Abstract：
:The high metabolic activity associated with endurance flights and intense fuelling of migrant birds may produce large quantities of reactive oxygen species, which cause oxidative damage. Yet it remains unknown how long-lived birds prepare for oxidative challenges prior to extreme flights. We combined blood measurements of oxidative status and enzyme and fat metabolism in Hudsonian godwits (Limosa haemastica, a long-lived shorebird) before they embarked on non-stop flights longer than 10,000 km during their northbound migrations. We found that godwits increased total antioxidant capacity (TAC) and reduced oxidative damage (TBARS) as the pre-migratory season progressed, despite higher basal metabolic rates before departure. Elevations in plasma β-hydroxybutyrate and uric acid suggest that lipid and protein breakdown supports energetic requirements prior to migration. Significant associations between blood mitochondrial cytochrome-c oxidase and plasma TAC (negative) and TBARS (positive) during winter indicate that greater enzyme activity can result in greater oxidative damage and antioxidant responses. However enzyme activity remained unchanged between winter and premigratory stages, so birds may be unable to adjust metabolic enzyme activity in anticipation of future demands. These results indicate that godwits enhance their oxidative status during migratory preparation, which might represent an adaptation to diminish the physiological costs of long-distance migration.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Gutiérrez JS,Sabat P,Castañeda LE,Contreras C,Navarrete L,Peña-Villalobos I,Navedo JGdoi
10.1038/s41598-019-54057-6subject
Has Abstractpub_date
2019-11-26 00:00:00pages
17616issue
1issn
2045-2322pii
10.1038/s41598-019-54057-6journal_volume
9pub_type
杂志文章abstract：:Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the combination of anti-ang...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11275
更新日期：2015-06-18 00:00:00
abstract：:The high transparency of graphene, together with its good electrical conductivity and mechanical robustness, enable its use as transparent electrodes in optoelectronic devices such as solar cells. While initial demonstrations of graphene-based organic photovoltaics (OPV) have been promising, realization of scalable te...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01581
更新日期：2013-01-01 00:00:00
abstract：:Long non-coding RNAs (lncRNAs) have been implicated in human pathology, however, their role in colorectal carcinogenesis have not been fully elucidated. In the current study, whole-transcriptome analysis was performed in 3 pairs of colorectal cancer (CRC) and matched normal mucosa (NM) by RNA sequencing (RNA-seq). Fol...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18407-6
更新日期：2018-01-12 00:00:00
abstract：:Accumulating evidence indicates the association between obesity and lung function. However, no previous study has examined whether obesity affects lung function in normal weight participants with high body fat. We hypothesized that subjects with normal weight obesity (NWO) were inversely associated with lung function ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38804-3
更新日期：2019-06-20 00:00:00
abstract：:The one-stage partial nitritation and anammox process (PN/A) has been a promising microbial process to remove ammonia from wastewater especially with low carbon/nitrogen ratio. The main breakdown was the deterioration caused by overgrowth of nitrite oxidizing bacteria (NOB) resulting effluent nitrate build-up in the P...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37500
更新日期：2016-11-24 00:00:00
abstract：:We analysed the imaging findings of macular telangiectasia (MacTel) type 2 in Korea using spectral domain optical coherence tomography (SD-OCT) and investigated their relationship with visual acuity and clinical stages. A retrospective multicentre cross-sectional study was conducted in six tertiary hospitals in Korea ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73803-9
更新日期：2020-10-06 00:00:00
abstract：:FTY720 is a sphingoid base analog that acts as an anticancer agent in animal models. Its effect on tumor cells stems largely from its ability to trigger endocytosis of several nutrient transporters. The observation that FTY720 similarly stimulates downregulation of amino acid permeases in yeast suggests that the cellu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14124-2
更新日期：2017-10-23 00:00:00
abstract：:Variations of Fukushima-derived radionuclides ((90)Sr, (134)Cs and (137)Cs) in seawater and biota offshore Fukushima and in the NW Pacific Ocean were investigated and radiation doses to the Japanese and world population from ingestion of seafood contaminated by Fukushima radionuclides were estimated and compared with ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09016
更新日期：2015-03-12 00:00:00
abstract：:Selenium and selenium nanoparticles (SeNPs) are extensively used in biomedicine, electronics and some other industrial applications. The bioproduction of SeNPs is gaining interest as a green method to manufacture these biotechnologically relevant products. Several microorganisms have been used for the production of Se...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16252-1
更新日期：2017-11-22 00:00:00
abstract：:Human KHDRBS1/Sam68 is an oncogenic splicing factor involved in signal transduction and pre-mRNA splicing. We explored the molecular mechanism of KHDRBS1 to be a prognostic marker in four different cancers. Within specific cancer, including kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), acut...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47558-x
更新日期：2019-07-31 00:00:00
abstract：:The predictions for a warmer and drier climate and for increased likelihood of climate extremes raise high concerns about the possible collapse of dryland ecosystems, and about the formation of new drylands where native species are less tolerant to water stress. Using a dryland-vegetation model for plant species that ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56080-z
更新日期：2019-12-20 00:00:00
abstract：:In humans, oxytocin (OT) enhances prosocial behaviour. However, it is still unclear how the prosocial effects of OT are modulated by emotional features and/or individuals' characteristics. In a placebo-controlled design, we tested 20 healthy male volunteers to investigate these behavioural and neurophysiological modul...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00384
更新日期：2012-01-01 00:00:00
abstract：:In zebrafish, the role of matrix metalloproteinases (MMPs) in the inflammatory phase of heart regeneration following cryoinjury remains poorly understood. Here, we demonstrated an increase in MMP enzymatic activity and elevated expression of mmp9 and mmp13 in the injured area (IA) of hearts from as early as 1 day post...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25490-w
