Glycidyl acrylate plasma glow discharged polymers.

abstract：:Previous work developing particle-based acellular, artificial antigen presenting cells (aAPCs) has focused exclusively on spherical platforms. To explore the role of shape, we generated ellipsoidal PLGA microparticles with varying aspect ratios (ARs) and synthesized aAPCs from them. The ellipsoidal biomimetic aAPCs wi...

journal_title：Biomaterials

authors： Sunshine JC,Perica K,Schneck JP,Green JJ

更新日期：2014-01-01 00:00:00

abstract：:Artificial meniscal lesions extending into the avascular part of the meniscus, which do not heal by any other means, were repaired by suturing either a porous polymer implant or a synovial flap into the defect. The implant guided the ingrowth of vascular repair tissue into the defect. This fibrous tissue later on tran...

journal_title：Biomaterials

authors： Klompmaker J,Jansen HW,Veth RP,de Groot JH,Nijenhuis AJ,Pennings AJ

更新日期：1991-11-01 00:00:00

abstract：:We studied the adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene samples. The polymer surfaces were modified by exposure to the ultraviolet light of a Xe(2)(*)-excimer lamp at a wavelength of 172 nm in an ammonia atmosphere. Treatment times were between 10 and 20...

journal_title：Biomaterials

authors： Gumpenberger T,Heitz J,Bäuerle D,Kahr H,Graz I,Romanin C,Svorcik V,Leisch F

更新日期：2003-12-01 00:00:00

abstract：:We developed cell-free implants, comprising carbodiimide crosslinked recombinant human collagen (RHC), to enable corneal regeneration by endogenous cell recruitment, to address the worldwide shortage of donor corneas. Patients were grafted with RHC implants. Over four years, the regenerated neo-corneas were stably int...

journal_title：Biomaterials

authors： Fagerholm P,Lagali NS,Ong JA,Merrett K,Jackson WB,Polarek JW,Suuronen EJ,Liu Y,Brunette I,Griffith M

更新日期：2014-03-01 00:00:00

abstract：:The purpose of this study was to determine the mechanical properties and the atomistic structures of various gelatin hydrogels as a preliminary to using these in bioengineering applications. The hydrogels were investigated as neat materials and as particulate-reinforced composites both in the as-formed state and follo...

journal_title：Biomaterials

authors： Usta M,Piech DL,MacCrone RK,Hillig WB

更新日期：2003-01-01 00:00:00

abstract：:Devices implanted within the central nervous system (CNS) are subjected to tissue reactivity due to the lack of biocompatibility between implanted material and the cells' microenvironment. Studies have attributed blood-brain barrier disruption, inflammation, and oxidative stress as main contributing factors that lead ...

journal_title：Biomaterials

authors： Bennett C,Álvarez-Ciara A,Franklin M,Dietrich WD,Prasad A

更新日期：2021-01-01 00:00:00

abstract：:We have developed a silver-releasing biomaterial with promising potential for wound healing applications. The material is made of ultrashort peptides which can self-assemble in water to form hydrogels. Silver nanoparticles (Ag NPs) were synthesized in situ within the biomaterial, using only UV irradiation and no addit...

journal_title：Biomaterials

authors： Reithofer MR,Lakshmanan A,Ping AT,Chin JM,Hauser CA

更新日期：2014-08-01 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by the loss of neurogenesis and excessive induction of apoptosis. The induction of neurogenesis and inhibition of apoptosis may be a promising therapeutic approach to combating the disease. Celecoxib (CB), a cyclooxygenase-2 specific inhibitor, could offer neuroprotection. Spe...

journal_title：Biomaterials

authors： Guo JW,Guan PP,Ding WY,Wang SL,Huang XS,Wang ZY,Wang P

更新日期：2017-11-01 00:00:00

abstract：:The immune system is a powerful resource for the eradication of cancer, but to overcome the low immunogenicity of tumor cells, a sufficiently strong CD8(+) T cell-mediated adaptive immune response is required. Nanoparticulate biomaterials represent a potentially effective delivery system for cancer vaccines, as they c...

journal_title：Biomaterials

authors： Molino NM,Neek M,Tucker JA,Nelson EL,Wang SW

更新日期：2016-04-01 00:00:00

abstract：:Thrombomodulin (TM) is a newly described endothelial cell-associated protein that functions as a potent natural anticoagulant by converting thrombin from a procoagulant protease to an anticoagulant. In this study, focussing on the application of TM for biomedical materials, recombinant human TM (hTM) was immobilized o...

journal_title：Biomaterials

authors： Kishida A,Ueno Y,Fukudome N,Yashima E,Maruyama I,Akashi M

更新日期：1994-08-01 00:00:00

abstract：:Potential applications of engineered, functional, cardiac muscle extends from basic research through drug discovery to engineering heart tissue for transplantation. One of the central questions in cardiac tissue engineering is to understand and control the complex interactions between the cardiac muscle cells and thei...

