consensual pupillary l...

journal_title：Scientific reports

authors： Oh A,Pearce JW,Gandolfi B,Creighton EK,Suedmeyer WK,Selig M,Bosiack AP,Castaner LJ,Whiting RE,Belknap EB,Lyons LA,99 Lives Consortium.

更新日期：2017-03-21 00:00:00

abstract：:Most everyday surfaces are randomly rough and self-similar on sufficiently small scales. We investigated the tactile perception of randomly rough surfaces using 3D-printed samples, where the topographic structure and the statistical properties of scale-dependent roughness were varied independently. We found that the t...

journal_title：Scientific reports

authors： Sahli R,Prot A,Wang A,Müser MH,Piovarči M,Didyk P,Bennewitz R

更新日期：2020-09-25 00:00:00

abstract：:We generated self-induced retinal ganglion cells (RGCs) with functional axons from human induced pluripotent stem cells. After development of the optic vesicle from the induced stem cell embryoid body in three-dimensional culture, conversion to two-dimensional culture, achieved by supplementation with BDNF, resulted i...

journal_title：Scientific reports

authors： Tanaka T,Yokoi T,Tamalu F,Watanabe S,Nishina S,Azuma N

更新日期：2015-02-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Colleoni F,De Santis L,Montoli E,Olivo E,Sorlien CC,Bart PJ,Gasson EGW,Bergamasco A,Sauli C,Wardell N,Prato S

更新日期：2020-06-25 00:00:00

abstract：:Radiotherapy with protons and heavier ions landmarks a novel era in the field of high-precision cancer therapy. To identify patients most benefiting from this technologically demanding therapy, fast assessment of comparative treatment plans utilizing different ion species is urgently needed. Moreover, to overcome unce...

journal_title：Scientific reports

authors： Mein S,Choi K,Kopp B,Tessonnier T,Bauer J,Ferrari A,Haberer T,Debus J,Abdollahi A,Mairani A

更新日期：2018-10-04 00:00:00

abstract：:Stochastic surface patterns form an important requirement to facilitate digital image correlation and to subsequently quantify material properties of various tissues when loaded and deformed without artefacts arising from material slippage. Depending on the samples' natural colour, a surface pattern is created by spec...

journal_title：Scientific reports

authors： Zwirner J,Ondruschka B,Scholze M,Hammer N

更新日期：2020-11-27 00:00:00

abstract：:This work provides new insights into the dynamics of silica nanoparticle-based removal of organic fluids (here oil) from naturally occurring porous media. We have used 4D (time-resolved 3D) imaging at pore-scale using X-ray computed micro-tomography (μCT) technique. The captured 3D tomographic time-series data reveal ...

journal_title：Scientific reports

authors： Pak T,Archilha NL,Mantovani IF,Moreira AC,Butler IB

更新日期：2018-07-24 00:00:00

abstract：:Large-strain elastic superhydrophobicity is highly desirable for its enhanced use performance and functional reliability in mechanically dynamic environments, but remains challenging to develop. Here we have, for the first time, proven that an elastic fibrous membrane after surface hydrophobization can maintain superh...

journal_title：Scientific reports

authors： Zhou H,Wang H,Niu H,Lin T

更新日期：2015-10-29 00:00:00

abstract：:Fluorescent probes that can distinguish different DNA topologies through changes in optical readout are sought after for DNA-based diagnostics. In this work, the 4,4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) chromophore attached to cyanophenyl substituents (BODIPY-CN) has been tethered to the 5'-end of the 15-m...

journal_title：Scientific reports

authors： Deore PS,Soldatov DV,Manderville RA

更新日期：2018-11-15 00:00:00

abstract：:Due to the increasing environmental impact of food production, carbon footprint as an indicator can guide farmland management. This study established a method and estimated the carbon footprint of grain production in China based on life cycle analysis (LCA). The results showed that grain production has a high carbon f...

journal_title：Scientific reports

authors： Zhang D,Shen J,Zhang F,Li Y,Zhang W

更新日期：2017-06-29 00:00:00

abstract：:The activation and growth of tumour-initiating cells with stem-like properties in distant organs characterize colorectal cancer (CRC) growth and metastasis. Thus, inhibition of colon cancer stem cell (CCSC) growth holds promise for CRC growth and metastasis prevention. We and others have shown that farnesyl dimethyl c...

journal_title：Scientific reports

authors： Husain K,Coppola D,Yang CS,Malafa MP

更新日期：2021-01-26 00:00:00

abstract：:The aim of the present work was to study whether the leptin-adiponectin axis may have a pathophysiological role in the increased systemic inflammation and oxidative stress observed in patients with the metabolic syndrome (MS). Leptin, adiponectin, and markers of inflammation and oxidative stress were measured in a sam...

journal_title：Scientific reports

authors： Frühbeck G,Catalán V,Rodríguez A,Ramírez B,Becerril S,Salvador J,Portincasa P,Colina I,Gómez-Ambrosi J

更新日期：2017-07-26 00:00:00

abstract：:We collected data from Kailuan cohort study from 2006 to 2011 to examine whether short-term effects of ambient temperature on heart rate (HR) and blood pressure (BP) are non-linear or linear, and their potential modifying factors. The HR, BP and individual information, including basic characteristics, life style, soci...

journal_title：Scientific reports

authors： Madaniyazi L,Zhou Y,Li S,Williams G,Jaakkola JJ,Liang X,Liu Y,Wu S,Guo Y

更新日期：2016-02-15 00:00:00

abstract：:The high metabolic activity associated with endurance flights and intense fuelling of migrant birds may produce large quantities of reactive oxygen species, which cause oxidative damage. Yet it remains unknown how long-lived birds prepare for oxidative challenges prior to extreme flights. We combined blood measurement...

journal_title：Scientific reports

authors： Gutiérrez JS,Sabat P,Castañeda LE,Contreras C,Navarrete L,Peña-Villalobos I,Navedo JG

更新日期：2019-11-26 00:00:00

abstract：:Plate subduction continuously transports crustal materials with high-δ(18)O values down to the mantle wedge, where mantle peridotites are expected to achieve the high-δ(18)O features. Elevated δ(18)O values relative to the upper mantle value have been reported for magmas from some subduction zones. However, peridotite...

journal_title：Scientific reports

authors： Liu CZ,Wu FY,Chung SL,Li QL,Sun WD,Ji WQ

更新日期：2014-02-28 00:00:00

abstract：:A highly sensitive microwave near-field sensor based on electrically-small planar resonators is proposed for highly accurate characterization of dielectric materials. The proposed sensor was developed in a robust complete-cycle topology optimization procedure wherein first the sensing area was pixelated. By maximizing...

journal_title：Scientific reports

authors： Saadat-Safa M,Nayyeri V,Ghadimi A,Soleimani M,Ramahi OM

更新日期：2019-09-16 00:00:00

abstract：:Electrical stimulation is a common adjunct used to promote bone healing; its efficacy, however, remains uncertain. We conducted a meta-analysis of randomized sham-controlled trials to establish the efficacy of electrical stimulation for bone healing. We identified all trials randomizing patients to electrical or sham ...

journal_title：Scientific reports

authors： Aleem IS,Aleem I,Evaniew N,Busse JW,Yaszemski M,Agarwal A,Einhorn T,Bhandari M

更新日期：2016-08-19 00:00:00