Abstract:
:We studied the adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene samples. The polymer surfaces were modified by exposure to the ultraviolet light of a Xe(2)(*)-excimer lamp at a wavelength of 172 nm in an ammonia atmosphere. Treatment times were between 10 and 20 min. The endothelial cell density was determined 1, 3 and 8 days after seeding by image analysis. Surface modification of the samples resulted in a significant increase in the number of adhering cells and in the formation of a confluent cell layer after 3-8 days. The results were comparable than those obtained on polystyrene Petri dishes, which are used as standard substrates in cell cultivation. Thus modified PTFE appears to be a promising material for the fabrication of artificial vascular prostheses coated with endothelial cells.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Gumpenberger T,Heitz J,Bäuerle D,Kahr H,Graz I,Romanin C,Svorcik V,Leisch Fdoi
10.1016/s0142-9612(03)00460-5keywords:
subject
Has Abstractpub_date
2003-12-01 00:00:00pages
5139-44issue
28eissn
0142-9612issn
1878-5905pii
S0142961203004605journal_volume
24pub_type
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