journal_title：Biomaterials

authors： Das M,Molnar P,Gregory C,Riedel L,Jamshidi A,Hickman JJ

更新日期：2004-11-01 00:00:00

abstract：:Nanobubbles, as a kind of new ultrasound contrast agent (UCAs), have shown promise to penetrate tumor vasculature to allow for targeted imaging. However, their inherent physical instability is an ongoing concern that could weaken their imaging ability with ultrasound. Gas vesicles (GVs), which are genetically encoded,...

journal_title：Biomaterials

authors： Wang G,Song L,Hou X,Kala S,Wong KF,Tang L,Dai Y,Sun L

更新日期：2020-04-01 00:00:00

abstract：:Islet transplantation is considered the most promising treatment for type 1 diabetes. However, the clinical success is limited by islet dysfunction in long-term culture. In this study, we have utilized the rapid self-gelation and injectability offered by blending of mulberry silk (Bombyx mori) with non-mulberry (Anthe...

journal_title：Biomaterials

authors： Kumar M,Gupta P,Bhattacharjee S,Nandi SK,Mandal BB

更新日期：2018-12-01 00:00:00

abstract：:The design of peptide-based subunit vaccine formulations for the direct delivery of tumor antigen peptides (Aps) to dendritic cells (DCs) localized within draining lymph nodes (DLNs) is challenging. Mature DCs (mDCs) are abundantly distributed within DLNs but have dramatically reduced endocytic uptake and antigen-proc...

journal_title：Biomaterials

authors： Qian Y,Jin H,Qiao S,Dai Y,Huang C,Lu L,Luo Q,Zhang Z

更新日期：2016-08-01 00:00:00

abstract：:Metronomic chemotherapy, which is defined as a low-dose and frequent administration of cytotoxic drugs without drug-free breaks, has been recently emerged as an alternative to traditional MTD therapy and has shown therapeutic benefit in breast cancer patients in numbers of clinical studies. Unlike MTD, metronomic chem...

journal_title：Biomaterials

authors： Chung SW,Kim GC,Kweon S,Lee H,Choi JU,Mahmud F,Chang HW,Kim JW,Son WC,Kim SY,Byun Y

更新日期：2018-11-01 00:00:00

abstract：:Collagen has been widely used for tissue engineering. Here, we applied bioactive laminin-derived peptides as an additive for collagen, laminin-111, and fibronectin matrices resulting in peptide/collagen, peptide/laminin-111, and peptide/fibronectin matrices. Several syndecan-binding peptides, including AG73 (RKRLQVQLS...

journal_title：Biomaterials

authors： Yamada Y,Katagiri F,Hozumi K,Kikkawa Y,Nomizu M

更新日期：2011-07-01 00:00:00

abstract：:Neural tissue engineering holds great promise in repairing damaged nerve tissues. However, despite the promising results in regenerating the injured nervous system, tissue engineering approaches are still insufficient to result in full functional recovery in severe nerve damages. Majority of these approaches only focu...

journal_title：Biomaterials

authors： Chooi WH,Chew SY

更新日期：2019-03-01 00:00:00

abstract：:Implantation of synthetic material, including vascular grafts, pacemakers, etc. results in the foreign body reaction and the formation of multinucleated giant cells (MGCs) at the exterior surface of the implant. Despite the long-standing premise that fusion of mononucleated macrophages results in the formation of MGCs...

journal_title：Biomaterials

authors： Faust JJ,Christenson W,Doudrick K,Ros R,Ugarova TP

更新日期：2017-06-01 00:00:00

abstract：:Photolithography is the current workhorse for the microelectronic industry. It has been used extensively for the creation of patterns on two-dimensional surfaces. Various research groups have studied the use of photolithography to pattern surfaces for the alignment of cells. So far, these applications have been limite...

journal_title：Biomaterials

authors： He W,Halberstadt CR,Gonsalves KE

更新日期：2004-05-01 00:00:00

abstract：:The role of albumin in the mineralisation process of commercial hydroxyapatite (HAp) and synthesised biphasic (HAp-tricalcium phosphate) ceramics in a bufferless simulated inorganic plasma (HBSS) was investigated by conventional in vitro tests and static and dynamic wettability measurements. Albumin was either pre-ads...

journal_title：Biomaterials

authors： Marques PA,Serro AP,Saramago BJ,Fernandes AC,Magalhães MC,Correia RN

更新日期：2003-02-01 00:00:00

abstract：:A series of novel cationic star polymers were synthesized by conjugating multiple oligoethylenimine (OEI) arms onto an alpha-cyclodextrin (alpha-CD) core as nonviral gene delivery vectors. The molecular structures of the alpha-CD-OEI star polymers, which contained linear or branched OEI arms with different chain lengt...

