Abstract：
:Cyanide is a powerful chemical asphyxiant found in some forensic cases following voluntary (suicide) or involuntary ingestion (fire, accidental exposure). A quantification method for cyanide that is specifically suited to post-mortem forensic purposes was developed. Determination was performed by headspace gas chromatography coupled to mass spectrometry using a GS-GASPRO column on an HP-6890 gas chromatograph with an HP-5973N mass detector. The biological sample was treated with an internal standard, frozen, glacial acetic acid was added and the sample was then incubated at 60°C for 15 min. The headspace was sampled with a disposable syringe, and analyzed to quantify hydrogen cyanide. Isotopically labeled cyanide ((13)C(15)N) was used as the internal standard to minimize matrix effect and sampling error. The method produced an extended linear dynamic range (0.07-50 μg/mL), and a method detection limit of 0.02 μg/mL. Identical calibration curves were obtained when blood, gastric contents and aqueous solutions were used as the calibration standard matrix. This method was also successful in quantitating cyanide in gastric contents, one of the most variable biological fluids. The method has been validated and is being used for current forensic cases such as fire victims and suicides.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Desharnais B,Huppé G,Lamarche M,Mireault P,Skinner CDdoi
10.1016/j.forsciint.2012.06.017subject
Has Abstractpub_date
2012-10-10 00:00:00pages
346-51issue
1-3eissn
0379-0738issn
1872-6283pii
S0379-0738(12)00317-9journal_volume
222pub_type
杂志文章abstract：:We examined the immunohistochemical distributions of ubiquitin (Ub) and myoglobin (Mb) in human kidney tissues to assist the pathological assessment of death due to trauma. Medicolegal autopsy cases at our institute (n=138: 0-96 years of age, 105 males and 33 females) were examined. Causes of death were blunt injury (...
journal_title：Forensic science international
pub_type： 杂志文章
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.04.008
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.08.002
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：1990-04-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.10.032
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journal_title：Forensic science international
pub_type： 杂志文章
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.04.022
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.10.032
更新日期：2019-01-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.06.032
更新日期：2007-04-11 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.04.031
更新日期：2014-08-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.03.018
更新日期：2018-05-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.04.007
更新日期：2017-06-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.09.005
更新日期：2013-12-10 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.08.006
更新日期：2007-07-04 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.109916
更新日期：2019-09-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(88)90152-1
更新日期：1988-02-01 00:00:00
abstract：:In 2017, 47,600 overdose deaths were reported to be associated with the abuse of opioids, including prescription painkillers (e.g. oxycodone), opiates (e.g. heroin), or synthetic opioids (e.g. fentanyl) within the United States. The recent spike in the presence of synthetic opioids in lots of heroin distributed on the...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.04.019
更新日期：2019-07-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.07.023
更新日期：2010-03-20 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.03.003
更新日期：2010-06-15 00:00:00
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pub_type： 杂志文章
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：1995-11-30 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章,评审
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更新日期：2006-06-02 00:00:00
abstract：:The comparison of two or more samples of liquid gasoline (petrol) to establish a common origin is a difficult problem in the forensic investigation of arsons and suspicious fires. A total of 35 randomly collected samples of unevaporated gasoline, covering three different grades (regular unleaded, premium unleaded and ...
journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2003-06-24 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2001-05-15 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00401-1
更新日期：2001-06-15 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：1992-11-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2011-07-15 00:00:00
abstract：:Two amphetamine-like piperazine-containing compounds, 1-(3,4-methylenedioxyphenyl)-2-piperazinopropane (3,4-MDPPP), its positional isomer 1-(2,3-methylenedioxyphenyl)-2-piperazinopropane (2,3-MDPPP) and three methcathinone-like piperazine-containing regioisomeric ring substituted 1-(methoxyphenyl)-2-piperazinopropanon...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.11.015
更新日期：2014-02-01 00:00:00