更新日期：2018-05-08 00:00:00
abstract：:Parvalbumin-containing projection neurons of the medial-septum-diagonal band of Broca ([Formula: see text]) are essential for hippocampal rhythms and learning operations yet are poorly understood at cellular and synaptic levels. We combined electrophysiological, optogenetic, and modeling approaches to investigate [For...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80245-w
更新日期：2021-01-22 00:00:00
abstract：:Tin selenide has attracted much research interest due to its unprecedentedly high thermoelectric figure of merit (ZT). For real applications, it is desirable to increase the ZT value in the lower-temperature range, as the peak ZT value currently exists near the melting point. It is shown in this paper that the structu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26193
更新日期：2016-05-19 00:00:00
abstract：:Antidiabetic medication may modify the incidence of hepatocellular carcinoma (HCC). We aimed to compare the use of different antidiabetic strategies and the incidence of HCC. PubMed, Embase.com and Cochrane Library databases were searched up to 31 October 2015 and randomized controlled trials (RCTs), cohort studies or...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析,评审
doi：10.1038/srep33743
更新日期：2016-09-19 00:00:00
abstract：:Here we report the study of two bioengineered variants of human trace amine-associated receptor 5 (hTAAR5) that were expressed in stable tetracycline-inducible HEK293S cell lines. A systematic detergent screen showed that fos-choline-14 was the optimal detergent to solubilize and subsequently purify the receptors. Mil...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00102
更新日期：2011-01-01 00:00:00
abstract：:The controllability of a network is a theoretical problem of relevance in a variety of contexts ranging from financial markets to the brain. Until now, network controllability has been characterized only on isolated networks, while the vast majority of complex systems are formed by multilayer networks. Here we build a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20706
更新日期：2016-02-12 00:00:00
abstract：:Free-surface vortices have long been studied to develop an understanding of similar rotating flow phenomena observed in nature and technology. However, a complete description of its turbulent three-dimensional flow field still remains elusive. In contrast, the related Taylor-Couette flow system has been well explicate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16950-w
更新日期：2018-01-16 00:00:00
abstract：:The prognostic factors for survival among patients with secondary osteosarcoma remain unclear. The aim of this study was to develop a practical nomogram for predicting cancer-specific survival (CSS) in patients with osteosarcoma as a secondary malignancy. The surveillance, epidemiology, and end results database was us...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69740-2
更新日期：2020-07-30 00:00:00
abstract：:Members of the Eph family of receptor tyrosine kinases have been implicated in a wide array of human cancers. The EphB4 receptor is ubiquitously expressed in head and neck squamous cell carcinoma (HNSCC) and has been shown to impart tumorigenic and invasive characteristics to these cancers. In this study, we investiga...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38792
更新日期：2016-12-12 00:00:00
abstract：:Around 350 million tonnes of plastics are annually produced worldwide. A remarkable percentage of these products is dispersed in the environment, finally reaching and dispersed in the marine environment. Recent field surveys detected microplastics' concentrations in the Mediterranean Sea. The most commonly polymers fo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74543-6
更新日期：2020-11-16 00:00:00
abstract：:Various nickel and magnesium dual-doped LiNixMg0.08Mn1.92-xO4 (x ≤ 0.15) were synthesized via a modified solid-state combustion method. All as-prepared samples show typical spinel phase with a well-defined polyhedron morphology. The Ni-Mg dual-doping obviously decreases the lattice parameter that gives rise to the lat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53494-7
更新日期：2019-11-14 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-68818-1
更新日期：2020-08-10 00:00:00
abstract：:Based on the structural complexity of ribosomes, 16S rRNA genes are considered species-specific and hence used for bacterial phylogenetic analysis. However, a growing number of reports suggest the occurrence of horizontal gene transfer, raising genealogical questions. Here we show the genetic interoperability and prom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47807-z
更新日期：2019-08-02 00:00:00
abstract：:Dissecting the complex molecular interplay between the host plant and invading virus improves our understanding of the mechanisms underlying viral pathogenesis. In this study, immunoprecipitation together with the mass spectrometry analysis revealed that the heat shock protein 70 (Hsp70) family homolog, Hsc70-2, was c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22778-9
更新日期：2018-03-14 00:00:00
abstract：:Rhodopseudomonas palustris CGA009 is a purple non-sulfur bacterium that can fix carbon dioxide (CO2) and nitrogen or break down organic compounds for its carbon and nitrogen requirements. Light, inorganic, and organic compounds can all be used for its source of energy. Excess electrons produced during its metabolic pr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49079-z
更新日期：2019-09-02 00:00:00
abstract：:Silver nanoparticles (AgNPs) demonstrating good antimicrobial activity are widely used in many fields. However, the impact of AgNPs on the community structures of marine biofilms that drive biogeochemical cycling processes and the recruitment of marine invertebrate larvae remains unknown. Here, we employed MiSeq seque...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37406
更新日期：2016-11-21 00:00:00
abstract：:Recently, graphene nanomesh (GNM) has attracted great attentions due to its unique porous structure, abundant active sites, finite band gap and possesses potential applications in the fields of electronics, gas sensor/storage, catalysis, etc. Therefore, diverse GNMs with different physical and chemical properties are ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32310
更新日期：2016-08-26 00:00:00
abstract：:Active video games (exergames) may provide short-term increase in energy expenditure. We explored the effects of gender and prior experience on aerobic and anaerobic energy systems contributions, and the activity profiles of 40 participants playing with a swimming exergame. We recorded oxygen consumption and assessed ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05583-8
更新日期：2017-07-12 00:00:00