journal_title：Biomaterials

authors： Yang C,Li H,Goh SH,Li J

更新日期：2007-07-01 00:00:00

abstract：:The generation of intracellular reactive oxygen species (ROS) was optically monitored using ROS-sensitive gold nanoprobes in response to an exposure of nanoparticles (NPs). Fluorescent dye-labeled hyaluronic acid was grafted onto the surface of gold nanoparticles (HF-AuNPs) for imaging intracellular ROS. The ultrasens...

journal_title：Biomaterials

authors： Lee K,Lee H,Lee KW,Park TG

更新日期：2011-04-01 00:00:00

abstract：:Particulate wear debris of artificial joints, metallic and plastic, and solutions of metals in body fluids are known to have adverse effects. Encapsulation of the articulating parts would prevent wear debris from entering the surrounding tissue and check tissue ingrowth into the joint. The capsule could contain an art...

journal_title：Biomaterials

authors： Derbyshire B,Skorecki J,Wheble VH

更新日期：1980-01-01 00:00:00

abstract：:Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells protect vertebrates by killing infected or transformed cells using granzyme B (GrB) to induce apoptosis. However, GrB-induced apoptosis of target cells causes inflammatory disease and chronic transplant rejection and so is an important disease target. The aim...

journal_title：Biomaterials

authors： Cheng W,Yang C,Hedrick JL,Williams DF,Yang YY,Ashton-Rickardt PG

更新日期：2013-05-01 00:00:00

abstract：:Arterial smooth muscle cell (SMC) phenotype and proliferation is regulated by their surrounding collagens, which transform from fibrillar to monomeric type in atherogenesis, and platelet-derived growth factor (PDGF)-BB/interleukin (IL)-1β. This study aims at elucidating the mechanisms by which physical (monomeric vs. ...

journal_title：Biomaterials

authors： Yeh YT,Lee CI,Lim SH,Chen LJ,Wang WL,Chuang YJ,Chiu JJ

更新日期：2012-10-01 00:00:00

abstract：:This animal study (domestic pig) examined the bone formation after filling defined defects with autogenous bone or a collagen lyophilisat in combination with Platelet-rich-plasma (PRP) by evaluating bone matrix proteins. Six groups, both materials with and without PRP in two concentrations (+ 1, + 2) were compared to ...

journal_title：Biomaterials

authors： Thorwarth M,Rupprecht S,Falk S,Felszeghy E,Wiltfang J,Schlegel KA

更新日期：2005-05-01 00:00:00

abstract：:This study examined the antibacterial activity of prepolymerized resin filler, in which the bactericide quaternary ammonium was immobilized. The experimental filler was prepared by grinding prepolymerized resin blocks of methacrylate monomers, silica particles, and the antibacterial monomer methacryloyloxydodecylpyrid...

journal_title：Biomaterials

authors： Imazato S,Ebi N,Takahashi Y,Kaneko T,Ebisu S,Russell RR

更新日期：2003-09-01 00:00:00

abstract：:The successful delivery of anti-cancer drugs relies on the simultaneous capability to actively target a specific location, a sufficient lifetime in the active form in the circulation, and traceability and quantification of drug distribution via in vivo medical imaging. Herein, a highly magnetic nanocarrier (HMNC) comp...

journal_title：Biomaterials

authors： Yang HW,Hua MY,Liu HL,Huang CY,Tsai RY,Lu YJ,Chen JY,Tang HJ,Hsien HY,Chang YS,Yen TC,Chen PY,Wei KC

更新日期：2011-09-01 00:00:00

abstract：:Right femoral, cortical bone osteotomies of 42 rabbits were fixed with fibrillated, self-reinforced (SR) poly-L-lactide (PLLA) rods, 4.5 mm in diameter. Follow-up times were from 3 to 48 wk. None of the rods broke during this period. There was one non-union at three weeks and one non-union at 12 weeks. Radiographic, h...

journal_title：Biomaterials

authors： Manninen MJ,Pohjonen T

更新日期：1993-01-01 00:00:00

abstract：:Multiwalled carbon nanotubes (MWCNTs) are cut short and grafted with polyethylenimine (PEI) for further covalent conjugation to fluorescein isothiocyanate (FITC) and prostate stem cell antigen (PSCA) monoclonal antibody (mAb). The in vitro and in vivo toxicity data reveal that the as-prepared CNT-PEI(FITC)-mAb has goo...

journal_title：Biomaterials

authors： Wu H,Shi H,Zhang H,Wang X,Yang Y,Yu C,Hao C,Du J,Hu H,Yang S

更新日期：2014-07-01 00:00:00